215. Tetralogy of Fallot Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 18 / Drugs : 26 - (DrugBank : 14) / Drug target genes : 13 - Drug target pathways : 45
Drugs and their primary sponsors and trial info
AS
Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College
2020 - ChiCTR2000033234 China;
B-lines SE
Fatebenefratelli Hospital
2016 - NCT03049995 Italy;
CPX
Klinik für Kardiologie, Pneumologie und Angiologie
2018 - NCT03835494 Germany;
Calcium gluconate
National Center for Research Resources (NCRR)
1995 - NCT00004361 -
Cardiac MRI
Bernhard Kuhn
2022 Phase 1 NCT04713657 United States;
Cellvizio 100 Series System with Confocal Miniprobes
Aditya Kaza
2019 Phase 2 NCT04017975 United States;
Coenzyme Q10
Fuwai Central China Cardiovascualr Hospital
2019 Phase 0 ChiCTR1900025513 China;
Cold Cadioplegia
Ain Shams University
2021 Early Phase 1 NCT05176782 Egypt;
Coronary flow reserve SE
Fatebenefratelli Hospital
2016 - NCT03049995 Italy;
Dexmedetomidine
Athena Zuppa
2004 Phase 1 NCT00573066 -
HealthCore-NERI
2014 Phase 1 NCT01915277 United States;
Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University
2016 - ChiCTR-IOR-16008571 China;
Diastolic function SE
Fatebenefratelli Hospital
2016 - NCT03049995 Italy;
Dobutamin
Competence Network for Congenital Heart Defects
2007 Phase 3 NCT00564993 Germany;
Dobutamine
Deutsche Herzzentrum Berlin, Kompetenznetz Angeborene Herzfehler
2007 - EUCTR2007-003461-41-DE Germany;
University Hospital Tuebingen
2007 - NCT00557934 Germany;
Echocardiogram
Bernhard Kuhn
2022 Phase 1 NCT04713657 United States;
Eplerenone
Washington University School of Medicine
2013 Phase 4 NCT01971593 United States;
Fentanyl (High Dose)
Nationwide Children's Hospital
2008 Phase 2 NCT00848393 United States;
Fentanyl (Low Dose)
Nationwide Children's Hospital
2008 Phase 2 NCT00848393 United States;
Fentanyl (Low Dose) + Dexmedetomidine
Nationwide Children's Hospital
2008 Phase 2 NCT00848393 United States;
Fluorescite
Aditya Kaza
2019 Phase 2 NCT04017975 United States;
HTK cardioplegia
Ain Shams University
2021 Early Phase 1 NCT05176782 Egypt;
Ketamine
Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University
2016 - ChiCTR-IOR-16008571 China;
Left ventricular contractile reserve SE
Fatebenefratelli Hospital
2016 - NCT03049995 Italy;
Left ventricular outflow tract gradient SE
Fatebenefratelli Hospital
2016 - NCT03049995 Italy;
Losartan
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
2013 Phase 2 NCT02010905 Netherlands;
Mitral regurgitation SE
Fatebenefratelli Hospital
2016 - NCT03049995 Italy;
Physical Exam
Bernhard Kuhn
2022 Phase 1 NCT04713657 United States;
Propranolol Hydrochloride
Bernhard Kuhn
2022 Phase 1 NCT04713657 United States;
Pulmonary hemodynamics SE
Fatebenefratelli Hospital
2016 - NCT03049995 Italy;
Recombinant human brain natriuretic peptide (rhBNP)
Shanghai Jiao Tong University School of Medicine
2013 - NCT01941576 China;
Sodium citrate
National Center for Research Resources (NCRR)
1995 - NCT00004361 -
Sulfur Hexafluoride Lipid Type A Microspheres 25 MG Injection Powder for Suspension [LUMASON]
Nemours Children's Health System
2022 Phase 1/Phase 2 NCT05186415 -
TOF repair with trans-annular patch VS preservation of PV
Assiut University
2018 - NCT03732742 -
Thymidine
Bernhard Kuhn
2022 Phase 1 NCT04713657 United States;
Tranexamic acid
National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
2018 - ChiCTR1800019578 China;
Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College
2020 - ChiCTR2000033234 China;
B-lines SE
Fatebenefratelli Hospital
2016 - NCT03049995 Italy;
CPX
Klinik für Kardiologie, Pneumologie und Angiologie
2018 - NCT03835494 Germany;
Calcium gluconate
National Center for Research Resources (NCRR)
1995 - NCT00004361 -
Cardiac MRI
Bernhard Kuhn
2022 Phase 1 NCT04713657 United States;
Cellvizio 100 Series System with Confocal Miniprobes
Aditya Kaza
2019 Phase 2 NCT04017975 United States;
Coenzyme Q10
Fuwai Central China Cardiovascualr Hospital
2019 Phase 0 ChiCTR1900025513 China;
Cold Cadioplegia
Ain Shams University
2021 Early Phase 1 NCT05176782 Egypt;
Coronary flow reserve SE
Fatebenefratelli Hospital
2016 - NCT03049995 Italy;
Dexmedetomidine
Athena Zuppa
2004 Phase 1 NCT00573066 -
HealthCore-NERI
2014 Phase 1 NCT01915277 United States;
Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University
2016 - ChiCTR-IOR-16008571 China;
Diastolic function SE
Fatebenefratelli Hospital
2016 - NCT03049995 Italy;
Dobutamin
Competence Network for Congenital Heart Defects
2007 Phase 3 NCT00564993 Germany;
Dobutamine
Deutsche Herzzentrum Berlin, Kompetenznetz Angeborene Herzfehler
2007 - EUCTR2007-003461-41-DE Germany;
University Hospital Tuebingen
2007 - NCT00557934 Germany;
Echocardiogram
Bernhard Kuhn
2022 Phase 1 NCT04713657 United States;
Eplerenone
Washington University School of Medicine
2013 Phase 4 NCT01971593 United States;
Fentanyl (High Dose)
Nationwide Children's Hospital
2008 Phase 2 NCT00848393 United States;
Fentanyl (Low Dose)
Nationwide Children's Hospital
2008 Phase 2 NCT00848393 United States;
Fentanyl (Low Dose) + Dexmedetomidine
Nationwide Children's Hospital
2008 Phase 2 NCT00848393 United States;
Fluorescite
Aditya Kaza
2019 Phase 2 NCT04017975 United States;
HTK cardioplegia
Ain Shams University
2021 Early Phase 1 NCT05176782 Egypt;
Ketamine
Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University
2016 - ChiCTR-IOR-16008571 China;
Left ventricular contractile reserve SE
Fatebenefratelli Hospital
2016 - NCT03049995 Italy;
Left ventricular outflow tract gradient SE
Fatebenefratelli Hospital
2016 - NCT03049995 Italy;
Losartan
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
2013 Phase 2 NCT02010905 Netherlands;
Mitral regurgitation SE
Fatebenefratelli Hospital
2016 - NCT03049995 Italy;
Physical Exam
Bernhard Kuhn
2022 Phase 1 NCT04713657 United States;
Propranolol Hydrochloride
Bernhard Kuhn
2022 Phase 1 NCT04713657 United States;
Pulmonary hemodynamics SE
Fatebenefratelli Hospital
2016 - NCT03049995 Italy;
Recombinant human brain natriuretic peptide (rhBNP)
Shanghai Jiao Tong University School of Medicine
2013 - NCT01941576 China;
Sodium citrate
National Center for Research Resources (NCRR)
1995 - NCT00004361 -
Sulfur Hexafluoride Lipid Type A Microspheres 25 MG Injection Powder for Suspension [LUMASON]
Nemours Children's Health System
2022 Phase 1/Phase 2 NCT05186415 -
TOF repair with trans-annular patch VS preservation of PV
Assiut University
2018 - NCT03732742 -
Thymidine
Bernhard Kuhn
2022 Phase 1 NCT04713657 United States;
Tranexamic acid
National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
2018 - ChiCTR1800019578 China;