233. Wolfram syndrome Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 11 / Drugs : 17 - (DrugBank : 8) / Drug target genes : 12 - Drug target pathways : 41
Wolfram syndrome and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 233 | Wolfram syndrome | - |
| 6 | Parkinson disease | 11.000 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 9.125 |
| 127 | Frontotemporal lobar degeneration | 7.732 |
| 65 | Primary immunodeficiency | 7.527 |
| 2 | Amyotrophic lateral sclerosis | 7.449 |
| 102 | Rubinstein-Taybi syndrome | 7.000 |
| 89 | Lymphangioleiomyomatosis | 5.114 |
| 256 | Muscle glycogenosis | 5.029 |
| 331 | Idiopathic multicentric castleman disease | 5.029 |
| 26 | HTLV-1-associated myelopathy | 4.923 |
| 90 | Retinitis pigmentosa | 4.818 |
| 3 | Spinal muscular atrophy | 4.791 |
| 222 | Primary nephrotic syndrome | 4.747 |
| 5 | Progressive supranuclear palsy | 4.729 |
| 34 | Neurofibromatosis | 4.659 |
| 85 | Idiopathic interstitial pneumonia | 4.635 |
| 86 | Pulmonary arterial hypertension | 2.409 |
| 77 | Growth hormone secreting pituitary adenoma | 2.000 |
| 75 | Cushing disease | 1.619 |
| 299 | Cystic fibrosis | 1.561 |
| 149 | Hemiconvulsion hemiplegia epilepsy syndrome | 1.203 |
| 215 | Tetralogy of Fallot | 1.182 |
| 158 | Tuberous sclerosis | 1.005 |