Drug Description in Trials / DrugBank / KEGG DRUG

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Drug (Description in trials)

DrugBank

KEGG DRUG

KEGG GENES

KEGG PATHWAY

Disease ID

1

BG00002 (natalizumab)
(Tysabri (TN))

[1] Natalizumab (Tysabri)

[1] Natalizumab (Tysabri (TN)) 💬

[1] ITGA4 💬

[14] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopath ...

[1] 13 💬

2

BG00002-E (natalizumab high titer)
(Tysabri (TN))

[1] Natalizumab (Tysabri)

[1] Natalizumab (Tysabri (TN)) 💬

[1] ITGA4 💬

[14] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopath ...

[1] 13 💬

3

BG0002 (natalizumab)
(Tysabri (TN))

[1] Natalizumab (Tysabri)

[1] Natalizumab (Tysabri (TN)) 💬

[1] ITGA4 💬

[14] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopath ...

[1] 13 💬

4

Dosing Interruption of Natalizumab
(Tysabri (TN))

[1] Natalizumab (Tysabri)

[1] Natalizumab (Tysabri (TN)) 💬

[1] ITGA4 💬

[14] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopath ...

[1] 13 💬

5

Interferons, glatiramer acetate, teriflunomide, dimethyl fumarate, alemtuzumab, cladribine, fingolim ...

[12] Acetate,
Alemtuzumab,
Cladribine,
Dimethyl fumarate,
Fingolimod,
Glatiramer,
Natalizumab(Tysabri),
Ocr ...

[10] Cladribine ,
Alemtuzumab ,
Rituximab ,
Dimethyl fumarate ,
Ocrelizumab ,
Natalizuma ...

Name	Other Names
Cladribine	Cladribine (JAN/USP/INN) Leustatin (TN) Mavenclad (TN)
Alemtuzumab	Alemtuzumab (USAN/INN) Alemtuzumab (genetical recombination) (JAN) Campath (TN) Lemtrada (TN)
Rituximab	Rituximab (USAN/INN) Rituximab (genetical recombination) (JAN) Rituximab (genetical recombination) [Rituximab biosimilar 1] (JAN) Rituximab (genetical recombination) [Rituximab biosimilar 2] (JAN) Rituximab-abbs Rituximab-pvvr Rituximab-arrx Rituxan (TN) Riabni (TN) Truximab (TN) RUXIENCE TRUXIMA
Dimethyl fumarate	Dimethyl fumarate (JAN/USAN) Tecfidera (TN)
Ocrelizumab	Ocrelizumab (USAN) Ocrelizumab (genetical recombination) (JAN) Ocrevus (TN)
Natalizumab	Natalizumab (USAN/INN) Natalizumab (genetical recombination) (JAN) Tysabri (TN)
Ofatumumab	Ofatumumab (USAN/INN) Ofatumumab (genetical recombination) (JAN) Arzerra (TN) Kesimpta (TN)
Fingolimod	Fingolimod (INN) Gilenya (TN)
Teriflunomide	Teriflunomide (USAN) Aubagio (TN)
Ponesimod	Ponesimod (USAN/INN) Ponvory (TN)

[7] CD52,
DHODH,
ITGA4,
KEAP1,
MS4A1,
RRM1,
S1PR1 💬

Name	Full Name
CD52	CD52 molecule
DHODH	dihydroorotate dehydrogenase (quinone)
ITGA4	integrin subunit alpha 4
KEAP1	kelch like ECH associated protein 1
MS4A1	membrane spanning 4-domains A1
RRM1	ribonucleotide reductase catalytic subunit M1
S1PR1	sphingosine-1-phosphate receptor 1

[30] Arrhythmogenic right ventricular cardiomyopathy, Biosynthesis of cofactors, Cell adhesion molec ...

[1] 13 💬

6

NATALIZUMAB
(Tysabri (TN))

[1] Natalizumab (Tysabri)

[1] Natalizumab (Tysabri (TN)) 💬

[1] ITGA4 💬

[14] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopath ...

[5] 13, 15, 25, 46, 96 💬

7

Natalizumab (BG00002)
(Tysabri (TN))

[1] Natalizumab (Tysabri)

[1] Natalizumab (Tysabri (TN)) 💬

[1] ITGA4 💬

[14] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopath ...

[1] 13 💬

8

Natalizumab (NTZ)
(Tysabri (TN))

[1] Natalizumab (Tysabri)

[1] Natalizumab (Tysabri (TN)) 💬

[1] ITGA4 💬

[14] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopath ...

[1] 13 💬

9

Natalizumab (Tysabri)

[1] Natalizumab (Tysabri)

[1] Natalizumab (Tysabri (TN)) 💬

[1] ITGA4 💬

[14] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopath ...

[1] 13 💬

10

Natalizumab 300 MG in 15 ML Injection
(Tysabri (TN))

[1] Natalizumab (Tysabri)

[1] Natalizumab (Tysabri (TN)) 💬

[1] ITGA4 💬

[14] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopath ...

[1] 13 💬

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