Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
BCL2 [1] BCL2 💬
|
Venetoclax Venetoclax 💬
| Venetoclax | 028 [1] 28 💬
|
2 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
CASP9 [1] CASP9 💬
|
Rimiducid Rimiducid 💬
| Rimiducid | 019 [6] 19, 60, 65, 284, 285, 326 💬
|
3 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
4 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
CD40 [1] CD40 💬
|
Bleselumab Bleselumab 💬
| Bleselumab | 222 [1] 222 💬
|
5 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
CD40 [1] CD40 💬
|
Iscalimab Iscalimab 💬
| Iscalimab | 049 [2] 49, 53 💬
|
6 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
CD40 [1] CD40 💬
|
Ravagalimab Ravagalimab 💬
| Ravagalimab | 053 [2] 53, 97 💬
|
7 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
CD40LG [1] CD40LG 💬
|
Toralizumab Toralizumab 💬
| Toralizumab | 063 [1] 63 💬
|
8 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬
|
Rontalizumab Rontalizumab 💬
| Rontalizumab | 049 [1] 49 💬
|
9 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬
|
Sifalimumab Sifalimumab 💬
| Sifalimumab | 049 [1] 49 💬
|
10 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
IL12A [2] IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
11 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
12 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
13 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
IL1B [1] IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 [4] 51, 106, 107, 266 💬
|
14 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
IL6 [1] IL6 💬
|
Olokizumab Olokizumab 💬
| Olokizumab | 046 [2] 46, 96 💬
|
15 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
IL6 [1] IL6 💬
|
Siltuximab Siltuximab 💬
| Siltuximab | 028 [2] 28, 331 💬
|
16 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
IL6 [1] IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 [2] 41, 46 💬
|
17 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
18 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
JAK2 [1] JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
19 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
JAK2 [1] JAK2 💬
|
Peficitinib Peficitinib 💬
| Peficitinib | 046 [1] 46 💬
|
20 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
JAK2 [1] JAK2 💬
|
Ruxolitinib Ruxolitinib 💬
| Ruxolitinib | 060 [3] 60, 65, 228 💬
|
21 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
JAK2 [1] JAK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
22 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
MAP3K5 [1] MAP3K5 💬
|
Selonsertib Selonsertib 💬
| Selonsertib | 086 [1] 86 💬
|
23 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Losmapimod Losmapimod 💬
| Losmapimod | 113 [2] 113, 222 💬
|
24 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
25 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
NFE2L2 [1] NFE2L2 💬
|
Omaveloxolone Omaveloxolone 💬
| Omaveloxolone | 018 [1] 18 💬
|
26 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
NFKB1 [1] NFKB1 💬
|
Iguratimod Iguratimod 💬
| Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬
|
27 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PIK3CA [1] PIK3CA 💬
|
Alpelisib Alpelisib 💬
| Alpelisib | 138 [1] 138 💬
|
28 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬
|
Leniolisib Leniolisib 💬
| Leniolisib | 053 [2] 53, 65 💬
|
29 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PIK3CD [1] PIK3CD 💬
|
Parsaclisib Parsaclisib 💬
| Parsaclisib | 035 [3] 35, 53, 61 💬
|
30 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PPARG [1] PPARG 💬
|
Bocidelpar Bocidelpar 💬
| Bocidelpar | 113 [1] 113 💬
|
31 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PPARG [1] PPARG 💬
|
Leriglitazone Leriglitazone 💬
| Leriglitazone | 020 [1] 20 💬
|
32 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PPARG [1] PPARG 💬
|
Pioglitazone Pioglitazone 💬
| Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
|
33 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PPARG [1] PPARG 💬
|
Rosiglitazone Rosiglitazone 💬
| Rosiglitazone | 046 [5] 46, 75, 97, 222, 265 💬
|
34 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PPARG [1] PPARG 💬
|
Seladelpar Seladelpar 💬
| Seladelpar | 093 [2] 93, 94 💬
|
35 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
36 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Pimecrolimus Pimecrolimus 💬
| Pimecrolimus | 160 [1] 160 💬
|
37 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
38 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
39 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Voclosporin Voclosporin 💬
| Voclosporin | 049 [2] 49, 222 💬
|
40 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
RELA [1] RELA 💬
|
Edasalonexent Edasalonexent 💬
| Edasalonexent | 113 [1] 113 💬
|
41 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
42 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
ROCK2 [1] ROCK2 💬
|
Fasudil Fasudil 💬
| Fasudil | 002 [4] 2 , 5 , 7 , 51 💬
|
43 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
RXRA [3] RXRA, RXRB, RXRG 💬
|
Acitretin Acitretin 💬
| Acitretin | 037 [1] 37 💬
|
44 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
RXRA [3] RXRA, RXRB, RXRG 💬
|
Alitretinoin Alitretinoin 💬
| Alitretinoin | 049 [1] 49 💬
|
45 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
RXRA [3] RXRA, RXRB, RXRG 💬
|
Bexarotene Bexarotene 💬
| Bexarotene | 013 [2] 13, 75 💬
|
46 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
47 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
48 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
49 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
SRC [1] SRC 💬
|
Saracatinib Saracatinib 💬
| Saracatinib | 006 [3] 6 , 89, 272 💬
|
50 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
51 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Certolizumab pegol Certolizumab pegol 💬
| Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
|
52 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
53 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
54 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
55 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
56 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Ozoralizumab Ozoralizumab 💬
| Ozoralizumab | 046 [1] 46 💬
|
57 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Pegsunercept Pegsunercept 💬
| Pegsunercept | 046 [1] 46 💬
|
58 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|