Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
2 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
BRAF [4] BRAF, FLT3, KIT, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
3 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
CSF1R [3] CSF1R, FLT3, KIT 💬
|
Pexidartinib Pexidartinib 💬
| Pexidartinib | 034 [1] 34 💬
|
4 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
CSF1R [3] CSF1R, FLT3, KIT 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
5 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
KIT [1] KIT 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
6 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
KIT [1] KIT 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
7 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
8 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
9 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
10 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
11 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
12 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
13 | Adherens junction 💬 9 genes, 19 drugs (DrugBank) and 23 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
14 | Adherens junction 💬 9 genes, 19 drugs (DrugBank) and 23 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
15 | Adherens junction 💬 9 genes, 19 drugs (DrugBank) and 23 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
16 | Adherens junction 💬 9 genes, 19 drugs (DrugBank) and 23 diseases |
MET [1] MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
17 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
18 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
19 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
20 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
21 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
SCN5A [1] SCN5A 💬
|
Lamotrigine Lamotrigine 💬
| Lamotrigine | 013 [5] 13, 34, 38, 114, 144 💬
|
22 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
SCN5A [1] SCN5A 💬
|
Lidocaine Lidocaine 💬
| Lidocaine | 006 [13] 6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
|
23 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
SCN5A [1] SCN5A 💬
|
Lidocaine hydrochloride monohydrate Lidocaine hydrochloride monohydrate 💬
| Lidocaine | 006 [13] 6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
|
24 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
IL10 [4] IL10, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
25 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
26 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
CCL2 [5] CCL2, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
27 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
CDK4 [1] CDK4 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 [1] 34 💬
|
28 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
29 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
30 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
VEGFA [1] VEGFA 💬
|
Ranibizumab Ranibizumab 💬
| Ranibizumab | 034 [4] 34, 166, 227, 301 💬
|
31 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
IL1B [3] IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
32 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
33 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
34 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
BRAF [2] BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
35 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
MAP2K1 [1] MAP2K1 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
36 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
MAP2K1 [1] MAP2K1 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
37 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
MAP2K1 [1] MAP2K1 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
38 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
39 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
SLC6A3 [1] SLC6A3 💬
|
Methylphenidate Methylphenidate 💬
| Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬
|
40 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
IL10 [2] IL10, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
41 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
42 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
43 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
BRAF [2] BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
44 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
IL1A [4] IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
45 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
46 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
47 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
48 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
49 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
50 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
51 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
PTGS2 [1] PTGS2 💬
|
Acetaminophen Acetaminophen 💬
| Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
|
52 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
53 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
PTGS2 [1] PTGS2 💬
|
Diclofenac Diclofenac 💬
| Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬
|
54 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
55 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Vinblastine Vinblastine 💬
| Vinblastine | 034 [2] 34, 65 💬
|
56 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Vincristine Vincristine 💬
| Vincristine | 026 [4] 26, 34, 65, 331 💬
|
57 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
IL10 [4] IL10, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
58 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
59 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
SLC6A3 [1] SLC6A3 💬
|
Methylphenidate Methylphenidate 💬
| Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬
|
60 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
HMGCR [1] HMGCR 💬
|
Lovastatin Lovastatin 💬
| Lovastatin | 006 [11] 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
|
61 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
HMGCR [1] HMGCR 💬
|
Simvastatin Simvastatin 💬
| Simvastatin | 006 [21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
|
62 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
63 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
64 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
ERBB4 [1] ERBB4 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
65 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
66 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
67 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
68 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
69 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Vinblastine Vinblastine 💬
| Vinblastine | 034 [2] 34, 65 💬
|
70 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Vincristine Vincristine 💬
| Vincristine | 026 [4] 26, 34, 65, 331 💬
|
71 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
DHFR [2] DHFR, DHFR2 💬
|
Methotrexate Methotrexate 💬
| Methotrexate | 011 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
|
72 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
IL1B [3] IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
73 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
74 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
75 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
76 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
77 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
78 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
79 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
80 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
81 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
82 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
83 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
84 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
85 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
86 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
87 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
88 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
89 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
90 | Arachidonic acid metabolism 💬 4 genes, 26 drugs (DrugBank) and 43 diseases |
PTGS1 [2] PTGS1, PTGS2 💬
|
Acetaminophen Acetaminophen 💬
| Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
|
91 | Arachidonic acid metabolism 💬 4 genes, 26 drugs (DrugBank) and 43 diseases |
PTGS1 [2] PTGS1, PTGS2 💬
|
Diclofenac Diclofenac 💬
| Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬
|
92 | Arachidonic acid metabolism 💬 4 genes, 26 drugs (DrugBank) and 43 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
93 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
IL10 [2] IL10, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
94 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
95 | Autoimmune thyroid disease 💬 22 genes, 15 drugs (DrugBank) and 35 diseases |
IL10 [1] IL10 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
96 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
97 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
98 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
99 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
100 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
101 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
102 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
103 | Autophagy - other 💬 1 gene, 3 drugs (DrugBank) and 41 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
104 | Autophagy - other 💬 1 gene, 3 drugs (DrugBank) and 41 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
105 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
ABL1 [1] ABL1 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
106 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
ABL1 [1] ABL1 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
107 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
MET [1] MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
108 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
109 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
110 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
111 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
112 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
113 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
114 | Bacterial invasion of epithelial cells 💬 5 genes, 7 drugs (DrugBank) and 13 diseases |
MET [1] MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
115 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 60 diseases |
HMGCR [1] HMGCR 💬
|
Lovastatin Lovastatin 💬
| Lovastatin | 006 [11] 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
|
116 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 60 diseases |
HMGCR [1] HMGCR 💬
|
Simvastatin Simvastatin 💬
| Simvastatin | 006 [21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
|
117 | Biosynthesis of cofactors 💬 10 genes, 10 drugs (DrugBank) and 51 diseases |
DHFR [2] DHFR, DHFR2 💬
|
Methotrexate Methotrexate 💬
| Methotrexate | 011 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
|
118 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
119 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
BRAF [2] BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
120 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
CDK4 [1] CDK4 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 [1] 34 💬
|
121 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
122 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
123 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
124 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
125 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
126 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
127 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
128 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
129 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
VEGFA [1] VEGFA 💬
|
Ranibizumab Ranibizumab 💬
| Ranibizumab | 034 [4] 34, 166, 227, 301 💬
|
130 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
131 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
BRAF [4] BRAF, FLT4, KIT, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
132 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
CDK4 [2] CDK4, CDK6 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 [1] 34 💬
|
133 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
134 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
135 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
136 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
FLT4 [1] FLT4 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 [1] 34 💬
|
137 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
FLT4 [1] FLT4 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 [1] 34 💬
|
138 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
FLT4 [2] FLT4, KIT 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
139 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
KIT [1] KIT 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
140 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
KIT [1] KIT 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
141 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
KIT [1] KIT 💬
|
Pexidartinib Pexidartinib 💬
| Pexidartinib | 034 [1] 34 💬
|
142 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
143 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
144 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
145 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
146 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
147 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
148 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL10 [4] IL10, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
149 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬
|
Acetaminophen Acetaminophen 💬
| Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
|
150 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
151 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬
|
Diclofenac Diclofenac 💬
| Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬
|
152 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
153 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
154 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
155 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
156 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EGFR [3] EGFR, ERBB2, ERBB4 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
157 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
FLT1 [3] FLT1, FLT4, KDR 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 [1] 34 💬
|
158 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
FLT1 [3] FLT1, FLT4, KDR 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 [1] 34 💬
|
159 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
FLT1 [6] FLT1, FLT4, KDR, PDGFRA, PDGFRB, RET 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
160 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
FLT4 [4] FLT4, KDR, PDGFRB, RET 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
161 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
KDR [2] KDR, MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
162 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
163 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
164 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
165 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
VEGFA [1] VEGFA 💬
|
Ranibizumab Ranibizumab 💬
| Ranibizumab | 034 [4] 34, 166, 227, 301 💬
|
166 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
167 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
BRAF [2] BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
168 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
169 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
170 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
171 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
172 | Cell cycle 💬 10 genes, 9 drugs (DrugBank) and 21 diseases |
ABL1 [1] ABL1 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
173 | Cell cycle 💬 10 genes, 9 drugs (DrugBank) and 21 diseases |
ABL1 [1] ABL1 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
174 | Cell cycle 💬 10 genes, 9 drugs (DrugBank) and 21 diseases |
CDK4 [2] CDK4, CDK6 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 [1] 34 💬
|
175 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
CDK4 [2] CDK4, CDK6 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 [1] 34 💬
|
176 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
IL1A [2] IL1A, IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
177 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
178 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
179 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
180 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
181 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
182 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
183 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
184 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
185 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
186 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
187 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
FLT3 [2] FLT3, KIT 💬
|
Pexidartinib Pexidartinib 💬
| Pexidartinib | 034 [1] 34 💬
|
188 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
FLT3 [5] FLT3, KIT, PDGFRA, PDGFRB, RET 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
189 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
FLT3 [5] FLT3, KIT, PDGFRB, RAF1, RET 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
190 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
KIT [2] KIT, PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
191 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
KIT [3] KIT, PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
192 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
193 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
194 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
195 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
196 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MET [1] MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
197 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
198 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
199 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬
|
Dexmedetomidine Dexmedetomidine 💬
| Dexmedetomidine | 002 [14] 2 , 4 , 6 , 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
|
200 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
201 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
202 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
203 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
204 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
205 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
CCL2 [5] CCL2, IL10, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
206 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
207 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases |
PTGS2 [1] PTGS2 💬
|
Acetaminophen Acetaminophen 💬
| Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
|
208 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
209 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases |
PTGS2 [1] PTGS2 💬
|
Diclofenac Diclofenac 💬
| Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬
|
210 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
ABL1 [1] ABL1 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
211 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
ABL1 [1] ABL1 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
212 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
213 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
BRAF [2] BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
214 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
215 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
EGFR [1] EGFR 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
216 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
EGFR [1] EGFR 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
217 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
218 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
219 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
220 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
221 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
MET [1] MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
222 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
223 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
VEGFA [1] VEGFA 💬
|
Ranibizumab Ranibizumab 💬
| Ranibizumab | 034 [4] 34, 166, 227, 301 💬
|
224 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
225 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
EGFR [1] EGFR 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
226 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
EGFR [1] EGFR 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
227 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
228 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
229 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
230 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
231 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
232 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
233 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
234 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
VDR [1] VDR 💬
|
Cholecalciferol Cholecalciferol 💬
| Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
|
235 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
236 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
VEGFA [1] VEGFA 💬
|
Ranibizumab Ranibizumab 💬
| Ranibizumab | 034 [4] 34, 166, 227, 301 💬
|
237 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
238 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
BRAF [2] BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
239 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
CCL2 [1] CCL2 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
240 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
MAP2K1 [1] MAP2K1 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
241 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
MAP2K1 [1] MAP2K1 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
242 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
MAP2K1 [1] MAP2K1 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
243 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
244 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
245 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
EGFR [1] EGFR 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
246 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
EGFR [1] EGFR 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
247 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
248 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
249 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
250 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
251 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
252 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
253 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
254 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
255 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
256 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
PDGFRB [2] PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
257 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
MAP2K1 [1] MAP2K1 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
258 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
MAP2K1 [1] MAP2K1 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
259 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
MAP2K1 [1] MAP2K1 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
260 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
261 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
ABL1 [1] ABL1 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
262 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
ABL1 [1] ABL1 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
263 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
264 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
BRAF [2] BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
265 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
CDK4 [2] CDK4, CDK6 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 [1] 34 💬
|
266 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
267 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
268 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
269 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
270 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
SLC6A3 [1] SLC6A3 💬
|
Methylphenidate Methylphenidate 💬
| Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬
|
271 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
272 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
BRAF [2] BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
273 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
274 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
EGFR [1] EGFR 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
275 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
EGFR [1] EGFR 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
276 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
277 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
278 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
279 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
280 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
281 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
282 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
283 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
284 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
EGFR [1] EGFR 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
285 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
EGFR [1] EGFR 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
286 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2b Interferon alfa-2b 💬
| Interferon alfa-2b | 025 [2] 25, 34 💬
|
287 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TLR7 [1] TLR7 💬
|
Imiquimod Imiquimod 💬
| Imiquimod | 034 [2] 34, 51 💬
|
288 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
289 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
290 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
BRAF [1] BRAF 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
291 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
CDK4 [2] CDK4, CDK6 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 [1] 34 💬
|
292 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
293 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
EGFR [1] EGFR 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
294 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
EGFR [1] EGFR 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
295 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
296 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
297 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
298 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
299 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CCL2 [6] CCL2, IL10, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
300 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CSF1R [1] CSF1R 💬
|
Pexidartinib Pexidartinib 💬
| Pexidartinib | 034 [1] 34 💬
|
301 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CSF1R [1] CSF1R 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
302 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CSF3R [1] CSF3R 💬
|
Filgrastim Filgrastim 💬
| Filgrastim | 002 [35] 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
|
303 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2b Interferon alfa-2b 💬
| Interferon alfa-2b | 025 [2] 25, 34 💬
|
304 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
305 | Cytosolic DNA-sensing pathway 💬 17 genes, 12 drugs (DrugBank) and 28 diseases |
IL1B [2] IL1B, IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
306 | Diabetic cardiomyopathy 💬 26 genes, 42 drugs (DrugBank) and 73 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
307 | Diabetic cardiomyopathy 💬 26 genes, 42 drugs (DrugBank) and 73 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
308 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
309 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
310 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
SCN1A [1] SCN1A 💬
|
Lamotrigine Lamotrigine 💬
| Lamotrigine | 013 [5] 13, 34, 38, 114, 144 💬
|
311 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
SCN1A [1] SCN1A 💬
|
Lidocaine Lidocaine 💬
| Lidocaine | 006 [13] 6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
|
312 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
SCN1A [1] SCN1A 💬
|
Lidocaine hydrochloride monohydrate Lidocaine hydrochloride monohydrate 💬
| Lidocaine | 006 [13] 6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
|
313 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
SLC6A3 [1] SLC6A3 💬
|
Methylphenidate Methylphenidate 💬
| Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬
|
314 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
AXL [3] AXL, KDR, MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
315 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
316 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
BRAF [4] BRAF, KDR, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
317 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
318 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
319 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
320 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
IL6 [1] IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
321 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
KDR [1] KDR 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 [1] 34 💬
|
322 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
KDR [1] KDR 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 [1] 34 💬
|
323 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
KDR [3] KDR, PDGFRA, PDGFRB 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
324 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
325 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
326 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
327 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
328 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
329 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
330 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
331 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
332 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
333 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
VEGFA [1] VEGFA 💬
|
Ranibizumab Ranibizumab 💬
| Ranibizumab | 034 [4] 34, 166, 227, 301 💬
|
334 | Endocrine and other factor-regulated calcium reabsorption 💬 8 genes, 27 drugs (DrugBank) and 55 diseases |
VDR [1] VDR 💬
|
Cholecalciferol Cholecalciferol 💬
| Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
|
335 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
336 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
BRAF [2] BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
337 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
CDK4 [1] CDK4 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 [1] 34 💬
|
338 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
339 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
340 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
341 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
342 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
343 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
344 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
345 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
346 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
347 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
348 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
EGFR [1] EGFR 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
349 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
EGFR [1] EGFR 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
350 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
351 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
PDGFRA [1] PDGFRA 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
352 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
PDGFRA [1] PDGFRA 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
353 | Endometrial cancer 💬 10 genes, 18 drugs (DrugBank) and 20 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
354 | Endometrial cancer 💬 10 genes, 18 drugs (DrugBank) and 20 diseases |
BRAF [2] BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
355 | Endometrial cancer 💬 10 genes, 18 drugs (DrugBank) and 20 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
356 | Endometrial cancer 💬 10 genes, 18 drugs (DrugBank) and 20 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
357 | Endometrial cancer 💬 10 genes, 18 drugs (DrugBank) and 20 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
358 | Endometrial cancer 💬 10 genes, 18 drugs (DrugBank) and 20 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
359 | Endometrial cancer 💬 10 genes, 18 drugs (DrugBank) and 20 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
360 | Endometrial cancer 💬 10 genes, 18 drugs (DrugBank) and 20 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
361 | Endometrial cancer 💬 10 genes, 18 drugs (DrugBank) and 20 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
362 | Epithelial cell signaling in Helicobacter pylori infection 💬 12 genes, 17 drugs (DrugBank) and 21 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
363 | Epithelial cell signaling in Helicobacter pylori infection 💬 12 genes, 17 drugs (DrugBank) and 21 diseases |
EGFR [1] EGFR 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
364 | Epithelial cell signaling in Helicobacter pylori infection 💬 12 genes, 17 drugs (DrugBank) and 21 diseases |
EGFR [1] EGFR 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
365 | Epithelial cell signaling in Helicobacter pylori infection 💬 12 genes, 17 drugs (DrugBank) and 21 diseases |
MET [1] MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
366 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
CDK4 [2] CDK4, CDK6 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 [1] 34 💬
|
367 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2b Interferon alfa-2b 💬
| Interferon alfa-2b | 025 [2] 25, 34 💬
|
368 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
IL6 [2] IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
369 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
370 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
ABL1 [1] ABL1 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
371 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
ABL1 [1] ABL1 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
372 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
373 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
BRAF [2] BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
374 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
375 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
376 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
EGFR [3] EGFR, ERBB2, ERBB4 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
377 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
378 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
379 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
380 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
381 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
382 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
383 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
384 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
EGFR [1] EGFR 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
385 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
EGFR [1] EGFR 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
386 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
387 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
388 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
389 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
390 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
391 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
392 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
393 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
394 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
395 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
396 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
397 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
398 | Fc gamma R-mediated phagocytosis 💬 9 genes, 12 drugs (DrugBank) and 15 diseases |
MAP2K1 [1] MAP2K1 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
399 | Fc gamma R-mediated phagocytosis 💬 9 genes, 12 drugs (DrugBank) and 15 diseases |
MAP2K1 [1] MAP2K1 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
400 | Fc gamma R-mediated phagocytosis 💬 9 genes, 12 drugs (DrugBank) and 15 diseases |
MAP2K1 [1] MAP2K1 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
401 | Fc gamma R-mediated phagocytosis 💬 9 genes, 12 drugs (DrugBank) and 15 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
402 | Fc gamma R-mediated phagocytosis 💬 9 genes, 12 drugs (DrugBank) and 15 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
403 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
CCL2 [4] CCL2, IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
404 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
KDR [1] KDR 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 [1] 34 💬
|
405 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
KDR [1] KDR 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
406 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
KDR [1] KDR 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 [1] 34 💬
|
407 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
KDR [1] KDR 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
408 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
KDR [1] KDR 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
409 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
410 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
411 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
VEGFA [1] VEGFA 💬
|
Ranibizumab Ranibizumab 💬
| Ranibizumab | 034 [4] 34, 166, 227, 301 💬
|
412 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
413 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
BRAF [5] BRAF, FLT4, KDR, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
414 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
415 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
416 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
417 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
FLT1 [3] FLT1, FLT4, KDR 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 [1] 34 💬
|
418 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
FLT1 [3] FLT1, FLT4, KDR 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 [1] 34 💬
|
419 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
FLT1 [5] FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
420 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
KDR [2] KDR, MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
421 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
MAP2K1 [1] MAP2K1 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
422 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
MAP2K1 [1] MAP2K1 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
423 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
MAP2K1 [1] MAP2K1 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
424 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
425 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
426 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
427 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
428 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
VEGFA [1] VEGFA 💬
|
Ranibizumab Ranibizumab 💬
| Ranibizumab | 034 [4] 34, 166, 227, 301 💬
|
429 | Folate biosynthesis 💬 6 genes, 4 drugs (DrugBank) and 39 diseases |
DHFR [2] DHFR, DHFR2 💬
|
Methotrexate Methotrexate 💬
| Methotrexate | 011 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
|
430 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
431 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
BRAF [2] BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
432 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
433 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
EGFR [1] EGFR 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
434 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
EGFR [1] EGFR 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
435 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
IL10 [2] IL10, IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
436 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
437 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
438 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
439 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
440 | GABAergic synapse 💬 29 genes, 38 drugs (DrugBank) and 55 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Propofol Propofol 💬
| Propofol | 006 [9] 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬
|
441 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
442 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
EGFR [1] EGFR 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
443 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
EGFR [1] EGFR 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
444 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
445 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
446 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
447 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
448 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
449 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
450 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
451 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
PDGFRB [2] PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
452 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Vinblastine Vinblastine 💬
| Vinblastine | 034 [2] 34, 65 💬
|
453 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Vincristine Vincristine 💬
| Vincristine | 026 [4] 26, 34, 65, 331 💬
|
454 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
455 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
BRAF [2] BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
456 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
457 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
458 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
459 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
460 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
461 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
462 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
463 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
MET [1] MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
464 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
465 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
466 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
467 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
BRAF [3] BRAF, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
468 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
CDK4 [2] CDK4, CDK6 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 [1] 34 💬
|
469 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
470 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
EGFR [1] EGFR 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
471 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
EGFR [1] EGFR 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
472 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
473 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
474 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
475 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
476 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
477 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
478 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
479 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
480 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
481 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
482 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
483 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
484 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
485 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
486 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
487 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases |
EGFR [1] EGFR 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
488 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases |
EGFR [1] EGFR 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
489 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
490 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
491 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
492 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
493 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
494 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
IL1A [4] IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
495 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
496 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
497 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
498 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
499 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
500 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
501 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
502 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
503 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
CSF1R [3] CSF1R, FLT3, KIT 💬
|
Pexidartinib Pexidartinib 💬
| Pexidartinib | 034 [1] 34 💬
|
504 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
CSF1R [3] CSF1R, FLT3, KIT 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
505 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
CSF3R [1] CSF3R 💬
|
Filgrastim Filgrastim 💬
| Filgrastim | 002 [35] 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
|
506 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
FLT3 [2] FLT3, KIT 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
507 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL1A [4] IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
508 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
KIT [1] KIT 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
509 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
KIT [1] KIT 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
510 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
511 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
512 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
BRAF [2] BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
513 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
IFNAR1 [1] IFNAR1 💬
|
Interferon alfa-2b Interferon alfa-2b 💬
| Interferon alfa-2b | 025 [2] 25, 34 💬
|
514 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
IL6 [2] IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
515 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
516 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
517 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
518 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
519 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
520 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
521 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
BRAF [2] BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
522 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
CDK4 [2] CDK4, CDK6 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 [1] 34 💬
|
523 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
524 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
EGFR [1] EGFR 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
525 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
EGFR [1] EGFR 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
526 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2b Interferon alfa-2b 💬
| Interferon alfa-2b | 025 [2] 25, 34 💬
|
527 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
528 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
529 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
530 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
531 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
532 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
533 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
534 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
BRAF [2] BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
535 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
CDK4 [2] CDK4, CDK6 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 [1] 34 💬
|
536 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
537 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
EGFR [1] EGFR 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
538 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
EGFR [1] EGFR 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
539 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
540 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
541 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
542 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
543 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MET [1] MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
544 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
545 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
546 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
547 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2b Interferon alfa-2b 💬
| Interferon alfa-2b | 025 [2] 25, 34 💬
|
548 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
549 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
550 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
551 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
552 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
553 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
554 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
FLT1 [1] FLT1 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 [1] 34 💬
|
555 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
FLT1 [1] FLT1 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 [1] 34 💬
|
556 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
FLT1 [1] FLT1 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
557 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
IL6 [1] IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
558 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
559 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
560 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
561 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
562 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
563 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
564 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
565 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
VEGFA [1] VEGFA 💬
|
Ranibizumab Ranibizumab 💬
| Ranibizumab | 034 [4] 34, 166, 227, 301 💬
|
566 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
567 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
CDK4 [2] CDK4, CDK6 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 [1] 34 💬
|
568 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
569 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
EGFR [1] EGFR 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
570 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
EGFR [1] EGFR 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
571 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
572 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
573 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
574 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
575 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
576 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
577 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
578 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PDGFRA [1] PDGFRA 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
579 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PDGFRA [1] PDGFRA 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
580 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PTGS2 [1] PTGS2 💬
|
Acetaminophen Acetaminophen 💬
| Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
|
581 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
582 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PTGS2 [1] PTGS2 💬
|
Diclofenac Diclofenac 💬
| Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬
|
583 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
584 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
585 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
586 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
VEGFA [1] VEGFA 💬
|
Ranibizumab Ranibizumab 💬
| Ranibizumab | 034 [4] 34, 166, 227, 301 💬
|
587 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
588 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
589 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
590 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
591 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
592 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
593 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
594 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
595 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
596 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
CDK4 [2] CDK4, CDK6 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 [1] 34 💬
|
597 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
598 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
EGFR [1] EGFR 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
599 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
EGFR [1] EGFR 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
600 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2b Interferon alfa-2b 💬
| Interferon alfa-2b | 025 [2] 25, 34 💬
|
601 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
602 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
603 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
604 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
605 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
606 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
607 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
PDGFRB [1] PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
608 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
PDGFRB [1] PDGFRB 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
609 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
PDGFRB [2] PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
610 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
PTGS2 [1] PTGS2 💬
|
Acetaminophen Acetaminophen 💬
| Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
|
611 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
612 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
PTGS2 [1] PTGS2 💬
|
Diclofenac Diclofenac 💬
| Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬
|
613 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
614 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
615 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
616 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
VEGFA [1] VEGFA 💬
|
Ranibizumab Ranibizumab 💬
| Ranibizumab | 034 [4] 34, 166, 227, 301 💬
|
617 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
CDK4 [1] CDK4 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 [1] 34 💬
|
618 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
IL6 [2] IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
619 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
620 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
621 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
622 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
623 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
624 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
625 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
626 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Vinblastine Vinblastine 💬
| Vinblastine | 034 [2] 34, 65 💬
|
627 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Vincristine Vincristine 💬
| Vincristine | 026 [4] 26, 34, 65, 331 💬
|
628 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
IL6 [2] IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
629 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
630 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
631 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
PTGS2 [1] PTGS2 💬
|
Acetaminophen Acetaminophen 💬
| Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
|
632 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
633 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
PTGS2 [1] PTGS2 💬
|
Diclofenac Diclofenac 💬
| Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬
|
634 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
635 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL10 [5] IL10, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
636 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
637 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
IL1B [1] IL1B 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
638 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
CCL2 [5] CCL2, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
639 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
CDK4 [2] CDK4, CDK6 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 [1] 34 💬
|
640 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2b Interferon alfa-2b 💬
| Interferon alfa-2b | 025 [2] 25, 34 💬
|
641 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
642 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
643 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
644 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
645 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
646 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
TLR7 [1] TLR7 💬
|
Imiquimod Imiquimod 💬
| Imiquimod | 034 [2] 34, 51 💬
|
647 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
648 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
IL6 [2] IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
649 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
650 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
651 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
652 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
653 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
BRAF [2] BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
654 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
655 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
656 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
657 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
658 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
659 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
660 | Intestinal immune network for IgA production 💬 16 genes, 27 drugs (DrugBank) and 47 diseases |
IL10 [2] IL10, IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
661 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
CSF3R [1] CSF3R 💬
|
Filgrastim Filgrastim 💬
| Filgrastim | 002 [35] 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
|
662 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
663 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
EGFR [1] EGFR 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
664 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
EGFR [1] EGFR 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
665 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2b Interferon alfa-2b 💬
| Interferon alfa-2b | 025 [2] 25, 34 💬
|
666 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL10 [2] IL10, IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
667 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
668 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
669 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
670 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
671 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
672 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
PDGFRB [2] PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
673 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
CDK4 [2] CDK4, CDK6 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 [1] 34 💬
|
674 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2b Interferon alfa-2b 💬
| Interferon alfa-2b | 025 [2] 25, 34 💬
|
675 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
IL6 [1] IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
676 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
677 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
678 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
679 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
680 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
681 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
682 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
PTGS2 [1] PTGS2 💬
|
Acetaminophen Acetaminophen 💬
| Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
|
683 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
684 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
PTGS2 [1] PTGS2 💬
|
Diclofenac Diclofenac 💬
| Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬
|
685 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
686 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
687 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
VEGFA [1] VEGFA 💬
|
Ranibizumab Ranibizumab 💬
| Ranibizumab | 034 [4] 34, 166, 227, 301 💬
|
688 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
IL1B [3] IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
689 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
690 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
IL10 [4] IL10, IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
691 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
PTGS2 [1] PTGS2 💬
|
Acetaminophen Acetaminophen 💬
| Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
|
692 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
693 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
PTGS2 [1] PTGS2 💬
|
Diclofenac Diclofenac 💬
| Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬
|
694 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
695 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
696 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
697 | Long-term depression 💬 13 genes, 19 drugs (DrugBank) and 32 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
698 | Long-term depression 💬 13 genes, 19 drugs (DrugBank) and 32 diseases |
BRAF [2] BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
699 | Long-term depression 💬 13 genes, 19 drugs (DrugBank) and 32 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
700 | Long-term depression 💬 13 genes, 19 drugs (DrugBank) and 32 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
701 | Long-term depression 💬 13 genes, 19 drugs (DrugBank) and 32 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
702 | Long-term depression 💬 13 genes, 19 drugs (DrugBank) and 32 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
703 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
704 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
BRAF [2] BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
705 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
706 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
707 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
708 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
709 | Longevity regulating pathway 💬 11 genes, 20 drugs (DrugBank) and 68 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
710 | Longevity regulating pathway 💬 11 genes, 20 drugs (DrugBank) and 68 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
711 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
712 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
713 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
CCL2 [5] CCL2, IL10, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
714 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
MET [1] MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
715 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
716 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
717 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
BRAF [7] BRAF, FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
718 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
CSF1R [8] CSF1R, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
719 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
CSF1R [3] CSF1R, FLT3, KIT 💬
|
Pexidartinib Pexidartinib 💬
| Pexidartinib | 034 [1] 34 💬
|
720 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
721 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
722 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
EGFR [3] EGFR, ERBB2, ERBB4 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
723 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
FLT1 [3] FLT1, FLT4, KDR 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 [1] 34 💬
|
724 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
FLT1 [3] FLT1, FLT4, KDR 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 [1] 34 💬
|
725 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IL1A [3] IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
726 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
KDR [2] KDR, MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
727 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
KIT [2] KIT, PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
728 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
KIT [3] KIT, PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
729 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
730 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
731 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
732 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
733 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
734 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
735 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
VEGFA [1] VEGFA 💬
|
Ranibizumab Ranibizumab 💬
| Ranibizumab | 034 [4] 34, 166, 227, 301 💬
|
736 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
CDK4 [2] CDK4, CDK6 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 [1] 34 💬
|
737 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2b Interferon alfa-2b 💬
| Interferon alfa-2b | 025 [2] 25, 34 💬
|
738 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL1A [3] IL1A, IL1B, IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
739 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
TLR7 [1] TLR7 💬
|
Imiquimod Imiquimod 💬
| Imiquimod | 034 [2] 34, 51 💬
|
740 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
KIT [1] KIT 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
741 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
KIT [1] KIT 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
742 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
KIT [1] KIT 💬
|
Pexidartinib Pexidartinib 💬
| Pexidartinib | 034 [1] 34 💬
|
743 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
KIT [1] KIT 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
744 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
KIT [2] KIT, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
745 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
746 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
747 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
748 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
749 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
750 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
BRAF [3] BRAF, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
751 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
CDK4 [2] CDK4, CDK6 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 [1] 34 💬
|
752 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
753 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
EGFR [1] EGFR 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
754 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
EGFR [1] EGFR 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
755 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
756 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
757 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
758 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
759 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
MET [1] MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
760 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
761 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
762 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
763 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
DHFR [2] DHFR, DHFR2 💬
|
Methotrexate Methotrexate 💬
| Methotrexate | 011 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
|
764 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HMGCR [1] HMGCR 💬
|
Lovastatin Lovastatin 💬
| Lovastatin | 006 [11] 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
|
765 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HMGCR [1] HMGCR 💬
|
Simvastatin Simvastatin 💬
| Simvastatin | 006 [21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
|
766 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS1 [2] PTGS1, PTGS2 💬
|
Acetaminophen Acetaminophen 💬
| Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
|
767 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS1 [2] PTGS1, PTGS2 💬
|
Diclofenac Diclofenac 💬
| Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬
|
768 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
769 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
ABL1 [2] ABL1, PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
770 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
ABL1 [3] ABL1, PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
771 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
CDK6 [1] CDK6 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 [1] 34 💬
|
772 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
773 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
774 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
775 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
776 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
777 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
778 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
779 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MET [1] MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
780 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
781 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
782 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
783 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PDGFRB [2] PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
784 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PTGS2 [1] PTGS2 💬
|
Acetaminophen Acetaminophen 💬
| Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
|
785 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
786 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PTGS2 [1] PTGS2 💬
|
Diclofenac Diclofenac 💬
| Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬
|
787 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
788 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
VEGFA [1] VEGFA 💬
|
Ranibizumab Ranibizumab 💬
| Ranibizumab | 034 [4] 34, 166, 227, 301 💬
|
789 | Mineral absorption 💬 8 genes, 13 drugs (DrugBank) and 41 diseases |
VDR [1] VDR 💬
|
Cholecalciferol Cholecalciferol 💬
| Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
|
790 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Propofol Propofol 💬
| Propofol | 006 [9] 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬
|
791 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
792 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
BRAF [2] BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
793 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
794 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
795 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
796 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
797 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
798 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
799 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
800 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
801 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
802 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
BRAF [2] BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
803 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2b Interferon alfa-2b 💬
| Interferon alfa-2b | 025 [2] 25, 34 💬
|
804 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
805 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
806 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
807 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
808 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
809 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
810 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2b Interferon alfa-2b 💬
| Interferon alfa-2b | 025 [2] 25, 34 💬
|
811 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IL1A [3] IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
812 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
813 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬
|
Dexmedetomidine Dexmedetomidine 💬
| Dexmedetomidine | 002 [14] 2 , 4 , 6 , 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
|
814 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Propofol Propofol 💬
| Propofol | 006 [9] 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬
|
815 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
ABL1 [1] ABL1 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
816 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
ABL1 [1] ABL1 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
817 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
818 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
BRAF [2] BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
819 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
820 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
821 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
822 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
823 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
824 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
825 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
826 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
827 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
828 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
829 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
830 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
TLR7 [1] TLR7 💬
|
Imiquimod Imiquimod 💬
| Imiquimod | 034 [2] 34, 51 💬
|
831 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
IL1B [2] IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
832 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 [1] PTGS2 💬
|
Acetaminophen Acetaminophen 💬
| Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
|
833 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
834 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 [1] PTGS2 💬
|
Diclofenac Diclofenac 💬
| Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬
|
835 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
836 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Propofol Propofol 💬
| Propofol | 006 [9] 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬
|
837 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
838 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2b Interferon alfa-2b 💬
| Interferon alfa-2b | 025 [2] 25, 34 💬
|
839 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
840 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL1A [4] IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
841 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
842 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
ALK [1] ALK 💬
|
Brigatinib Brigatinib 💬
| Brigatinib | 034 [1] 34 💬
|
843 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
ALK [1] ALK 💬
|
Crizotinib Crizotinib 💬
| Crizotinib | 034 [1] 34 💬
|
844 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
845 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
BRAF [3] BRAF, RAF1, RET 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
846 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
CDK4 [2] CDK4, CDK6 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 [1] 34 💬
|
847 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
848 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
849 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
850 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
851 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
852 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
853 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
854 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
MET [1] MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
855 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
RET [1] RET 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
856 | One carbon pool by folate 💬 3 genes, 2 drugs (DrugBank) and 38 diseases |
DHFR [2] DHFR, DHFR2 💬
|
Methotrexate Methotrexate 💬
| Methotrexate | 011 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
|
857 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
MAP2K1 [1] MAP2K1 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
858 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
MAP2K1 [1] MAP2K1 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
859 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
MAP2K1 [1] MAP2K1 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
860 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
861 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
CSF1R [1] CSF1R 💬
|
Pexidartinib Pexidartinib 💬
| Pexidartinib | 034 [1] 34 💬
|
862 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
CSF1R [1] CSF1R 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
863 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2b Interferon alfa-2b 💬
| Interferon alfa-2b | 025 [2] 25, 34 💬
|
864 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IL1A [3] IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
865 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
MAP2K1 [1] MAP2K1 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
866 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
MAP2K1 [1] MAP2K1 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
867 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
MAP2K1 [1] MAP2K1 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
868 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
869 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
870 | Ovarian steroidogenesis 💬 7 genes, 36 drugs (DrugBank) and 52 diseases |
PTGS2 [1] PTGS2 💬
|
Acetaminophen Acetaminophen 💬
| Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
|
871 | Ovarian steroidogenesis 💬 7 genes, 36 drugs (DrugBank) and 52 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
872 | Ovarian steroidogenesis 💬 7 genes, 36 drugs (DrugBank) and 52 diseases |
PTGS2 [1] PTGS2 💬
|
Diclofenac Diclofenac 💬
| Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬
|
873 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
874 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
EGFR [1] EGFR 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
875 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
EGFR [1] EGFR 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
876 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
877 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
878 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
879 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
880 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
PTGS2 [1] PTGS2 💬
|
Acetaminophen Acetaminophen 💬
| Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
|
881 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
882 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
PTGS2 [1] PTGS2 💬
|
Diclofenac Diclofenac 💬
| Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬
|
883 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
884 | p53 signaling pathway 💬 5 genes, 4 drugs (DrugBank) and 13 diseases |
CDK4 [2] CDK4, CDK6 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 [1] 34 💬
|
885 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
886 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
BRAF [2] BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
887 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
CDK4 [2] CDK4, CDK6 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 [1] 34 💬
|
888 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
889 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
890 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
891 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
MAP2K1 [1] MAP2K1 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
892 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
MAP2K1 [1] MAP2K1 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
893 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
MAP2K1 [1] MAP2K1 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
894 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
895 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
896 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
897 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
898 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
VEGFA [1] VEGFA 💬
|
Ranibizumab Ranibizumab 💬
| Ranibizumab | 034 [4] 34, 166, 227, 301 💬
|
899 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
900 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
BRAF [2] BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
901 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
902 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
EGFR [1] EGFR 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
903 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
EGFR [1] EGFR 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
904 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
MAP2K1 [1] MAP2K1 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
905 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
MAP2K1 [1] MAP2K1 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
906 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
MAP2K1 [1] MAP2K1 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
907 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
908 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
VDR [1] VDR 💬
|
Cholecalciferol Cholecalciferol 💬
| Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
|
909 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
SLC6A3 [1] SLC6A3 💬
|
Methylphenidate Methylphenidate 💬
| Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬
|
910 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Vinblastine Vinblastine 💬
| Vinblastine | 034 [2] 34, 65 💬
|
911 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Vincristine Vincristine 💬
| Vincristine | 026 [4] 26, 34, 65, 331 💬
|
912 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
ABL1 [1] ABL1 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
913 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
ABL1 [1] ABL1 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
914 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
IL1B [3] IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
915 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
916 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Vinblastine Vinblastine 💬
| Vinblastine | 034 [2] 34, 65 💬
|
917 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Vincristine Vincristine 💬
| Vincristine | 026 [4] 26, 34, 65, 331 💬
|
918 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ABL1 [3] ABL1, KIT, PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
919 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ABL1 [4] ABL1, KIT, PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
920 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ALK [1] ALK 💬
|
Brigatinib Brigatinib 💬
| Brigatinib | 034 [1] 34 💬
|
921 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ALK [1] ALK 💬
|
Crizotinib Crizotinib 💬
| Crizotinib | 034 [1] 34 💬
|
922 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
923 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
BRAF [7] BRAF, FLT3, FLT4, KIT, PDGFRB, RAF1, RET 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
924 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
CDK4 [2] CDK4, CDK6 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 [1] 34 💬
|
925 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
CSF1R [7] CSF1R, FLT3, FLT4, KIT, PDGFRA, PDGFRB, RET 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
926 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
CSF1R [3] CSF1R, FLT3, KIT 💬
|
Pexidartinib Pexidartinib 💬
| Pexidartinib | 034 [1] 34 💬
|
927 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
CSF3R [1] CSF3R 💬
|
Filgrastim Filgrastim 💬
| Filgrastim | 002 [35] 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
|
928 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
929 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
930 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
931 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
FLT4 [1] FLT4 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 [1] 34 💬
|
932 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
FLT4 [1] FLT4 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 [1] 34 💬
|
933 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2b Interferon alfa-2b 💬
| Interferon alfa-2b | 025 [2] 25, 34 💬
|
934 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL6 [1] IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
935 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
936 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
937 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
938 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
939 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MET [1] MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
940 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
941 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
942 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGS2 [1] PTGS2 💬
|
Acetaminophen Acetaminophen 💬
| Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
|
943 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
944 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGS2 [1] PTGS2 💬
|
Diclofenac Diclofenac 💬
| Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬
|
945 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
946 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
VEGFA [1] VEGFA 💬
|
Ranibizumab Ranibizumab 💬
| Ranibizumab | 034 [4] 34, 166, 227, 301 💬
|
947 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
948 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
BRAF [2] BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
949 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
IL1A [4] IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
950 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
951 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
952 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
953 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
954 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
955 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
956 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PTGS2 [1] PTGS2 💬
|
Acetaminophen Acetaminophen 💬
| Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
|
957 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
958 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PTGS2 [1] PTGS2 💬
|
Diclofenac Diclofenac 💬
| Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬
|
959 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
SLC6A3 [1] SLC6A3 💬
|
Methylphenidate Methylphenidate 💬
| Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬
|
960 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
961 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Vinblastine Vinblastine 💬
| Vinblastine | 034 [2] 34, 65 💬
|
962 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Vincristine Vincristine 💬
| Vincristine | 026 [4] 26, 34, 65, 331 💬
|
963 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
ALK [1] ALK 💬
|
Brigatinib Brigatinib 💬
| Brigatinib | 034 [1] 34 💬
|
964 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
ALK [1] ALK 💬
|
Crizotinib Crizotinib 💬
| Crizotinib | 034 [1] 34 💬
|
965 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
966 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
EGFR [1] EGFR 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
967 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
EGFR [1] EGFR 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
968 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
969 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
970 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
971 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
972 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
973 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
974 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
975 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL10 [5] IL10, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
976 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
977 | Phagosome 💬 13 genes, 10 drugs (DrugBank) and 21 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Vinblastine Vinblastine 💬
| Vinblastine | 034 [2] 34, 65 💬
|
978 | Phagosome 💬 13 genes, 10 drugs (DrugBank) and 21 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Vincristine Vincristine 💬
| Vincristine | 026 [4] 26, 34, 65, 331 💬
|
979 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
980 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
EGFR [1] EGFR 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
981 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
EGFR [1] EGFR 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
982 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
KIT [1] KIT 💬
|
Pexidartinib Pexidartinib 💬
| Pexidartinib | 034 [1] 34 💬
|
983 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
KIT [2] KIT, PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
984 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
KIT [3] KIT, PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
985 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
KIT [3] KIT, PDGFRA, PDGFRB 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
986 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
KIT [3] KIT, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
987 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
988 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
989 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
990 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
991 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
992 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
993 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CDK4 [2] CDK4, CDK6 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 [1] 34 💬
|
994 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CSF1R [8] CSF1R, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
995 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CSF1R [3] CSF1R, FLT3, KIT 💬
|
Pexidartinib Pexidartinib 💬
| Pexidartinib | 034 [1] 34 💬
|
996 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CSF3R [1] CSF3R 💬
|
Filgrastim Filgrastim 💬
| Filgrastim | 002 [35] 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
|
997 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
998 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
999 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
EGFR [3] EGFR, ERBB2, ERBB4 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
1000 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
FLT1 [3] FLT1, FLT4, KDR 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 [1] 34 💬
|
1001 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
FLT1 [3] FLT1, FLT4, KDR 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 [1] 34 💬
|
1002 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
FLT3 [6] FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
1003 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2b Interferon alfa-2b 💬
| Interferon alfa-2b | 025 [2] 25, 34 💬
|
1004 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL6 [1] IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
1005 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
KDR [2] KDR, MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
1006 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
KIT [2] KIT, PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
1007 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
KIT [3] KIT, PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
1008 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
1009 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
1010 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
1011 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
1012 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
1013 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
1014 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
1015 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
VEGFA [1] VEGFA 💬
|
Ranibizumab Ranibizumab 💬
| Ranibizumab | 034 [4] 34, 166, 227, 301 💬
|
1016 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PTGS1 [1] PTGS1 💬
|
Acetaminophen Acetaminophen 💬
| Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
|
1017 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PTGS1 [1] PTGS1 💬
|
Diclofenac Diclofenac 💬
| Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬
|
1018 | Platinum drug resistance 💬 9 genes, 15 drugs (DrugBank) and 23 diseases |
ERBB2 [1] ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
1019 | Platinum drug resistance 💬 9 genes, 15 drugs (DrugBank) and 23 diseases |
ERBB2 [1] ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
1020 | Platinum drug resistance 💬 9 genes, 15 drugs (DrugBank) and 23 diseases |
TOP2A [2] TOP2A, TOP2B 💬
|
Doxorubicin Doxorubicin 💬
| Doxorubicin | 026 [5] 26, 28, 34, 65, 331 💬
|
1021 | Platinum drug resistance 💬 9 genes, 15 drugs (DrugBank) and 23 diseases |
TOP2A [2] TOP2A, TOP2B 💬
|
Etoposide Etoposide 💬
| Etoposide | 011 [11] 11, 13, 14, 26, 28, 34, 60, 65, 85, 164, 331 💬
|
1022 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
IL1A [4] IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
1023 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
1024 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Vinblastine Vinblastine 💬
| Vinblastine | 034 [2] 34, 65 💬
|
1025 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Vincristine Vincristine 💬
| Vincristine | 026 [4] 26, 34, 65, 331 💬
|
1026 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
1027 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
BRAF [2] BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
1028 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
MAP2K1 [1] MAP2K1 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
1029 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
MAP2K1 [1] MAP2K1 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
1030 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
MAP2K1 [1] MAP2K1 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
1031 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
1032 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
1033 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
1034 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
1035 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
1036 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
1037 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
1038 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
BRAF [3] BRAF, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
1039 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
1040 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
1041 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
1042 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
1043 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
1044 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
1045 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
1046 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
1047 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
1048 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
1049 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
1050 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
1051 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
1052 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
BRAF [3] BRAF, KDR, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
1053 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
1054 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
1055 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
EGFR [3] EGFR, ERBB2, ERBB4 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
1056 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
KDR [1] KDR 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 [1] 34 💬
|
1057 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
KDR [1] KDR 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 [1] 34 💬
|
1058 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
KDR [1] KDR 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
1059 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
KDR [2] KDR, MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
1060 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
1061 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
1062 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
1063 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
1064 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
1065 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
1066 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
1067 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
1068 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
1069 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
VEGFA [1] VEGFA 💬
|
Ranibizumab Ranibizumab 💬
| Ranibizumab | 034 [4] 34, 166, 227, 301 💬
|
1070 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
1071 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
BRAF [6] BRAF, FLT4, KDR, KIT, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
1072 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
CSF1R [7] CSF1R, FLT1, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
1073 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
CSF1R [2] CSF1R, KIT 💬
|
Pexidartinib Pexidartinib 💬
| Pexidartinib | 034 [1] 34 💬
|
1074 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
1075 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
EGFR [1] EGFR 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
1076 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
EGFR [1] EGFR 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
1077 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
FLT1 [3] FLT1, FLT4, KDR 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 [1] 34 💬
|
1078 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
FLT1 [3] FLT1, FLT4, KDR 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 [1] 34 💬
|
1079 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
KDR [2] KDR, MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
1080 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
KIT [2] KIT, PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
1081 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
KIT [3] KIT, PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
1082 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
1083 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
1084 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
1085 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
1086 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
1087 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
VEGFA [1] VEGFA 💬
|
Ranibizumab Ranibizumab 💬
| Ranibizumab | 034 [4] 34, 166, 227, 301 💬
|
1088 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
ABL1 [3] ABL1, KIT, PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
1089 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
ABL1 [4] ABL1, KIT, PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
1090 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
CSF1R [8] CSF1R, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
1091 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
CSF1R [3] CSF1R, FLT3, KIT 💬
|
Pexidartinib Pexidartinib 💬
| Pexidartinib | 034 [1] 34 💬
|
1092 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
1093 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
EGFR [1] EGFR 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
1094 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
EGFR [1] EGFR 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
1095 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
FLT1 [3] FLT1, FLT4, KDR 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 [1] 34 💬
|
1096 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
FLT1 [3] FLT1, FLT4, KDR 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 [1] 34 💬
|
1097 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
FLT3 [6] FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
1098 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
KDR [2] KDR, MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
1099 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
1100 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
1101 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
1102 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
1103 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
1104 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
VEGFA [1] VEGFA 💬
|
Ranibizumab Ranibizumab 💬
| Ranibizumab | 034 [4] 34, 166, 227, 301 💬
|
1105 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
1106 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
BRAF [3] BRAF, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
1107 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
1108 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
EGFR [1] EGFR 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
1109 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
EGFR [1] EGFR 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
1110 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
1111 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
1112 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
1113 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
1114 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
1115 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
1116 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
1117 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases |
PTGS1 [2] PTGS1, PTGS2 💬
|
Acetaminophen Acetaminophen 💬
| Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
|
1118 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases |
PTGS1 [2] PTGS1, PTGS2 💬
|
Diclofenac Diclofenac 💬
| Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬
|
1119 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
1120 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
1121 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
EGFR [1] EGFR 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
1122 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
EGFR [1] EGFR 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
1123 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
1124 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
1125 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
1126 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
1127 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
1128 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
1129 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
VEGFA [1] VEGFA 💬
|
Ranibizumab Ranibizumab 💬
| Ranibizumab | 034 [4] 34, 166, 227, 301 💬
|
1130 | Renal cell carcinoma 💬 12 genes, 15 drugs (DrugBank) and 19 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
1131 | Renal cell carcinoma 💬 12 genes, 15 drugs (DrugBank) and 19 diseases |
BRAF [2] BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
1132 | Renal cell carcinoma 💬 12 genes, 15 drugs (DrugBank) and 19 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
1133 | Renal cell carcinoma 💬 12 genes, 15 drugs (DrugBank) and 19 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
1134 | Renal cell carcinoma 💬 12 genes, 15 drugs (DrugBank) and 19 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
1135 | Renal cell carcinoma 💬 12 genes, 15 drugs (DrugBank) and 19 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
1136 | Renal cell carcinoma 💬 12 genes, 15 drugs (DrugBank) and 19 diseases |
MET [1] MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
1137 | Renal cell carcinoma 💬 12 genes, 15 drugs (DrugBank) and 19 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
1138 | Renal cell carcinoma 💬 12 genes, 15 drugs (DrugBank) and 19 diseases |
VEGFA [1] VEGFA 💬
|
Ranibizumab Ranibizumab 💬
| Ranibizumab | 034 [4] 34, 166, 227, 301 💬
|
1139 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Propofol Propofol 💬
| Propofol | 006 [9] 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬
|
1140 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases |
PTGS2 [1] PTGS2 💬
|
Acetaminophen Acetaminophen 💬
| Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
|
1141 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
1142 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases |
PTGS2 [1] PTGS2 💬
|
Diclofenac Diclofenac 💬
| Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬
|
1143 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
CCL2 [5] CCL2, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
1144 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
FLT1 [1] FLT1 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 [1] 34 💬
|
1145 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
FLT1 [1] FLT1 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 [1] 34 💬
|
1146 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
FLT1 [1] FLT1 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
1147 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
1148 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
1149 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
VEGFA [1] VEGFA 💬
|
Ranibizumab Ranibizumab 💬
| Ranibizumab | 034 [4] 34, 166, 227, 301 💬
|
1150 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
1151 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
1152 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
IL1B [3] IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
1153 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
1154 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
1155 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
1156 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
1157 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
1158 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
1159 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Vinblastine Vinblastine 💬
| Vinblastine | 034 [2] 34, 65 💬
|
1160 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Vincristine Vincristine 💬
| Vincristine | 026 [4] 26, 34, 65, 331 💬
|
1161 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
1162 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
BRAF [2] BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
1163 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
GABRB1 [3] GABRB1, GABRB2, GABRB3 💬
|
Propofol Propofol 💬
| Propofol | 006 [9] 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬
|
1164 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
MAP2K1 [1] MAP2K1 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
1165 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
MAP2K1 [1] MAP2K1 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
1166 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
MAP2K1 [1] MAP2K1 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
1167 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
1168 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
PTGS1 [2] PTGS1, PTGS2 💬
|
Acetaminophen Acetaminophen 💬
| Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
|
1169 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
PTGS1 [2] PTGS1, PTGS2 💬
|
Diclofenac Diclofenac 💬
| Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬
|
1170 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
1171 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
1172 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
EGFR [1] EGFR 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
1173 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
EGFR [1] EGFR 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
1174 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
IL1B [2] IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
1175 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
1176 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
1177 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
1178 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
1179 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
1180 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
1181 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
1182 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
1183 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
CDK4 [2] CDK4, CDK6 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 [1] 34 💬
|
1184 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PTGS2 [1] PTGS2 💬
|
Acetaminophen Acetaminophen 💬
| Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
|
1185 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
1186 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PTGS2 [1] PTGS2 💬
|
Diclofenac Diclofenac 💬
| Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬
|
1187 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
1188 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
1189 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
1190 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
1191 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
1192 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
1193 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
1194 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
1195 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
1196 | Staphylococcus aureus infection 💬 12 genes, 19 drugs (DrugBank) and 34 diseases |
IL10 [1] IL10 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
1197 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A2 [2] SLC6A2, SLC6A3 💬
|
Methylphenidate Methylphenidate 💬
| Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬
|
1198 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
IL10 [2] IL10, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
1199 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
1200 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
CDK4 [1] CDK4 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 [1] 34 💬
|
1201 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
IL10 [2] IL10, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
1202 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
1203 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
1204 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
1205 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
1206 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
1207 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
1208 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬
|
Propofol Propofol 💬
| Propofol | 006 [9] 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬
|
1209 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬
|
Lamotrigine Lamotrigine 💬
| Lamotrigine | 013 [5] 13, 34, 38, 114, 144 💬
|
1210 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬
|
Lidocaine Lidocaine 💬
| Lidocaine | 006 [13] 6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
|
1211 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬
|
Lidocaine hydrochloride monohydrate Lidocaine hydrochloride monohydrate 💬
| Lidocaine | 006 [13] 6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
|
1212 | Terpenoid backbone biosynthesis 💬 4 genes, 12 drugs (DrugBank) and 53 diseases |
FNTA [2] FNTA, FNTB 💬
|
Tipifarnib Tipifarnib 💬
| Tipifarnib | 034 [1] 34 💬
|
1213 | Terpenoid backbone biosynthesis 💬 4 genes, 12 drugs (DrugBank) and 53 diseases |
HMGCR [1] HMGCR 💬
|
Lovastatin Lovastatin 💬
| Lovastatin | 006 [11] 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
|
1214 | Terpenoid backbone biosynthesis 💬 4 genes, 12 drugs (DrugBank) and 53 diseases |
HMGCR [1] HMGCR 💬
|
Simvastatin Simvastatin 💬
| Simvastatin | 006 [21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
|
1215 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
1216 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
1217 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL1B [2] IL1B, IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
1218 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
1219 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
1220 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
1221 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
1222 | Thyroid cancer 💬 8 genes, 16 drugs (DrugBank) and 28 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
1223 | Thyroid cancer 💬 8 genes, 16 drugs (DrugBank) and 28 diseases |
BRAF [2] BRAF, RET 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
1224 | Thyroid cancer 💬 8 genes, 16 drugs (DrugBank) and 28 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
1225 | Thyroid cancer 💬 8 genes, 16 drugs (DrugBank) and 28 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
1226 | Thyroid cancer 💬 8 genes, 16 drugs (DrugBank) and 28 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
1227 | Thyroid cancer 💬 8 genes, 16 drugs (DrugBank) and 28 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
1228 | Thyroid cancer 💬 8 genes, 16 drugs (DrugBank) and 28 diseases |
RET [1] RET 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
1229 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
1230 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
1231 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
1232 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
1233 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
1234 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
1235 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
1236 | Tight junction 💬 11 genes, 29 drugs (DrugBank) and 45 diseases |
CDK4 [1] CDK4 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 [1] 34 💬
|
1237 | Tight junction 💬 11 genes, 29 drugs (DrugBank) and 45 diseases |
ERBB2 [1] ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
1238 | Tight junction 💬 11 genes, 29 drugs (DrugBank) and 45 diseases |
ERBB2 [1] ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
1239 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
1240 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
MAP2K1 [1] MAP2K1 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
1241 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
MAP2K1 [1] MAP2K1 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
1242 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
MAP2K1 [1] MAP2K1 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
1243 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
1244 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PTGS2 [1] PTGS2 💬
|
Acetaminophen Acetaminophen 💬
| Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
|
1245 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
1246 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PTGS2 [1] PTGS2 💬
|
Diclofenac Diclofenac 💬
| Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬
|
1247 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
1248 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2b Interferon alfa-2b 💬
| Interferon alfa-2b | 025 [2] 25, 34 💬
|
1249 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
IL1B [3] IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
1250 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
1251 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
1252 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
1253 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
1254 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
TLR7 [1] TLR7 💬
|
Imiquimod Imiquimod 💬
| Imiquimod | 034 [2] 34, 51 💬
|
1255 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
1256 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
IL10 [2] IL10, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
1257 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
1258 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
CSF1R [3] CSF1R, FLT1, FLT3 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
1259 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
CSF1R [2] CSF1R, FLT3 💬
|
Pexidartinib Pexidartinib 💬
| Pexidartinib | 034 [1] 34 💬
|
1260 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
FLT1 [1] FLT1 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 [1] 34 💬
|
1261 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
FLT1 [1] FLT1 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 [1] 34 💬
|
1262 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
FLT3 [1] FLT3 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
1263 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
IL6 [1] IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
1264 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
MET [1] MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
1265 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
IL10 [5] IL10, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
1266 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
1267 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
1268 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
VDR [1] VDR 💬
|
Cholecalciferol Cholecalciferol 💬
| Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
|
1269 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
IL1A [3] IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
1270 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
1271 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
1272 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
1273 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
1274 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
1275 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
1276 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
BRAF [2] BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
1277 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
1278 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
1279 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
1280 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
1281 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
KDR [1] KDR 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 [1] 34 💬
|
1282 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
KDR [1] KDR 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
1283 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
KDR [1] KDR 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 [1] 34 💬
|
1284 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
KDR [1] KDR 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
1285 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
KDR [2] KDR, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
1286 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
1287 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
1288 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
1289 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
1290 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
PTGS2 [1] PTGS2 💬
|
Acetaminophen Acetaminophen 💬
| Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
|
1291 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
1292 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
PTGS2 [1] PTGS2 💬
|
Diclofenac Diclofenac 💬
| Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬
|
1293 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
1294 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
VEGFA [1] VEGFA 💬
|
Ranibizumab Ranibizumab 💬
| Ranibizumab | 034 [4] 34, 166, 227, 301 💬
|
1295 | Viral carcinogenesis 💬 25 genes, 23 drugs (DrugBank) and 40 diseases |
CDK4 [2] CDK4, CDK6 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 [1] 34 💬
|
1296 | Viral myocarditis 💬 10 genes, 19 drugs (DrugBank) and 46 diseases |
ABL1 [1] ABL1 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
1297 | Viral myocarditis 💬 10 genes, 19 drugs (DrugBank) and 46 diseases |
ABL1 [1] ABL1 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
1298 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
CCL2 [4] CCL2, IL10, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
1299 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
CSF1R [1] CSF1R 💬
|
Pexidartinib Pexidartinib 💬
| Pexidartinib | 034 [1] 34 💬
|
1300 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
CSF1R [1] CSF1R 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
1301 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
1302 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
CCL2 [5] CCL2, IL10, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
1303 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
1304 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
1305 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
1306 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
1307 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|