KEGG DRUG

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No.

DrugBank

Drug (Description in trials)

KEGG DRUG

KEGG GENES

KEGG PATHWAY

Disease ID

Ammonium chloride

[1] Ammonium chloride

[1] Ammonium chloride 💬

[3] 96, 107, 251 💬

Atropine
(ATNAA atropine and pralidoxime chloride Auto-Injector)

[2] Atropina; Atropine

[1] Atropine 💬

[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬

Name	Full Name
CHRM1	cholinergic receptor muscarinic 1
CHRM2	cholinergic receptor muscarinic 2
CHRM3	cholinergic receptor muscarinic 3
CHRM4	cholinergic receptor muscarinic 4
CHRM5	cholinergic receptor muscarinic 5

[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬

[2] 2, 299 💬

Bethanechol
(PMS-bethanechol Chloride Tab 50mg)

[1] Bethanechol

[1] 98 💬

Calcium
(Magnesium Chloride)

[2] Calcio; Calcium

[27] 6, 13, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 156, 214, 215, 222, 224, 235, 265, 274, 298, 299 💬

Disease ID	Name
6	Parkinson disease
13	Multiple sclerosis/Neuromyelitis optica
19	Lysosomal storage disease
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
51	Scleroderma
53	Sjogren syndrome
56	Behcet disease
68	Ossification of the ligamentum flavum
75	Cushing disease
79	Homozygous familial hypercholesterolemia
84	Sarcoidosis
93	Primary biliary cholangitis
94	Primary sclerosing cholangitis
95	Autoimmune hepatitis
96	Crohn disease
97	Ulcerative colitis
156	Rett syndrome
214	Pulmonary atresia with ventricular septum defect
215	Tetralogy of Fallot
222	Primary nephrotic syndrome
224	Purpura nephritis
235	Hypoparathyroidism
265	Lipodystrophy
274	Osteogenesis Imperfecta
298	Hereditary pancreatitis
299	Cystic fibrosis

Chloride ion

[1] Chloride

[28] 6, 11, 13, 14, 34, 41, 46, 50, 51, 53, 60, 67, 70, 96, 97, 107, 127, 168, 171, 193, 227, 228, 251, 288, 296, 297, 299, 338 💬

Disease ID	Name
6	Parkinson disease
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
14	Chronic inflammatory demyelinating polyneuropathy
34	Neurofibromatosis
41	Giant cell arteritis
46	Malignant rheumatoid arthritis
50	Dermatomyositis
51	Scleroderma
53	Sjogren syndrome
60	Aplastic anemia
67	Polycystic kidney disease
70	Spinal stenosis
96	Crohn disease
97	Ulcerative colitis
107	Juvenile idiopathic arthritis
127	Frontotemporal lobar degeneration
168	Ehlers-Danlos syndrome
171	Wilson disease
193	Prader-Willi syndrome
227	Osler disease
228	Bronchiolitis obliterans
251	Urea cycle disorder
288	Autoimmune acquired coagulation factor deficiency
296	Biliary atresia
297	Alagille syndrome
299	Cystic fibrosis
338	Progressive familial intrahepatic cholestasis

Cimetidine
(Cimetidine in Sodium Chloride)

[1] Cimetidine

[1] Cimetidine 💬

[1] HRH2 💬

[3] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬

[2] 2, 254 💬

Cobalt chloride

[1] Ceretec

[1] 6 💬

D-glucose
(Dextrose and Sodium Chloride)

[2] D-glucose; Glucose

[1] Glucose 💬

[3] 49, 86, 88 💬

Dexmedetomidine
(Dexmedetomidine Hydrochloride in Sodium Chloride)

[4] Dexdor; DEXMEDETOMIDINA; Dexmedetomidine; DEXMEDETOMIDINE HYDROCHLORIDE

[1] Dexmedetomidine 💬

[3] ADRA2A,
ADRA2B,
ADRA2C 💬

[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬

[14] 2, 4, 6, 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
4	Primary lateral sclerosis
6	Parkinson disease
21	Mitochondrial disease
34	Neurofibromatosis
46	Malignant rheumatoid arthritis
70	Spinal stenosis
107	Juvenile idiopathic arthritis
113	Muscular dystrophy
171	Wilson disease
212	Tricuspid atresia
215	Tetralogy of Fallot
226	Interstitial cystitis with Hunners ulcer
280	Huge arteriovenous malformation with cervicofacial or limb lesion

Dextran
(LMD in Sodium Chloride)

[1] Dextran

[1] Dextran 1 💬

[4] 2, 62, 96, 97 💬

Dextrose, unspecified form
(Potassium Chloride In Dextrose)

[3] Dextrose; Glucose; Smofkabiven

[16] 2, 6, 13, 49, 50, 60, 65, 66, 70, 86, 88, 96, 97, 226, 257, 299 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
6	Parkinson disease
13	Multiple sclerosis/Neuromyelitis optica
49	Systemic lupus erythematosus
50	Dermatomyositis
60	Aplastic anemia
65	Primary immunodeficiency
66	IgA nephropathy
70	Spinal stenosis
86	Pulmonary arterial hypertension
88	Chronic thromboembolic pulmonary hypertension
96	Crohn disease
97	Ulcerative colitis
226	Interstitial cystitis with Hunners ulcer
257	Hepatic glycogenosis
299	Cystic fibrosis

Epinephrine
(Epinephrine Chloride Solution)

[3] Epinephrine; Lidocaine; Xylocaine

[1] Epinephrine 💬

Name	Other Names
Epinephrine	Epinephrine (USP/INN) Adrenaline (JP18) Adrenalin (TN) Auvi-q (TN) Epipen (TN) ADRENALIN(R) CERTA DOSE EPINEPHRINE CONVENIENCE KIT EPINEPHRINE CONVENIENCE KIT EPINEPHRINE PROFESSIONAL EPINEPHRINE PROFESSIONAL EMS EPINEPHRINESNAP-EMS EPINEPHRINESNAP-V SYMJEPI

[9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬

Name	Full Name
ADRA1A	adrenoceptor alpha 1A
ADRA1B	adrenoceptor alpha 1B
ADRA1D	adrenoceptor alpha 1D
ADRA2A	adrenoceptor alpha 2A
ADRA2B	adrenoceptor alpha 2B
ADRA2C	adrenoceptor alpha 2C
ADRB1	adrenoceptor beta 1
ADRB2	adrenoceptor beta 2
ADRB3	adrenoceptor beta 3

[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬

[3] 46, 70, 96 💬

Esmolol
(Esmolol Hydrochloride In Sodium Chloride)

[1] Esmolol

[1] Esmolol 💬

[1] ADRB1 💬

[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬

[1] 58 💬

Fluconazole
(Fluconazole in Sodium Chloride)

[2] Diflucan; FLUCONAZOLE

[1] Fluconazole (FLUCONAZOLE IN SODIUM CHLORIDE) 💬

[2] 96, 225 💬

Gentamicin
(Gentamicin Sulfate in Sodium Chloride)

[2] Gentamicin; Gentamicin Sulfate

[1] Gentamicin 💬

[3] 36, 113, 299 💬

Heparin
(Heparin Sodium In Sodium Chloride)

[2] Heparin; HEPARIN SODIUM

[1] Adomiparin 💬

[1] SERPINC1 💬

[1] Complement and coagulation cascades 💬

[11] 47, 60, 70, 84, 107, 224, 226, 280, 299, 316, 317 💬

Disease ID	Name
47	Buerger disease
60	Aplastic anemia
70	Spinal stenosis
84	Sarcoidosis
107	Juvenile idiopathic arthritis
224	Purpura nephritis
226	Interstitial cystitis with Hunners ulcer
280	Huge arteriovenous malformation with cervicofacial or limb lesion
299	Cystic fibrosis
316	Carnitine cycle disorder
317	Trifunctional protein deficiency

Hydroxyethyl Starch
(Hetastarch in Sodium Chloride)

[1] Hextend

[1] Hetastarch (6% HETASTARCH IN 0.9% SODIUM CHLORIDE) 💬

[2] 96, 97 💬

Lactic acid
(Lactate Chloride Dextrose Inj)

[1] Lactic acid

[1] Lactic acid 💬

[1] 299 💬

Levetiracetam
(Levetiracetam in Sodium Chloride)

[2] KEPPRA; Levetiracetam

[1] Levetiracetam (LEVETIRACETAM IN SODIUM CHLORIDE) 💬

[1] SV2A 💬

[1] ECM-receptor interaction 💬

[5] 2, 4, 6, 13, 307 💬

Lidocaine
(Benzalkonium Chloride and Lidocaine Hydrochloride)

[4] Aloe; Lidocaine; Lignocaine; Xylocaine

[2] Lidocaine ,
Lidocaine hydrochloride monohydrate 💬

Name	Other Names
Lidocaine	Lidocaine (JP18/USP/INN) Dentipatch (TN) Xylocaine (TN) LIDODERM ZTLIDO LIDOCAINE 5% LIDOCAINE PATCH LMR PLUS
Lidocaine hydrochloride monohydrate	Lidocaine hydrochloride monohydrate Lidocaine (TN) Zingo (TN) 1% LIDOCAINE HCI 2% LIDOCAINE HCI LIDENZAL 1% LIDENZAL 2% LIDOCAINE HCI LIDOCAINE HCL LIDOCAINE HYDROCHLORIDE NA PRELIDOPINE PRE-OPERATIVE SYSTEM

[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬

Name	Full Name
SCN1A	sodium voltage-gated channel alpha subunit 1
SCN2A	sodium voltage-gated channel alpha subunit 2
SCN3A	sodium voltage-gated channel alpha subunit 3
SCN5A	sodium voltage-gated channel alpha subunit 5
SCN9A	sodium voltage-gated channel alpha subunit 9

[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬

[13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬

Disease ID	Name
6	Parkinson disease
13	Multiple sclerosis/Neuromyelitis optica
22	Moyamoya disease
34	Neurofibromatosis
46	Malignant rheumatoid arthritis
51	Scleroderma
70	Spinal stenosis
84	Sarcoidosis
86	Pulmonary arterial hypertension
107	Juvenile idiopathic arthritis
168	Ehlers-Danlos syndrome
226	Interstitial cystitis with Hunners ulcer
256	Muscle glycogenosis

Lysine
(Effervescent Potassium Chloride)

[1] Lysine

[1] Lysine 💬

[5] 13, 19, 97, 228, 299 💬

Meropenem
(Meropenem and Sodium Chloride)

[1] MEROPENEM

[2] Meropenem (MEROPENEM AND SODIUM CHLORIDE),
Meropenem 💬

[2] 60, 299 💬

Methylene blue
(Methylthioninium Chloride Cosmo)

[2] METHYLENE BLUE; Methylthioninium chloride

[2] Methylene blue (Methylthioninium chloride),
Methylthioninium chloride hydrate 💬

Name	Other Names
Methylene blue	Methylene blue (USP) Methylthioninium chloride Methylthioninium chloride proveblue (TN) PROVAYBLUE
Methylthioninium chloride hydrate	Methylthioninium chloride hydrate (JAN) Methylene blue (TN)

[2] 97, 127 💬

N-acetylsulfanilyl chloride

[0]

[4] 36, 51, 96, 97 💬

Oxybutynin
(Penta-oxybutynin Chloride Tablets)

[1] Oxybutynin

[1] Oxybutynin 💬

[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬

Name	Full Name
CHRM1	cholinergic receptor muscarinic 1
CHRM2	cholinergic receptor muscarinic 2
CHRM3	cholinergic receptor muscarinic 3
CHRM4	cholinergic receptor muscarinic 4
CHRM5	cholinergic receptor muscarinic 5

[3] 6, 13, 53 💬

Sodium bicarbonate
(Sodium Bicarbonate-chloride Dry Concentrate R04955)

[1] Sodium Bicarbonate

[1] Sodium bicarbonate 💬

[1] 299 💬

Sodium chloride

[6] Lactated Ringers; Natriumchlorid; REBIF; SALINE; Sodium chloride; SPORANOX

[1] Sodium chloride 💬

Name	Other Names
Sodium chloride	Sodium chloride (JP18/USP) Adsorbanac (TN) 0.9% SODIUM CHLORIDE BACTERIOSTATIC SODIUM CHLORIDE NACELLATE SOLUTION 0.9% - 1000ML NACELLATE SOLUTION 0.9% - 100ML NACELLATE SOLUTION 0.9% - 250ML NACELLATE SOLUTION 0.9% - 500ML SODIUM CHLORIDE FOR IRRIGATION 3% SODIUM CHLORIDE AMPHENOL-40 CORVATROL 0.9% HAEMONETICS 0.9 % SODIUM CHLORIDE

[20] 6, 11, 13, 14, 34, 41, 46, 50, 51, 53, 60, 67, 70, 96, 168, 193, 227, 228, 288, 299 💬

Disease ID	Name
6	Parkinson disease
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
14	Chronic inflammatory demyelinating polyneuropathy
34	Neurofibromatosis
41	Giant cell arteritis
46	Malignant rheumatoid arthritis
50	Dermatomyositis
51	Scleroderma
53	Sjogren syndrome
60	Aplastic anemia
67	Polycystic kidney disease
70	Spinal stenosis
96	Crohn disease
168	Ehlers-Danlos syndrome
193	Prader-Willi syndrome
227	Osler disease
228	Bronchiolitis obliterans
288	Autoimmune acquired coagulation factor deficiency
299	Cystic fibrosis

Tobramycin
(Tobramycin in Sodium Chloride)

[9] Bethkis; TOBI; TOBI PODHALER; TOBRAMICINA; TOBRAMYCIN; Tobramycin inhalation solution; TOBRAMYCIN SULFATE; Tobramycine; Tobramycinum

[1] Tobramycin 💬

[1] 299 💬

Tranexamic acid
(Tranexamic Acid In Sodium Chloride)

[1] Tranexamic acid

[1] Tranexamic acid (TRANEXAMIC ACID IN SODIUM CHLORIDE) 💬

[1] PLG 💬

[4] Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection 💬

[7] 46, 70, 215, 227, 274, 288, 299 💬

Yellow fever vaccine

[1] Yellow fever vaccine

[1] Yellow fever vaccine (SODIUM CHLORIDE) 💬

[8] 40, 44, 46, 50, 51, 52, 53, 107 💬

Disease ID	Name
40	Takayasu arteritis
44	Wegener granulomatosis
46	Malignant rheumatoid arthritis
50	Dermatomyositis
51	Scleroderma
52	Mixed connective tissue disease
53	Sjogren syndrome
107	Juvenile idiopathic arthritis