Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1BMS Drug-drug interaction cocktail (montelukast, flurbiprofen, omeprazole, midazolam, and digoxin)[5] Digoxin,
Flurbiprofen,
Midazolam,
Montelukast,
Omeprazole		[5] Digoxin ,
Flurbiprofen ,
Omeprazole ,
Midazolam ,
Montelukast 💬 		[25] ATP1A1,
ATP1A2,
ATP1A3,
ATP1A4,
ATP4A,
ATP4B,
CYSLTR1,
GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ,
PTGS1,
PTGS2 💬 		[49] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Arachidonic acid metabolism, Bile secretion, C-type lectin receptor signaling pathway, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Chemical carcinogenesis - DNA adducts, Collecting duct acid secretion, Endocrine and other factor-regulated calcium reabsorption, GABAergic synapse, Gastric acid secretion, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Insulin secretion, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, Mineral absorption, Morphine addiction, NF-kappa B signaling pathway, Neuroactive ligand-receptor interaction, Nicotine addiction, Ovarian steroidogenesis, Oxidative phosphorylation, Oxytocin signaling pathway, Pancreatic secretion, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Protein digestion and absorption, Proximal tubule bicarbonate reclamation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, Taste transduction, Thyroid hormone signaling pathway, Thyroid hormone synthesis, VEGF signaling pathway, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 46 💬
2Clartihromycin, amoxicillin, and omeprazole[2] Amoxicillin,
Omeprazole		[3] Amoxicillin ,
Omeprazole ,
Amoxicillin 💬 		[2] ATP4A,
ATP4B 💬 		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[1] 6 💬
3Diclofenac + Omeprazole[2] Diclofenac,
Omeprazole		[2] Omeprazole ,
Diclofenac 💬 		[4] ATP4A,
ATP4B,
PTGS1,
PTGS2 💬 		[26] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Collecting duct acid secretion, Gastric acid secretion, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxidative phosphorylation, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 46 💬
4Dimebon + Omeprazole[2] Latrepirdine,
Omeprazole		[2] Omeprazole ,
Latrepirdine 💬 		[8] ACHE,
ATP4A,
ATP4B,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[26] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Dopaminergic synapse, Gastric acid secretion, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Metabolic pathways, Neuroactive ligand-receptor interaction, Nicotine addiction, Oxidative phosphorylation, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8 💬
5Naproxen 500 mg tablets (PN 200 minus omeprazole)[2] Naproxen,
Omeprazole		[2] Naproxen ,
Omeprazole 💬 		[4] ATP4A,
ATP4B,
PTGS1,
PTGS2 💬 		[26] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Collecting duct acid secretion, Gastric acid secretion, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxidative phosphorylation, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[2] 46, 271 💬
6Omeprazol[1] Omeprazole[1] Omeprazole 💬 [2] ATP4A,
ATP4B 💬 		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[1] 294 💬
7Omeprazole[1] Omeprazole[1] Omeprazole 💬 [2] ATP4A,
ATP4B 💬 		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[14] 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
8Omeprazole (UK licensed generic product)[1] Omeprazole[1] Omeprazole 💬 [2] ATP4A,
ATP4B 💬 		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[1] 85 💬
9Omeprazole 20mg[1] Omeprazole[1] Omeprazole 💬 [2] ATP4A,
ATP4B 💬 		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[1] 51 💬
10Omeprazole 40 mg[1] Omeprazole[1] Omeprazole 💬 [2] ATP4A,
ATP4B 💬 		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[1] 96 💬
11Omeprazole 40mg Capsule[1] Omeprazole[1] Omeprazole 💬 [2] ATP4A,
ATP4B 💬 		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[1] 299 💬
12Omeprazole Enteric Capsules[1] Omeprazole[1] Omeprazole 💬 [2] ATP4A,
ATP4B 💬 		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[1] 46 💬
13OMEPRAZOLE MAGNESIUM[2] Magnesium,
Omeprazole		[1] Omeprazole 💬 [2] ATP4A,
ATP4B 💬 		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[1] 225 💬
14Omeprazole rectally 1mg/kg[1] Omeprazole[1] Omeprazole 💬 [2] ATP4A,
ATP4B 💬 		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[1] 294 💬
15PN 200 tablets (500 mg naproxen and 20 mg omeprazole)[2] Naproxen,
Omeprazole		[2] Naproxen ,
Omeprazole 💬 		[4] ATP4A,
ATP4B,
PTGS1,
PTGS2 💬 		[26] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Collecting duct acid secretion, Gastric acid secretion, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxidative phosphorylation, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[2] 46, 271 💬
16Rifaximin+omeprazole+miralax[2] Omeprazole,
Rifaximin		[2] Omeprazole ,
Rifaximin 💬 		[2] ATP4A,
ATP4B 💬 		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[1] 96 💬