Drug Description in Trials / DrugBank / KEGG DRUG


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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1Adempas[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[5] 51, 86, 88, 225, 299 💬
2Adempas (Riociguat, BAY63-2521)[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 86, 88 💬
3ADEMPAS - 0,5 MG - COMPRESSA RIVESTITA CON FILM - USO ORALE - BLISTER (PP/ALU) - 42 COMPRESSE[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
4ADEMPAS - 1 MG - COMPRESSA RIVESTITA CON FILM - USO ORALE - BLISTER (PP/ALU) - 42 COMPRESSE[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 51, 86 💬
5ADEMPAS - 1,5 MG - COMPRESSA RIVESTITA CON FILM - USO ORALE - BLISTER (PP/ALU) - 42 COMPRESSE[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 51, 86 💬
6ADEMPAS - 2 MG - COMPRESSA RIVESTITA CON FILM - USO ORALE - BLISTER (PP/ALU) - 42 COMPRESSE[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 51, 86 💬
7ADEMPAS - 2,5 MG - COMPRESSA RIVESTITA CON FILM - USO ORALE - BLISTER (PP/ALU) - 42 COMPRESSE[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 51, 86 💬
8Adempas 0.125 mg[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 299 💬
9Adempas 0.5 mg[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 86, 299 💬
10Adempas 0.5 mg Film Coated Tablet[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
11Adempas 1 mg Film Coated Tablet[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
12Adempas 1.0 mg[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 86, 299 💬
13Adempas 1.5 mg[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
14Adempas 1.5 mg Film Coated Tablet[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
15Adempas 2 mg Film Coated Tablet[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
16Adempas 2.0 mg[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 86, 299 💬
17Adempas 2.5 mg[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
18Adempas 2.5 mg Film Coated Tablet[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
19Adempas®[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 86, 88 💬
20Adempas® 0.5 mg film-coated tablets[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
21Adempas® 1.0 mg film-coated tablets[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
22Adempas® 1.5 mg film-coated tablets[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
23Adempas® 2.0 mg film-coated tablets[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
24Adempas® 2.5 mg film-coated tablets[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
25Adempas¿ 0.5 mg compressa rivestita con film[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
26Adempas¿ 1.0[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
27Adempas¿ 1.5 mg[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
28Adempas¿ 2.0 mg[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
29Adempas¿ 2.5 mg[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
30RIOCIGUAT
(Adempas (TN))
[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[6] 51, 84, 86, 88, 225, 299 💬
31Riociguat (Adempas, BAY63-2521)[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[4] 51, 86, 88, 299 💬
32Riociguat (BAY63-2521)
(Adempas (TN))
[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
33Riociguat coated tablet 0.5 mg
(Adempas (TN))
[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 51 💬
34Riociguat coated tablet 1.0 mg
(Adempas (TN))
[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 51 💬
35Riociguat coated tablet 1.5 mg
(Adempas (TN))
[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 51 💬
36Riociguat coated tablet 2.0 mg
(Adempas (TN))
[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 51 💬
37Riociguat coated tablet 2.5 m
(Adempas (TN))
[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 51 💬
38Riociguat coated tablet 2.5 mg
(Adempas (TN))
[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 51 💬
39Riociguat granules 0.3% for oral application
(Adempas (TN))
[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
40Riociguat Oral Product
(Adempas (TN))
[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
41Riociguat Oral Tablet
(Adempas (TN))
[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[3] 51, 86, 88 💬
42Riociguat Pill
(Adempas (TN))
[1] Riociguat (Adempas)[1] Riociguat (Adempas (TN)) 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬