Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1Bosentan
(Tracleer, TRACLEER)		[1] Bosentan[2] Bosentan (Tracleer, TRACLEER),
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[11] 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
2Bosentan 125 MG
(Tracleer, TRACLEER)		[1] Bosentan[2] Bosentan (Tracleer, TRACLEER),
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 51 💬
3Bosentan 62.5 MG
(Tracleer, TRACLEER)		[1] Bosentan[2] Bosentan (Tracleer, TRACLEER),
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 51 💬
4Bosentan administration
(Tracleer, TRACLEER)		[1] Bosentan[2] Bosentan (Tracleer, TRACLEER),
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
5Bosentan dispersible tablets
(Tracleer, TRACLEER)		[1] Bosentan[2] Bosentan (Tracleer, TRACLEER),
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
6Bosentan group
(Tracleer, TRACLEER)		[1] Bosentan[2] Bosentan (Tracleer, TRACLEER),
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 51 💬
7Bosentan monohydrat
(Tracleer, TRACLEER)		[1] Bosentan[2] Bosentan (Tracleer, TRACLEER),
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
8Bosentan monohydrate
(Tracleer, TRACLEER)		[1] Bosentan[2] Bosentan (Tracleer, TRACLEER),
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 51, 84, 86, 88 💬
9Bosentan mylan
(Tracleer, TRACLEER)		[1] Bosentan[2] Bosentan (Tracleer, TRACLEER),
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 41 💬
10Bosentan, ambrisentan
(Tracleer, TRACLEER)		[1] Bosentan[2] Bosentan (Tracleer, TRACLEER),
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
11DUO-therapy with sildenafil + bosentan
(Tracleer, TRACLEER)		----[1] 86 💬
12Observational study with patients treated with tracleer, ventavis, veletri, opsumit and/or uptravi----[1] 86 💬
13Sildenafil 20MG and bosentan 62.5MG
(Tracleer, TRACLEER)		[1] Sildenafil[2] Sildenafil citrate ,
Sildenafil 💬 		[1] PDE5 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[2] 51, 86 💬
14Sildenafil singly or IN association with bosentan
(Tracleer, TRACLEER)		[1] Sildenafil[2] Sildenafil citrate ,
Sildenafil 💬 		[1] PDE5 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
15Tracleer[1] Bosentan[2] Bosentan (Tracleer, TRACLEER),
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 13, 51, 84, 85, 86, 88, 210, 211 💬
16Tracleer tablet FOR oral suspension[1] Bosentan[2] Bosentan (Tracleer, TRACLEER),
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
17Tracleer*56CPR RIV 125MG[1] Bosentan[2] Bosentan (Tracleer, TRACLEER),
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 51, 86, 88 💬