Drug Description in Trials / DrugBank / KEGG DRUG

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No.

DrugBank

Drug (Description in trials)

KEGG DRUG

KEGG GENES

KEGG PATHWAY

Disease ID

1

Acetaminophen
(Acetaminophen Gelatin Caplets)

[4] Acetaminophen; PARACETAMOL; Tylenol; Ultracet

[1] Acetaminophen 💬

[2] PTGS1,
PTGS2 💬

[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬

[15] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬

Disease ID	Name
3	Spinal muscular atrophy
6	Parkinson disease
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
34	Neurofibromatosis
35	Pemphigus
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
51	Scleroderma
70	Spinal stenosis
86	Pulmonary arterial hypertension
222	Primary nephrotic syndrome
256	Muscle glycogenosis
271	Ankylosing spondylitis
337	Homocystinuria

2

Cyclosporine
(Sandimmune Soft Gelatin Cap 100mg)

[10] Ciclosporin; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; Neoral; Restasis

[1] Cyclosporine 💬

[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬

Name	Full Name
PPP3CA	protein phosphatase 3 catalytic subunit alpha
PPP3CB	protein phosphatase 3 catalytic subunit beta
PPP3CC	protein phosphatase 3 catalytic subunit gamma
PPP3R1	protein phosphatase 3 regulatory subunit B, alpha
PPP3R2	protein phosphatase 3 regulatory subunit B, beta

[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬

[44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬

Disease ID	Name
11	Myasthenia gravis
19	Lysosomal storage disease
20	Adrenoleukodystrophy
26	HTLV-1-associated myelopathy
28	Systemic amyloidosis
36	Epidermolysis bullosa
38	Stevens-Johnson syndrome
39	Toxic epidermal necrolysis
40	Takayasu arteritis
41	Giant cell arteritis
42	Polyarteritis nodosa
45	Eosinophilic granulomatosis with Polyangiitis
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
50	Dermatomyositis
53	Sjogren syndrome
55	Relapsing polychondritis
56	Behcet disease
58	Hypertrophic cardiomyopathy
60	Aplastic anemia
61	Autoimmune hemolytic anemia
62	Paroxysmal nocturnal hemoglobinuria
63	Idiopathic thrombocytopenic purpura
64	Thrombotic thrombocytopenic purpura
65	Primary immunodeficiency
90	Retinitis pigmentosa
93	Primary biliary cholangitis
95	Autoimmune hepatitis
97	Ulcerative colitis
107	Juvenile idiopathic arthritis
113	Muscular dystrophy
162	Pemphigoid
164	Oculocutaneous albinism
222	Primary nephrotic syndrome
226	Interstitial cystitis with Hunners ulcer
228	Bronchiolitis obliterans
234	Peroxisomal disease (except Adrenoleukodystrophy)
269	Pyogenic arthritis
274	Osteogenesis Imperfecta
283	Acquired pure red cell aplasia
284	Diamond-Blackfan anemia
285	Fanconi anemia
302	Leber hereditary optic neuropathy
326	Osteopetrosis

3

[3] Gelatin; Gelatine; Sulfur Colloid

[2] Gelatin ,
Donkey glue (Gelatin (TN)) 💬

-

-

[7] 19, 28, 62, 78, 97, 269, 299 💬

4

Loperamide
(Lil Drug Store Anti-Diarrheal Soft Gelatin)

[2] LOPERAMIDE; Loperamide hydrochloride

[1] Loperamide 💬

[3] OPRD1,
OPRK1,
OPRM1 💬

[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬

[2] 13, 97 💬

5

Loratadine
(Loratadine Soft Gelatin Capsules)

[2] Loratadina; Loratadine

[1] Loratadine 💬

[1] HRH1 💬

[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬

[4] 13, 46, 89, 98 💬

6

Spheramine
(Allogeneic human retinal pigment epithelial cells on gelatin microcarriers)

-

-

-

[1] 6 💬