DDrare
Disease
Drug
Target Gene/Pathway
Contact
JA
Drug
Description in Trials
/
DrugBank
/
KEGG DRUG
Search
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
Other
Search results
10
50
100
ALL
drugs per page:
Showing 1 to 1 of 1 drugs
Filter by
Reset
|
No.
DrugBank
Drug (Description in trials)
KEGG DRUG
KEGG GENES
KEGG PATHWAY
Disease ID
1
Sirolimus
[3]
Rapamune
Rapamune
;
Rapamycin
;
Sirolimus
[1]
Sirolimus
Sirolimus
💬
1.
Sirolimus
×
Name
Other Names
Sirolimus
Sirolimus (JAN/USAN/INN)
Rapamune (TN)
Rapamycin (TN)
FYARRO
HYFTOR
[1]
MTOR
MTOR
💬
1.
Sirolimus
×
Name
Full Name
MTOR
mechanistic target of rapamycin kinase
[51]
AMPK signaling pathway
AMPK signaling pathway
,
Acute myeloid leukemia
,
Adipocytokine signaling pathway
,
Alzheimer disease
,
Amyotrophic lateral sclerosis
,
Apelin signaling pathway
,
Autophagy - animal
,
Autophagy - other
,
Breast cancer
,
Cellular senescence
,
Central carbon metabolism in cancer
,
Chemical carcinogenesis - receptor activation
,
Choline metabolism in cancer
,
Colorectal cancer
,
Diabetic cardiomyopathy
,
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
ErbB signaling pathway
,
Gastric cancer
,
Glioma
,
Growth hormone synthesis, secretion and action
,
HIF-1 signaling pathway
,
Hepatocellular carcinoma
,
Herpes simplex virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Human papillomavirus infection
,
Huntington disease
,
Insulin resistance
,
Insulin signaling pathway
,
JAK-STAT signaling pathway
,
Kaposi sarcoma-associated herpesvirus infection
,
Longevity regulating pathway
,
Longevity regulating pathway - multiple species
,
MicroRNAs in cancer
,
Neutrophil extracellular trap formation
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
PI3K-Akt signaling pathway
,
Pancreatic cancer
,
Pathways in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Phospholipase D signaling pathway
,
Prostate cancer
,
Proteoglycans in cancer
,
Shigellosis
,
Spinocerebellar ataxia
,
Th17 cell differentiation
,
Thermogenesis
,
Thyroid hormone signaling pathway
,
Type II diabetes mellitus
,
mTOR signaling pathway
💬
[51]
AMPK signaling pathway
,
Acute myeloid leukemia
,
Adipocytokine signaling pathway
,
Alzheimer dise
...
[40]
2
2
,
13
,
15
,
17
,
19
,
34
,
35
,
36
,
46
,
49
,
51
,
53
,
60
,
61
,
62
,
63
,
65
,
66
,
67
,
84
,
85
,
86
,
89
,
96
,
98
,
137
,
157
,
158
,
192
,
193
,
222
,
256
,
277
,
278
,
279
,
280
,
281
,
283
,
300
,
331
💬
[40]
2
,
13
,
15
,
17
,
19
,
34
,
35
,
36
,
46
,
49
,
51
,
53
,
60
,
61
,
62
,
63
,
65
,
66
,
67
,
84
,
85
,
86
,
89
,
96
, ...
1.
Sirolimus
×
Disease ID
Name
2
Amyotrophic lateral sclerosis
13
Multiple sclerosis/Neuromyelitis optica
15
Inclusion body myositis
17
Multiple system atrophy
19
Lysosomal storage disease
34
Neurofibromatosis
35
Pemphigus
36
Epidermolysis bullosa
46
Malignant rheumatoid arthritis
49
Systemic lupus erythematosus
51
Scleroderma
53
Sjogren syndrome
60
Aplastic anemia
61
Autoimmune hemolytic anemia
62
Paroxysmal nocturnal hemoglobinuria
63
Idiopathic thrombocytopenic purpura
65
Primary immunodeficiency
66
IgA nephropathy
67
Polycystic kidney disease
84
Sarcoidosis
85
Idiopathic interstitial pneumonia
86
Pulmonary arterial hypertension
89
Lymphangioleiomyomatosis
96
Crohn disease
98
Eosinophilic gastrointestinal disease
137
Focal cortical dysplasia
157
Sturge-Weber syndrome
158
Tuberous sclerosis
192
Cockayne syndrome
193
Prader-Willi syndrome
222
Primary nephrotic syndrome
256
Muscle glycogenosis
277
Lymphangiomatosis
278
Huge lymphatic malformation with cervicofacial lesion
279
Huge venous malformation with cervical, oral and pharyngeal diffuse lesion
280
Huge arteriovenous malformation with cervicofacial or limb lesion
281
Klippel-Trenaunay-Weber syndrome
283
Acquired pure red cell aplasia
300
IgG4-related disease
331
Idiopathic multicentric castleman disease