Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Alcoholism 💬
[3] MAOA, MAOB, SLC6A3 💬 Phentermine 💬 Phentermine [1] 97 💬
2 Alcoholism 💬
[1] SLC6A3 💬 Armodafinil 💬 Armodafinil [3]  6 , 13, 84 💬
3 Alcoholism 💬
[1] SLC6A3 💬 Bupropion 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
4 Alcoholism 💬
[1] SLC6A3 💬 Lisdexamfetamine 💬 Lisdexamfetamine [1] 13 💬
5 Alcoholism 💬
[1] SLC6A3 💬 Methylphenidate 💬 Methylphenidate [7]  6 , 13, 34, 84, 113, 179, 206 💬
6 Amphetamine addiction 💬
[3] MAOA, MAOB, SLC6A3 💬 Phentermine 💬 Phentermine [1] 97 💬
7 Amphetamine addiction 💬
[1] SLC6A3 💬 Armodafinil 💬 Armodafinil [3]  6 , 13, 84 💬
8 Amphetamine addiction 💬
[1] SLC6A3 💬 Bupropion 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
9 Amphetamine addiction 💬
[1] SLC6A3 💬 Lisdexamfetamine 💬 Lisdexamfetamine [1] 13 💬
10 Amphetamine addiction 💬
[1] SLC6A3 💬 Methylphenidate 💬 Methylphenidate [7]  6 , 13, 34, 84, 113, 179, 206 💬
11 Cocaine addiction 💬
[3] MAOA, MAOB, SLC6A3 💬 Phentermine 💬 Phentermine [1] 97 💬
12 Cocaine addiction 💬
[1] SLC6A3 💬 Armodafinil 💬 Armodafinil [3]  6 , 13, 84 💬
13 Cocaine addiction 💬
[1] SLC6A3 💬 Bupropion 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
14 Cocaine addiction 💬
[1] SLC6A3 💬 Lisdexamfetamine 💬 Lisdexamfetamine [1] 13 💬
15 Cocaine addiction 💬
[1] SLC6A3 💬 Methylphenidate 💬 Methylphenidate [7]  6 , 13, 34, 84, 113, 179, 206 💬
16 Dopaminergic synapse 💬
[3] MAOA, MAOB, SLC6A3 💬 Phentermine 💬 Phentermine [1] 97 💬
17 Dopaminergic synapse 💬
[1] SLC6A3 💬 Armodafinil 💬 Armodafinil [3]  6 , 13, 84 💬
18 Dopaminergic synapse 💬
[1] SLC6A3 💬 Bupropion 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
19 Dopaminergic synapse 💬
[1] SLC6A3 💬 Lisdexamfetamine 💬 Lisdexamfetamine [1] 13 💬
20 Dopaminergic synapse 💬
[1] SLC6A3 💬 Methylphenidate 💬 Methylphenidate [7]  6 , 13, 34, 84, 113, 179, 206 💬
21 Parkinson disease 💬
[3] MAOA, MAOB, SLC6A3 💬 Phentermine 💬 Phentermine [1] 97 💬
22 Parkinson disease 💬
[1] SLC6A3 💬 Armodafinil 💬 Armodafinil [3]  6 , 13, 84 💬
23 Parkinson disease 💬
[1] SLC6A3 💬 Bupropion 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
24 Parkinson disease 💬
[1] SLC6A3 💬 Lisdexamfetamine 💬 Lisdexamfetamine [1] 13 💬
25 Parkinson disease 💬
[1] SLC6A3 💬 Methylphenidate 💬 Methylphenidate [7]  6 , 13, 34, 84, 113, 179, 206 💬
26 Pathways of neurodegeneration - multiple diseases 💬
[1] SLC6A3 💬 Armodafinil 💬 Armodafinil [3]  6 , 13, 84 💬
27 Pathways of neurodegeneration - multiple diseases 💬
[1] SLC6A3 💬 Bupropion 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
28 Pathways of neurodegeneration - multiple diseases 💬
[1] SLC6A3 💬 Lisdexamfetamine 💬 Lisdexamfetamine [1] 13 💬
29 Pathways of neurodegeneration - multiple diseases 💬
[1] SLC6A3 💬 Methylphenidate 💬 Methylphenidate [7]  6 , 13, 34, 84, 113, 179, 206 💬
30 Pathways of neurodegeneration - multiple diseases 💬
[1] SLC6A3 💬 Phentermine 💬 Phentermine [1] 97 💬
31 Synaptic vesicle cycle 💬
[2] SLC6A2, SLC6A3 💬 Bupropion 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
32 Synaptic vesicle cycle 💬
[2] SLC6A2, SLC6A3 💬 Lisdexamfetamine 💬 Lisdexamfetamine [1] 13 💬
33 Synaptic vesicle cycle 💬
[2] SLC6A2, SLC6A3 💬 Methylphenidate 💬 Methylphenidate [7]  6 , 13, 34, 84, 113, 179, 206 💬
34 Synaptic vesicle cycle 💬
[3] SLC6A2, SLC6A3, SLC6A4 💬 Phentermine 💬 Phentermine [1] 97 💬
35 Synaptic vesicle cycle 💬
[1] SLC6A3 💬 Armodafinil 💬 Armodafinil [3]  6 , 13, 84 💬