KEGG DRUG

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DrugBank

Drug (Description in trials)

KEGG DRUG

KEGG GENES

KEGG PATHWAY

Disease ID

Dalfampridine

[7] 4-Aminopyridine; 4-AP; AMPYRA; Dalfampridine; FAMPRIDINA; FAMPRIDINE; FAMPYRA

[1] Dalfampridine 💬

[4] KCNA4,
KCNC3,
KCND2,
KCND3 💬

Name	Full Name
KCNA4	potassium voltage-gated channel subfamily A member 4
KCNC3	potassium voltage-gated channel subfamily C member 3
KCND2	potassium voltage-gated channel subfamily D member 2
KCND3	potassium voltage-gated channel subfamily D member 3

[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia ...

[5] 3, 4, 6, 13, 14 💬

Dexmedetomidine

[4] Dexdor; DEXMEDETOMIDINA; Dexmedetomidine; DEXMEDETOMIDINE HYDROCHLORIDE

[1] Dexmedetomidine 💬

[3] ADRA2A,
ADRA2B,
ADRA2C 💬

[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬

[14] 2, 4, 6, 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
4	Primary lateral sclerosis
6	Parkinson disease
21	Mitochondrial disease
34	Neurofibromatosis
46	Malignant rheumatoid arthritis
70	Spinal stenosis
107	Juvenile idiopathic arthritis
113	Muscular dystrophy
171	Wilson disease
212	Tricuspid atresia
215	Tetralogy of Fallot
226	Interstitial cystitis with Hunners ulcer
280	Huge arteriovenous malformation with cervicofacial or limb lesion

Esketamine

[3] ESKETAMINE; KETAMINE; S-ketamine

[1] Esketamine 💬

[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬

Name	Full Name
GRIN1	glutamate ionotropic receptor NMDA type subunit 1
GRIN2A	glutamate ionotropic receptor NMDA type subunit 2A
GRIN2B	glutamate ionotropic receptor NMDA type subunit 2B
GRIN2C	glutamate ionotropic receptor NMDA type subunit 2C
GRIN2D	glutamate ionotropic receptor NMDA type subunit 2D

[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium si ...

[3] 2, 4, 70 💬

Ketamine

[2] Ketamine; NMDA

[1] Ketamine 💬

[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬

Name	Full Name
GRIN1	glutamate ionotropic receptor NMDA type subunit 1
GRIN2A	glutamate ionotropic receptor NMDA type subunit 2A
GRIN2B	glutamate ionotropic receptor NMDA type subunit 2B
GRIN2C	glutamate ionotropic receptor NMDA type subunit 2C
GRIN2D	glutamate ionotropic receptor NMDA type subunit 2D

[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium si ...

[8] 2, 4, 6, 13, 70, 113, 156, 215 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
4	Primary lateral sclerosis
6	Parkinson disease
13	Multiple sclerosis/Neuromyelitis optica
70	Spinal stenosis
113	Muscular dystrophy
156	Rett syndrome
215	Tetralogy of Fallot

Levetiracetam

[2] KEPPRA; Levetiracetam

[1] Levetiracetam 💬

[1] SV2A 💬

[1] ECM-receptor interaction 💬

[5] 2, 4, 6, 13, 307 💬

Pyrimethamine

[2] Daraprim; PYRIMETHAMINE

[1] Pyrimethamine 💬

[12] 2, 4, 6, 13, 19, 46, 51, 63, 65, 96, 97, 265 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
4	Primary lateral sclerosis
6	Parkinson disease
13	Multiple sclerosis/Neuromyelitis optica
19	Lysosomal storage disease
46	Malignant rheumatoid arthritis
51	Scleroderma
63	Idiopathic thrombocytopenic purpura
65	Primary immunodeficiency
96	Crohn disease
97	Ulcerative colitis
265	Lipodystrophy

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