DR info

Clinical trials : 44 / Drugs : 22 - (DrugBank : 7) / Drug target genes : 3 - Drug target pathways : 14

Drugs and their primary sponsors and trial info

00201600
   SAVARA APS
      2020   Phase 3   EUCTR2020-001263-85-IT   Belgium;Canada;France;Germany;Ireland;Italy;Japan;Korea, Democratic People's Republic of;Korea, Republic of;Netherlands;Poland;Romania;Turkey;United Kingdom;United States;
Blood collection
   Assistance Publique - Hôpitaux de Paris
      2021   -   NCT04811274   France;
Bronchoalveolar lavage fluid collection
   Assistance Publique - Hôpitaux de Paris
      2021   -   NCT04811274   France;
Centricyte 1000
   Black Tie Medical, Inc.
      2020   Early Phase 1   NCT04326036   United States;
GM-CSF
   Dai Huaping
      2016   Phase 2   NCT03316651   China;
   Peking Union Medical College Hospital
      2014   Phase 2   NCT02243228   China;
GM-CSF (granulocyte-macrophage colony-stimulating factor, sargramostim)
   The Cleveland Clinic
      2001   Phase 2   NCT00030056   United States;
GM-CSF [Leukine (Sargramostim)]
   IRCCS Policlinico S. Matteo
      2009   Phase 2/Phase 3   NCT00901511   Italy;
GM-CSF inhalation therapy
   Koh Nakata
      2016   Phase 2-3   JPRN-JMA-IIA00205   Japan;
Granulocyte-macrophage colony stimulating factor (GM-CSF)
   Koh Nakata, M.D., Ph.D.Bioscience Medical Research Center (BMRC), Niigata University Medical & Dental Hospital
      -   Phase 2   JPRN-JMA-IIA00013   Japan;
Homocysteine
   Assistance Publique - Hôpitaux de Paris
      2019   Phase 1/Phase 2   NCT03887169   France;
IV Deployment Of cSVF In Sterile Normal Saline IV Solution
   Black Tie Medical, Inc.
      2020   Early Phase 1   NCT04326036   United States;
Leukine
   Children's Hospital Medical Center, Cincinnati
      2012   Phase 2   NCT01511068   United States;
   OSPEDALE POLICLINICO S. MATTEO
      2008   -   EUCTR2008-007086-23-IT   Italy;
Liberase Enzyme (Roche)
   Black Tie Medical, Inc.
      2020   Early Phase 1   NCT04326036   United States;
Methionine
   Assistance Publique - Hôpitaux de Paris
      2019   Phase 1/Phase 2   NCT03887169   France;
Microcannula Harvest Adipose Derived tissue stromal vascular fraction (tSVF)
   Black Tie Medical, Inc.
      2020   Early Phase 1   NCT04326036   United States;
Molgramostim
   Savara Inc.
      2021   Phase 3   NCT04544293   Australia;Belgium;Canada;France;Germany;Greece;Ireland;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Romania;Russian Federation;Spain;Turkey;United Kingdom;United States;
      2018   Phase 3   NCT03482752   Denmark;France;Germany;Greece;Israel;Italy;Netherlands;Russian Federation;Turkey;United Kingdom;
      2016   Phase 2/Phase 3   NCT02702180   Australia;Denmark;France;Germany;Greece;Israel;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Romania;Russian Federation;Slovakia;Spain;Switzerland;Turkey;United Kingdom;United States;
      2015   Phase 1   NCT02468908   United Kingdom;
Molgramostim 300 mcg nebuliser solution
   Savara ApS
      2018   Phase 2;Phase 3   EUCTR2015-003878-33-PT   Australia;Denmark;France;Germany;Greece;Israel;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Turkey;United Kingdom;United States;
      2016   Phase 2;Phase 3   EUCTR2015-003878-33-NL   Belgium;Denmark;France;Germany;Greece;Israel;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Turkey;United Kingdom;United States;
      2016   Phase 2;Phase 3   EUCTR2015-003878-33-IT   Denmark;France;Germany;Greece;Israel;Italy;Japan;Netherlands;Portugal;Russian Federation;Spain;Switzerland;United Kingdom;
      2016   Phase 2;Phase 3   EUCTR2015-003878-33-GB   Australia;Denmark;France;Germany;Greece;Israel;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Romania;Russian Federation;Slovakia;Spain;Switzerland;Turkey;United Kingdom;United States;
      2016   Phase 2;Phase 3   EUCTR2015-003878-33-ES   Denmark;France;Germany;Greece;Israel;Italy;Japan;Netherlands;Portugal;Russian Federation;Spain;Switzerland;United Kingdom;
      2016   Phase 2;Phase 3   EUCTR2015-003878-33-DE   Australia;Denmark;France;Germany;Greece;Israel;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Turkey;United Kingdom;United States;
      2015   Phase 2;Phase 3   EUCTR2015-003878-33-DK   Belgium;Denmark;France;Germany;Greece;Israel;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Turkey;United Kingdom;United States;
   Serendex Pharmaceuticals A/S
      2016   Phase 2;Phase 3   EUCTR2015-003878-33-GR   Belgium;Denmark;France;Germany;Greece;Israel;Italy;Japan;Netherlands;Portugal;Russian Federation;Spain;Switzerland;United Kingdom;
Molgramostim 300 µg nebulizer solution
   SAVARA APS
      2020   Phase 3   EUCTR2020-001263-85-IT   Belgium;Canada;France;Germany;Ireland;Italy;Japan;Korea, Democratic People's Republic of;Korea, Republic of;Netherlands;Poland;Romania;Turkey;United Kingdom;United States;
   Savara ApS
      2021   Phase 3   EUCTR2020-001263-85-NL   Belgium;Canada;France;Germany;Ireland;Italy;Japan;Korea, Republic of;Netherlands;Poland;Romania;Turkey;United Kingdom;United States;
      2021   Phase 3   EUCTR2020-001263-85-IE   Belgium;Canada;France;Germany;Ireland;Italy;Japan;Korea, Republic of;Netherlands;Poland;Romania;Turkey;United Kingdom;United States;
      2021   Phase 3   EUCTR2020-001263-85-DE   Belgium;Canada;France;Germany;Ireland;Italy;Japan;Korea, Republic of;Netherlands;Poland;Romania;Turkey;United Kingdom;United States;
      2021   Phase 3   EUCTR2020-001263-85-BE   Belgium;Canada;France;Germany;Ireland;Italy;Japan;Korea, Republic of;Netherlands;Poland;Romania;Turkey;United Kingdom;United States;
      2020   Phase 3   EUCTR2020-001263-85-PL   Belgium;Canada;France;Germany;Ireland;Italy;Japan;Korea, Republic of;Netherlands;Poland;Romania;Turkey;United Kingdom;United States;
Molgramostim Nebuliser solution 300 mcg
   Savara ApS
      2019   Phase 3   EUCTR2017-004078-32-IT   Denmark;France;Germany;Greece;Israel;Italy;Netherlands;Russian Federation;United Kingdom;
      2018   Phase 3   EUCTR2017-004078-32-NL   Denmark;France;Germany;Greece;Israel;Italy;Netherlands;Russian Federation;United Kingdom;
      2018   Phase 3   EUCTR2017-004078-32-GR   Denmark;France;Germany;Greece;Israel;Italy;Netherlands;Russian Federation;United Kingdom;
      2018   Phase 3   EUCTR2017-004078-32-GB   Denmark;France;Germany;Greece;Israel;Italy;Netherlands;Russian Federation;United Kingdom;
      2018   Phase 3   EUCTR2017-004078-32-FR   Denmark;France;Germany;Greece;Israel;Italy;Netherlands;Russian Federation;United Kingdom;
      2018   Phase 3   EUCTR2017-004078-32-DK   Denmark;France;Germany;Greece;Israel;Italy;Netherlands;Russian Federation;United Kingdom;
      2018   Phase 3   EUCTR2017-004078-32-DE   Denmark;France;Germany;Greece;Israel;Italy;Netherlands;Russian Federation;United Kingdom;
Pioglitazone
   Children's Hospital Medical Center, Cincinnati
      2017   Phase 1   NCT03231033   United States;
Rituximab
   East Carolina University
      2007   Phase 2   NCT00552461   United States;
   National Institute of Allergy and Infectious Diseases (NIAID)
      2014   Phase 1   NCT01842386   United States;
Sargramostim
   Children's Hospital Medical Center, Cincinnati
      2017   Phase 1   NCT03006146   United States;
   Niigata University Medical & Dental Hospital
      2016   Phase 2   NCT02835742   Japan;
      2016   Phase 1   NCT02840708   Japan;
   OSPEDALE POLICLINICO S. MATTEO
      2008   -   EUCTR2008-007086-23-IT   Italy;
Sterile Normal Saline for Intravenous Use
   Black Tie Medical, Inc.
      2020   Early Phase 1   NCT04326036   United States;
Vitamin B12, B9, B6, C supplementation
   Assistance Publique - Hôpitaux de Paris
      2019   Phase 1/Phase 2   NCT03887169   France;
WLL
   IRCCS Policlinico S. Matteo
      2009   Phase 2/Phase 3   NCT00901511   Italy;
Whole Lung Lavage(WLL)
   Shanghai Pulmonary Hospital, Shanghai, China
      2012   Phase 2   NCT01983657   China;