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No.
Drug (Description in trials)
DrugBank
KEGG DRUG
KEGG GENES
KEGG PATHWAY
Disease ID
1
Phentermine
[1]
Phentermine
Phentermine
[1]
Phentermine
Phentermine
💬
1.
Phentermine
×
Name
Other Names
Phentermine
Phentermine (USAN/INN)
[5]
MAOA
MAOA
,
MAOB
,
SLC6A2
,
SLC6A3
,
SLC6A4
💬
1.
Phentermine
×
Name
Full Name
MAOA
monoamine oxidase A
MAOB
monoamine oxidase B
SLC6A2
solute carrier family 6 member 2
SLC6A3
solute carrier family 6 member 3
SLC6A4
solute carrier family 6 member 4
[16]
Alcoholism
Alcoholism
,
Amphetamine addiction
,
Arginine and proline metabolism
,
Cocaine addiction
,
Dopaminergic synapse
,
Drug metabolism - cytochrome P450
,
Glycine, serine and threonine metabolism
,
Histidine metabolism
,
Metabolic pathways
,
Parkinson disease
,
Pathways of neurodegeneration - multiple diseases
,
Phenylalanine metabolism
,
Serotonergic synapse
,
Synaptic vesicle cycle
,
Tryptophan metabolism
,
Tyrosine metabolism
💬
[16]
Alcoholism
,
Amphetamine addiction
,
Arginine and proline metabolism
,
Cocaine addiction
,
Dopamine
...
[1]
97
97
💬
1.
Phentermine
×
Disease ID
Name
97
Ulcerative colitis
2
Phentermine
-Topiramate
[2]
Phentermine
Phentermine
,
Topiramate
[2]
Topiramate
Topiramate
,
Phentermine
💬
2.
Phentermine
-Topiramate
×
Name
Other Names
Topiramate
Topiramate (JAN/USP/INN)
Topamax (TN)
Trokendi xr (TN)
EPRONTIA
QUDEXY
Phentermine
Phentermine (USAN/INN)
[41]
CA2
CA2
,
CA4
,
CACNA1C
,
CACNA1D
,
CACNA1F
,
CACNA1S
,
GABRA1
,
GABRA2
,
GABRA3
,
GABRA4
,
GABRA5
,
GABRA6
,
GABRB1
,
GABRB2
,
GABRB3
,
GABRD
,
GABRE
,
GABRG1
,
GABRG2
,
GABRG3
,
GABRP
,
GABRQ
,
GRIA1
,
GRIA2
,
GRIA3
,
GRIA4
,
GRIK1
,
GRIK2
,
GRIK3
,
GRIK4
,
GRIK5
,
MAOA
,
MAOB
,
SCN1A
,
SCN2A
,
SCN3A
,
SCN5A
,
SCN9A
,
SLC6A2
,
SLC6A3
,
SLC6A4
💬
[41]
CA2
,
CA4
,
CACNA1C
,
CACNA1D
,
CACNA1F
,
CACNA1S
,
GABRA1
,
GABRA2
,
GABRA3
,
GABRA4
,
GABRA5
,
GABRA6
,
GABRB1
,
GABRB2
...
2.
Phentermine
-Topiramate
×
Name
Full Name
CA2
carbonic anhydrase 2
CA4
carbonic anhydrase 4
CACNA1C
calcium voltage-gated channel subunit alpha1 C
CACNA1D
calcium voltage-gated channel subunit alpha1 D
CACNA1F
calcium voltage-gated channel subunit alpha1 F
CACNA1S
calcium voltage-gated channel subunit alpha1 S
GABRA1
gamma-aminobutyric acid type A receptor subunit alpha1
GABRA2
gamma-aminobutyric acid type A receptor subunit alpha2
GABRA3
gamma-aminobutyric acid type A receptor subunit alpha3
GABRA4
gamma-aminobutyric acid type A receptor subunit alpha4
GABRA5
gamma-aminobutyric acid type A receptor subunit alpha5
GABRA6
gamma-aminobutyric acid type A receptor subunit alpha6
GABRB1
gamma-aminobutyric acid type A receptor subunit beta1
GABRB2
gamma-aminobutyric acid type A receptor subunit beta2
GABRB3
gamma-aminobutyric acid type A receptor subunit beta3
GABRD
gamma-aminobutyric acid type A receptor subunit delta
GABRE
gamma-aminobutyric acid type A receptor subunit epsilon
GABRG1
gamma-aminobutyric acid type A receptor subunit gamma1
GABRG2
gamma-aminobutyric acid type A receptor subunit gamma2
GABRG3
gamma-aminobutyric acid type A receptor subunit gamma3
GABRP
gamma-aminobutyric acid type A receptor subunit pi
GABRQ
gamma-aminobutyric acid type A receptor subunit theta
GRIA1
glutamate ionotropic receptor AMPA type subunit 1
GRIA2
glutamate ionotropic receptor AMPA type subunit 2
GRIA3
glutamate ionotropic receptor AMPA type subunit 3
GRIA4
glutamate ionotropic receptor AMPA type subunit 4
GRIK1
glutamate ionotropic receptor kainate type subunit 1
GRIK2
glutamate ionotropic receptor kainate type subunit 2
GRIK3
glutamate ionotropic receptor kainate type subunit 3
GRIK4
glutamate ionotropic receptor kainate type subunit 4
GRIK5
glutamate ionotropic receptor kainate type subunit 5
MAOA
monoamine oxidase A
MAOB
monoamine oxidase B
SCN1A
sodium voltage-gated channel alpha subunit 1
SCN2A
sodium voltage-gated channel alpha subunit 2
SCN3A
sodium voltage-gated channel alpha subunit 3
SCN5A
sodium voltage-gated channel alpha subunit 5
SCN9A
sodium voltage-gated channel alpha subunit 9
SLC6A2
solute carrier family 6 member 2
SLC6A3
solute carrier family 6 member 3
SLC6A4
solute carrier family 6 member 4
[63]
Adrenergic signaling in cardiomyocytes
Adrenergic signaling in cardiomyocytes
,
Alcoholism
,
Aldosterone synthesis and secretion
,
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Arginine and proline metabolism
,
Arrhythmogenic right ventricular cardiomyopathy
,
Bile secretion
,
Calcium signaling pathway
,
Carbohydrate digestion and absorption
,
Cardiac muscle contraction
,
Cellular senescence
,
Chemical carcinogenesis - receptor activation
,
Cholinergic synapse
,
Circadian entrainment
,
Cocaine addiction
,
Collecting duct acid secretion
,
Cortisol synthesis and secretion
,
Cushing syndrome
,
Dilated cardiomyopathy
,
Dopaminergic synapse
,
Drug metabolism - cytochrome P450
,
GABAergic synapse
,
Gastric acid secretion
,
Glutamatergic synapse
,
Glycine, serine and threonine metabolism
,
GnRH secretion
,
GnRH signaling pathway
,
Growth hormone synthesis, secretion and action
,
Histidine metabolism
,
Huntington disease
,
Hypertrophic cardiomyopathy
,
Insulin secretion
,
Long-term depression
,
Long-term potentiation
,
MAPK signaling pathway
,
Metabolic pathways
,
Morphine addiction
,
Neuroactive ligand-receptor interaction
,
Nicotine addiction
,
Nitrogen metabolism
,
Oxytocin signaling pathway
,
Pancreatic secretion
,
Parkinson disease
,
Pathways of neurodegeneration - multiple diseases
,
Phenylalanine metabolism
,
Prion disease
,
Proximal tubule bicarbonate reclamation
,
Renin secretion
,
Retrograde endocannabinoid signaling
,
Serotonergic synapse
,
Spinocerebellar ataxia
,
Synaptic vesicle cycle
,
Taste transduction
,
Tight junction
,
Transcriptional misregulation in cancer
,
Tryptophan metabolism
,
Type II diabetes mellitus
,
Tyrosine metabolism
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
[63]
Adrenergic signaling in cardiomyocytes
,
Alcoholism
,
Aldosterone synthesis and secretion
,
Alzhei
...
[1]
97
97
💬
2.
Phentermine
-Topiramate
×
Disease ID
Name
97
Ulcerative colitis