124. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 12 / Drugs : 14 - (DrugBank : 5) / Drug target genes : 3 - Drug target pathways : 11
Drugs and their primary sponsors and trial info
6R-BH4
AZIENDA OSPEDALIERA OSPEDALE NIGUARDA CA' GRANDA (A.O. DI RILIEVO NAZIONALE)
2007 - EUCTR2007-004370-55-IT Italy;
ARICEPT 5*28 CPR
EISAI LTD UK
2005 - EUCTR2004-001162-40-IT Finland;Germany;Italy;Spain;Sweden;United Kingdom;
Antiplatelets
S. Andrea Hospital
2011 Phase 2 NCT01361763 Italy;
Aricept
Eisai Limited
2005 Phase 2 NCT00103948 Australia;Canada;Finland;France;Germany;Italy;Spain;Sweden;Switzerland;United Kingdom;United States;
Eisai Ltd
2005 Phase 2 EUCTR2004-001162-40-GB Finland;Germany;Italy;Spain;Sweden;United Kingdom;
2005 Phase 2 EUCTR2004-001162-40-FI Finland;Germany;Italy;Spain;Sweden;United Kingdom;
2005 Phase 2 EUCTR2004-001162-40-ES Finland;Germany;Italy;Spain;Sweden;United Kingdom;
2005 - EUCTR2004-001162-40-SE Finland;Germany;Italy;Spain;Sweden;United Kingdom;
- - EUCTR2004-001162-40-DE Finland;Germany;Italy;Spain;Sweden;United Kingdom;
Cilostazol
Mayo Clinic
2021 Phase 1/Phase 2 NCT04753970 United States;
Dabigatran
S. Andrea Hospital
2011 Phase 2 NCT01361763 Italy;
Donepezil
EISAI LTD UK
2005 - EUCTR2004-001162-40-IT Finland;Germany;Italy;Spain;Sweden;United Kingdom;
Donepezil hydrochloride
Eisai Ltd
2005 Phase 2 EUCTR2004-001162-40-GB Finland;Germany;Italy;Spain;Sweden;United Kingdom;
2005 Phase 2 EUCTR2004-001162-40-FI Finland;Germany;Italy;Spain;Sweden;United Kingdom;
2005 Phase 2 EUCTR2004-001162-40-ES Finland;Germany;Italy;Spain;Sweden;United Kingdom;
2005 - EUCTR2004-001162-40-SE Finland;Germany;Italy;Spain;Sweden;United Kingdom;
- - EUCTR2004-001162-40-DE Finland;Germany;Italy;Spain;Sweden;United Kingdom;
E2020
Eisai Ltd
2005 Phase 2 EUCTR2004-001162-40-GB Finland;Germany;Italy;Spain;Sweden;United Kingdom;
2005 Phase 2 EUCTR2004-001162-40-FI Finland;Germany;Italy;Spain;Sweden;United Kingdom;
2005 Phase 2 EUCTR2004-001162-40-ES Finland;Germany;Italy;Spain;Sweden;United Kingdom;
2005 - EUCTR2004-001162-40-SE Finland;Germany;Italy;Spain;Sweden;United Kingdom;
- - EUCTR2004-001162-40-DE Finland;Germany;Italy;Spain;Sweden;United Kingdom;
Fremanezumab
Mayo Clinic
2021 Phase 2 NCT04334408 United States;
HOV-12020 (Palm tocotrienols complex)
Hovid Berhad
2020 Phase 2 NCT04658823 France;
Phenoptin
AZIENDA OSPEDALIERA OSPEDALE NIGUARDA CA' GRANDA (A.O. DI RILIEVO NAZIONALE)
2007 - EUCTR2007-004370-55-IT Italy;
Sapropterin
AZIENDA OSPEDALIERA OSPEDALE NIGUARDA CA' GRANDA (A.O. DI RILIEVO NAZIONALE)
2007 - EUCTR2007-004370-55-IT Italy;
AZIENDA OSPEDALIERA OSPEDALE NIGUARDA CA' GRANDA (A.O. DI RILIEVO NAZIONALE)
2007 - EUCTR2007-004370-55-IT Italy;
ARICEPT 5*28 CPR
EISAI LTD UK
2005 - EUCTR2004-001162-40-IT Finland;Germany;Italy;Spain;Sweden;United Kingdom;
Antiplatelets
S. Andrea Hospital
2011 Phase 2 NCT01361763 Italy;
Aricept
Eisai Limited
2005 Phase 2 NCT00103948 Australia;Canada;Finland;France;Germany;Italy;Spain;Sweden;Switzerland;United Kingdom;United States;
Eisai Ltd
2005 Phase 2 EUCTR2004-001162-40-GB Finland;Germany;Italy;Spain;Sweden;United Kingdom;
2005 Phase 2 EUCTR2004-001162-40-FI Finland;Germany;Italy;Spain;Sweden;United Kingdom;
2005 Phase 2 EUCTR2004-001162-40-ES Finland;Germany;Italy;Spain;Sweden;United Kingdom;
2005 - EUCTR2004-001162-40-SE Finland;Germany;Italy;Spain;Sweden;United Kingdom;
- - EUCTR2004-001162-40-DE Finland;Germany;Italy;Spain;Sweden;United Kingdom;
Cilostazol
Mayo Clinic
2021 Phase 1/Phase 2 NCT04753970 United States;
Dabigatran
S. Andrea Hospital
2011 Phase 2 NCT01361763 Italy;
Donepezil
EISAI LTD UK
2005 - EUCTR2004-001162-40-IT Finland;Germany;Italy;Spain;Sweden;United Kingdom;
Donepezil hydrochloride
Eisai Ltd
2005 Phase 2 EUCTR2004-001162-40-GB Finland;Germany;Italy;Spain;Sweden;United Kingdom;
2005 Phase 2 EUCTR2004-001162-40-FI Finland;Germany;Italy;Spain;Sweden;United Kingdom;
2005 Phase 2 EUCTR2004-001162-40-ES Finland;Germany;Italy;Spain;Sweden;United Kingdom;
2005 - EUCTR2004-001162-40-SE Finland;Germany;Italy;Spain;Sweden;United Kingdom;
- - EUCTR2004-001162-40-DE Finland;Germany;Italy;Spain;Sweden;United Kingdom;
E2020
Eisai Ltd
2005 Phase 2 EUCTR2004-001162-40-GB Finland;Germany;Italy;Spain;Sweden;United Kingdom;
2005 Phase 2 EUCTR2004-001162-40-FI Finland;Germany;Italy;Spain;Sweden;United Kingdom;
2005 Phase 2 EUCTR2004-001162-40-ES Finland;Germany;Italy;Spain;Sweden;United Kingdom;
2005 - EUCTR2004-001162-40-SE Finland;Germany;Italy;Spain;Sweden;United Kingdom;
- - EUCTR2004-001162-40-DE Finland;Germany;Italy;Spain;Sweden;United Kingdom;
Fremanezumab
Mayo Clinic
2021 Phase 2 NCT04334408 United States;
HOV-12020 (Palm tocotrienols complex)
Hovid Berhad
2020 Phase 2 NCT04658823 France;
Phenoptin
AZIENDA OSPEDALIERA OSPEDALE NIGUARDA CA' GRANDA (A.O. DI RILIEVO NAZIONALE)
2007 - EUCTR2007-004370-55-IT Italy;
Sapropterin
AZIENDA OSPEDALIERA OSPEDALE NIGUARDA CA' GRANDA (A.O. DI RILIEVO NAZIONALE)
2007 - EUCTR2007-004370-55-IT Italy;