Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Acetylcysteine [3] Acetylcysteine; Mucomyst; N-acetylcysteine[1] Acetylcysteine 💬--[21] 6, 13, 19, 20, 21, 49, 51, 53, 58, 63, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337 💬
2 Bupropion [2] Bupropion; Bupropion Hydrochloride[1] Bupropion 💬[2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[5] 8, 18, 21, 96, 171 💬
3 Caffeine [1] Caffeine[2] Caffeine ,
Caffeine hydrate 💬		[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 21, 46, 78, 96, 97, 265 💬
4 Cariprazine [1] Reagila[1] Cariprazine 💬[3] DRD2,
HTR1A,
HTR2A 💬		[12] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[1] 21 💬
5 Cysteamine [8] 2-aminoethanethiol; Beta-Mercaptoethylamine; CYSTADROPS; CYSTAGON; CYSTEAMINE; Mercaptamina; Mercaptamine; PROCYSBI[1] Cysteamine 💬--[4] 8, 19, 21, 299 💬
6 Dexmedetomidine [4] Dexdor; DEXMEDETOMIDINA; Dexmedetomidine; DEXMEDETOMIDINE HYDROCHLORIDE[1] Dexmedetomidine 💬[3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[14] 2, 4, 6, 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
7 Dextromethorphan [4] Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta[1] Dextromethorphan 💬[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156 💬
8 Elamipretide [1] ELAMIPRETIDE[1] Elamipretide 💬--[2] 21, 324 💬
9 Flurbiprofen [1] Flurbiprofen[1] Flurbiprofen 💬[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[3] 13, 21, 46 💬
10 Haemagglutinin-strain B [2] Fluzone; Influvac---[4] 21, 46, 49, 50 💬
11 Influenza A virus A/Brisbane/59/2007 (H1N1) antigen (formaldehyde inactivated) [1] Fluzone---[2] 21, 49 💬
12 Influenza A virus A/California/7/2009 X-179A (H1N1) antigen (formaldehyde inactivated) [1] Fluzone---[2] 21, 49 💬
13 Influenza A virus A/Switzerland/9715293/2013 NIB-88 (H3N2) antigen (formaldehyde inactivated) [1] Fluzone---[2] 21, 49 💬
14 Influenza A virus A/Texas/50/2012 X-223A (H3N2) antigen (formaldehyde inactivated) [1] Fluzone---[2] 21, 49 💬
15 Influenza A virus A/Uruguay/716/2007(H3N2) antigen (formaldehyde inactivated) [1] Fluzone---[2] 21, 49 💬
16 Influenza A virus A/Victoria/210/2009 X-187 (H3N2) antigen (formaldehyde inactivated) [1] Fluzone---[2] 21, 49 💬
17 Influenza A virus A/Victoria/361/2011 IVR-165 (H3N2) antigen (formaldehyde inactivated) [1] Fluzone---[2] 21, 49 💬
18 Influenza B virus B/Brisbane/60/2008 antigen (formaldehyde inactivated) [1] Fluzone---[2] 21, 49 💬
19 Influenza B virus B/Massachusetts/2/2012 antigen (formaldehyde inactivated) [1] Fluzone---[2] 21, 49 💬
20 Influenza B virus B/Massachusetts/2/2012 BX-51B antigen (formaldehyde inactivated) [1] Fluzone---[2] 21, 49 💬
21 Influenza B virus B/Phuket/3073/2013 antigen (formaldehyde inactivated) [1] Fluzone---[2] 21, 49 💬
22 Influenza B virus B/Texas/6/2011 antigen (formaldehyde inactivated) [1] Fluzone---[2] 21, 49 💬
23 Midazolam [2] Midazolam; Midazolam injection[1] Midazolam 💬[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
24 Omeprazole [4] Losec; Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM[1] Omeprazole 💬[2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[14] 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
25 Phenylbutyric acid [4] 4-phenylbutyrate; Pheburane; Phenylbutyrate; Sodium Phenylbutyrate---[14] 2, 3, 6, 8, 15, 21, 93, 94, 231, 244, 251, 297, 299, 338 💬
26 Propofol [2] Propofol; Propofol Injection[1] Propofol 💬[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[9] 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
27 Repaglinide [1] Repaglinide[1] Repaglinide 💬[2] ABCC8,
KCNJ11 💬		[4] ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬[4] 6, 21, 46, 299 💬
28 Sevoflurane [1] Sevoflurane[1] Sevoflurane 💬--[7] 6, 21, 22, 34, 98, 225, 296 💬
29 Sonlicromanol [1] Sonlicromanol---[1] 21 💬
30 Tocotrienol [1] Tocotrienol---[3] 21, 156, 299 💬
31 Uridine triacetate [1] Tri-O-acetyluridine[1] Uridine triacetate 💬--[1] 21 💬
32 Vatiquinone [1] VATIQUINONE[1] Vatiquinone 💬--[2] 18, 21 💬