202. Smith-Magenis syndrome Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 9 / Drugs : 10 - (DrugBank : 5) / Drug target genes : 4 - Drug target pathways : 7
Drugs and their primary sponsors and trial info
Acylated and unacylated ghrelin dosages
University Hospital, Toulouse
2021 - NCT04768803 -
DTR Melatonin (NIH CC PDS)
National Human Genome Research Institute (NHGRI)
2007 Phase 1 NCT00506259 United States;
Enviro-light artificial light box
Oregon Health and Science University
1998 - NCT00691574 United States;
Hourly dosing of the nychtemeral secretion of melatonin
Hôpital le Vinatier
2018 - NCT03492970 France;
Melatonin
Oregon Health and Science University
1998 - NCT00691574 United States;
Melatonin CR
National Human Genome Research Institute (NHGRI)
2007 Phase 1 NCT00506259 United States;
Phototherapy (Bright Light)
National Human Genome Research Institute (NHGRI)
2007 Phase 1 NCT00506259 United States;
RM-493
Rhythm Pharmaceuticals, Inc.
2020 Phase 2 EUCTR2017-000387-14-GR Canada;France;Germany;Greece;Israel;Netherlands;Spain;United Kingdom;United States;
2017 Phase 2 EUCTR2017-000387-14-GB Canada;France;Germany;Greece;Israel;Netherlands;Spain;United Kingdom;United States;
- Phase 2 EUCTR2017-000387-14-FR Australia;Canada;France;Germany;Greece;Ireland;Israel;Netherlands;Portugal;Spain;Turkey;United Kingdom;United States;
Setmelanotide
Rhythm Pharmaceuticals, Inc.
2020 Phase 2 EUCTR2017-000387-14-GR Canada;France;Germany;Greece;Israel;Netherlands;Spain;United Kingdom;United States;
2017 Phase 2/Phase 3 NCT03013543 Canada;France;Germany;Greece;Israel;Netherlands;Spain;United Kingdom;United States;
2017 Phase 2 EUCTR2017-000387-14-GB Canada;France;Germany;Greece;Israel;Netherlands;Spain;United Kingdom;United States;
- Phase 2 EUCTR2017-000387-14-FR Australia;Canada;France;Germany;Greece;Ireland;Israel;Netherlands;Portugal;Spain;Turkey;United Kingdom;United States;
Tasimelteon
Vanda Pharmaceuticals
2016 Phase 1 NCT02776215 United States;
2015 Phase 2/Phase 3 NCT02231008 United States;
University Hospital, Toulouse
2021 - NCT04768803 -
DTR Melatonin (NIH CC PDS)
National Human Genome Research Institute (NHGRI)
2007 Phase 1 NCT00506259 United States;
Enviro-light artificial light box
Oregon Health and Science University
1998 - NCT00691574 United States;
Hourly dosing of the nychtemeral secretion of melatonin
Hôpital le Vinatier
2018 - NCT03492970 France;
Melatonin
Oregon Health and Science University
1998 - NCT00691574 United States;
Melatonin CR
National Human Genome Research Institute (NHGRI)
2007 Phase 1 NCT00506259 United States;
Phototherapy (Bright Light)
National Human Genome Research Institute (NHGRI)
2007 Phase 1 NCT00506259 United States;
RM-493
Rhythm Pharmaceuticals, Inc.
2020 Phase 2 EUCTR2017-000387-14-GR Canada;France;Germany;Greece;Israel;Netherlands;Spain;United Kingdom;United States;
2017 Phase 2 EUCTR2017-000387-14-GB Canada;France;Germany;Greece;Israel;Netherlands;Spain;United Kingdom;United States;
- Phase 2 EUCTR2017-000387-14-FR Australia;Canada;France;Germany;Greece;Ireland;Israel;Netherlands;Portugal;Spain;Turkey;United Kingdom;United States;
Setmelanotide
Rhythm Pharmaceuticals, Inc.
2020 Phase 2 EUCTR2017-000387-14-GR Canada;France;Germany;Greece;Israel;Netherlands;Spain;United Kingdom;United States;
2017 Phase 2/Phase 3 NCT03013543 Canada;France;Germany;Greece;Israel;Netherlands;Spain;United Kingdom;United States;
2017 Phase 2 EUCTR2017-000387-14-GB Canada;France;Germany;Greece;Israel;Netherlands;Spain;United Kingdom;United States;
- Phase 2 EUCTR2017-000387-14-FR Australia;Canada;France;Germany;Greece;Ireland;Israel;Netherlands;Portugal;Spain;Turkey;United Kingdom;United States;
Tasimelteon
Vanda Pharmaceuticals
2016 Phase 1 NCT02776215 United States;
2015 Phase 2/Phase 3 NCT02231008 United States;