166. Pseudoxanthoma elasticum Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 16 / Drugs : 27 - (DrugBank : 5) / Drug target genes : 5 - Drug target pathways : 28
Drugs and their primary sponsors and trial info
Aflibercept
University Hospital, Bonn
2015 Phase 2 NCT02537054 Germany;
CAS No.: 7758-16-9
Tampere university hospital
2018 Phase 2;Phase 3 EUCTR2018-001492-20-FI Finland;
Disodium Pyrophosphate
Tampere University Hospital
2020 Phase 2 NCT04441671 -
Disodiumpyrophosphate
Tampere University Hospital
2019 Phase 2 EUCTR2019-002109-24-FI Finland;
Eylea
Medizinische Fakultät der Universität Bonn
2015 Phase 2 EUCTR2014-005263-33-DE Germany;
INZ-701
Inozyme Pharma
2021 Phase 1/Phase 2 NCT05030831 United Kingdom;United States;
Inozyme Pharma, Inc.
2021 Phase 1;Phase 2 EUCTR2020-004000-33-FR France;
Intravitreal injection ranibizumab
University Hospital, Bonn
2007 Phase 2 NCT00510965 Germany;
Lansolprazole
Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud (FIMABIS)
2018 Phase 2 EUCTR2016-004021-16-ES Spain;
Lansoprazole
Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
2020 Phase 4 NCT04660461 Spain;
Lucentis
Department of Ophthalmology, Bonn University
2007 Phase 2 EUCTR2006-006231-49-DE Germany;
Novartis Pharma S.A.S
2013 Phase 3 EUCTR2013-001421-55-FR France;
RECOMBINANT HUMAN ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 FUSED TO THE FC FRAGMENT OF IGG1
Inozyme Pharma, Inc.
2021 Phase 1;Phase 2 EUCTR2020-004000-33-FR France;
RFB002, rhuFab V2
Department of Ophthalmology, Bonn University
2007 Phase 2 EUCTR2006-006231-49-DE Germany;
RFB002A
Novartis Pharma S.A.S
2013 Phase 3 EUCTR2013-001421-55-FR France;
Ranibizumab
Department of Ophthalmology, Bonn University
2007 Phase 2 EUCTR2006-006231-49-DE Germany;
Ranibizumab injection (0.5 mg)
Manhattan Eye, Ear & Throat Hospital
2007 Phase 1/Phase 2 NCT00470977 United States;
SODIUM ACID PYROPHOSPHATE SAPP ROR 28 FOOD GRADE
Tampere university hospital
2018 Phase 2;Phase 3 EUCTR2018-001492-20-FI Finland;
Study comparator ETI
Centre Hospitalier Universitaire de Nice
2021 Phase 2 NCT04868578 France;
Study treatment PPI
Centre Hospitalier Universitaire de Nice
2021 Phase 2 NCT04868578 France;
University Hospital, Bonn
2015 Phase 2 NCT02537054 Germany;
CAS No.: 7758-16-9
Tampere university hospital
2018 Phase 2;Phase 3 EUCTR2018-001492-20-FI Finland;
Disodium Pyrophosphate
Tampere University Hospital
2020 Phase 2 NCT04441671 -
Disodiumpyrophosphate
Tampere University Hospital
2019 Phase 2 EUCTR2019-002109-24-FI Finland;
Eylea
Medizinische Fakultät der Universität Bonn
2015 Phase 2 EUCTR2014-005263-33-DE Germany;
INZ-701
Inozyme Pharma
2021 Phase 1/Phase 2 NCT05030831 United Kingdom;United States;
Inozyme Pharma, Inc.
2021 Phase 1;Phase 2 EUCTR2020-004000-33-FR France;
Intravitreal injection ranibizumab
University Hospital, Bonn
2007 Phase 2 NCT00510965 Germany;
Lansolprazole
Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud (FIMABIS)
2018 Phase 2 EUCTR2016-004021-16-ES Spain;
Lansoprazole
Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
2020 Phase 4 NCT04660461 Spain;
Lucentis
Department of Ophthalmology, Bonn University
2007 Phase 2 EUCTR2006-006231-49-DE Germany;
Novartis Pharma S.A.S
2013 Phase 3 EUCTR2013-001421-55-FR France;
RECOMBINANT HUMAN ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 FUSED TO THE FC FRAGMENT OF IGG1
Inozyme Pharma, Inc.
2021 Phase 1;Phase 2 EUCTR2020-004000-33-FR France;
RFB002, rhuFab V2
Department of Ophthalmology, Bonn University
2007 Phase 2 EUCTR2006-006231-49-DE Germany;
RFB002A
Novartis Pharma S.A.S
2013 Phase 3 EUCTR2013-001421-55-FR France;
Ranibizumab
Department of Ophthalmology, Bonn University
2007 Phase 2 EUCTR2006-006231-49-DE Germany;
Ranibizumab injection (0.5 mg)
Manhattan Eye, Ear & Throat Hospital
2007 Phase 1/Phase 2 NCT00470977 United States;
SODIUM ACID PYROPHOSPHATE SAPP ROR 28 FOOD GRADE
Tampere university hospital
2018 Phase 2;Phase 3 EUCTR2018-001492-20-FI Finland;
Study comparator ETI
Centre Hospitalier Universitaire de Nice
2021 Phase 2 NCT04868578 France;
Study treatment PPI
Centre Hospitalier Universitaire de Nice
2021 Phase 2 NCT04868578 France;