Drug Description in Trials / DrugBank / KEGG DRUG

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No.

Drug (Description in trials)

DrugBank

KEGG DRUG

KEGG GENES

KEGG PATHWAY

Disease ID

1

[1] Leflunomide (Arava)

[1] Leflunomide (Arava (TN)) 💬

[1] DHODH 💬

[3] Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬

[3] 46, 53, 162 💬

2

Arava 20 mg filmdrasjerte tabletter

-

-

-

-

[1] 46 💬

3

Arava 20 mg Tablets (Aventis Pharmaceutical, Inc.)

[1] Leflunomide (Arava)

[1] Leflunomide (Arava (TN)) 💬

[1] DHODH 💬

[3] Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬

[1] 46 💬

4

[1] Leflunomide (Arava)

[1] Leflunomide (Arava (TN)) 💬

[1] DHODH 💬

[3] Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬

[1] 46 💬

5

Leflunomide
(Arava (TN))

[1] Leflunomide (Arava)

[1] Leflunomide (Arava (TN)) 💬

[1] DHODH 💬

[3] Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬

[12] 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300 💬

Disease ID	Name
11	Myasthenia gravis
40	Takayasu arteritis
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
53	Sjogren syndrome
66	IgA nephropathy
107	Juvenile idiopathic arthritis
162	Pemphigoid
224	Purpura nephritis
270	Chronic recurrent multifocal osteomyelitis
271	Ankylosing spondylitis
300	IgG4-related disease

6

Leflunomide (permitted, not necessary)
(Arava (TN))

[1] Leflunomide (Arava)

[1] Leflunomide (Arava (TN)) 💬

[1] DHODH 💬

[3] Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬

[1] 46 💬

7

Leflunomide 20 mg Tablets (Geneva Pharmaceutical)
(Arava (TN))

[1] Leflunomide (Arava)

[1] Leflunomide (Arava (TN)) 💬

[1] DHODH 💬

[3] Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬

[1] 46 💬

8

Leflunomide 20 mg+prednisone 0.5mg/kg/d
(Arava (TN))

[2] Leflunomide (Arava),
Prednisone

[2] Prednisone ,
Leflunomide (Arava (TN)) 💬

[2] DHODH,
NR3C1 💬

[4] Biosynthesis of cofactors, Metabolic pathways, Neuroactive ligand-receptor interaction, Pyrimidine metabolism 💬

[1] 66 💬

9

Leflunomide 20Mg Tab
(Arava (TN))

[1] Leflunomide (Arava)

[1] Leflunomide (Arava (TN)) 💬

[1] DHODH 💬

[3] Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬

[1] 46 💬

10

Leflunomide 20mg/d
(Arava (TN))

[1] Leflunomide (Arava)

[1] Leflunomide (Arava (TN)) 💬

[1] DHODH 💬

[3] Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬

[1] 53 💬

11

Leflunomide Mylan
(Arava (TN))

[1] Leflunomide (Arava)

[1] Leflunomide (Arava (TN)) 💬

[1] DHODH 💬

[3] Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬

[1] 53 💬

12

Leflunomide(LEF)
(Arava (TN))

[1] Leflunomide (Arava)

[1] Leflunomide (Arava (TN)) 💬

[1] DHODH 💬

[3] Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬

[1] 224 💬

13

Leflunomide-Sulfasalazine-Hydroxychloroquine
(Arava (TN))

[3] Hydroxychloroquine,
Leflunomide (Arava),
Sulfasalazine

[3] Sulfasalazine ,
Leflunomide (Arava (TN)),
Hydroxychloroquine 💬

[1] DHODH 💬

[3] Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬

[1] 46 💬