241. Hypertyrosinemia type I Disease details / Clinical trials / Drug dev / DR info


Clinical trials : 14 Drugs : 7 - (DrugBank : 1) / Drug target gene : 1 - Drug target pathways : 5

Drugs and their primary sponsors and trial info
NTBC   
   National Center for Research Resources (NCRR)
      1994   Phase 2   NCT00004333   -
   University of Washington
      1998   -   NCT00004443   Canada;United States;
Nitisinone   
   Cycle Pharmaceuticals Ltd.
      2015   Phase 1   NCT02750332   South Africa;
   Sutphin Drugs
      2019   -   NCT04113772   India;
   Swedish Orphan Biovitrum
      2014   Phase 3   NCT02323529   Belgium;Denmark;France;Germany;Sweden;
      2013   -   NCT02320084   Austria;Belgium;Croatia;Czech Republic;Czechia;Denmark;Finland;France;Germany;Greece;Hungary;Ireland;Italy;Kosovo;Lithuania;Macedonia, The Former Yugoslav Republic of;Netherlands;Norway;Poland;Portugal;Romania;Slovakia;Spain;Sweden;Switzerland;United Kingdom;
      2012   Phase 1   NCT01734889   France;Germany;United Kingdom;
   Swedish Orphan Biovitrum AB
      2012   -   EUCTR2012-002286-36-DE   Germany;United Kingdom;
Nitisinone 10 mg Tablet High Compritol   
   Cycle Pharmaceuticals Ltd.
      2015   Phase 1   NCT02750709   South Africa;
Nitisinone Baked Tablet   
   Cycle Pharmaceuticals Ltd.
      2016   Phase 1   NCT02750345   South Africa;
Orfadin   
   Cycle Pharmaceuticals Ltd.
      2016   Phase 1   NCT02750345   South Africa;
      2015   Phase 1   NCT02750709   South Africa;
   Sutphin Drugs
      2019   -   NCT04113772   India;
   Swedish Orphan Biovitrum AB (Publ)
      2014   Phase 4   EUCTR2013-004132-29-BE   Belgium;Denmark;Sweden;
      2014   -   EUCTR2013-004132-29-SE   Belgium;Denmark;Sweden;
      2014   -   EUCTR2013-004132-29-DK   Belgium;Denmark;Sweden;
Orfadin oral suspension 4mg/ml   
   Swedish Orphan Biovitrum AB
      2012   -   EUCTR2012-002286-36-GB   Germany;United Kingdom;
      2012   -   EUCTR2012-002286-36-DE   Germany;United Kingdom;