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Showing 1 to 10 of 16 descriptions
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No.
Drug (Description in trials)
DrugBank
KEGG DRUG
KEGG GENES
KEGG PATHWAY
Disease ID
1
ACT-064992 (
macitentan
)
[1]
Macitentan
Macitentan
[1]
Macitentan
Macitentan
💬
1. ACT-064992 (
macitentan
)
×
Name
Other Names
Macitentan
Macitentan (JAN/USAN)
Opsumit (TN)
[2]
EDNRA
EDNRA
,
EDNRB
💬
1. ACT-064992 (
macitentan
)
×
Name
Full Name
EDNRA
endothelin receptor type A
EDNRB
endothelin receptor type B
[9]
Calcium signaling pathway
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Relaxin signaling pathway
,
Renin secretion
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
[9]
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in c
...
[1]
85
85
💬
1. ACT-064992 (
macitentan
)
×
Disease ID
Name
85
Idiopathic interstitial pneumonia
2
ERA and PDE-5I (Sildenafil, Tadalafil, Bosentan,
Macitentan
)
[4]
Bosentan
Bosentan
,
Macitentan
,
Sildenafil
,
Tadalafil
[5]
Bosentan
Bosentan
,
Tadalafil
,
Bosentan
,
Sildenafil
,
Macitentan
💬
2. ERA and PDE-5I (Sildenafil, Tadalafil, Bosentan,
Macitentan
)
×
Name
Other Names
Bosentan
Bosentan (USAN)
Bosentan hydrate (JAN)
Tracleer (TN)
Tadalafil
Tadalafil (JAN/USP/INN)
Adcirca (TN)
Cialis (TN)
Zalutia (TN)
TADLIQ
ALYQ
Bosentan
Bosentan (INN)
Sildenafil
Sildenafil (INN)
Aphrodil (TN)
Macitentan
Macitentan (JAN/USAN)
Opsumit (TN)
[3]
EDNRA
EDNRA
,
EDNRB
,
PDE5A
💬
2. ERA and PDE-5I (Sildenafil, Tadalafil, Bosentan,
Macitentan
)
×
Name
Full Name
EDNRA
endothelin receptor type A
EDNRB
endothelin receptor type B
PDE5A
phosphodiesterase 5A
[11]
Calcium signaling pathway
Calcium signaling pathway
,
Melanogenesis
,
Metabolic pathways
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Purine metabolism
,
Relaxin signaling pathway
,
Renin secretion
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
[11]
Calcium signaling pathway
,
Melanogenesis
,
Metabolic pathways
,
Neuroactive ligand-receptor inter
...
[1]
86
86
💬
2. ERA and PDE-5I (Sildenafil, Tadalafil, Bosentan,
Macitentan
)
×
Disease ID
Name
86
Pulmonary arterial hypertension
3
FDC
macitentan
/tadalafil
[2]
Macitentan
Macitentan
,
Tadalafil
[2]
Tadalafil
Tadalafil
,
Macitentan
💬
3. FDC
macitentan
/tadalafil
×
Name
Other Names
Tadalafil
Tadalafil (JAN/USP/INN)
Adcirca (TN)
Cialis (TN)
Zalutia (TN)
TADLIQ
ALYQ
Macitentan
Macitentan (JAN/USAN)
Opsumit (TN)
[3]
EDNRA
EDNRA
,
EDNRB
,
PDE5A
💬
3. FDC
macitentan
/tadalafil
×
Name
Full Name
EDNRA
endothelin receptor type A
EDNRB
endothelin receptor type B
PDE5A
phosphodiesterase 5A
[11]
Calcium signaling pathway
Calcium signaling pathway
,
Melanogenesis
,
Metabolic pathways
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Purine metabolism
,
Relaxin signaling pathway
,
Renin secretion
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
[11]
Calcium signaling pathway
,
Melanogenesis
,
Metabolic pathways
,
Neuroactive ligand-receptor inter
...
[1]
86
86
💬
3. FDC
macitentan
/tadalafil
×
Disease ID
Name
86
Pulmonary arterial hypertension
4
Macitentan
[1]
Macitentan
Macitentan
[1]
Macitentan
Macitentan
💬
4.
Macitentan
×
Name
Other Names
Macitentan
Macitentan (JAN/USAN)
Opsumit (TN)
[2]
EDNRA
EDNRA
,
EDNRB
💬
4.
Macitentan
×
Name
Full Name
EDNRA
endothelin receptor type A
EDNRB
endothelin receptor type B
[9]
Calcium signaling pathway
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Relaxin signaling pathway
,
Renin secretion
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
[9]
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in c
...
[5]
51
51
,
85
,
86
,
88
,
210
💬
4.
Macitentan
×
Disease ID
Name
51
Scleroderma
85
Idiopathic interstitial pneumonia
86
Pulmonary arterial hypertension
88
Chronic thromboembolic pulmonary hypertension
210
Single Ventricle
5
Macitentan
(ACT-064992)
[1]
Macitentan
Macitentan
[1]
Macitentan
Macitentan
💬
5.
Macitentan
(ACT-064992)
×
Name
Other Names
Macitentan
Macitentan (JAN/USAN)
Opsumit (TN)
[2]
EDNRA
EDNRA
,
EDNRB
💬
5.
Macitentan
(ACT-064992)
×
Name
Full Name
EDNRA
endothelin receptor type A
EDNRB
endothelin receptor type B
[9]
Calcium signaling pathway
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Relaxin signaling pathway
,
Renin secretion
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
[9]
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in c
...
[1]
86
86
💬
5.
Macitentan
(ACT-064992)
×
Disease ID
Name
86
Pulmonary arterial hypertension
6
Macitentan
10 mg
[1]
Macitentan
Macitentan
[1]
Macitentan
Macitentan
💬
6.
Macitentan
10 mg
×
Name
Other Names
Macitentan
Macitentan (JAN/USAN)
Opsumit (TN)
[2]
EDNRA
EDNRA
,
EDNRB
💬
6.
Macitentan
10 mg
×
Name
Full Name
EDNRA
endothelin receptor type A
EDNRB
endothelin receptor type B
[9]
Calcium signaling pathway
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Relaxin signaling pathway
,
Renin secretion
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
[9]
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in c
...
[3]
51
51
,
86
,
88
💬
6.
Macitentan
10 mg
×
Disease ID
Name
51
Scleroderma
86
Pulmonary arterial hypertension
88
Chronic thromboembolic pulmonary hypertension
7
Macitentan
10 mg tablet, once daily.
[1]
Macitentan
Macitentan
[1]
Macitentan
Macitentan
💬
7.
Macitentan
10 mg tablet, once daily.
×
Name
Other Names
Macitentan
Macitentan (JAN/USAN)
Opsumit (TN)
[2]
EDNRA
EDNRA
,
EDNRB
💬
7.
Macitentan
10 mg tablet, once daily.
×
Name
Full Name
EDNRA
endothelin receptor type A
EDNRB
endothelin receptor type B
[9]
Calcium signaling pathway
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Relaxin signaling pathway
,
Renin secretion
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
[9]
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in c
...
[1]
86
86
💬
7.
Macitentan
10 mg tablet, once daily.
×
Disease ID
Name
86
Pulmonary arterial hypertension
8
Macitentan
10mg
[1]
Macitentan
Macitentan
[1]
Macitentan
Macitentan
💬
8.
Macitentan
10mg
×
Name
Other Names
Macitentan
Macitentan (JAN/USAN)
Opsumit (TN)
[2]
EDNRA
EDNRA
,
EDNRB
💬
8.
Macitentan
10mg
×
Name
Full Name
EDNRA
endothelin receptor type A
EDNRB
endothelin receptor type B
[9]
Calcium signaling pathway
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Relaxin signaling pathway
,
Renin secretion
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
[9]
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in c
...
[2]
51
51
,
88
💬
8.
Macitentan
10mg
×
Disease ID
Name
51
Scleroderma
88
Chronic thromboembolic pulmonary hypertension
9
Macitentan
3 mg
[1]
Macitentan
Macitentan
[1]
Macitentan
Macitentan
💬
9.
Macitentan
3 mg
×
Name
Other Names
Macitentan
Macitentan (JAN/USAN)
Opsumit (TN)
[2]
EDNRA
EDNRA
,
EDNRB
💬
9.
Macitentan
3 mg
×
Name
Full Name
EDNRA
endothelin receptor type A
EDNRB
endothelin receptor type B
[9]
Calcium signaling pathway
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Relaxin signaling pathway
,
Renin secretion
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
[9]
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in c
...
[1]
51
51
💬
9.
Macitentan
3 mg
×
Disease ID
Name
51
Scleroderma
10
Macitentan
37.5 mg
[1]
Macitentan
Macitentan
[1]
Macitentan
Macitentan
💬
10.
Macitentan
37.5 mg
×
Name
Other Names
Macitentan
Macitentan (JAN/USAN)
Opsumit (TN)
[2]
EDNRA
EDNRA
,
EDNRB
💬
10.
Macitentan
37.5 mg
×
Name
Full Name
EDNRA
endothelin receptor type A
EDNRB
endothelin receptor type B
[9]
Calcium signaling pathway
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Relaxin signaling pathway
,
Renin secretion
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
[9]
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in c
...
[1]
86
86
💬
10.
Macitentan
37.5 mg
×
Disease ID
Name
86
Pulmonary arterial hypertension