Target Gene/Pathway Pathway / Gene

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No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

1

cAMP signaling pathway 💬

[2] GIPR, GLP1R 💬

Tirzepatide 💬

[1] 233 💬

2

cAMP signaling pathway 💬

[1] GLP1R 💬

Dulaglutide 💬

[2] 13, 299 💬

3

cAMP signaling pathway 💬

[1] GLP1R 💬

[6] 6 , 17, 72, 78, 193, 233 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
17	Multiple system atrophy;MSA-C;MSA-P;
72	Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;
78	Hypopituitarism;Anterior pituitary hypothyroidism;
193	Prader-Willi syndrome;
233	Wolfram syndrome;Diabetes Insipidus, Diabetes mellitus, optic atrophy, and deafness syndrome;DIDMOAD syndrome;

4

cAMP signaling pathway 💬

[1] GLP1R 💬

Liraglutide 💬

[3] 6 , 75, 193 💬

5

cAMP signaling pathway 💬

[1] GLP1R 💬

Lixisenatide 💬

[1] 6 💬

6

cAMP signaling pathway 💬

[1] GLP1R 💬

Semaglutide 💬

[1] 6 💬

7

Insulin secretion 💬

[1] GLP1R 💬

Dulaglutide 💬

[2] 13, 299 💬

8

Insulin secretion 💬

[1] GLP1R 💬

[6] 6 , 17, 72, 78, 193, 233 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
17	Multiple system atrophy;MSA-C;MSA-P;
72	Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;
78	Hypopituitarism;Anterior pituitary hypothyroidism;
193	Prader-Willi syndrome;
233	Wolfram syndrome;Diabetes Insipidus, Diabetes mellitus, optic atrophy, and deafness syndrome;DIDMOAD syndrome;

9

Insulin secretion 💬

[1] GLP1R 💬

Liraglutide 💬

[3] 6 , 75, 193 💬

10

Insulin secretion 💬

[1] GLP1R 💬

Lixisenatide 💬

[1] 6 💬

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