Drug Description in Trials / DrugBank / KEGG DRUG

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No.

DrugBank

Drug (Description in trials)

KEGG DRUG

KEGG GENES

KEGG PATHWAY

Disease ID

1

Brimonidine
(BRIMONIDINE TARTRATE and TIMOLOL MALEATE)

[2] Brimonidine; Brimonidine tartrate

[1] Brimonidine 💬

[3] ADRA2A,
ADRA2B,
ADRA2C 💬

[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬

[2] 13, 90 💬

2

Dorzolamide
(Dorzolamide Hydrochloride and Timolol Maleate Ophthalmic Solution)

[1] Dorzolamide

[1] Dorzolamide 💬

[13] CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬

Name	Full Name
CA1	carbonic anhydrase 1
CA12	carbonic anhydrase 12
CA13	carbonic anhydrase 13
CA14	carbonic anhydrase 14
CA2	carbonic anhydrase 2
CA3	carbonic anhydrase 3
CA4	carbonic anhydrase 4
CA5A	carbonic anhydrase 5A
CA5B	carbonic anhydrase 5B
CA6	carbonic anhydrase 6
CA7	carbonic anhydrase 7
CA8	carbonic anhydrase 8
CA9	carbonic anhydrase 9

[7] Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬

[1] 90 💬

3

Timolol
(Dorzolamide Hydrochloride-Timolol Maleate)

[2] Timolol; TIMOLOL MALEATE

[2] Timolol ,
Timolol 💬

[2] ADRB1,
ADRB2 💬

[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬

[2] 157, 227 💬