Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Acetylcysteine [3] Acetylcysteine; Mucomyst; N-acetylcysteine[1] Acetylcysteine 💬--[21] 6, 13, 19, 20, 21, 49, 51, 53, 58, 63, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337 💬
2 Alemtuzumab [4] Alemtuzumab; Campath; Lemtrada; MABCAMPATH[1] Alemtuzumab 💬[1] CD52 💬-[22] 13, 15, 19, 20, 36, 43, 44, 46, 49, 51, 60, 62, 63, 65, 85, 96, 164, 234, 283, 284, 285, 326 💬
3 Aminophylline [1] Aminophylline[1] Aminophylline 💬[18] ADORA1,
ADORA2B,
PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬		[23] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 63 💬
4 Amoxicillin [4] Amoxicilina; Amoxicillin; Amoxycillin; Augmentin[2] Amoxicillin ,
Amoxicillin 💬		--[9] 6, 19, 46, 63, 84, 96, 97, 222, 299 💬
5 Atorvastatin [3] Atorvastatin; Atorvastatin calcium; Lipitor[1] Atorvastatin 💬[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[19] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
6 Avatrombopag [2] Avatrombopag; Doptelet[1] Avatrombopag 💬[1] MPL 💬[2] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬[2] 60, 63 💬
7 Azathioprine [3] Azathioprine; Azatioprina; Imuran[1] Azathioprine 💬--[21] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162 💬
8 Belimumab [2] BELIMUMAB; BENLYSTA[1] Belimumab 💬[1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[13] 11, 13, 43, 44, 46, 49, 51, 53, 63, 66, 222, 296, 300 💬
9 Bevifimod [1] STAPHYLOCOCCAL PROTEIN A---[1] 63 💬
10 Blisibimod [1] Blisibimod[1] Blisibimod 💬--[5] 43, 44, 49, 63, 66 💬
11 Bortezomib [3] Bortezomib; Bortezomib Accord; Velcade[1] Bortezomib 💬[1] PSMB5 💬[8] Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬[17] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬
12 Clarithromycin [1] Clarithromycin[1] Clarithromycin 💬--[8] 6, 63, 84, 96, 97, 222, 228, 299 💬
13 Cyclosporine [10] Ciclosporin; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; Neoral; RESTASIS[1] Cyclosporine 💬[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
14 Danazol [1] Danazol[1] Danazol 💬[3] AR,
ESR1,
PGR 💬		[12] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[5] 60, 63, 64, 65, 285 💬
15 Daratumumab [2] DARATUMUMAB; Darzalex[1] Daratumumab 💬[1] CD38 💬[7] Calcium signaling pathway, Hematopoietic cell lineage, Metabolic pathways, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬[5] 13, 28, 48, 49, 63 💬
16 Decitabine [1] Decitabine[1] Decitabine 💬[3] DNMT1,
DNMT3A,
DNMT3B 💬		[3] Cysteine and methionine metabolism, Metabolic pathways, MicroRNAs in cancer 💬[3] 13, 60, 63 💬
17 Dexamethasone [5] Decadron; Dexametasona; Dexamethasone; Dexamethasone sodium phosphate; Maxidex[1] Dexamethasone 💬[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[22] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
18 Diacerein [1] Diacerein[1] Diacerein 💬--[3] 36, 46, 63 💬
19 Efgartigimod alfa [1] Efgartigimod alfa[1] Efgartigimod alfa 💬[1] FCGRT 💬-[6] 11, 14, 35, 53, 63, 162 💬
20 Eltrombopag [3] Eltrombopag; Promacta; REVOLADE---[5] 60, 63, 65, 284, 285 💬
21 GMA-161 [0] ---[1] 63 💬
22 Gold [1] Gold---[43] 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 63, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 167, 171, 193, 218, 222, 224, 226, 227, 230, 271, 291, 296, 298, 310, 318 💬
23 Hetrombopag [1] Hetrombopag---[2] 60, 63 💬
24 Human immunoglobulin G [19] Bivigam; CUTAQUIG; CUVITRU; GAMMAGARD LIQUID; Gammaplex; GAMUNEX-C; Hizentra; Human Immunoglobulin G; Human normal immunoglobulin; HyQvia; Immune globulin; Immunoglobulin; IMMUNOGLOBULIN G; IVIg; KIOVIG; Octagam; PANZYGA; Privigen; Vivaglobin---[10] 11, 13, 14, 17, 43, 45, 50, 51, 63, 65 💬
25 Human interleukin-2 [3] Human interleukin-2; IL-2; INTERLEUKIN-2---[18] 2, 13, 35, 46, 49, 50, 51, 53, 55, 56, 60, 63, 65, 95, 96, 97, 162, 271 💬
26 Hydroxychloroquine [3] Hydroxychloroquine; Hydroxychloroquine sulfate; PLAQUENIL[1] Hydroxychloroquine 💬--[27] 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299 💬
27 Ianalumab [1] Ianalumab[1] Ianalumab 💬[1] TNFRSF13C 💬[5] Cytokine-cytokine receptor interaction, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Primary immunodeficiency 💬[7] 35, 46, 49, 53, 61, 63, 95 💬
28 Lansoprazole [1] Lansoprazole[1] Lansoprazole 💬[2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[7] 63, 71, 85, 98, 166, 222, 299 💬
29 Magnesium [1] Magnesium---[19] 6, 11, 13, 46, 51, 63, 64, 70, 93, 97, 111, 166, 225, 235, 284, 291, 296, 297, 298 💬
30 Methylprednisolone [4] Medrol; Methylprednisolon; Methylprednisolone; Methylprednisolone acetate[1] Methylprednisolone 💬[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[46] 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
31 Metronidazole [3] Flagyl; Metronidazol; METRONIDAZOLE[1] Metronidazole 💬--[7] 46, 51, 63, 94, 96, 97, 291 💬
32 Mezagitamab [1] Mezagitamab[1] Mezagitamab 💬[1] CD38 💬[7] Calcium signaling pathway, Hematopoietic cell lineage, Metabolic pathways, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬[2] 63, 66 💬
33 Montelukast [3] Montelukast; MONTELUKAST SODIUM; Singulair[1] Montelukast 💬[1] CYSLTR1 💬[2] Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬[8] 6, 13, 46, 61, 63, 85, 98, 228 💬
34 Natalizumab [2] Natalizumab; TYSABRI[1] Natalizumab 💬[1] ITGA4 💬[14] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Yersinia infection 💬[6] 13, 15, 25, 46, 63, 96 💬
35 Orelabrutinib [1] Orelabrutinib[1] Orelabrutinib 💬[1] BTK 💬[7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[4] 13, 49, 61, 63 💬
36 Palmitic Acid [1] Palmitate[1] Palmitic acid 💬--[1] 63 💬
37 Prednisolone [3] Prednisolona; Prednisolone; Prednisolonum[1] Prednisolone 💬[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[42] 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
38 Prednisone [3] Prednisona; Prednisone; RAYOS[1] Prednisone 💬[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[45] 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬
39 Pyrimethamine [2] Daraprim; PYRIMETHAMINE[1] Pyrimethamine 💬--[12] 2, 4, 6, 13, 19, 46, 51, 63, 65, 96, 97, 265 💬
40 Recombinant Human Thrombopoietin [2] Recombinant Human Thrombopoietin; RhTPO---[2] 60, 63 💬
41 Rituximab [6] MabThera; Rituxan; RITUXIMAB; Rixathon; Ruxience; Truxima[1] Rituximab 💬[1] MS4A1 💬[1] Hematopoietic cell lineage 💬[48] 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
42 Romiplostim [2] NPLATE; Romiplostim[1] Romiplostim 💬[1] MPL 💬[2] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬[4] 60, 63, 64, 65 💬
43 Rozanolixizumab [1] ROZANOLIXIZUMAB[1] Rozanolixizumab 💬[1] FCGRT 💬-[3] 11, 14, 63 💬
44 Sirolimus [3] Rapamune; Rapamycin; Sirolimus[1] Sirolimus 💬[1] MTOR 💬[51] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[40] 2, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
45 Thrombopoietin [1] Thrombopoietin---[3] 47, 60, 63 💬
46 Toralizumab [1] Anti-CD40L[1] Toralizumab 💬[1] CD40LG 💬[14] Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, Lipid and atherosclerosis, Malaria, NF-kappa B signaling pathway, Primary immunodeficiency, Systemic lupus erythematosus, T cell receptor signaling pathway, Toxoplasmosis, Viral myocarditis 💬[1] 63 💬
47 Tretinoin [5] ATRA; Retinoic acid; Tretinoin; TRETINOINA; VESANOID[1] Tretinoin 💬[3] PML,
RARA,
RARB 💬		[12] Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬[6] 2, 62, 63, 75, 94, 231 💬
48 Vonoprazan [1] Vonoprazan[1] Vonoprazan 💬[2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[2] 63, 98 💬
49 Water [8] AVONEX; ENBREL; Hiberix; Indocyanine green; OMNITROPE; Sterile Water for Injection; Water; WATER FOR INJECTION[1] Water 💬--[21] 2, 5, 6, 13, 17, 22, 35, 46, 53, 57, 63, 65, 67, 78, 84, 96, 97, 206, 226, 278, 299 💬
50 Zanubrutinib [1] Zanubrutinib[1] Zanubrutinib 💬[1] BTK 💬[7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[5] 13, 63, 222, 300, 331 💬