Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
KIT [1] KIT 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
2 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
KIT [1] KIT 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
3 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
KIT [1] KIT 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
4 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
5 | Adherens junction 💬 9 genes, 19 drugs (DrugBank) and 23 diseases |
FGFR1 [1] FGFR1 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
6 | Adherens junction 💬 9 genes, 19 drugs (DrugBank) and 23 diseases |
FYN [3] FYN, SRC, YES1 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
7 | Adherens junction 💬 9 genes, 19 drugs (DrugBank) and 23 diseases |
FYN [3] FYN, SRC, YES1 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
8 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
9 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
10 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
11 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
12 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
13 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
14 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
ADRB1 [1] ADRB1 💬
|
Nebivolol Nebivolol 💬
| Nebivolol | 017 [4] 17, 85, 113, 167 💬
|
15 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
ADRB2 [1] ADRB2 💬
|
Formoterol Formoterol 💬
| Formoterol | 085 [3] 85, 228, 299 💬
|
16 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
ADRB2 [1] ADRB2 💬
|
Albuterol Albuterol 💬
| Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
|
17 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
18 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
IL10 [4] IL10, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
19 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
20 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
21 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
22 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
23 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
24 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
CCL2 [5] CCL2, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
25 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
26 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
27 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
28 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
29 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
30 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
31 | Alanine, aspartate and glutamate metabolism 💬 5 genes, 3 drugs (DrugBank) and 19 diseases |
ABAT [4] ABAT, ALDH5A1, GAD1, GAD2 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
32 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
IL1B [3] IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
33 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
34 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
35 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
36 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
37 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
38 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
39 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
40 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
IL10 [2] IL10, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
41 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
42 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
43 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
44 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
45 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
46 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
IL1A [4] IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
47 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
48 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
49 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
50 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
51 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
52 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
53 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
54 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Paclitaxel Paclitaxel 💬
| Paclitaxel | 046 [2] 46, 85 💬
|
55 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
IL10 [4] IL10, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
56 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
57 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
58 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
59 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
60 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
61 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
62 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
63 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
64 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
65 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
GRIN1 [6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
66 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
67 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
68 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
69 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
70 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
71 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
72 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
73 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
74 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Paclitaxel Paclitaxel 💬
| Paclitaxel | 046 [2] 46, 85 💬
|
75 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
IL1B [3] IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
76 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
77 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
78 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
79 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
80 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
81 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
82 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
83 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
84 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
85 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
86 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
CCN2 [1] CCN2 💬
|
Pamrevlumab Pamrevlumab 💬
| Pamrevlumab | 085 [2] 85, 113 💬
|
87 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
88 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
89 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
90 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
91 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
92 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
93 | Arachidonic acid metabolism 💬 4 genes, 26 drugs (DrugBank) and 43 diseases |
ALOX5 [1] ALOX5 💬
|
Zileuton Zileuton 💬
| Zileuton | 085 [3] 85, 160, 164 💬
|
94 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
IL10 [2] IL10, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
95 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
IL13 [1] IL13 💬
|
Lebrikizumab Lebrikizumab 💬
| Lebrikizumab | 085 [1] 85 💬
|
96 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
IL13 [1] IL13 💬
|
Tralokinumab Tralokinumab 💬
| Tralokinumab | 085 [2] 85, 97 💬
|
97 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
98 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
99 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
100 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
101 | Autoimmune thyroid disease 💬 22 genes, 15 drugs (DrugBank) and 35 diseases |
IL10 [1] IL10 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
102 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
103 | Autophagy - other 💬 1 gene, 3 drugs (DrugBank) and 41 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
104 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
ABL1 [1] ABL1 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
105 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
ABL1 [4] ABL1, EPHA2, FYN, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
106 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
ABL1 [4] ABL1, EPHA2, FYN, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
107 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
108 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
109 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
110 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
SMO [1] SMO 💬
|
Taladegib Taladegib 💬
| Taladegib | 085 [1] 85 💬
|
111 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
SMO [1] SMO 💬
|
Vismodegib Vismodegib 💬
| Vismodegib | 085 [1] 85 💬
|
112 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
113 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
114 | Bacterial invasion of epithelial cells 💬 5 genes, 7 drugs (DrugBank) and 13 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
115 | Bacterial invasion of epithelial cells 💬 5 genes, 7 drugs (DrugBank) and 13 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
116 | Basal cell carcinoma 💬 1 gene, 2 drugs (DrugBank) and 1 disease |
SMO [1] SMO 💬
|
Taladegib Taladegib 💬
| Taladegib | 085 [1] 85 💬
|
117 | Basal cell carcinoma 💬 1 gene, 2 drugs (DrugBank) and 1 disease |
SMO [1] SMO 💬
|
Vismodegib Vismodegib 💬
| Vismodegib | 085 [1] 85 💬
|
118 | beta-Alanine metabolism 💬 4 genes, 3 drugs (DrugBank) and 17 diseases |
ABAT [3] ABAT, GAD1, GAD2 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
119 | Biosynthesis of cofactors 💬 10 genes, 10 drugs (DrugBank) and 51 diseases |
NQO1 [2] NQO1, VKORC1 💬
|
Warfarin Warfarin 💬
| Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
|
120 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
FGFR3 [1] FGFR3 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
121 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
122 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
123 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
124 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
FGFR1 [2] FGFR1, FLT4 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
125 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
KIT [1] KIT 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
126 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
KIT [1] KIT 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
127 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
KIT [1] KIT 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
128 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
129 | Butanoate metabolism 💬 4 genes, 2 drugs (DrugBank) and 16 diseases |
ABAT [4] ABAT, ALDH5A1, GAD1, GAD2 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
130 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL10 [4] IL10, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
131 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
132 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
133 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
134 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
135 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
136 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
137 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
138 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
139 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRB1 [1] ADRB1 💬
|
Nebivolol Nebivolol 💬
| Nebivolol | 017 [4] 17, 85, 113, 167 💬
|
140 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRB2 [1] ADRB2 💬
|
Formoterol Formoterol 💬
| Formoterol | 085 [3] 85, 228, 299 💬
|
141 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRB2 [1] ADRB2 💬
|
Albuterol Albuterol 💬
| Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
|
142 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
143 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
144 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CYSLTR1 [1] CYSLTR1 💬
|
Montelukast Montelukast 💬
| Montelukast | 006 [8] 6 , 13, 46, 61, 63, 85, 98, 228 💬
|
145 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CYSLTR1 [1] CYSLTR1 💬
|
Tipelukast Tipelukast 💬
| Tipelukast | 085 [1] 85 💬
|
146 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EDNRA [1] EDNRA 💬
|
Ambrisentan Ambrisentan 💬
| Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬
|
147 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EDNRA [2] EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
148 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EDNRA [2] EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
149 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EDNRA [2] EDNRA, EDNRB 💬
|
Macitentan Macitentan 💬
| Macitentan | 051 [5] 51, 85, 86, 88, 210 💬
|
150 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
FGFR1 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
151 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
152 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
P2RX3 [1] P2RX3 💬
|
Gefapixant Gefapixant 💬
| Gefapixant | 085 [2] 85, 226 💬
|
153 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
154 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PDGFRB [1] PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
155 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PDGFRB [1] PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
156 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
157 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
158 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
TACR1 [1] TACR1 💬
|
Orvepitant Orvepitant 💬
| Orvepitant | 085 [1] 85 💬
|
159 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
TBXA2R [1] TBXA2R 💬
|
Ifetroban Ifetroban 💬
| Ifetroban | 085 [2] 85, 113 💬
|
160 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
161 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB1 [1] ADRB1 💬
|
Nebivolol Nebivolol 💬
| Nebivolol | 017 [4] 17, 85, 113, 167 💬
|
162 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB2 [1] ADRB2 💬
|
Formoterol Formoterol 💬
| Formoterol | 085 [3] 85, 228, 299 💬
|
163 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB2 [1] ADRB2 💬
|
Albuterol Albuterol 💬
| Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
|
164 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
EDNRA [1] EDNRA 💬
|
Ambrisentan Ambrisentan 💬
| Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬
|
165 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
EDNRA [1] EDNRA 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
166 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
EDNRA [1] EDNRA 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
167 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
EDNRA [1] EDNRA 💬
|
Macitentan Macitentan 💬
| Macitentan | 051 [5] 51, 85, 86, 88, 210 💬
|
168 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
169 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
170 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
SSTR2 [1] SSTR2 💬
|
Octreotide Octreotide 💬
| Octreotide | 067 [7] 67, 75, 84, 85, 89, 193, 227 💬
|
171 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
CD274 [1] CD274 💬
|
Atezolizumab Atezolizumab 💬
| Atezolizumab | 085 [1] 85 💬
|
172 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
CD274 [1] CD274 💬
|
Durvalumab Durvalumab 💬
| Durvalumab | 085 [1] 85 💬
|
173 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
PDCD1 [1] PDCD1 💬
|
Nivolumab Nivolumab 💬
| Nivolumab | 013 [12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
|
174 | Cell cycle 💬 10 genes, 9 drugs (DrugBank) and 21 diseases |
ABL1 [1] ABL1 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
175 | Cell cycle 💬 10 genes, 9 drugs (DrugBank) and 21 diseases |
ABL1 [1] ABL1 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
176 | Cell cycle 💬 10 genes, 9 drugs (DrugBank) and 21 diseases |
ABL1 [1] ABL1 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
177 | Cell cycle 💬 10 genes, 9 drugs (DrugBank) and 21 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
178 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
IL1A [2] IL1A, IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
179 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
IL6 [1] IL6 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
180 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
181 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
182 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
183 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
184 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
FGFR1 [5] FGFR1, FGFR2, FGFR3, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
185 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
KIT [2] KIT, PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
186 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
KIT [2] KIT, PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
187 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
KIT [2] KIT, PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
188 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
189 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRB1 [1] ADRB1 💬
|
Nebivolol Nebivolol 💬
| Nebivolol | 017 [4] 17, 85, 113, 167 💬
|
190 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRB2 [1] ADRB2 💬
|
Formoterol Formoterol 💬
| Formoterol | 085 [3] 85, 228, 299 💬
|
191 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRB2 [1] ADRB2 💬
|
Albuterol Albuterol 💬
| Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
|
192 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
193 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
EDNRA [1] EDNRA 💬
|
Ambrisentan Ambrisentan 💬
| Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬
|
194 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
EDNRA [2] EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
195 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
EDNRA [2] EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
196 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
EDNRA [2] EDNRA, EDNRB 💬
|
Macitentan Macitentan 💬
| Macitentan | 051 [5] 51, 85, 86, 88, 210 💬
|
197 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
OPRD1 [1] OPRD1 💬
|
Nalbuphine Nalbuphine 💬
| Nalbuphine | 085 [1] 85 💬
|
198 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PDE5A [1] PDE5A 💬
|
Sildenafil Sildenafil 💬
| Sildenafil | 006 [17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
|
199 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
200 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
201 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
202 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
CCL2 [5] CCL2, IL10, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
203 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
204 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
205 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
206 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
207 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
208 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
209 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
ABL1 [1] ABL1 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
210 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
ABL1 [2] ABL1, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
211 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
ABL1 [2] ABL1, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
212 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
NQO1 [1] NQO1 💬
|
Warfarin Warfarin 💬
| Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
|
213 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
214 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB1 [1] ADRB1 💬
|
Nebivolol Nebivolol 💬
| Nebivolol | 017 [4] 17, 85, 113, 167 💬
|
215 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB2 [1] ADRB2 💬
|
Formoterol Formoterol 💬
| Formoterol | 085 [3] 85, 228, 299 💬
|
216 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB2 [1] ADRB2 💬
|
Albuterol Albuterol 💬
| Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
|
217 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
AR [1] AR 💬
|
Nandrolone Nandrolone 💬
| Nandrolone | 060 [2] 60, 85 💬
|
218 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
AR [1] AR 💬
|
Nandrolone decanoate Nandrolone decanoate 💬
| Nandrolone decanoate | 060 [2] 60, 85 💬
|
219 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
220 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
221 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
222 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
VDR [1] VDR 💬
|
Cholecalciferol Cholecalciferol 💬
| Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
|
223 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
VDR [1] VDR 💬
|
Dihydrotachysterol Dihydrotachysterol 💬
| Dihydrotachysterol | 006 [2] 6 , 85 💬
|
224 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
225 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
CCL2 [1] CCL2 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
226 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
227 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
228 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
229 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
230 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
231 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
232 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
PDGFRB [1] PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
233 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
PDGFRB [1] PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
234 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
FYN [1] FYN 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
235 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
FYN [1] FYN 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
236 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
ABL1 [1] ABL1 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
237 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
ABL1 [1] ABL1 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
238 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
ABL1 [1] ABL1 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
239 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
240 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
241 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
242 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
243 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 35 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Lansoprazole Lansoprazole 💬
| Lansoprazole | 063 [7] 63, 71, 85, 98, 166, 222, 299 💬
|
244 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 35 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Omeprazole Omeprazole 💬
| Omeprazole | 006 [14] 6 , 8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
|
245 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
246 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
247 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
F2 [1] F2 💬
|
Dabigatran Dabigatran 💬
| Dabigatran | 051 [5] 51, 75, 85, 91, 124 💬
|
248 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
F2 [1] F2 💬
|
Thrombomodulin alfa Thrombomodulin alfa 💬
| Thrombomodulin Alfa | 085 [1] 85 💬
|
249 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
250 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
251 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
F2 [1] F2 💬
|
Dabigatran Dabigatran 💬
| Dabigatran | 051 [5] 51, 75, 85, 91, 124 💬
|
252 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
F2 [1] F2 💬
|
Thrombomodulin alfa Thrombomodulin alfa 💬
| Thrombomodulin Alfa | 085 [1] 85 💬
|
253 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
254 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
255 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
256 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
257 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
258 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
259 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
260 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
261 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CCL2 [6] CCL2, IL10, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
262 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CSF3R [1] CSF3R 💬
|
Filgrastim Filgrastim 💬
| Filgrastim | 002 [35] 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
|
263 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
264 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL13 [1] IL13 💬
|
Lebrikizumab Lebrikizumab 💬
| Lebrikizumab | 085 [1] 85 💬
|
265 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL13 [1] IL13 💬
|
Tralokinumab Tralokinumab 💬
| Tralokinumab | 085 [2] 85, 97 💬
|
266 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
267 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
LTA [2] LTA, TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
268 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
269 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
270 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
271 | Cytosolic DNA-sensing pathway 💬 17 genes, 12 drugs (DrugBank) and 28 diseases |
IL1B [2] IL1B, IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
272 | Cytosolic DNA-sensing pathway 💬 17 genes, 12 drugs (DrugBank) and 28 diseases |
IL6 [1] IL6 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
273 | Diabetic cardiomyopathy 💬 26 genes, 42 drugs (DrugBank) and 73 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
274 | Diabetic cardiomyopathy 💬 26 genes, 42 drugs (DrugBank) and 73 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
275 | Diabetic cardiomyopathy 💬 26 genes, 42 drugs (DrugBank) and 73 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
276 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
ADRB1 [1] ADRB1 💬
|
Nebivolol Nebivolol 💬
| Nebivolol | 017 [4] 17, 85, 113, 167 💬
|
277 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
278 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
279 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
280 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
281 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
282 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
283 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
284 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
PPP3CA [3] PPP3CA, PPP3CB, PPP3CC 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
285 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
PPP3CA [3] PPP3CA, PPP3CB, PPP3CC 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
286 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 48 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬
|
Mycophenolate mofetil Mycophenolate mofetil 💬
| Mycophenolate mofetil | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
|
287 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 48 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬
|
Mycophenolic acid Mycophenolic acid 💬
| Mycophenolic acid | 002 [36] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
|
288 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 48 diseases |
RRM1 [1] RRM1 💬
|
Fludarabine Fludarabine 💬
| Fludarabine | 011 [20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬
|
289 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 48 diseases |
RRM2 [1] RRM2 💬
|
Hydroxyurea Hydroxyurea 💬
| Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬
|
290 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
FGFR2 [5] FGFR2, FGFR3, KDR, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
291 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
IL6 [1] IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
292 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
IL6 [1] IL6 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
293 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
294 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
295 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
PDGFRB [2] PDGFRB, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
296 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
PDGFRB [2] PDGFRB, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
297 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
298 | Endocrine and other factor-regulated calcium reabsorption 💬 8 genes, 27 drugs (DrugBank) and 55 diseases |
VDR [1] VDR 💬
|
Cholecalciferol Cholecalciferol 💬
| Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
|
299 | Endocrine and other factor-regulated calcium reabsorption 💬 8 genes, 27 drugs (DrugBank) and 55 diseases |
VDR [1] VDR 💬
|
Dihydrotachysterol Dihydrotachysterol 💬
| Dihydrotachysterol | 006 [2] 6 , 85 💬
|
300 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
301 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
302 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
303 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
FGFR2 [3] FGFR2, FGFR3, PDGFRA 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
304 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
305 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
306 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
307 | Epithelial cell signaling in Helicobacter pylori infection 💬 12 genes, 17 drugs (DrugBank) and 21 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
308 | Epithelial cell signaling in Helicobacter pylori infection 💬 12 genes, 17 drugs (DrugBank) and 21 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
309 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
IL6 [2] IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
310 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
311 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
312 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
313 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
314 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
ABL1 [1] ABL1 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
315 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
ABL1 [2] ABL1, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
316 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
ABL1 [2] ABL1, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
317 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
318 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
OPRM1 [1] OPRM1 💬
|
Morphine Morphine 💬
| Morphine | 036 [5] 36, 46, 70, 85, 86 💬
|
319 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
OPRM1 [1] OPRM1 💬
|
Nalbuphine Nalbuphine 💬
| Nalbuphine | 085 [1] 85 💬
|
320 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
321 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
322 | Ether lipid metabolism 💬 1 gene, 1 drug (DrugBank) and 2 diseases |
ENPP2 [1] ENPP2 💬
|
Ziritaxestat Ziritaxestat 💬
| Ziritaxestat | 051 [2] 51, 85 💬
|
323 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
ALOX5 [1] ALOX5 💬
|
Zileuton Zileuton 💬
| Zileuton | 085 [3] 85, 160, 164 💬
|
324 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
FYN [1] FYN 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
325 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
FYN [1] FYN 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
326 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
IL13 [1] IL13 💬
|
Lebrikizumab Lebrikizumab 💬
| Lebrikizumab | 085 [1] 85 💬
|
327 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
IL13 [1] IL13 💬
|
Tralokinumab Tralokinumab 💬
| Tralokinumab | 085 [2] 85, 97 💬
|
328 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
329 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
330 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
331 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
332 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
333 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
CCL2 [4] CCL2, IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
334 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
KDR [1] KDR 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
335 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
NQO1 [1] NQO1 💬
|
Warfarin Warfarin 💬
| Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
|
336 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
337 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
338 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
339 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
340 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
341 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
342 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
343 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
FLT1 [5] FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
344 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
FYN [3] FYN, PDGFRB, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
345 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
FYN [3] FYN, PDGFRB, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
346 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
347 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
348 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
349 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
IL10 [2] IL10, IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
350 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
IL6 [1] IL6 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
351 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
352 | GABAergic synapse 💬 29 genes, 38 drugs (DrugBank) and 55 diseases |
ABAT [3] ABAT, GAD1, GAD2 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
353 | GABAergic synapse 💬 29 genes, 38 drugs (DrugBank) and 55 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
354 | GABAergic synapse 💬 29 genes, 38 drugs (DrugBank) and 55 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
355 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
ADRB1 [1] ADRB1 💬
|
Nebivolol Nebivolol 💬
| Nebivolol | 017 [4] 17, 85, 113, 167 💬
|
356 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
357 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
358 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
PDGFRB [2] PDGFRB, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
359 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
PDGFRB [2] PDGFRB, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
360 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Paclitaxel Paclitaxel 💬
| Paclitaxel | 046 [2] 46, 85 💬
|
361 | Gastric acid secretion 💬 14 genes, 43 drugs (DrugBank) and 52 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Lansoprazole Lansoprazole 💬
| Lansoprazole | 063 [7] 63, 71, 85, 98, 166, 222, 299 💬
|
362 | Gastric acid secretion 💬 14 genes, 43 drugs (DrugBank) and 52 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Omeprazole Omeprazole 💬
| Omeprazole | 006 [14] 6 , 8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
|
363 | Gastric acid secretion 💬 14 genes, 43 drugs (DrugBank) and 52 diseases |
SSTR2 [1] SSTR2 💬
|
Octreotide Octreotide 💬
| Octreotide | 067 [7] 67, 75, 84, 85, 89, 193, 227 💬
|
364 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
FGFR2 [1] FGFR2 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
365 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
366 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
367 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
368 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
369 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
370 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
PDGFRB [1] PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
371 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
PDGFRB [1] PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
372 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
373 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
374 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
375 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
376 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
377 | Glutathione metabolism 💬 4 genes, 6 drugs (DrugBank) and 25 diseases |
RRM1 [1] RRM1 💬
|
Fludarabine Fludarabine 💬
| Fludarabine | 011 [20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬
|
378 | Glutathione metabolism 💬 4 genes, 6 drugs (DrugBank) and 25 diseases |
RRM2 [1] RRM2 💬
|
Hydroxyurea Hydroxyurea 💬
| Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬
|
379 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
380 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
381 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
382 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
IL1A [4] IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
383 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
384 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
385 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
386 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
387 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
388 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
SSTR2 [1] SSTR2 💬
|
Octreotide Octreotide 💬
| Octreotide | 067 [7] 67, 75, 84, 85, 89, 193, 227 💬
|
389 | Hedgehog signaling pathway 💬 2 genes, 3 drugs (DrugBank) and 2 diseases |
SMO [1] SMO 💬
|
Taladegib Taladegib 💬
| Taladegib | 085 [1] 85 💬
|
390 | Hedgehog signaling pathway 💬 2 genes, 3 drugs (DrugBank) and 2 diseases |
SMO [1] SMO 💬
|
Vismodegib Vismodegib 💬
| Vismodegib | 085 [1] 85 💬
|
391 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
CSF3R [1] CSF3R 💬
|
Filgrastim Filgrastim 💬
| Filgrastim | 002 [35] 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
|
392 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL1A [4] IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
393 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
394 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
KIT [1] KIT 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
395 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
KIT [1] KIT 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
396 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
KIT [1] KIT 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
397 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
MS4A1 [1] MS4A1 💬
|
Rituximab Rituximab 💬
| Rituximab | 011 [48] 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
|
398 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
399 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
400 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
401 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
IL6 [2] IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
402 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
403 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
404 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
405 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
406 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
407 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
408 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
409 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
410 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
411 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
412 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
413 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
414 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
415 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
NQO1 [1] NQO1 💬
|
Warfarin Warfarin 💬
| Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
|
416 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
417 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
418 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
419 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
420 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
LTA [2] LTA, TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
421 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
422 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
423 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
424 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
425 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
426 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
FLT1 [1] FLT1 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
427 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
428 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
IL6 [1] IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
429 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
IL6 [1] IL6 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
430 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
431 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
432 | Hippo signaling pathway 💬 5 genes, 3 drugs (DrugBank) and 6 diseases |
CCN2 [1] CCN2 💬
|
Pamrevlumab Pamrevlumab 💬
| Pamrevlumab | 085 [2] 85, 113 💬
|
433 | Hippo signaling pathway 💬 5 genes, 3 drugs (DrugBank) and 6 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
434 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
435 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
436 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
437 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
438 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PDGFRA [1] PDGFRA 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
439 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
440 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
441 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
442 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
443 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
444 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
445 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
446 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
447 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
448 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
449 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
450 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
451 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
452 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
453 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
454 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
455 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
456 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
457 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
PDGFRB [1] PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
458 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
PDGFRB [1] PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
459 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
PDGFRB [1] PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
460 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
461 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
462 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
463 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
464 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
465 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
466 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
IL6 [2] IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
467 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
468 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
LCK [1] LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
469 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
LCK [1] LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
470 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
LTA [2] LTA, TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
471 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
472 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
473 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
474 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
475 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
476 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
GRIN1 [2] GRIN1, GRIN2B 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
477 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
478 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Paclitaxel Paclitaxel 💬
| Paclitaxel | 046 [2] 46, 85 💬
|
479 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
IL6 [2] IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
480 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
481 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
482 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
483 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
484 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
485 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
486 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL13 [1] IL13 💬
|
Lebrikizumab Lebrikizumab 💬
| Lebrikizumab | 085 [1] 85 💬
|
487 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL13 [1] IL13 💬
|
Tralokinumab Tralokinumab 💬
| Tralokinumab | 085 [2] 85, 97 💬
|
488 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
489 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
490 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
491 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
492 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
493 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL10 [5] IL10, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
494 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL13 [1] IL13 💬
|
Lebrikizumab Lebrikizumab 💬
| Lebrikizumab | 085 [1] 85 💬
|
495 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL13 [1] IL13 💬
|
Tralokinumab Tralokinumab 💬
| Tralokinumab | 085 [2] 85, 97 💬
|
496 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
497 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
498 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
499 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
500 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
501 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
IL1B [1] IL1B 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
502 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
503 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
504 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
CCL2 [5] CCL2, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
505 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
506 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
507 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
508 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
509 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
510 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
IL6 [2] IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
511 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
512 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
513 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
514 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
515 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
516 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
517 | Intestinal immune network for IgA production 💬 16 genes, 27 drugs (DrugBank) and 47 diseases |
IL10 [2] IL10, IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
518 | Intestinal immune network for IgA production 💬 16 genes, 27 drugs (DrugBank) and 47 diseases |
IL6 [1] IL6 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
519 | Intestinal immune network for IgA production 💬 16 genes, 27 drugs (DrugBank) and 47 diseases |
TGFB1 [1] TGFB1 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
520 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
CSF3R [1] CSF3R 💬
|
Filgrastim Filgrastim 💬
| Filgrastim | 002 [35] 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
|
521 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
522 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL10 [2] IL10, IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
523 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL13 [1] IL13 💬
|
Lebrikizumab Lebrikizumab 💬
| Lebrikizumab | 085 [1] 85 💬
|
524 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL13 [1] IL13 💬
|
Tralokinumab Tralokinumab 💬
| Tralokinumab | 085 [2] 85, 97 💬
|
525 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL6 [1] IL6 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
526 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
527 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
528 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
529 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
PDGFRB [1] PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
530 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
PDGFRB [1] PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
531 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
IFNGR1 [1] IFNGR1 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
532 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
IL6 [1] IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
533 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
IL6 [1] IL6 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
534 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
535 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
536 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
537 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
538 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
539 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
540 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
IL1B [3] IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
541 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
542 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
543 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
544 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
545 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
546 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
IL10 [4] IL10, IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
547 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
548 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
549 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
550 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
551 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
552 | Leukocyte transendothelial migration 💬 13 genes, 14 drugs (DrugBank) and 30 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
553 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
554 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
555 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
556 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
557 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
558 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
559 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
560 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
561 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
562 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
563 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
564 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
565 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
566 | Longevity regulating pathway 💬 11 genes, 20 drugs (DrugBank) and 68 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
567 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
568 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
CCL2 [5] CCL2, IL10, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
569 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
570 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
571 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
572 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
573 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
574 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
575 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
EPHA2 [3] EPHA2, KIT, PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
576 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
EPHA2 [3] EPHA2, KIT, PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
577 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
FGFR1 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
578 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IL1A [3] IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
579 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
KIT [2] KIT, PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
580 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
581 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
582 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
583 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
584 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
585 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
586 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
587 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
588 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL1A [3] IL1A, IL1B, IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
589 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL6 [1] IL6 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
590 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
EDNRB [1] EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
591 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
EDNRB [1] EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
592 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
EDNRB [1] EDNRB 💬
|
Macitentan Macitentan 💬
| Macitentan | 051 [5] 51, 85, 86, 88, 210 💬
|
593 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
KIT [1] KIT 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
594 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
KIT [1] KIT 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
595 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
KIT [1] KIT 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
596 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
FGFR1 [3] FGFR1, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
597 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
598 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
PDGFRB [1] PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
599 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
PDGFRB [1] PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
600 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ABAT [4] ABAT, ALDH5A1, GAD1, GAD2 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
601 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ALOX5 [1] ALOX5 💬
|
Zileuton Zileuton 💬
| Zileuton | 085 [3] 85, 160, 164 💬
|
602 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Lansoprazole Lansoprazole 💬
| Lansoprazole | 063 [7] 63, 71, 85, 98, 166, 222, 299 💬
|
603 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Omeprazole Omeprazole 💬
| Omeprazole | 006 [14] 6 , 8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
|
604 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ENPP2 [1] ENPP2 💬
|
Ziritaxestat Ziritaxestat 💬
| Ziritaxestat | 051 [2] 51, 85 💬
|
605 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬
|
Mycophenolate mofetil Mycophenolate mofetil 💬
| Mycophenolate mofetil | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
|
606 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬
|
Mycophenolic acid Mycophenolic acid 💬
| Mycophenolic acid | 002 [36] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
|
607 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
NQO1 [2] NQO1, VKORC1 💬
|
Warfarin Warfarin 💬
| Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
|
608 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE5A [1] PDE5A 💬
|
Sildenafil Sildenafil 💬
| Sildenafil | 006 [17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
|
609 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
RRM1 [1] RRM1 💬
|
Fludarabine Fludarabine 💬
| Fludarabine | 011 [20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬
|
610 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
RRM2 [1] RRM2 💬
|
Hydroxyurea Hydroxyurea 💬
| Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬
|
611 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
ABL1 [2] ABL1, PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
612 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
ABL1 [2] ABL1, PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
613 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
ABL1 [2] ABL1, PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
614 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
FGFR3 [3] FGFR3, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
615 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
616 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
TGFB2 [1] TGFB2 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
617 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
618 | Mineral absorption 💬 8 genes, 13 drugs (DrugBank) and 41 diseases |
VDR [1] VDR 💬
|
Cholecalciferol Cholecalciferol 💬
| Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
|
619 | Mineral absorption 💬 8 genes, 13 drugs (DrugBank) and 41 diseases |
VDR [1] VDR 💬
|
Dihydrotachysterol Dihydrotachysterol 💬
| Dihydrotachysterol | 006 [2] 6 , 85 💬
|
620 | Mitophagy - animal 💬 2 genes, 4 drugs (DrugBank) and 8 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
621 | Mitophagy - animal 💬 2 genes, 4 drugs (DrugBank) and 8 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
622 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
OPRM1 [1] OPRM1 💬
|
Morphine Morphine 💬
| Morphine | 036 [5] 36, 46, 70, 85, 86 💬
|
623 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
OPRM1 [1] OPRM1 💬
|
Nalbuphine Nalbuphine 💬
| Nalbuphine | 085 [1] 85 💬
|
624 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
625 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
626 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
627 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
628 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
629 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
630 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
FYN [2] FYN, LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
631 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
FYN [2] FYN, LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
632 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
633 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
634 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
635 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
636 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
637 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
638 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
639 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
640 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
641 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IL1A [3] IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
642 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
643 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
644 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
645 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
646 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRB1 [1] ADRB1 💬
|
Nebivolol Nebivolol 💬
| Nebivolol | 017 [4] 17, 85, 113, 167 💬
|
647 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRB2 [1] ADRB2 💬
|
Formoterol Formoterol 💬
| Formoterol | 085 [3] 85, 228, 299 💬
|
648 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRB2 [1] ADRB2 💬
|
Albuterol Albuterol 💬
| Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
|
649 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
650 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CYSLTR1 [1] CYSLTR1 💬
|
Montelukast Montelukast 💬
| Montelukast | 006 [8] 6 , 13, 46, 61, 63, 85, 98, 228 💬
|
651 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CYSLTR1 [1] CYSLTR1 💬
|
Tipelukast Tipelukast 💬
| Tipelukast | 085 [1] 85 💬
|
652 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
EDNRA [1] EDNRA 💬
|
Ambrisentan Ambrisentan 💬
| Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬
|
653 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
EDNRA [2] EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
654 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
EDNRA [2] EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
655 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
EDNRA [2] EDNRA, EDNRB 💬
|
Macitentan Macitentan 💬
| Macitentan | 051 [5] 51, 85, 86, 88, 210 💬
|
656 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
F2 [1] F2 💬
|
Dabigatran Dabigatran 💬
| Dabigatran | 051 [5] 51, 75, 85, 91, 124 💬
|
657 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
F2 [1] F2 💬
|
Thrombomodulin alfa Thrombomodulin alfa 💬
| Thrombomodulin Alfa | 085 [1] 85 💬
|
658 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
659 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Beclomethasone dipropionate Beclomethasone dipropionate 💬
| Beclomethasone dipropionate | 085 [3] 85, 97, 98 💬
|
660 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Methylprednisolone Methylprednisolone 💬
| Methylprednisolone | 002 [46] 2 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
|
661 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Prednisolone Prednisolone 💬
| Prednisolone | 003 [42] 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
|
662 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Prednisone Prednisone 💬
| Prednisone | 002 [45] 2 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬
|
663 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
OPRD1 [3] OPRD1, OPRK1, OPRM1 💬
|
Nalbuphine Nalbuphine 💬
| Nalbuphine | 085 [1] 85 💬
|
664 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
OPRM1 [1] OPRM1 💬
|
Morphine Morphine 💬
| Morphine | 036 [5] 36, 46, 70, 85, 86 💬
|
665 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
P2RX3 [1] P2RX3 💬
|
Gefapixant Gefapixant 💬
| Gefapixant | 085 [2] 85, 226 💬
|
666 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
PTGIR [1] PTGIR 💬
|
Iloprost Iloprost 💬
| Iloprost | 051 [4] 51, 84, 85, 86 💬
|
667 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
PTGIR [1] PTGIR 💬
|
Treprostinil Treprostinil 💬
| Treprostinil | 051 [6] 51, 84, 85, 86, 88, 210 💬
|
668 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
SSTR2 [1] SSTR2 💬
|
Octreotide Octreotide 💬
| Octreotide | 067 [7] 67, 75, 84, 85, 89, 193, 227 💬
|
669 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
TACR1 [1] TACR1 💬
|
Orvepitant Orvepitant 💬
| Orvepitant | 085 [1] 85 💬
|
670 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
TBXA2R [1] TBXA2R 💬
|
Ifetroban Ifetroban 💬
| Ifetroban | 085 [2] 85, 113 💬
|
671 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
ABL1 [1] ABL1 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
672 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
ABL1 [1] ABL1 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
673 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
ABL1 [1] ABL1 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
674 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
ELANE [1] ELANE 💬
|
Sivelestat Sivelestat 💬
| Sivelestat | 013 [3] 13, 85, 96 💬
|
675 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
676 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
677 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
678 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
IL1B [2] IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
679 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
LCK [1] LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
680 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
LCK [1] LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
681 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
LTA [2] LTA, TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
682 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
683 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
684 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
685 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
686 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
687 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
688 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
689 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
690 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
691 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL1A [4] IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
692 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
693 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TGFB1 [1] TGFB1 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
694 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
695 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
696 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
697 | Nucleotide metabolism 💬 7 genes, 12 drugs (DrugBank) and 46 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬
|
Mycophenolate mofetil Mycophenolate mofetil 💬
| Mycophenolate mofetil | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
|
698 | Nucleotide metabolism 💬 7 genes, 12 drugs (DrugBank) and 46 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬
|
Mycophenolic acid Mycophenolic acid 💬
| Mycophenolic acid | 002 [36] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
|
699 | Nucleotide metabolism 💬 7 genes, 12 drugs (DrugBank) and 46 diseases |
RRM1 [1] RRM1 💬
|
Fludarabine Fludarabine 💬
| Fludarabine | 011 [20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬
|
700 | Nucleotide metabolism 💬 7 genes, 12 drugs (DrugBank) and 46 diseases |
RRM2 [1] RRM2 💬
|
Hydroxyurea Hydroxyurea 💬
| Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬
|
701 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
AR [1] AR 💬
|
Nandrolone Nandrolone 💬
| Nandrolone | 060 [2] 60, 85 💬
|
702 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
AR [1] AR 💬
|
Nandrolone decanoate Nandrolone decanoate 💬
| Nandrolone decanoate | 060 [2] 60, 85 💬
|
703 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
704 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
705 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
FYN [2] FYN, LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
706 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
FYN [2] FYN, LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
707 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
708 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IL1A [3] IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
709 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
710 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
711 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TGFB1 [2] TGFB1, TGFB2 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
712 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
713 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
714 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
715 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
716 | Ovarian steroidogenesis 💬 7 genes, 36 drugs (DrugBank) and 52 diseases |
ALOX5 [1] ALOX5 💬
|
Zileuton Zileuton 💬
| Zileuton | 085 [3] 85, 160, 164 💬
|
717 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 25 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Lansoprazole Lansoprazole 💬
| Lansoprazole | 063 [7] 63, 71, 85, 98, 166, 222, 299 💬
|
718 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 25 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Omeprazole Omeprazole 💬
| Omeprazole | 006 [14] 6 , 8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
|
719 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
720 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
721 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
722 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
723 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
724 | p53 signaling pathway 💬 5 genes, 4 drugs (DrugBank) and 13 diseases |
RRM2 [1] RRM2 💬
|
Hydroxyurea Hydroxyurea 💬
| Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬
|
725 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
726 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
727 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
728 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
FGFR1 [1] FGFR1 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
729 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
VDR [1] VDR 💬
|
Cholecalciferol Cholecalciferol 💬
| Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
|
730 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
VDR [1] VDR 💬
|
Dihydrotachysterol Dihydrotachysterol 💬
| Dihydrotachysterol | 006 [2] 6 , 85 💬
|
731 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Paclitaxel Paclitaxel 💬
| Paclitaxel | 046 [2] 46, 85 💬
|
732 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
ABL1 [1] ABL1 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
733 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
ABL1 [3] ABL1, FYN, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
734 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
ABL1 [3] ABL1, FYN, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
735 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
F2 [1] F2 💬
|
Dabigatran Dabigatran 💬
| Dabigatran | 051 [5] 51, 75, 85, 91, 124 💬
|
736 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
F2 [1] F2 💬
|
Thrombomodulin alfa Thrombomodulin alfa 💬
| Thrombomodulin Alfa | 085 [1] 85 💬
|
737 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
IL1B [3] IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
738 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
739 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
740 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
741 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
742 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
743 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Paclitaxel Paclitaxel 💬
| Paclitaxel | 046 [2] 46, 85 💬
|
744 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ABL1 [3] ABL1, KIT, PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
745 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ABL1 [3] ABL1, KIT, PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
746 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ABL1 [3] ABL1, KIT, PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
747 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
748 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AR [1] AR 💬
|
Nandrolone Nandrolone 💬
| Nandrolone | 060 [2] 60, 85 💬
|
749 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AR [1] AR 💬
|
Nandrolone decanoate Nandrolone decanoate 💬
| Nandrolone decanoate | 060 [2] 60, 85 💬
|
750 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
CSF3R [1] CSF3R 💬
|
Filgrastim Filgrastim 💬
| Filgrastim | 002 [35] 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
|
751 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EDNRA [1] EDNRA 💬
|
Ambrisentan Ambrisentan 💬
| Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬
|
752 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EDNRA [2] EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
753 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EDNRA [2] EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
754 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EDNRA [2] EDNRA, EDNRB 💬
|
Macitentan Macitentan 💬
| Macitentan | 051 [5] 51, 85, 86, 88, 210 💬
|
755 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
F2 [1] F2 💬
|
Dabigatran Dabigatran 💬
| Dabigatran | 051 [5] 51, 75, 85, 91, 124 💬
|
756 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
F2 [1] F2 💬
|
Thrombomodulin alfa Thrombomodulin alfa 💬
| Thrombomodulin Alfa | 085 [1] 85 💬
|
757 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
FGFR1 [6] FGFR1, FGFR2, FGFR3, FLT4, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
758 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
759 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL13 [1] IL13 💬
|
Lebrikizumab Lebrikizumab 💬
| Lebrikizumab | 085 [1] 85 💬
|
760 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL13 [1] IL13 💬
|
Tralokinumab Tralokinumab 💬
| Tralokinumab | 085 [2] 85, 97 💬
|
761 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL6 [1] IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
762 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL6 [1] IL6 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
763 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
764 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
NQO1 [1] NQO1 💬
|
Warfarin Warfarin 💬
| Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
|
765 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
766 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
SMO [1] SMO 💬
|
Taladegib Taladegib 💬
| Taladegib | 085 [1] 85 💬
|
767 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
SMO [1] SMO 💬
|
Vismodegib Vismodegib 💬
| Vismodegib | 085 [1] 85 💬
|
768 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
769 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
770 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
GRIN1 [6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
771 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
IL1A [4] IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
772 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
773 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
774 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
775 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
776 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
777 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
778 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
779 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Paclitaxel Paclitaxel 💬
| Paclitaxel | 046 [2] 46, 85 💬
|
780 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
CD274 [1] CD274 💬
|
Atezolizumab Atezolizumab 💬
| Atezolizumab | 085 [1] 85 💬
|
781 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
CD274 [1] CD274 💬
|
Durvalumab Durvalumab 💬
| Durvalumab | 085 [1] 85 💬
|
782 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
783 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
LCK [1] LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
784 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
LCK [1] LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
785 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
786 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
PDCD1 [1] PDCD1 💬
|
Nivolumab Nivolumab 💬
| Nivolumab | 013 [12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
|
787 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
788 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
789 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL10 [5] IL10, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
790 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
791 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
792 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
793 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
794 | Phagosome 💬 13 genes, 10 drugs (DrugBank) and 21 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Paclitaxel Paclitaxel 💬
| Paclitaxel | 046 [2] 46, 85 💬
|
795 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
796 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
F2 [1] F2 💬
|
Dabigatran Dabigatran 💬
| Dabigatran | 051 [5] 51, 75, 85, 91, 124 💬
|
797 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
F2 [1] F2 💬
|
Thrombomodulin alfa Thrombomodulin alfa 💬
| Thrombomodulin Alfa | 085 [1] 85 💬
|
798 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
FYN [3] FYN, KIT, PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
799 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
FYN [3] FYN, KIT, PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
800 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
KIT [2] KIT, PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
801 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
802 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
803 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CSF3R [1] CSF3R 💬
|
Filgrastim Filgrastim 💬
| Filgrastim | 002 [35] 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
|
804 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
EPHA2 [3] EPHA2, KIT, PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
805 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
EPHA2 [3] EPHA2, KIT, PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
806 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
FGFR1 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
807 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL6 [1] IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
808 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL6 [1] IL6 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
809 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
KIT [2] KIT, PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
810 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
811 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
812 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
F2 [1] F2 💬
|
Dabigatran Dabigatran 💬
| Dabigatran | 051 [5] 51, 75, 85, 91, 124 💬
|
813 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
F2 [1] F2 💬
|
Thrombomodulin alfa Thrombomodulin alfa 💬
| Thrombomodulin Alfa | 085 [1] 85 💬
|
814 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
FYN [2] FYN, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
815 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
FYN [2] FYN, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
816 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
P2RY12 [1] P2RY12 💬
|
Ticagrelor Ticagrelor 💬
| Ticagrelor | 036 [3] 36, 46, 85 💬
|
817 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PTGIR [1] PTGIR 💬
|
Iloprost Iloprost 💬
| Iloprost | 051 [4] 51, 84, 85, 86 💬
|
818 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PTGIR [1] PTGIR 💬
|
Treprostinil Treprostinil 💬
| Treprostinil | 051 [6] 51, 84, 85, 86, 88, 210 💬
|
819 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
820 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
TBXA2R [1] TBXA2R 💬
|
Ifetroban Ifetroban 💬
| Ifetroban | 085 [2] 85, 113 💬
|
821 | Platinum drug resistance 💬 9 genes, 15 drugs (DrugBank) and 23 diseases |
TOP2A [2] TOP2A, TOP2B 💬
|
Etoposide Etoposide 💬
| Etoposide | 011 [11] 11, 13, 14, 26, 28, 34, 60, 65, 85, 164, 331 💬
|
822 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
LCK [1] LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
823 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
LCK [1] LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
824 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
FYN [1] FYN 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
825 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
FYN [1] FYN 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
826 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
827 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
IL1A [4] IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
828 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
829 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
830 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
831 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
832 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
833 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
834 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Paclitaxel Paclitaxel 💬
| Paclitaxel | 046 [2] 46, 85 💬
|
835 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
836 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
837 | Propanoate metabolism 💬 1 gene, 2 drugs (DrugBank) and 16 diseases |
ABAT [1] ABAT 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
838 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
AR [1] AR 💬
|
Nandrolone Nandrolone 💬
| Nandrolone | 060 [2] 60, 85 💬
|
839 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
AR [1] AR 💬
|
Nandrolone decanoate Nandrolone decanoate 💬
| Nandrolone decanoate | 060 [2] 60, 85 💬
|
840 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
FGFR1 [4] FGFR1, FGFR2, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
841 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
842 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
843 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
PDGFRB [1] PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
844 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
PDGFRB [1] PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
845 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
FGFR1 [2] FGFR1, KDR 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
846 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
847 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
848 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
SMO [1] SMO 💬
|
Taladegib Taladegib 💬
| Taladegib | 085 [1] 85 💬
|
849 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
SMO [1] SMO 💬
|
Vismodegib Vismodegib 💬
| Vismodegib | 085 [1] 85 💬
|
850 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
851 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
852 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TGFB1 [2] TGFB1, TGFB2 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
853 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
854 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
855 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
856 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
857 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
858 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
859 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬
|
Mycophenolate mofetil Mycophenolate mofetil 💬
| Mycophenolate mofetil | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
|
860 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬
|
Mycophenolic acid Mycophenolic acid 💬
| Mycophenolic acid | 002 [36] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
|
861 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE5A [1] PDE5A 💬
|
Sildenafil Sildenafil 💬
| Sildenafil | 006 [17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
|
862 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
RRM1 [1] RRM1 💬
|
Fludarabine Fludarabine 💬
| Fludarabine | 011 [20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬
|
863 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
RRM2 [1] RRM2 💬
|
Hydroxyurea Hydroxyurea 💬
| Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬
|
864 | Pyrimidine metabolism 💬 4 genes, 7 drugs (DrugBank) and 36 diseases |
RRM1 [1] RRM1 💬
|
Fludarabine Fludarabine 💬
| Fludarabine | 011 [20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬
|
865 | Pyrimidine metabolism 💬 4 genes, 7 drugs (DrugBank) and 36 diseases |
RRM2 [1] RRM2 💬
|
Hydroxyurea Hydroxyurea 💬
| Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬
|
866 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
EPHA2 [4] EPHA2, KIT, PDGFRB, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
867 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
EPHA2 [4] EPHA2, KIT, PDGFRB, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
868 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
FGFR1 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
869 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
870 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
KIT [2] KIT, PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
871 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
872 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
ABL1 [4] ABL1, EPHA2, KIT, PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
873 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
ABL1 [4] ABL1, EPHA2, KIT, PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
874 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
ABL1 [3] ABL1, KIT, PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
875 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
FGFR1 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
876 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
877 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
878 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
F2 [1] F2 💬
|
Dabigatran Dabigatran 💬
| Dabigatran | 051 [5] 51, 75, 85, 91, 124 💬
|
879 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
F2 [1] F2 💬
|
Thrombomodulin alfa Thrombomodulin alfa 💬
| Thrombomodulin Alfa | 085 [1] 85 💬
|
880 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
FGFR1 [5] FGFR1, FGFR2, FGFR3, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
881 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
882 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
PDGFRB [2] PDGFRB, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
883 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
PDGFRB [2] PDGFRB, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
884 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
885 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases |
ADRB1 [1] ADRB1 💬
|
Nebivolol Nebivolol 💬
| Nebivolol | 017 [4] 17, 85, 113, 167 💬
|
886 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases |
ADRB2 [1] ADRB2 💬
|
Formoterol Formoterol 💬
| Formoterol | 085 [3] 85, 228, 299 💬
|
887 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases |
ADRB2 [1] ADRB2 💬
|
Albuterol Albuterol 💬
| Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
|
888 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
EDNRB [1] EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
889 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
EDNRB [1] EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
890 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
EDNRB [1] EDNRB 💬
|
Macitentan Macitentan 💬
| Macitentan | 051 [5] 51, 85, 86, 88, 210 💬
|
891 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
892 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
893 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
TGFB1 [1] TGFB1 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
894 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
895 | Renal cell carcinoma 💬 12 genes, 15 drugs (DrugBank) and 19 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
896 | Renal cell carcinoma 💬 12 genes, 15 drugs (DrugBank) and 19 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
897 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
ADRB1 [1] ADRB1 💬
|
Nebivolol Nebivolol 💬
| Nebivolol | 017 [4] 17, 85, 113, 167 💬
|
898 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
ADRB2 [1] ADRB2 💬
|
Formoterol Formoterol 💬
| Formoterol | 085 [3] 85, 228, 299 💬
|
899 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
ADRB2 [1] ADRB2 💬
|
Albuterol Albuterol 💬
| Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
|
900 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
901 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
EDNRA [1] EDNRA 💬
|
Ambrisentan Ambrisentan 💬
| Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬
|
902 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
EDNRA [1] EDNRA 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
903 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
EDNRA [1] EDNRA 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
904 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
EDNRA [1] EDNRA 💬
|
Macitentan Macitentan 💬
| Macitentan | 051 [5] 51, 85, 86, 88, 210 💬
|
905 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
906 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
907 | Renin-angiotensin system 💬 6 genes, 21 drugs (DrugBank) and 31 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
908 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
CCL2 [5] CCL2, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
909 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
FLT1 [1] FLT1 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
910 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
911 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
912 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
913 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
914 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
915 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
916 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
917 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
918 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
919 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
920 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
921 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRB1 [1] ADRB1 💬
|
Nebivolol Nebivolol 💬
| Nebivolol | 017 [4] 17, 85, 113, 167 💬
|
922 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRB2 [1] ADRB2 💬
|
Formoterol Formoterol 💬
| Formoterol | 085 [3] 85, 228, 299 💬
|
923 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRB2 [1] ADRB2 💬
|
Albuterol Albuterol 💬
| Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
|
924 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
IL1B [3] IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
925 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
926 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
927 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
928 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
929 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
930 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Paclitaxel Paclitaxel 💬
| Paclitaxel | 046 [2] 46, 85 💬
|
931 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
ALOX5 [1] ALOX5 💬
|
Zileuton Zileuton 💬
| Zileuton | 085 [3] 85, 160, 164 💬
|
932 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
SLC6A4 [1] SLC6A4 💬
|
Paroxetine Paroxetine 💬
| Paroxetine | 006 [4] 6 , 13, 46, 85 💬
|
933 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
IL1B [2] IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
934 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
935 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
936 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
937 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
938 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
939 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
940 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
941 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
942 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
FGFR1 [3] FGFR1, FGFR2, FGFR3 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
943 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
FYN [1] FYN 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
944 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
FYN [1] FYN 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
945 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
OPRD1 [1] OPRD1 💬
|
Nalbuphine Nalbuphine 💬
| Nalbuphine | 085 [1] 85 💬
|
946 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
947 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
948 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
949 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
950 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
951 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
952 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
953 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
954 | Staphylococcus aureus infection 💬 12 genes, 19 drugs (DrugBank) and 34 diseases |
IL10 [1] IL10 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
955 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A4 [1] SLC6A4 💬
|
Paroxetine Paroxetine 💬
| Paroxetine | 006 [4] 6 , 13, 46, 85 💬
|
956 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
ELANE [1] ELANE 💬
|
Sivelestat Sivelestat 💬
| Sivelestat | 013 [3] 13, 85, 96 💬
|
957 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
958 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
IL10 [2] IL10, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
959 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
960 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
961 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
962 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
963 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
FYN [2] FYN, LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
964 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
FYN [2] FYN, LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
965 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
IL10 [2] IL10, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
966 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
PDCD1 [1] PDCD1 💬
|
Nivolumab Nivolumab 💬
| Nivolumab | 013 [12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
|
967 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
968 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
969 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
970 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
971 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
972 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
973 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
P2RX3 [1] P2RX3 💬
|
Gefapixant Gefapixant 💬
| Gefapixant | 085 [2] 85, 226 💬
|
974 | Taurine and hypotaurine metabolism 💬 2 genes, 1 drug (DrugBank) and 14 diseases |
GAD1 [2] GAD1, GAD2 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
975 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
976 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
977 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
978 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
979 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
980 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
981 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
982 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
IL13 [1] IL13 💬
|
Lebrikizumab Lebrikizumab 💬
| Lebrikizumab | 085 [1] 85 💬
|
983 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
IL13 [1] IL13 💬
|
Tralokinumab Tralokinumab 💬
| Tralokinumab | 085 [2] 85, 97 💬
|
984 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
LCK [1] LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
985 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
LCK [1] LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
986 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
987 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
988 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
989 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL1B [2] IL1B, IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
990 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL6 [1] IL6 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
991 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
LCK [1] LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
992 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
LCK [1] LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
993 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
994 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
995 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
996 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
TGFB1 [1] TGFB1 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
997 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases |
FGFR1 [1] FGFR1 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
998 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
999 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
1000 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
1001 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
1002 | Tight junction 💬 11 genes, 29 drugs (DrugBank) and 45 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
1003 | Tight junction 💬 11 genes, 29 drugs (DrugBank) and 45 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
1004 | Tight junction 💬 11 genes, 29 drugs (DrugBank) and 45 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
1005 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
1006 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
1007 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
LTA [2] LTA, TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
1008 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
1009 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
1010 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
IL1B [3] IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
1011 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
1012 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
1013 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
1014 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
1015 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
ALOX5 [1] ALOX5 💬
|
Zileuton Zileuton 💬
| Zileuton | 085 [3] 85, 160, 164 💬
|
1016 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
1017 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
IL10 [2] IL10, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
1018 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
1019 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
1020 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
1021 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
1022 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
1023 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
ELANE [1] ELANE 💬
|
Sivelestat Sivelestat 💬
| Sivelestat | 013 [3] 13, 85, 96 💬
|
1024 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
FLT1 [1] FLT1 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
1025 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
IL6 [1] IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
1026 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
IL6 [1] IL6 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
1027 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
1028 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
IL10 [5] IL10, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
1029 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
1030 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
1031 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
1032 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
1033 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
1034 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
1035 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
1036 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
1037 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
1038 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
VDR [1] VDR 💬
|
Cholecalciferol Cholecalciferol 💬
| Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
|
1039 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
VDR [1] VDR 💬
|
Dihydrotachysterol Dihydrotachysterol 💬
| Dihydrotachysterol | 006 [2] 6 , 85 💬
|
1040 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
GAD1 [2] GAD1, GAD2 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
1041 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
IL1A [3] IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
1042 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
LTA [2] LTA, TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
1043 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
1044 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
1045 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
1046 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
CACNA1G [1] CACNA1G 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
1047 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
1048 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
1049 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
1050 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
1051 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
1052 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
1053 | Ubiquinone and other terpenoid-quinone biosynthesis 💬 3 genes, 3 drugs (DrugBank) and 14 diseases |
NQO1 [2] NQO1, VKORC1 💬
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Warfarin Warfarin 💬
| Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
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1054 | Valine, leucine and isoleucine degradation 💬 1 gene, 2 drugs (DrugBank) and 16 diseases |
ABAT [1] ABAT 💬
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Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
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1055 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
AGTR1 [1] AGTR1 💬
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Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
1056 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
EDNRA [1] EDNRA 💬
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Ambrisentan Ambrisentan 💬
| Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬
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1057 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
EDNRA [1] EDNRA 💬
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Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
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1058 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
EDNRA [1] EDNRA 💬
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Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
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1059 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
EDNRA [1] EDNRA 💬
|
Macitentan Macitentan 💬
| Macitentan | 051 [5] 51, 85, 86, 88, 210 💬
|
1060 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
PTGIR [1] PTGIR 💬
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Iloprost Iloprost 💬
| Iloprost | 051 [4] 51, 84, 85, 86 💬
|
1061 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
PTGIR [1] PTGIR 💬
|
Treprostinil Treprostinil 💬
| Treprostinil | 051 [6] 51, 84, 85, 86, 88, 210 💬
|
1062 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
1063 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
KDR [1] KDR 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
1064 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
1065 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
1066 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
SRC [1] SRC 💬
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Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
1067 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
1068 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
1069 | Viral carcinogenesis 💬 25 genes, 23 drugs (DrugBank) and 40 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
1070 | Viral carcinogenesis 💬 25 genes, 23 drugs (DrugBank) and 40 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
1071 | Viral myocarditis 💬 10 genes, 19 drugs (DrugBank) and 46 diseases |
ABL1 [1] ABL1 💬
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Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
1072 | Viral myocarditis 💬 10 genes, 19 drugs (DrugBank) and 46 diseases |
ABL1 [2] ABL1, FYN 💬
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Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
1073 | Viral myocarditis 💬 10 genes, 19 drugs (DrugBank) and 46 diseases |
ABL1 [2] ABL1, FYN 💬
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Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
1074 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
CCL2 [4] CCL2, IL10, IL6, TNF 💬
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Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
1075 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
1076 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
LTA [2] LTA, TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
1077 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
1078 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
1079 | Wnt signaling pathway 💬 9 genes, 9 drugs (DrugBank) and 61 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
1080 | Wnt signaling pathway 💬 9 genes, 9 drugs (DrugBank) and 61 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
1081 | Wnt signaling pathway 💬 9 genes, 9 drugs (DrugBank) and 61 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
1082 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
CCL2 [5] CCL2, IL10, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
1083 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
1084 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
LCK [2] LCK, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
1085 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
LCK [2] LCK, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
1086 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
1087 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
1088 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
1089 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|