203. 22q11.2 deletion syndrome Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 5 / Drugs : 7 - (DrugBank : 1) / Drug target genes : 14 - Drug target pathways : 23
22q11.2 deletion syndrome and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 203 | 22q11.2 deletion syndrome | - |
| 13 | Multiple sclerosis/Neuromyelitis optica | 14.000 |
| 6 | Parkinson disease | 14.000 |
| 17 | Multiple system atrophy | 14.000 |
| 8 | Huntington disease | 14.000 |
| 5 | Progressive supranuclear palsy | 14.000 |
| 156 | Rett syndrome | 14.000 |
| 97 | Ulcerative colitis | 14.000 |
| 206 | Fragile X syndrome | 14.000 |
| 3 | Spinal muscular atrophy | 14.000 |
| 18 | Spinocerebellar degeneration | 14.000 |
| 2 | Amyotrophic lateral sclerosis | 14.000 |
| 140 | Dorabe syndrome | 6.388 |
| 144 | Lennox-Gastaut syndrome | 6.376 |
| 193 | Prader-Willi syndrome | 6.353 |
| 215 | Tetralogy of Fallot | 2.679 |
| 4 | Primary lateral sclerosis | 2.632 |
| 205 | Fragile X syndrome related disease | 2.429 |
| 127 | Frontotemporal lobar degeneration | 2.188 |
| 78 | Hypopituitarism | 2.151 |
| 21 | Mitochondrial disease | 2.128 |
| 113 | Muscular dystrophy | 2.058 |
| 70 | Spinal stenosis | 2.029 |
| 85 | Idiopathic interstitial pneumonia | 1.948 |
| 49 | Systemic lupus erythematosus | 1.927 |
| 96 | Crohn disease | 1.881 |
| 46 | Malignant rheumatoid arthritis | 1.873 |