Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬Acute myeloid leukemia
|
Sirolimus Sirolimus 💬Acute myeloid leukemia
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬1. Acute myeloid leukemia
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
2 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
MTOR [1] MTOR 💬Adipocytokine signaling pathway
|
Sirolimus Sirolimus 💬Adipocytokine signaling pathway
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬2. Adipocytokine signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
3 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬Adipocytokine signaling pathway
|
Infliximab Infliximab 💬Adipocytokine signaling pathway
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬3. Adipocytokine signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
4 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
AGTR1 [1] AGTR1 💬Adrenergic signaling in cardiomyocytes
|
Losartan Losartan 💬Adrenergic signaling in cardiomyocytes
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬4. Adrenergic signaling in cardiomyocytes
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
5 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬African trypanosomiasis
|
Infliximab Infliximab 💬African trypanosomiasis
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬5. African trypanosomiasis
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
6 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
AGTR1 [1] AGTR1 💬AGE-RAGE signaling pathway in diabetic complications
|
Losartan Losartan 💬AGE-RAGE signaling pathway in diabetic complications
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬6. AGE-RAGE signaling pathway in diabetic complications
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
7 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬AGE-RAGE signaling pathway in diabetic complications
|
Infliximab Infliximab 💬AGE-RAGE signaling pathway in diabetic complications
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬7. AGE-RAGE signaling pathway in diabetic complications
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
8 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬Alcoholic liver disease
|
Infliximab Infliximab 💬Alcoholic liver disease
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬8. Alcoholic liver disease
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
9 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
AGTR1 [1] AGTR1 💬Aldosterone synthesis and secretion
|
Losartan Losartan 💬Aldosterone synthesis and secretion
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬9. Aldosterone synthesis and secretion
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
10 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
IL5 [1] IL5 💬Allograft rejection
|
Mepolizumab Mepolizumab 💬Allograft rejection
| Mepolizumab | 044 [4] 44, 45, 98, 162 💬10. Allograft rejection
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
11 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
IL5 [1] IL5 💬Allograft rejection
|
Reslizumab Reslizumab 💬Allograft rejection
| Reslizumab | 044 [2] 44, 98 💬
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
12 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
TNF [1] TNF 💬Allograft rejection
|
Infliximab Infliximab 💬Allograft rejection
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬12. Allograft rejection
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
13 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
MTOR [1] MTOR 💬Alzheimer disease
|
Sirolimus Sirolimus 💬Alzheimer disease
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬13. Alzheimer disease
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
14 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TNF [1] TNF 💬Alzheimer disease
|
Infliximab Infliximab 💬Alzheimer disease
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬14. Alzheimer disease
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
15 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
TNF [1] TNF 💬Amoebiasis
|
Infliximab Infliximab 💬Amoebiasis
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬15. Amoebiasis
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
16 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
MTOR [1] MTOR 💬AMPK signaling pathway
|
Sirolimus Sirolimus 💬AMPK signaling pathway
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬16. AMPK signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
17 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
MTOR [1] MTOR 💬Amyotrophic lateral sclerosis
|
Sirolimus Sirolimus 💬Amyotrophic lateral sclerosis
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬17. Amyotrophic lateral sclerosis
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
18 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF [1] TNF 💬Amyotrophic lateral sclerosis
|
Infliximab Infliximab 💬Amyotrophic lateral sclerosis
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬18. Amyotrophic lateral sclerosis
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
19 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬Antifolate resistance
|
Infliximab Infliximab 💬Antifolate resistance
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬19. Antifolate resistance
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
20 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF [1] TNF 💬Antigen processing and presentation
|
Infliximab Infliximab 💬Antigen processing and presentation
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬20. Antigen processing and presentation
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
21 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
AGTR1 [1] AGTR1 💬Apelin signaling pathway
|
Losartan Losartan 💬Apelin signaling pathway
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬21. Apelin signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
22 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
MTOR [1] MTOR 💬Apelin signaling pathway
|
Sirolimus Sirolimus 💬Apelin signaling pathway
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬22. Apelin signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
23 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬Apoptosis
|
Infliximab Infliximab 💬Apoptosis
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬23. Apoptosis
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
24 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
FCER1A [1] FCER1A 💬Asthma
|
Omalizumab Omalizumab 💬Asthma
| Omalizumab | 046 [7] 46, 53, 65, 98, 162, 226, 299 💬24. Asthma
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
25 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
IL5 [1] IL5 💬Asthma
|
Mepolizumab Mepolizumab 💬Asthma
| Mepolizumab | 044 [4] 44, 45, 98, 162 💬25. Asthma
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
26 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
IL5 [1] IL5 💬Asthma
|
Reslizumab Reslizumab 💬Asthma
| Reslizumab | 044 [2] 44, 98 💬
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
27 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬Asthma
|
Infliximab Infliximab 💬Asthma
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬27. Asthma
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
28 | Autoimmune thyroid disease 💬 22 genes, 15 drugs (DrugBank) and 35 diseases |
IL5 [1] IL5 💬Autoimmune thyroid disease
|
Mepolizumab Mepolizumab 💬Autoimmune thyroid disease
| Mepolizumab | 044 [4] 44, 45, 98, 162 💬28. Autoimmune thyroid disease
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
29 | Autoimmune thyroid disease 💬 22 genes, 15 drugs (DrugBank) and 35 diseases |
IL5 [1] IL5 💬Autoimmune thyroid disease
|
Reslizumab Reslizumab 💬Autoimmune thyroid disease
| Reslizumab | 044 [2] 44, 98 💬29. Autoimmune thyroid disease |
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
30 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬Autophagy - animal
|
Sirolimus Sirolimus 💬Autophagy - animal
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬30. Autophagy - animal
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
31 | Autophagy - other 💬 1 gene, 3 drugs (DrugBank) and 41 diseases |
MTOR [1] MTOR 💬Autophagy - other
|
Sirolimus Sirolimus 💬Autophagy - other
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬31. Autophagy - other
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
32 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
MTOR [1] MTOR 💬Breast cancer
|
Sirolimus Sirolimus 💬Breast cancer
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬32. Breast cancer
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
33 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF [1] TNF 💬C-type lectin receptor signaling pathway
|
Infliximab Infliximab 💬C-type lectin receptor signaling pathway
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬33. C-type lectin receptor signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
34 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
AGTR1 [1] AGTR1 💬Calcium signaling pathway
|
Losartan Losartan 💬Calcium signaling pathway
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬34. Calcium signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
35 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CYSLTR1 [1] CYSLTR1 💬Calcium signaling pathway
|
Montelukast Montelukast 💬Calcium signaling pathway
| Montelukast | 006 [8] 6 , 13, 46, 61, 63, 85, 98, 228 💬35. Calcium signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
36 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HRH1 [1] HRH1 💬Calcium signaling pathway
|
Loratadine Loratadine 💬Calcium signaling pathway
| Loratadine | 013 [4] 13, 46, 89, 98 💬36. Calcium signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
37 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HRH2 [1] HRH2 💬Calcium signaling pathway
|
Famotidine Famotidine 💬Calcium signaling pathway
| Famotidine | 006 [6] 6 , 46, 61, 86, 98, 107 💬37. Calcium signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
38 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MTOR [1] MTOR 💬Cellular senescence
|
Sirolimus Sirolimus 💬Cellular senescence
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬38. Cellular senescence
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
39 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MTOR [1] MTOR 💬Central carbon metabolism in cancer
|
Sirolimus Sirolimus 💬Central carbon metabolism in cancer
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬39. Central carbon metabolism in cancer
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
40 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
AGTR1 [1] AGTR1 💬cGMP-PKG signaling pathway
|
Losartan Losartan 💬cGMP-PKG signaling pathway
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬40. cGMP-PKG signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
41 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬Chagas disease
|
Infliximab Infliximab 💬Chagas disease
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬41. Chagas disease
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
42 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MTOR [1] MTOR 💬Chemical carcinogenesis - receptor activation
|
Sirolimus Sirolimus 💬Chemical carcinogenesis - receptor activation
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬42. Chemical carcinogenesis - receptor activation
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
43 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
VDR [1] VDR 💬Chemical carcinogenesis - receptor activation
|
Cholecalciferol Cholecalciferol 💬Chemical carcinogenesis - receptor activation
| Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬43. Chemical carcinogenesis - receptor activation
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
44 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MTOR [1] MTOR 💬Choline metabolism in cancer
|
Sirolimus Sirolimus 💬Choline metabolism in cancer
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬44. Choline metabolism in cancer
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
45 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 35 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Dexlansoprazole Dexlansoprazole 💬Collecting duct acid secretion
| Dexlansoprazole | 098 [1] 98 💬45. Collecting duct acid secretion
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
46 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 35 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Esomeprazole Esomeprazole 💬Collecting duct acid secretion
| Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬46. Collecting duct acid secretion
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
47 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 35 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Lansoprazole Lansoprazole 💬Collecting duct acid secretion
| Lansoprazole | 063 [7] 63, 71, 85, 98, 166, 222, 299 💬47. Collecting duct acid secretion
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
48 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 35 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Vonoprazan Vonoprazan 💬Collecting duct acid secretion
| Vonoprazan | 063 [2] 63, 98 💬
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
49 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MTOR [1] MTOR 💬Colorectal cancer
|
Sirolimus Sirolimus 💬Colorectal cancer
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬49. Colorectal cancer
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
50 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
AGTR1 [1] AGTR1 💬Coronavirus disease - COVID-19
|
Losartan Losartan 💬Coronavirus disease - COVID-19
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬50. Coronavirus disease - COVID-19
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
51 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬Coronavirus disease - COVID-19
|
Infliximab Infliximab 💬Coronavirus disease - COVID-19
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬51. Coronavirus disease - COVID-19
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
52 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
AGTR1 [1] AGTR1 💬Cortisol synthesis and secretion
|
Losartan Losartan 💬Cortisol synthesis and secretion
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬52. Cortisol synthesis and secretion
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
53 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
AGTR1 [1] AGTR1 💬Cushing syndrome
|
Losartan Losartan 💬Cushing syndrome
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬53. Cushing syndrome
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
54 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL4R [1] IL4R 💬Cytokine-cytokine receptor interaction
|
Dupilumab Dupilumab 💬Cytokine-cytokine receptor interaction
| Dupilumab | 051 [5] 51, 97, 98, 160, 162 💬54. Cytokine-cytokine receptor interaction |
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
55 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL5 [1] IL5 💬Cytokine-cytokine receptor interaction
|
Mepolizumab Mepolizumab 💬Cytokine-cytokine receptor interaction
| Mepolizumab | 044 [4] 44, 45, 98, 162 💬55. Cytokine-cytokine receptor interaction
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
56 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL5 [1] IL5 💬Cytokine-cytokine receptor interaction
|
Reslizumab Reslizumab 💬Cytokine-cytokine receptor interaction
| Reslizumab | 044 [2] 44, 98 💬56. Cytokine-cytokine receptor interaction |
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
57 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL5RA [1] IL5RA 💬Cytokine-cytokine receptor interaction
|
Benralizumab Benralizumab 💬Cytokine-cytokine receptor interaction
| Benralizumab | 044 [5] 44, 45, 98, 162, 299 💬57. Cytokine-cytokine receptor interaction
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
58 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬Cytokine-cytokine receptor interaction
|
Infliximab Infliximab 💬Cytokine-cytokine receptor interaction
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬58. Cytokine-cytokine receptor interaction
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
59 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TSLP [1] TSLP 💬Cytokine-cytokine receptor interaction
|
Tezepelumab Tezepelumab 💬Cytokine-cytokine receptor interaction
| Tezepelumab | 098 [1] 98 💬59. Cytokine-cytokine receptor interaction
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
60 | Diabetic cardiomyopathy 💬 26 genes, 42 drugs (DrugBank) and 73 diseases |
AGTR1 [1] AGTR1 💬Diabetic cardiomyopathy
|
Losartan Losartan 💬Diabetic cardiomyopathy
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬60. Diabetic cardiomyopathy
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
61 | Diabetic cardiomyopathy 💬 26 genes, 42 drugs (DrugBank) and 73 diseases |
MTOR [1] MTOR 💬Diabetic cardiomyopathy
|
Sirolimus Sirolimus 💬Diabetic cardiomyopathy
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬61. Diabetic cardiomyopathy
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
62 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬Dilated cardiomyopathy
|
Infliximab Infliximab 💬Dilated cardiomyopathy
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬62. Dilated cardiomyopathy
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
63 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
MTOR [1] MTOR 💬EGFR tyrosine kinase inhibitor resistance
|
Sirolimus Sirolimus 💬EGFR tyrosine kinase inhibitor resistance
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬63. EGFR tyrosine kinase inhibitor resistance
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
64 | Endocrine and other factor-regulated calcium reabsorption 💬 8 genes, 27 drugs (DrugBank) and 55 diseases |
VDR [1] VDR 💬Endocrine and other factor-regulated calcium reabsorption
|
Cholecalciferol Cholecalciferol 💬Endocrine and other factor-regulated calcium reabsorption
| Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬64. Endocrine and other factor-regulated calcium reabsorption
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
65 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬Endocrine resistance
|
Sirolimus Sirolimus 💬Endocrine resistance
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬65. Endocrine resistance
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
66 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬Epstein-Barr virus infection
|
Infliximab Infliximab 💬Epstein-Barr virus infection
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬66. Epstein-Barr virus infection
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
67 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MTOR [1] MTOR 💬ErbB signaling pathway
|
Sirolimus Sirolimus 💬ErbB signaling pathway
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬67. ErbB signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
68 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
FCER1A [1] FCER1A 💬Fc epsilon RI signaling pathway
|
Omalizumab Omalizumab 💬Fc epsilon RI signaling pathway
| Omalizumab | 046 [7] 46, 53, 65, 98, 162, 226, 299 💬68. Fc epsilon RI signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
69 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
IL5 [1] IL5 💬Fc epsilon RI signaling pathway
|
Mepolizumab Mepolizumab 💬Fc epsilon RI signaling pathway
| Mepolizumab | 044 [4] 44, 45, 98, 162 💬69. Fc epsilon RI signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
70 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
IL5 [1] IL5 💬Fc epsilon RI signaling pathway
|
Reslizumab Reslizumab 💬Fc epsilon RI signaling pathway
| Reslizumab | 044 [2] 44, 98 💬70. Fc epsilon RI signaling pathway |
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
71 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬Fc epsilon RI signaling pathway
|
Infliximab Infliximab 💬Fc epsilon RI signaling pathway
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬71. Fc epsilon RI signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
72 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬Fluid shear stress and atherosclerosis
|
Infliximab Infliximab 💬Fluid shear stress and atherosclerosis
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬72. Fluid shear stress and atherosclerosis
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
73 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
S1PR1 [2] S1PR1, S1PR4 💬
|
Etrasimod Etrasimod 💬FoxO signaling pathway
| Etrasimod | 096 [3] 96, 97, 98 💬
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
74 | GABAergic synapse 💬 29 genes, 38 drugs (DrugBank) and 55 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬GABAergic synapse
|
Propofol Propofol 💬GABAergic synapse
| Propofol | 006 [9] 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬74. GABAergic synapse
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
75 | Gastric acid secretion 💬 14 genes, 43 drugs (DrugBank) and 52 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Dexlansoprazole Dexlansoprazole 💬Gastric acid secretion
| Dexlansoprazole | 098 [1] 98 💬75. Gastric acid secretion
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
76 | Gastric acid secretion 💬 14 genes, 43 drugs (DrugBank) and 52 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Esomeprazole Esomeprazole 💬Gastric acid secretion
| Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬76. Gastric acid secretion
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
77 | Gastric acid secretion 💬 14 genes, 43 drugs (DrugBank) and 52 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Lansoprazole Lansoprazole 💬Gastric acid secretion
| Lansoprazole | 063 [7] 63, 71, 85, 98, 166, 222, 299 💬77. Gastric acid secretion
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
78 | Gastric acid secretion 💬 14 genes, 43 drugs (DrugBank) and 52 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Vonoprazan Vonoprazan 💬Gastric acid secretion
| Vonoprazan | 063 [2] 63, 98 💬
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
79 | Gastric acid secretion 💬 14 genes, 43 drugs (DrugBank) and 52 diseases |
HRH2 [1] HRH2 💬Gastric acid secretion
|
Famotidine Famotidine 💬Gastric acid secretion
| Famotidine | 006 [6] 6 , 46, 61, 86, 98, 107 💬79. Gastric acid secretion
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
80 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬Gastric cancer
|
Sirolimus Sirolimus 💬Gastric cancer
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬80. Gastric cancer
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
81 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬Glioma
|
Sirolimus Sirolimus 💬Glioma
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬81. Glioma
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
82 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬Graft-versus-host disease
|
Infliximab Infliximab 💬Graft-versus-host disease
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬82. Graft-versus-host disease
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
83 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
MTOR [1] MTOR 💬Growth hormone synthesis, secretion and action
|
Sirolimus Sirolimus 💬Growth hormone synthesis, secretion and action
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬83. Growth hormone synthesis, secretion and action
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
84 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL4R [1] IL4R 💬Hematopoietic cell lineage
|
Dupilumab Dupilumab 💬Hematopoietic cell lineage
| Dupilumab | 051 [5] 51, 97, 98, 160, 162 💬84. Hematopoietic cell lineage |
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
85 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL5 [1] IL5 💬Hematopoietic cell lineage
|
Mepolizumab Mepolizumab 💬Hematopoietic cell lineage
| Mepolizumab | 044 [4] 44, 45, 98, 162 💬85. Hematopoietic cell lineage
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
86 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL5 [1] IL5 💬Hematopoietic cell lineage
|
Reslizumab Reslizumab 💬Hematopoietic cell lineage
| Reslizumab | 044 [2] 44, 98 💬86. Hematopoietic cell lineage |
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
87 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL5RA [1] IL5RA 💬Hematopoietic cell lineage
|
Benralizumab Benralizumab 💬Hematopoietic cell lineage
| Benralizumab | 044 [5] 44, 45, 98, 162, 299 💬87. Hematopoietic cell lineage
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
88 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
TNF [1] TNF 💬Hematopoietic cell lineage
|
Infliximab Infliximab 💬Hematopoietic cell lineage
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬88. Hematopoietic cell lineage
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
89 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬Hepatitis B
|
Infliximab Infliximab 💬Hepatitis B
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬89. Hepatitis B
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
90 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF [1] TNF 💬Hepatitis C
|
Infliximab Infliximab 💬Hepatitis C
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬90. Hepatitis C
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
91 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬Hepatocellular carcinoma
|
Sirolimus Sirolimus 💬Hepatocellular carcinoma
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬91. Hepatocellular carcinoma
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
92 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
MTOR [1] MTOR 💬Herpes simplex virus 1 infection
|
Sirolimus Sirolimus 💬Herpes simplex virus 1 infection
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬92. Herpes simplex virus 1 infection
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
93 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
TNF [1] TNF 💬Herpes simplex virus 1 infection
|
Infliximab Infliximab 💬Herpes simplex virus 1 infection
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬93. Herpes simplex virus 1 infection
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
94 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
MTOR [1] MTOR 💬HIF-1 signaling pathway
|
Sirolimus Sirolimus 💬HIF-1 signaling pathway
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬94. HIF-1 signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
95 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
MTOR [1] MTOR 💬Human cytomegalovirus infection
|
Sirolimus Sirolimus 💬Human cytomegalovirus infection
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬95. Human cytomegalovirus infection
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
96 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
TNF [1] TNF 💬Human cytomegalovirus infection
|
Infliximab Infliximab 💬Human cytomegalovirus infection
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬96. Human cytomegalovirus infection
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
97 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
MTOR [1] MTOR 💬Human immunodeficiency virus 1 infection
|
Sirolimus Sirolimus 💬Human immunodeficiency virus 1 infection
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬97. Human immunodeficiency virus 1 infection
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
98 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬Human immunodeficiency virus 1 infection
|
Infliximab Infliximab 💬Human immunodeficiency virus 1 infection
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬98. Human immunodeficiency virus 1 infection
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
99 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
MTOR [1] MTOR 💬Human papillomavirus infection
|
Sirolimus Sirolimus 💬Human papillomavirus infection
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬99. Human papillomavirus infection
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
100 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF [1] TNF 💬Human papillomavirus infection
|
Infliximab Infliximab 💬Human papillomavirus infection
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬100. Human papillomavirus infection
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
101 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬Human T-cell leukemia virus 1 infection
|
Infliximab Infliximab 💬Human T-cell leukemia virus 1 infection
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬101. Human T-cell leukemia virus 1 infection
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
102 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
MTOR [1] MTOR 💬Huntington disease
|
Sirolimus Sirolimus 💬Huntington disease
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬102. Huntington disease
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
103 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬Hypertrophic cardiomyopathy
|
Infliximab Infliximab 💬Hypertrophic cardiomyopathy
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬103. Hypertrophic cardiomyopathy
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
104 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL5 [1] IL5 💬IL-17 signaling pathway
|
Mepolizumab Mepolizumab 💬IL-17 signaling pathway
| Mepolizumab | 044 [4] 44, 45, 98, 162 💬104. IL-17 signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
105 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL5 [1] IL5 💬IL-17 signaling pathway
|
Reslizumab Reslizumab 💬IL-17 signaling pathway
| Reslizumab | 044 [2] 44, 98 💬105. IL-17 signaling pathway |
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
106 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬IL-17 signaling pathway
|
Infliximab Infliximab 💬IL-17 signaling pathway
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬106. IL-17 signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
107 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL4R [1] IL4R 💬Inflammatory bowel disease
|
Dupilumab Dupilumab 💬Inflammatory bowel disease
| Dupilumab | 051 [5] 51, 97, 98, 160, 162 💬107. Inflammatory bowel disease |
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
108 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL5 [1] IL5 💬Inflammatory bowel disease
|
Mepolizumab Mepolizumab 💬Inflammatory bowel disease
| Mepolizumab | 044 [4] 44, 45, 98, 162 💬108. Inflammatory bowel disease
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
109 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL5 [1] IL5 💬Inflammatory bowel disease
|
Reslizumab Reslizumab 💬Inflammatory bowel disease
| Reslizumab | 044 [2] 44, 98 💬109. Inflammatory bowel disease |
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
110 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬Inflammatory bowel disease
|
Infliximab Infliximab 💬Inflammatory bowel disease
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬110. Inflammatory bowel disease
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
111 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
HRH1 [1] HRH1 💬Inflammatory mediator regulation of TRP channels
|
Loratadine Loratadine 💬Inflammatory mediator regulation of TRP channels
| Loratadine | 013 [4] 13, 46, 89, 98 💬111. Inflammatory mediator regulation of TRP channels
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
112 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
TNF [1] TNF 💬Influenza A
|
Infliximab Infliximab 💬Influenza A
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬112. Influenza A
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
113 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
MTOR [1] MTOR 💬Insulin resistance
|
Sirolimus Sirolimus 💬Insulin resistance
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬113. Insulin resistance
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
114 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬Insulin resistance
|
Infliximab Infliximab 💬Insulin resistance
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬114. Insulin resistance
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
115 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
MTOR [1] MTOR 💬Insulin signaling pathway
|
Sirolimus Sirolimus 💬Insulin signaling pathway
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬115. Insulin signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
116 | Intestinal immune network for IgA production 💬 16 genes, 27 drugs (DrugBank) and 47 diseases |
IL5 [1] IL5 💬Intestinal immune network for IgA production
|
Mepolizumab Mepolizumab 💬Intestinal immune network for IgA production
| Mepolizumab | 044 [4] 44, 45, 98, 162 💬116. Intestinal immune network for IgA production
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
117 | Intestinal immune network for IgA production 💬 16 genes, 27 drugs (DrugBank) and 47 diseases |
IL5 [1] IL5 💬Intestinal immune network for IgA production
|
Reslizumab Reslizumab 💬Intestinal immune network for IgA production
| Reslizumab | 044 [2] 44, 98 💬117. Intestinal immune network for IgA production |
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
118 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL4R [1] IL4R 💬JAK-STAT signaling pathway
|
Dupilumab Dupilumab 💬JAK-STAT signaling pathway
| Dupilumab | 051 [5] 51, 97, 98, 160, 162 💬118. JAK-STAT signaling pathway |
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
119 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL5 [1] IL5 💬JAK-STAT signaling pathway
|
Mepolizumab Mepolizumab 💬JAK-STAT signaling pathway
| Mepolizumab | 044 [4] 44, 45, 98, 162 💬119. JAK-STAT signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
120 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL5 [1] IL5 💬JAK-STAT signaling pathway
|
Reslizumab Reslizumab 💬JAK-STAT signaling pathway
| Reslizumab | 044 [2] 44, 98 💬120. JAK-STAT signaling pathway |
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
121 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL5RA [1] IL5RA 💬JAK-STAT signaling pathway
|
Benralizumab Benralizumab 💬JAK-STAT signaling pathway
| Benralizumab | 044 [5] 44, 45, 98, 162, 299 💬121. JAK-STAT signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
122 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
MTOR [1] MTOR 💬JAK-STAT signaling pathway
|
Sirolimus Sirolimus 💬JAK-STAT signaling pathway
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬122. JAK-STAT signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
123 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
TSLP [1] TSLP 💬JAK-STAT signaling pathway
|
Tezepelumab Tezepelumab 💬JAK-STAT signaling pathway
| Tezepelumab | 098 [1] 98 💬123. JAK-STAT signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
124 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
MTOR [1] MTOR 💬Kaposi sarcoma-associated herpesvirus infection
|
Sirolimus Sirolimus 💬Kaposi sarcoma-associated herpesvirus infection
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬124. Kaposi sarcoma-associated herpesvirus infection
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
125 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬Legionellosis
|
Infliximab Infliximab 💬Legionellosis
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬125. Legionellosis
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
126 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬Leishmaniasis
|
Infliximab Infliximab 💬Leishmaniasis
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬126. Leishmaniasis
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
127 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬Lipid and atherosclerosis
|
Infliximab Infliximab 💬Lipid and atherosclerosis
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬127. Lipid and atherosclerosis
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
128 | Longevity regulating pathway 💬 11 genes, 20 drugs (DrugBank) and 68 diseases |
MTOR [1] MTOR 💬Longevity regulating pathway
|
Sirolimus Sirolimus 💬Longevity regulating pathway
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬128. Longevity regulating pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
129 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬Longevity regulating pathway - multiple species
|
Sirolimus Sirolimus 💬Longevity regulating pathway - multiple species
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬129. Longevity regulating pathway - multiple species
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
130 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬Malaria
|
Infliximab Infliximab 💬Malaria
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬130. Malaria
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
131 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF [1] TNF 💬MAPK signaling pathway
|
Infliximab Infliximab 💬MAPK signaling pathway
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬131. MAPK signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
132 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Dexlansoprazole Dexlansoprazole 💬Metabolic pathways
| Dexlansoprazole | 098 [1] 98 💬132. Metabolic pathways
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
133 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Esomeprazole Esomeprazole 💬Metabolic pathways
| Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬133. Metabolic pathways
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
134 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Lansoprazole Lansoprazole 💬Metabolic pathways
| Lansoprazole | 063 [7] 63, 71, 85, 98, 166, 222, 299 💬134. Metabolic pathways
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
135 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Vonoprazan Vonoprazan 💬Metabolic pathways
| Vonoprazan | 063 [2] 63, 98 💬
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
136 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MTOR [1] MTOR 💬MicroRNAs in cancer
|
Sirolimus Sirolimus 💬MicroRNAs in cancer
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬136. MicroRNAs in cancer
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
137 | Mineral absorption 💬 8 genes, 13 drugs (DrugBank) and 41 diseases |
VDR [1] VDR 💬Mineral absorption
|
Cholecalciferol Cholecalciferol 💬Mineral absorption
| Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬137. Mineral absorption
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
138 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬Morphine addiction
|
Propofol Propofol 💬Morphine addiction
| Propofol | 006 [9] 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬138. Morphine addiction
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
139 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
MTOR [1] MTOR 💬mTOR signaling pathway
|
Sirolimus Sirolimus 💬mTOR signaling pathway
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬139. mTOR signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
140 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬mTOR signaling pathway
|
Infliximab Infliximab 💬mTOR signaling pathway
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬140. mTOR signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
141 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬Natural killer cell mediated cytotoxicity
|
Infliximab Infliximab 💬Natural killer cell mediated cytotoxicity
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬141. Natural killer cell mediated cytotoxicity
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
142 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬Necroptosis
|
Infliximab Infliximab 💬Necroptosis
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬142. Necroptosis
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
143 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
AGTR1 [1] AGTR1 💬Neuroactive ligand-receptor interaction
|
Losartan Losartan 💬Neuroactive ligand-receptor interaction
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬143. Neuroactive ligand-receptor interaction
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
144 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CYSLTR1 [1] CYSLTR1 💬Neuroactive ligand-receptor interaction
|
Montelukast Montelukast 💬Neuroactive ligand-receptor interaction
| Montelukast | 006 [8] 6 , 13, 46, 61, 63, 85, 98, 228 💬144. Neuroactive ligand-receptor interaction
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
145 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬Neuroactive ligand-receptor interaction
|
Propofol Propofol 💬Neuroactive ligand-receptor interaction
| Propofol | 006 [9] 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬145. Neuroactive ligand-receptor interaction
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
146 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HRH1 [1] HRH1 💬Neuroactive ligand-receptor interaction
|
Loratadine Loratadine 💬Neuroactive ligand-receptor interaction
| Loratadine | 013 [4] 13, 46, 89, 98 💬146. Neuroactive ligand-receptor interaction
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
147 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HRH2 [1] HRH2 💬Neuroactive ligand-receptor interaction
|
Famotidine Famotidine 💬Neuroactive ligand-receptor interaction
| Famotidine | 006 [6] 6 , 46, 61, 86, 98, 107 💬147. Neuroactive ligand-receptor interaction
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
148 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬Neuroactive ligand-receptor interaction
|
Beclomethasone dipropionate Beclomethasone dipropionate 💬Neuroactive ligand-receptor interaction
| Beclomethasone dipropionate | 085 [3] 85, 97, 98 💬
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
149 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬Neuroactive ligand-receptor interaction
|
Budesonide Budesonide 💬Neuroactive ligand-receptor interaction
| Budesonide | 066 [9] 66, 93, 94, 95, 96, 97, 98, 228, 299 💬149. Neuroactive ligand-receptor interaction
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
150 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬Neuroactive ligand-receptor interaction
|
Fluticasone Fluticasone 💬Neuroactive ligand-receptor interaction
| Fluticasone | 098 [3] 98, 228, 299 💬
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
151 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬Neuroactive ligand-receptor interaction
|
Fluticasone propionate Fluticasone propionate 💬Neuroactive ligand-receptor interaction
| Fluticasone propionate | 098 [2] 98, 228 💬
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
152 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬Neuroactive ligand-receptor interaction
|
Mometasone Mometasone 💬Neuroactive ligand-receptor interaction
| Mometasone | 098 [2] 98, 162 💬
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
153 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬Neuroactive ligand-receptor interaction
|
Mometasone furoate Mometasone furoate 💬Neuroactive ligand-receptor interaction
| Mometasone furoate | 098 [2] 98, 162 💬
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
154 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
S1PR1 [5] S1PR1, S1PR2, S1PR3, S1PR4, S1PR5 💬
|
Etrasimod Etrasimod 💬Neuroactive ligand-receptor interaction
| Etrasimod | 096 [3] 96, 97, 98 💬
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
155 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MTOR [1] MTOR 💬Neutrophil extracellular trap formation
|
Sirolimus Sirolimus 💬Neutrophil extracellular trap formation
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬155. Neutrophil extracellular trap formation
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
156 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬NF-kappa B signaling pathway
|
Infliximab Infliximab 💬NF-kappa B signaling pathway
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬156. NF-kappa B signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
157 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬Nicotine addiction
|
Propofol Propofol 💬Nicotine addiction
| Propofol | 006 [9] 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬157. Nicotine addiction
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
158 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬NOD-like receptor signaling pathway
|
Infliximab Infliximab 💬NOD-like receptor signaling pathway
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬158. NOD-like receptor signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
159 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬Non-alcoholic fatty liver disease
|
Infliximab Infliximab 💬Non-alcoholic fatty liver disease
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬159. Non-alcoholic fatty liver disease
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
160 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬Osteoclast differentiation
|
Infliximab Infliximab 💬Osteoclast differentiation
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬160. Osteoclast differentiation
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
161 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 25 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Dexlansoprazole Dexlansoprazole 💬Oxidative phosphorylation
| Dexlansoprazole | 098 [1] 98 💬161. Oxidative phosphorylation
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
162 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 25 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Esomeprazole Esomeprazole 💬Oxidative phosphorylation
| Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬162. Oxidative phosphorylation
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
163 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 25 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Lansoprazole Lansoprazole 💬Oxidative phosphorylation
| Lansoprazole | 063 [7] 63, 71, 85, 98, 166, 222, 299 💬163. Oxidative phosphorylation
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
164 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 25 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Vonoprazan Vonoprazan 💬Oxidative phosphorylation
| Vonoprazan | 063 [2] 63, 98 💬
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
165 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
MTOR [1] MTOR 💬Pancreatic cancer
|
Sirolimus Sirolimus 💬Pancreatic cancer
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬165. Pancreatic cancer
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
166 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
VDR [1] VDR 💬Parathyroid hormone synthesis, secretion and action
|
Cholecalciferol Cholecalciferol 💬Parathyroid hormone synthesis, secretion and action
| Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬166. Parathyroid hormone synthesis, secretion and action
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
167 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬Pathogenic Escherichia coli infection
|
Infliximab Infliximab 💬Pathogenic Escherichia coli infection
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬167. Pathogenic Escherichia coli infection
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
168 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AGTR1 [1] AGTR1 💬Pathways in cancer
|
Losartan Losartan 💬Pathways in cancer
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬168. Pathways in cancer
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
169 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL4R [1] IL4R 💬Pathways in cancer
|
Dupilumab Dupilumab 💬Pathways in cancer
| Dupilumab | 051 [5] 51, 97, 98, 160, 162 💬
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
170 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL5 [1] IL5 💬Pathways in cancer
|
Mepolizumab Mepolizumab 💬Pathways in cancer
| Mepolizumab | 044 [4] 44, 45, 98, 162 💬170. Pathways in cancer
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
171 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL5 [1] IL5 💬Pathways in cancer
|
Reslizumab Reslizumab 💬Pathways in cancer
| Reslizumab | 044 [2] 44, 98 💬
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
172 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL5RA [1] IL5RA 💬Pathways in cancer
|
Benralizumab Benralizumab 💬Pathways in cancer
| Benralizumab | 044 [5] 44, 45, 98, 162, 299 💬172. Pathways in cancer
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
173 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MTOR [1] MTOR 💬Pathways in cancer
|
Sirolimus Sirolimus 💬Pathways in cancer
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬173. Pathways in cancer
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
174 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MTOR [1] MTOR 💬Pathways of neurodegeneration - multiple diseases
|
Sirolimus Sirolimus 💬Pathways of neurodegeneration - multiple diseases
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬174. Pathways of neurodegeneration - multiple diseases
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
175 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF [1] TNF 💬Pathways of neurodegeneration - multiple diseases
|
Infliximab Infliximab 💬Pathways of neurodegeneration - multiple diseases
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬175. Pathways of neurodegeneration - multiple diseases
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
176 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MTOR [1] MTOR 💬PD-L1 expression and PD-1 checkpoint pathway in cancer
|
Sirolimus Sirolimus 💬PD-L1 expression and PD-1 checkpoint pathway in cancer
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬176. PD-L1 expression and PD-1 checkpoint pathway in cancer
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
177 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬Pertussis
|
Infliximab Infliximab 💬Pertussis
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬177. Pertussis
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
178 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
AGTR1 [1] AGTR1 💬Phospholipase D signaling pathway
|
Losartan Losartan 💬Phospholipase D signaling pathway
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬178. Phospholipase D signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
179 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
FCER1A [1] FCER1A 💬Phospholipase D signaling pathway
|
Omalizumab Omalizumab 💬Phospholipase D signaling pathway
| Omalizumab | 046 [7] 46, 53, 65, 98, 162, 226, 299 💬179. Phospholipase D signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
180 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
MTOR [1] MTOR 💬Phospholipase D signaling pathway
|
Sirolimus Sirolimus 💬Phospholipase D signaling pathway
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬180. Phospholipase D signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
181 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL4R [1] IL4R 💬PI3K-Akt signaling pathway
|
Dupilumab Dupilumab 💬PI3K-Akt signaling pathway
| Dupilumab | 051 [5] 51, 97, 98, 160, 162 💬181. PI3K-Akt signaling pathway |
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
182 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
MTOR [1] MTOR 💬PI3K-Akt signaling pathway
|
Sirolimus Sirolimus 💬PI3K-Akt signaling pathway
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬182. PI3K-Akt signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
183 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF [1] TNF 💬Prion disease
|
Infliximab Infliximab 💬Prion disease
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬183. Prion disease
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
184 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
MTOR [1] MTOR 💬Prostate cancer
|
Sirolimus Sirolimus 💬Prostate cancer
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬184. Prostate cancer
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
185 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MTOR [1] MTOR 💬Proteoglycans in cancer
|
Sirolimus Sirolimus 💬Proteoglycans in cancer
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬185. Proteoglycans in cancer
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
186 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬Proteoglycans in cancer
|
Infliximab Infliximab 💬Proteoglycans in cancer
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬186. Proteoglycans in cancer
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
187 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
AGTR1 [1] AGTR1 💬Renin secretion
|
Losartan Losartan 💬Renin secretion
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬187. Renin secretion
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
188 | Renin-angiotensin system 💬 6 genes, 21 drugs (DrugBank) and 31 diseases |
AGTR1 [1] AGTR1 💬Renin-angiotensin system
|
Losartan Losartan 💬Renin-angiotensin system
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬188. Renin-angiotensin system
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
189 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬Retrograde endocannabinoid signaling
|
Propofol Propofol 💬Retrograde endocannabinoid signaling
| Propofol | 006 [9] 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬189. Retrograde endocannabinoid signaling
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
190 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬Rheumatoid arthritis
|
Infliximab Infliximab 💬Rheumatoid arthritis
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬190. Rheumatoid arthritis
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
191 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬RIG-I-like receptor signaling pathway
|
Infliximab Infliximab 💬RIG-I-like receptor signaling pathway
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬191. RIG-I-like receptor signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
192 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬Salmonella infection
|
Infliximab Infliximab 💬Salmonella infection
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬192. Salmonella infection
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
193 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
GABRB1 [3] GABRB1, GABRB2, GABRB3 💬
|
Propofol Propofol 💬Serotonergic synapse
| Propofol | 006 [9] 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬193. Serotonergic synapse
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
194 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
SLC6A4 [1] SLC6A4 💬Serotonergic synapse
|
Citalopram Citalopram 💬Serotonergic synapse
| Citalopram | 006 [7] 6 , 8 , 13, 18, 46, 98, 127 💬194. Serotonergic synapse
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
195 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
MTOR [1] MTOR 💬Shigellosis
|
Sirolimus Sirolimus 💬Shigellosis
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬195. Shigellosis
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
196 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬Shigellosis
|
Infliximab Infliximab 💬Shigellosis
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬196. Shigellosis
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
197 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
FCER1A [1] FCER1A 💬Sphingolipid signaling pathway
|
Omalizumab Omalizumab 💬Sphingolipid signaling pathway
| Omalizumab | 046 [7] 46, 53, 65, 98, 162, 226, 299 💬197. Sphingolipid signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
198 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
S1PR1 [5] S1PR1, S1PR2, S1PR3, S1PR4, S1PR5 💬
|
Etrasimod Etrasimod 💬Sphingolipid signaling pathway
| Etrasimod | 096 [3] 96, 97, 98 💬
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
199 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬Sphingolipid signaling pathway
|
Infliximab Infliximab 💬Sphingolipid signaling pathway
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬199. Sphingolipid signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
200 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
MTOR [1] MTOR 💬Spinocerebellar ataxia
|
Sirolimus Sirolimus 💬Spinocerebellar ataxia
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬200. Spinocerebellar ataxia
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
201 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A4 [1] SLC6A4 💬Synaptic vesicle cycle
|
Citalopram Citalopram 💬Synaptic vesicle cycle
| Citalopram | 006 [7] 6 , 8 , 13, 18, 46, 98, 127 💬201. Synaptic vesicle cycle
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
202 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF [1] TNF 💬Systemic lupus erythematosus
|
Infliximab Infliximab 💬Systemic lupus erythematosus
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬202. Systemic lupus erythematosus
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
203 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
IL5 [1] IL5 💬T cell receptor signaling pathway
|
Mepolizumab Mepolizumab 💬T cell receptor signaling pathway
| Mepolizumab | 044 [4] 44, 45, 98, 162 💬203. T cell receptor signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
204 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
IL5 [1] IL5 💬T cell receptor signaling pathway
|
Reslizumab Reslizumab 💬T cell receptor signaling pathway
| Reslizumab | 044 [2] 44, 98 💬204. T cell receptor signaling pathway |
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
205 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬T cell receptor signaling pathway
|
Infliximab Infliximab 💬T cell receptor signaling pathway
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬205. T cell receptor signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
206 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬Taste transduction
|
Propofol Propofol 💬Taste transduction
| Propofol | 006 [9] 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬206. Taste transduction
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
207 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬TGF-beta signaling pathway
|
Infliximab Infliximab 💬TGF-beta signaling pathway
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬207. TGF-beta signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
208 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
IL4R [1] IL4R 💬Th1 and Th2 cell differentiation
|
Dupilumab Dupilumab 💬Th1 and Th2 cell differentiation
| Dupilumab | 051 [5] 51, 97, 98, 160, 162 💬208. Th1 and Th2 cell differentiation |
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
209 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
IL5 [1] IL5 💬Th1 and Th2 cell differentiation
|
Mepolizumab Mepolizumab 💬Th1 and Th2 cell differentiation
| Mepolizumab | 044 [4] 44, 45, 98, 162 💬209. Th1 and Th2 cell differentiation
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
210 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
IL5 [1] IL5 💬Th1 and Th2 cell differentiation
|
Reslizumab Reslizumab 💬Th1 and Th2 cell differentiation
| Reslizumab | 044 [2] 44, 98 💬210. Th1 and Th2 cell differentiation |
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
211 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL4R [1] IL4R 💬Th17 cell differentiation
|
Dupilumab Dupilumab 💬Th17 cell differentiation
| Dupilumab | 051 [5] 51, 97, 98, 160, 162 💬211. Th17 cell differentiation |
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
212 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
MTOR [1] MTOR 💬Th17 cell differentiation
|
Sirolimus Sirolimus 💬Th17 cell differentiation
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬212. Th17 cell differentiation
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
213 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases |
MTOR [1] MTOR 💬Thermogenesis
|
Sirolimus Sirolimus 💬Thermogenesis
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬213. Thermogenesis
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
214 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
MTOR [1] MTOR 💬Thyroid hormone signaling pathway
|
Sirolimus Sirolimus 💬Thyroid hormone signaling pathway
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬214. Thyroid hormone signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
215 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬TNF signaling pathway
|
Infliximab Infliximab 💬TNF signaling pathway
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬215. TNF signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
216 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬Toll-like receptor signaling pathway
|
Infliximab Infliximab 💬Toll-like receptor signaling pathway
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬216. Toll-like receptor signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
217 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬Toxoplasmosis
|
Infliximab Infliximab 💬Toxoplasmosis
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬217. Toxoplasmosis
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
218 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬Tuberculosis
|
Infliximab Infliximab 💬Tuberculosis
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬218. Tuberculosis
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
219 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
VDR [1] VDR 💬Tuberculosis
|
Cholecalciferol Cholecalciferol 💬Tuberculosis
| Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬219. Tuberculosis
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
220 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬Type I diabetes mellitus
|
Infliximab Infliximab 💬Type I diabetes mellitus
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬220. Type I diabetes mellitus
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
221 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
MTOR [1] MTOR 💬Type II diabetes mellitus
|
Sirolimus Sirolimus 💬Type II diabetes mellitus
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬221. Type II diabetes mellitus
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
222 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬Type II diabetes mellitus
|
Infliximab Infliximab 💬Type II diabetes mellitus
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬222. Type II diabetes mellitus
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
223 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
AGTR1 [1] AGTR1 💬Vascular smooth muscle contraction
|
Losartan Losartan 💬Vascular smooth muscle contraction
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬223. Vascular smooth muscle contraction
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
224 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬Viral protein interaction with cytokine and cytokine receptor
|
Infliximab Infliximab 💬Viral protein interaction with cytokine and cytokine receptor
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬224. Viral protein interaction with cytokine and cytokine receptor
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
225 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬Yersinia infection
|
Infliximab Infliximab 💬Yersinia infection
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬225. Yersinia infection
|