Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1ERA and PDE-5I (Sildenafil, Tadalafil, Bosentan, Macitentan)[4] Bosentan,
Macitentan,
Sildenafil,
Tadalafil		[5] Bosentan ,
Tadalafil ,
Bosentan ,
Sildenafil ,
Macitentan 💬		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
2FDC macitentan/tadalafil[2] Macitentan,
Tadalafil		[2] Tadalafil ,
Macitentan 💬		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
3Tadalafil[1] Tadalafil[1] Tadalafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[7] 6, 51, 75, 84, 86, 113, 210 💬
4Tadalafil 20 MG[1] Tadalafil[1] Tadalafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 113 💬
5Tadalafil 20 mg film-coated tablets[1] Tadalafil[1] Tadalafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
6Tadalafil 40 mg[1] Tadalafil[1] Tadalafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
7Tadalafil and ambrisentan upfront combination therapy[2] Ambrisentan,
Tadalafil		[2] Tadalafil ,
Ambrisentan 💬		[2] EDNRA,
PDE5A 💬		[9] Calcium signaling pathway, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 51, 86 💬
8Tadalafil and Sildenafil[2] Sildenafil,
Tadalafil		[2] Tadalafil ,
Sildenafil 💬		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 113 💬
9Tadalafil Citrate[1] Tadalafil[1] Tadalafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 210 💬
10Tadalafil oral suspension[1] Tadalafil[1] Tadalafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
11Tadalafil- Tablet or Oral suspension[1] Tadalafil[1] Tadalafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
12TADALAFILO[1] Tadalafil[1] Tadalafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬