Drug Description in Trials / DrugBank / KEGG DRUG

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No.

Drug (Description in trials)

DrugBank

KEGG DRUG

KEGG GENES

KEGG PATHWAY

Disease ID

1

[1] Melatonin 💬

[2] MTNR1A,
MTNR1B 💬

[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬

[1] 13 💬

2

[1] Melatonin 💬

[2] MTNR1A,
MTNR1B 💬

[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬

[1] 13 💬

3

Circadin ( INN= Melatonin)

[1] Melatonin 💬

[2] MTNR1A,
MTNR1B 💬

[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬

[1] 13 💬

4

Diazepam, melatonin

[2] Diazepam,
Melatonin

[2] Diazepam ,
Melatonin 💬

[18] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ,
MTNR1A,
MTNR1B 💬

Name	Full Name
GABRA1	gamma-aminobutyric acid type A receptor subunit alpha1
GABRA2	gamma-aminobutyric acid type A receptor subunit alpha2
GABRA3	gamma-aminobutyric acid type A receptor subunit alpha3
GABRA4	gamma-aminobutyric acid type A receptor subunit alpha4
GABRA5	gamma-aminobutyric acid type A receptor subunit alpha5
GABRA6	gamma-aminobutyric acid type A receptor subunit alpha6
GABRB1	gamma-aminobutyric acid type A receptor subunit beta1
GABRB2	gamma-aminobutyric acid type A receptor subunit beta2
GABRB3	gamma-aminobutyric acid type A receptor subunit beta3
GABRD	gamma-aminobutyric acid type A receptor subunit delta
GABRE	gamma-aminobutyric acid type A receptor subunit epsilon
GABRG1	gamma-aminobutyric acid type A receptor subunit gamma1
GABRG2	gamma-aminobutyric acid type A receptor subunit gamma2
GABRG3	gamma-aminobutyric acid type A receptor subunit gamma3
GABRP	gamma-aminobutyric acid type A receptor subunit pi
GABRQ	gamma-aminobutyric acid type A receptor subunit theta
MTNR1A	melatonin receptor 1A
MTNR1B	melatonin receptor 1B

[8] Circadian entrainment, GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬

[1] 46 💬

5

DTR Melatonin (NIH CC PDS)

[1] Melatonin 💬

[2] MTNR1A,
MTNR1B 💬

[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬

[1] 202 💬

6

Extended Release Melatonin

[1] Melatonin 💬

[2] MTNR1A,
MTNR1B 💬

[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬

[1] 6 💬

7

Hourly dosing of the nychtemeral secretion of melatonin

[1] Melatonin 💬

[2] MTNR1A,
MTNR1B 💬

[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬

[1] 202 💬

8

Immediate Release Melatonin

[1] Melatonin 💬

[2] MTNR1A,
MTNR1B 💬

[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬

[1] 6 💬

9

[1] Melatonin 💬

[2] MTNR1A,
MTNR1B 💬

[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬

[12] 6, 8, 13, 37, 46, 49, 72, 78, 90, 97, 145, 202 💬

Disease ID	Name
6	Parkinson disease
8	Huntington disease
13	Multiple sclerosis/Neuromyelitis optica
37	Generalised pustular psoriasis
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
72	Pituitary ADH secretion disorder
78	Hypopituitarism
90	Retinitis pigmentosa
97	Ulcerative colitis
145	West syndrome
202	Smith-Magenis syndrome

10

[1] Melatonin 💬

[2] MTNR1A,
MTNR1B 💬

[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬

[1] 202 💬

11

[1] Melatonin 💬

[2] MTNR1A,
MTNR1B 💬

[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬

[1] 6 💬

12

Melatonin(Circadin®)

[1] Melatonin 💬

[2] MTNR1A,
MTNR1B 💬

[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬

[1] 6 💬