231. Alpha-1-antitrypsin deficiency Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 93 / Drugs : 77 - (DrugBank : 8) / Drug target genes : 10 - Drug target pathways : 36
Alpha-1-antitrypsin deficiency and other diseases between which drug repositioning might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Drug repositionability
ID | Diseases (Sorted by drug repositionability) |
---|---|
231 | Alpha-1-antitrypsin deficiency |
6 | Parkinson disease |
97 | Ulcerative colitis |
13 | Multiple sclerosis/Neuromyelitis optica |
70 | Spinal stenosis |
96 | Crohn disease |
298 | Hereditary pancreatitis |
46 | Malignant rheumatoid arthritis |
2 | Amyotrophic lateral sclerosis |
36 | Epidermolysis bullosa |
34 | Neurofibromatosis |
140 | Dorabe syndrome |
22 | Moyamoya disease |
144 | Lennox-Gastaut syndrome |
193 | Prader-Willi syndrome |
152 | PCDH19 related syndrome |
158 | Tuberous sclerosis |
156 | Rett syndrome |
84 | Sarcoidosis |
8 | Huntington disease |
201 | Angelman syndrome |
3 | Spinal muscular atrophy |
75 | Cushing disease |
205 | Fragile X syndrome related disease |
5 | Progressive supranuclear palsy |
296 | Biliary atresia |
272 | Fibrodysplasia ossificans progressiva |
21 | Mitochondrial disease |
145 | West syndrome |
206 | Fragile X syndrome |
155 | Acquired aphasia with convulsive disorder |
98 | Eosinophilic gastrointestinal disease |
17 | Multiple system atrophy |
18 | Spinocerebellar degeneration |
10 | Charcot-Marie-Tooth disease |
107 | Juvenile idiopathic arthritis |
1 | Spinal and bulbar muscular atrophy |
226 | Interstitial cystitis with Hunners ulcer |
256 | Muscle glycogenosis |
168 | Ehlers-Danlos syndrome |
86 | Pulmonary arterial hypertension |
51 | Scleroderma |
113 | Muscular dystrophy |
58 | Hypertrophic cardiomyopathy |
38 | Stevens-Johnson syndrome |
53 | Sjogren syndrome |
337 | Homocystinuria |
114 | Non-dystrophic myotonia syndrome |
28 | Systemic amyloidosis |
127 | Frontotemporal lobar degeneration |
251 | Urea cycle disorder |
111 | Congenital myopathy |