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No.
Drug (Description in trials)
DrugBank
KEGG DRUG
KEGG GENES
KEGG PATHWAY
Disease ID
1
Ambrisentan
[1]
Ambrisentan
Ambrisentan
[1]
Ambrisentan
Ambrisentan
💬
1.
Ambrisentan
×
Name
Other Names
Ambrisentan
Ambrisentan (JAN/INN)
Letairis (TN)
Volibris (TN)
[1]
EDNRA
EDNRA
💬
1.
Ambrisentan
×
Name
Full Name
EDNRA
endothelin receptor type A
[7]
Calcium signaling pathway
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Renin secretion
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
[7]
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Renin se
...
[7]
51
51
,
84
,
85
,
86
,
88
,
210
,
211
💬
1.
Ambrisentan
×
Disease ID
Name
51
Scleroderma
84
Sarcoidosis
85
Idiopathic interstitial pneumonia
86
Pulmonary arterial hypertension
88
Chronic thromboembolic pulmonary hypertension
210
Single Ventricle
211
Hypoplastic left heart syndrome
2
Ambrisentan
- high dose
[1]
Ambrisentan
Ambrisentan
[1]
Ambrisentan
Ambrisentan
💬
2.
Ambrisentan
- high dose
×
Name
Other Names
Ambrisentan
Ambrisentan (JAN/INN)
Letairis (TN)
Volibris (TN)
[1]
EDNRA
EDNRA
💬
2.
Ambrisentan
- high dose
×
Name
Full Name
EDNRA
endothelin receptor type A
[7]
Calcium signaling pathway
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Renin secretion
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
[7]
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Renin se
...
[1]
86
86
💬
2.
Ambrisentan
- high dose
×
Disease ID
Name
86
Pulmonary arterial hypertension
3
Ambrisentan
- low dose
[1]
Ambrisentan
Ambrisentan
[1]
Ambrisentan
Ambrisentan
💬
3.
Ambrisentan
- low dose
×
Name
Other Names
Ambrisentan
Ambrisentan (JAN/INN)
Letairis (TN)
Volibris (TN)
[1]
EDNRA
EDNRA
💬
3.
Ambrisentan
- low dose
×
Name
Full Name
EDNRA
endothelin receptor type A
[7]
Calcium signaling pathway
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Renin secretion
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
[7]
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Renin se
...
[1]
86
86
💬
3.
Ambrisentan
- low dose
×
Disease ID
Name
86
Pulmonary arterial hypertension
4
Ambrisentan
5 mg
[1]
Ambrisentan
Ambrisentan
[1]
Ambrisentan
Ambrisentan
💬
4.
Ambrisentan
5 mg
×
Name
Other Names
Ambrisentan
Ambrisentan (JAN/INN)
Letairis (TN)
Volibris (TN)
[1]
EDNRA
EDNRA
💬
4.
Ambrisentan
5 mg
×
Name
Full Name
EDNRA
endothelin receptor type A
[7]
Calcium signaling pathway
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Renin secretion
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
[7]
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Renin se
...
[1]
88
88
💬
4.
Ambrisentan
5 mg
×
Disease ID
Name
88
Chronic thromboembolic pulmonary hypertension
5
Ambrisentan
5 mg film-coated tablets
[1]
Ambrisentan
Ambrisentan
[1]
Ambrisentan
Ambrisentan
💬
5.
Ambrisentan
5 mg film-coated tablets
×
Name
Other Names
Ambrisentan
Ambrisentan (JAN/INN)
Letairis (TN)
Volibris (TN)
[1]
EDNRA
EDNRA
💬
5.
Ambrisentan
5 mg film-coated tablets
×
Name
Full Name
EDNRA
endothelin receptor type A
[7]
Calcium signaling pathway
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Renin secretion
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
[7]
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Renin se
...
[1]
86
86
💬
5.
Ambrisentan
5 mg film-coated tablets
×
Disease ID
Name
86
Pulmonary arterial hypertension
6
Ambrisentan
5mg film-coated tablets [marketed product]
[1]
Ambrisentan
Ambrisentan
[1]
Ambrisentan
Ambrisentan
💬
6.
Ambrisentan
5mg film-coated tablets [marketed product]
×
Name
Other Names
Ambrisentan
Ambrisentan (JAN/INN)
Letairis (TN)
Volibris (TN)
[1]
EDNRA
EDNRA
💬
6.
Ambrisentan
5mg film-coated tablets [marketed product]
×
Name
Full Name
EDNRA
endothelin receptor type A
[7]
Calcium signaling pathway
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Renin secretion
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
[7]
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Renin se
...
[1]
86
86
💬
6.
Ambrisentan
5mg film-coated tablets [marketed product]
×
Disease ID
Name
86
Pulmonary arterial hypertension
7
Ambrisentan
plus Spironolactone
[2]
Ambrisentan
Ambrisentan
,
Spironolactone
[2]
Spironolactone
Spironolactone
,
Ambrisentan
💬
7.
Ambrisentan
plus Spironolactone
×
Name
Other Names
Spironolactone
Spironolactone (JP18/USP/INN)
Aldactone (TN)
CAROSPIR
Ambrisentan
Ambrisentan (JAN/INN)
Letairis (TN)
Volibris (TN)
[2]
EDNRA
EDNRA
,
NR3C2
💬
7.
Ambrisentan
plus Spironolactone
×
Name
Full Name
EDNRA
endothelin receptor type A
NR3C2
nuclear receptor subfamily 3 group C member 2
[8]
Aldosterone-regulated sodium reabsorption
Aldosterone-regulated sodium reabsorption
,
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Renin secretion
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
[8]
Aldosterone-regulated sodium reabsorption
,
Calcium signaling pathway
,
Neuroactive ligand-recepto
...
[1]
86
86
💬
7.
Ambrisentan
plus Spironolactone
×
Disease ID
Name
86
Pulmonary arterial hypertension
8
Ambrisentan
Tablet
[1]
Ambrisentan
Ambrisentan
[1]
Ambrisentan
Ambrisentan
💬
8.
Ambrisentan
Tablet
×
Name
Other Names
Ambrisentan
Ambrisentan (JAN/INN)
Letairis (TN)
Volibris (TN)
[1]
EDNRA
EDNRA
💬
8.
Ambrisentan
Tablet
×
Name
Full Name
EDNRA
endothelin receptor type A
[7]
Calcium signaling pathway
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Renin secretion
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
[7]
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Renin se
...
[1]
86
86
💬
8.
Ambrisentan
Tablet
×
Disease ID
Name
86
Pulmonary arterial hypertension
9
Bosentan,
Ambrisentan
[2]
Ambrisentan
Ambrisentan
,
Bosentan
[3]
Bosentan
Bosentan
,
Ambrisentan
,
Bosentan
💬
9. Bosentan,
Ambrisentan
×
Name
Other Names
Bosentan
Bosentan (USAN)
Bosentan hydrate (JAN)
Tracleer (TN)
Ambrisentan
Ambrisentan (JAN/INN)
Letairis (TN)
Volibris (TN)
Bosentan
Bosentan (INN)
[2]
EDNRA
EDNRA
,
EDNRB
💬
9. Bosentan,
Ambrisentan
×
Name
Full Name
EDNRA
endothelin receptor type A
EDNRB
endothelin receptor type B
[9]
Calcium signaling pathway
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Relaxin signaling pathway
,
Renin secretion
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
[9]
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in c
...
[1]
86
86
💬
9. Bosentan,
Ambrisentan
×
Disease ID
Name
86
Pulmonary arterial hypertension
10
Tadalafil and
ambrisentan
upfront combination therapy
[2]
Ambrisentan
Ambrisentan
,
Tadalafil
[2]
Tadalafil
Tadalafil
,
Ambrisentan
💬
10. Tadalafil and
ambrisentan
upfront combination therapy
×
Name
Other Names
Tadalafil
Tadalafil (JAN/USP/INN)
Adcirca (TN)
Cialis (TN)
Zalutia (TN)
TADLIQ
ALYQ
Ambrisentan
Ambrisentan (JAN/INN)
Letairis (TN)
Volibris (TN)
[2]
EDNRA
EDNRA
,
PDE5A
💬
10. Tadalafil and
ambrisentan
upfront combination therapy
×
Name
Full Name
EDNRA
endothelin receptor type A
PDE5A
phosphodiesterase 5A
[9]
Calcium signaling pathway
Calcium signaling pathway
,
Metabolic pathways
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Purine metabolism
,
Renin secretion
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
[9]
Calcium signaling pathway
,
Metabolic pathways
,
Neuroactive ligand-receptor interaction
,
Pathways
...
[2]
51
51
,
86
💬
10. Tadalafil and
ambrisentan
upfront combination therapy
×
Disease ID
Name
51
Scleroderma
86
Pulmonary arterial hypertension