KEGG DRUG

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Drug (Description in trials)

DrugBank

KEGG DRUG

KEGG GENES

KEGG PATHWAY

Disease ID

Dextromethorphan
(D03742)

[1] Dextromethorphan

[1] Dextromethorphan (D03742) 💬

[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬

Name	Full Name
GRIN1	glutamate ionotropic receptor NMDA type subunit 1
GRIN2A	glutamate ionotropic receptor NMDA type subunit 2A
GRIN2B	glutamate ionotropic receptor NMDA type subunit 2B
GRIN2C	glutamate ionotropic receptor NMDA type subunit 2C
GRIN2D	glutamate ionotropic receptor NMDA type subunit 2D
SIGMAR1	sigma non-opioid intracellular receptor 1

[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium si ...

[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
6	Parkinson disease
8	Huntington disease
13	Multiple sclerosis/Neuromyelitis optica
21	Mitochondrial disease
46	Malignant rheumatoid arthritis
78	Hypopituitarism
85	Idiopathic interstitial pneumonia
96	Crohn disease
97	Ulcerative colitis
156	Rett syndrome

Dextromethorphan and Caffeine
(D03742)

[2] Caffeine,
Dextromethorphan

[3] Caffeine ,
Caffeine hydrate ,
Dextromethorphan (D03742) 💬

Name	Other Names
Caffeine	Caffeine (USP) Anhydrous caffeine (JP18) Anhydrous caffeine (TN) Respia (TN)
Caffeine hydrate	Caffeine hydrate (JP18) Caffeine monohydrate Caffeine (TN)
Dextromethorphan	Dextromethorphan (USP)

[17] ADORA1,
ADORA2A,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4 ...

Name	Full Name
ADORA1	adenosine A1 receptor
ADORA2A	adenosine A2a receptor
GRIN1	glutamate ionotropic receptor NMDA type subunit 1
GRIN2A	glutamate ionotropic receptor NMDA type subunit 2A
GRIN2B	glutamate ionotropic receptor NMDA type subunit 2B
GRIN2C	glutamate ionotropic receptor NMDA type subunit 2C
GRIN2D	glutamate ionotropic receptor NMDA type subunit 2D
PDE1B	phosphodiesterase 1B
PDE2A	phosphodiesterase 2A
PDE3A	phosphodiesterase 3A
PDE3B	phosphodiesterase 3B
PDE4A	phosphodiesterase 4A
PDE4B	phosphodiesterase 4B
PDE4C	phosphodiesterase 4C
PDE4D	phosphodiesterase 4D
PDE5A	phosphodiesterase 5A
SIGMAR1	sigma non-opioid intracellular receptor 1

[37] Alcoholism, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyo ...

[1] 78 💬

Dextromethorphan HBr and quinidine sulfate
(D03742)

[3] Dextromethorphan,
Quinidine,
Sulfate ion

[2] Dextromethorphan (D03742),
Quinidine 💬

[11] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A,
SIGMAR1 💬

Name	Full Name
GRIN1	glutamate ionotropic receptor NMDA type subunit 1
GRIN2A	glutamate ionotropic receptor NMDA type subunit 2A
GRIN2B	glutamate ionotropic receptor NMDA type subunit 2B
GRIN2C	glutamate ionotropic receptor NMDA type subunit 2C
GRIN2D	glutamate ionotropic receptor NMDA type subunit 2D
SCN1A	sodium voltage-gated channel alpha subunit 1
SCN2A	sodium voltage-gated channel alpha subunit 2
SCN3A	sodium voltage-gated channel alpha subunit 3
SCN5A	sodium voltage-gated channel alpha subunit 5
SCN9A	sodium voltage-gated channel alpha subunit 9
SIGMAR1	sigma non-opioid intracellular receptor 1

[22] Adrenergic signaling in cardiomyocytes, Alcoholism, Alzheimer disease, Amphetamine addiction, A ...

[1] 2 💬

DEXTROMETHORPHAN HYDROBROMIDE
(D03742)

[1] Dextromethorphan

[1] Dextromethorphan (D03742) 💬

[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬

Name	Full Name
GRIN1	glutamate ionotropic receptor NMDA type subunit 1
GRIN2A	glutamate ionotropic receptor NMDA type subunit 2A
GRIN2B	glutamate ionotropic receptor NMDA type subunit 2B
GRIN2C	glutamate ionotropic receptor NMDA type subunit 2C
GRIN2D	glutamate ionotropic receptor NMDA type subunit 2D
SIGMAR1	sigma non-opioid intracellular receptor 1

[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium si ...

[2] 13, 46 💬

Dextromethorphan hydrobromide 20 mg and quinidine sulfate 10 mg
(D03742)

[3] Dextromethorphan,
Quinidine,
Sulfate ion

[2] Dextromethorphan (D03742),
Quinidine 💬

[11] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A,
SIGMAR1 💬

Name	Full Name
GRIN1	glutamate ionotropic receptor NMDA type subunit 1
GRIN2A	glutamate ionotropic receptor NMDA type subunit 2A
GRIN2B	glutamate ionotropic receptor NMDA type subunit 2B
GRIN2C	glutamate ionotropic receptor NMDA type subunit 2C
GRIN2D	glutamate ionotropic receptor NMDA type subunit 2D
SCN1A	sodium voltage-gated channel alpha subunit 1
SCN2A	sodium voltage-gated channel alpha subunit 2
SCN3A	sodium voltage-gated channel alpha subunit 3
SCN5A	sodium voltage-gated channel alpha subunit 5
SCN9A	sodium voltage-gated channel alpha subunit 9
SIGMAR1	sigma non-opioid intracellular receptor 1

[22] Adrenergic signaling in cardiomyocytes, Alcoholism, Alzheimer disease, Amphetamine addiction, A ...

[2] 2, 13 💬

Dextromethorphan hydrobromide 30 mg and quinidine sulfate 10 mg
(D03742)

[3] Dextromethorphan,
Quinidine,
Sulfate ion

[2] Dextromethorphan (D03742),
Quinidine 💬

[11] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A,
SIGMAR1 💬

Name	Full Name
GRIN1	glutamate ionotropic receptor NMDA type subunit 1
GRIN2A	glutamate ionotropic receptor NMDA type subunit 2A
GRIN2B	glutamate ionotropic receptor NMDA type subunit 2B
GRIN2C	glutamate ionotropic receptor NMDA type subunit 2C
GRIN2D	glutamate ionotropic receptor NMDA type subunit 2D
SCN1A	sodium voltage-gated channel alpha subunit 1
SCN2A	sodium voltage-gated channel alpha subunit 2
SCN3A	sodium voltage-gated channel alpha subunit 3
SCN5A	sodium voltage-gated channel alpha subunit 5
SCN9A	sodium voltage-gated channel alpha subunit 9
SIGMAR1	sigma non-opioid intracellular receptor 1

[22] Adrenergic signaling in cardiomyocytes, Alcoholism, Alzheimer disease, Amphetamine addiction, A ...

[2] 2, 13 💬

Dextromethorphan/Quinidine
(D03742)

[2] Dextromethorphan,
Quinidine

[2] Dextromethorphan (D03742),
Quinidine 💬

[11] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A,
SIGMAR1 💬

Name	Full Name
GRIN1	glutamate ionotropic receptor NMDA type subunit 1
GRIN2A	glutamate ionotropic receptor NMDA type subunit 2A
GRIN2B	glutamate ionotropic receptor NMDA type subunit 2B
GRIN2C	glutamate ionotropic receptor NMDA type subunit 2C
GRIN2D	glutamate ionotropic receptor NMDA type subunit 2D
SCN1A	sodium voltage-gated channel alpha subunit 1
SCN2A	sodium voltage-gated channel alpha subunit 2
SCN3A	sodium voltage-gated channel alpha subunit 3
SCN5A	sodium voltage-gated channel alpha subunit 5
SCN9A	sodium voltage-gated channel alpha subunit 9
SIGMAR1	sigma non-opioid intracellular receptor 1

[22] Adrenergic signaling in cardiomyocytes, Alcoholism, Alzheimer disease, Amphetamine addiction, A ...

[1] 13 💬

Dextromethorphan/quinidine 20mg/10mg (DM/Q 20mg/10mg)
(D03742)

[2] Dextromethorphan,
Quinidine

[2] Dextromethorphan (D03742),
Quinidine 💬

[11] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A,
SIGMAR1 💬

Name	Full Name
GRIN1	glutamate ionotropic receptor NMDA type subunit 1
GRIN2A	glutamate ionotropic receptor NMDA type subunit 2A
GRIN2B	glutamate ionotropic receptor NMDA type subunit 2B
GRIN2C	glutamate ionotropic receptor NMDA type subunit 2C
GRIN2D	glutamate ionotropic receptor NMDA type subunit 2D
SCN1A	sodium voltage-gated channel alpha subunit 1
SCN2A	sodium voltage-gated channel alpha subunit 2
SCN3A	sodium voltage-gated channel alpha subunit 3
SCN5A	sodium voltage-gated channel alpha subunit 5
SCN9A	sodium voltage-gated channel alpha subunit 9
SIGMAR1	sigma non-opioid intracellular receptor 1

[22] Adrenergic signaling in cardiomyocytes, Alcoholism, Alzheimer disease, Amphetamine addiction, A ...

[1] 8 💬

Dimebon + Dextromethorphan
(D03742)

[2] Dextromethorphan,
Latrepirdine

[2] Dextromethorphan (D03742),
Latrepirdine 💬

[7] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬

Name	Full Name
ACHE	acetylcholinesterase (Cartwright blood group)
GRIN1	glutamate ionotropic receptor NMDA type subunit 1
GRIN2A	glutamate ionotropic receptor NMDA type subunit 2A
GRIN2B	glutamate ionotropic receptor NMDA type subunit 2B
GRIN2C	glutamate ionotropic receptor NMDA type subunit 2C
GRIN2D	glutamate ionotropic receptor NMDA type subunit 2D
SIGMAR1	sigma non-opioid intracellular receptor 1

[22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium si ...

[1] 8 💬

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