Target Gene/Pathway Pathway / Gene

Search results

No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

1

Bile secretion 💬

[1] NR1H4 💬

Chenodeoxycholic acid

[4] 20, 96, 234, 263 💬

Disease ID	Name
20	Adrenoleukodystrophy;ALD;
96	Crohn disease;Terminal ileitis;
234	Peroxisomal disease (except Adrenoleukodystrophy);Peroxisomal disease;Peroxisomal disorder;Peroxisome biogenesis disorder;
263	Cerebrotendinous xanthomatosis;27-hydroxylase deficiency;CYP27 deficiency;

2

Bile secretion 💬

[1] NR1H4 💬

Cholic acid 💬

[4] 20, 234, 265, 310 💬

Disease ID	Name
20	Adrenoleukodystrophy;ALD;
234	Peroxisomal disease (except Adrenoleukodystrophy);Peroxisomal disease;Peroxisomal disorder;Peroxisome biogenesis disorder;
265	Lipodystrophy;
310	Congenital anomalies syndrome;

3

Bile secretion 💬

[1] NR1H4 💬

Obeticholic acid 💬

Obeticholic acid

[3] 93, 265, 296 💬

4

Bile secretion 💬

[1] NR1H4 💬

Tropifexor 💬

[1] 93 💬

5

Bile secretion 💬

[1] NR1H4 💬

Ursodeoxycholic acid

[14] 6 , 8 , 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
8	Huntington disease;Huntington chorea;
20	Adrenoleukodystrophy;ALD;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;
84	Sarcoidosis;
93	Primary biliary cholangitis;Primary biliary cirrhosis;PBC;
94	Primary sclerosing cholangitis;PSC;
95	Autoimmune hepatitis;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
234	Peroxisomal disease (except Adrenoleukodystrophy);Peroxisomal disease;Peroxisomal disorder;Peroxisome biogenesis disorder;
296	Biliary atresia;
299	Cystic fibrosis;