Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
120 mg sildenafil citrate by mouth[1] Sildenafil[1] Sildenafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
25% sildenafil cream[1] Sildenafil[1] Sildenafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 50 💬
3Access program - sildenafil citrate, Viagra, Revatio[1] Sildenafil[1] Sildenafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
4Bosentan and Sildenafil[2] Bosentan,
Sildenafil		[3] Bosentan ,
Bosentan ,
Sildenafil 💬		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
5Duo-Therapy with Sildenafil + Bosentan[2] Bosentan,
Sildenafil		[3] Bosentan ,
Bosentan ,
Sildenafil 💬		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
6ERA and PDE-5I (Sildenafil, Tadalafil, Bosentan, Macitentan)[4] Bosentan,
Macitentan,
Sildenafil,
Tadalafil		[5] Bosentan ,
Tadalafil ,
Bosentan ,
Sildenafil ,
Macitentan 💬		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
7G04BE03- Sildenafil - sildenafil (citrato)[1] Sildenafil[1] Sildenafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
8Mono-Therapy with Sildenafil[1] Sildenafil[1] Sildenafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
9Oral sildenafil[1] Sildenafil[1] Sildenafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
10Sildenafil[1] Sildenafil[1] Sildenafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
11Sildenafil (50 mg)[1] Sildenafil[1] Sildenafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 85 💬
12Sildenafil (Acute-1 hour)[1] Sildenafil[1] Sildenafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 299 💬
13Sildenafil (as citrate)[1] Sildenafil[1] Sildenafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
14Sildenafil (REVATIO)[1] Sildenafil[1] Sildenafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
15Sildenafil (Revatio) 20 mg TID[1] Sildenafil[1] Sildenafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
16Sildenafil (Subchronic-4 weeks)[1] Sildenafil[1] Sildenafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 299 💬
17Sildenafil 20 mg tablets[1] Sildenafil[1] Sildenafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 278 💬
18Sildenafil 20mg[1] Sildenafil[1] Sildenafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[2] 51, 86 💬
19Sildenafil 20mg and Bosentan 62.5mg[2] Bosentan,
Sildenafil		[3] Bosentan ,
Bosentan ,
Sildenafil 💬		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 51, 86 💬
20Sildenafil 40mg oral capsule[1] Sildenafil[1] Sildenafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 299 💬
21Sildenafil and Losartan[2] Losartan,
Sildenafil		[2] Losartan ,
Sildenafil 💬		[2] AGTR1,
PDE5A 💬		[18] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Purine metabolism, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 85 💬
22Sildenafil by injection[1] Sildenafil[1] Sildenafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 210 💬
23Sildenafil citrate[1] Sildenafil[1] Sildenafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[4] 51, 85, 86, 225 💬
24Sildenafil citrate (UK-92,480)[1] Sildenafil[1] Sildenafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
25Sildenafil Filmtabletten[1] Sildenafil[1] Sildenafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
26Sildenafil Oral Suspension[1] Sildenafil[1] Sildenafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 294 💬
27Sildenafil singly or in association with Bosentan[2] Bosentan,
Sildenafil		[3] Bosentan ,
Bosentan ,
Sildenafil 💬		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
28Sildenafil therapy[1] Sildenafil[1] Sildenafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 51 💬
29Sildenafil25 mg----[1] 17 💬
30SILDENAFILO[1] Sildenafil[1] Sildenafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
31Sitaxsentan and Sildenafil[2] Sildenafil,
Sitaxentan		[2] Sitaxentan ,
Sildenafil 💬		[2] EDNRA,
PDE5A 💬		[9] Calcium signaling pathway, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
32Sodium tanshinone IIA sulfonate diluted with 5% glucose solution,20mg sildenafil citrate by mouth[2] Dextrose, unspecified form,
Sildenafil		[1] Sildenafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
33Tadalafil and Sildenafil[2] Sildenafil,
Tadalafil		[2] Tadalafil ,
Sildenafil 💬		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 113 💬