241. Hypertyrosinemia type I Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 14 / Drugs : 7 - (DrugBank : 1) / Drug target gene : 1 - Drug target pathways : 5
Drugs and their primary sponsors and trial info
NTBC
National Center for Research Resources (NCRR)
1994 Phase 2 NCT00004333 -
University of Washington
1998 - NCT00004443 Canada;United States;
Nitisinone
Cycle Pharmaceuticals Ltd.
2015 Phase 1 NCT02750332 South Africa;
Sutphin Drugs
2019 - NCT04113772 India;
Swedish Orphan Biovitrum
2014 Phase 3 NCT02323529 Belgium;Denmark;France;Germany;Sweden;
2013 - NCT02320084 Austria;Belgium;Croatia;Czech Republic;Czechia;Denmark;Finland;France;Germany;Greece;Hungary;Ireland;Italy;Kosovo;Lithuania;Macedonia, The Former Yugoslav Republic of;Netherlands;Norway;Poland;Portugal;Romania;Slovakia;Spain;Sweden;Switzerland;United Kingdom;
2012 Phase 1 NCT01734889 France;Germany;United Kingdom;
Swedish Orphan Biovitrum AB
2012 - EUCTR2012-002286-36-DE Germany;United Kingdom;
Nitisinone 10 mg Tablet High Compritol
Cycle Pharmaceuticals Ltd.
2015 Phase 1 NCT02750709 South Africa;
Nitisinone Baked Tablet
Cycle Pharmaceuticals Ltd.
2016 Phase 1 NCT02750345 South Africa;
Orfadin
Cycle Pharmaceuticals Ltd.
2016 Phase 1 NCT02750345 South Africa;
2015 Phase 1 NCT02750709 South Africa;
Sutphin Drugs
2019 - NCT04113772 India;
Swedish Orphan Biovitrum AB (Publ)
2014 Phase 4 EUCTR2013-004132-29-BE Belgium;Denmark;Sweden;
2014 - EUCTR2013-004132-29-SE Belgium;Denmark;Sweden;
2014 - EUCTR2013-004132-29-DK Belgium;Denmark;Sweden;
Orfadin oral suspension 4mg/ml
Swedish Orphan Biovitrum AB
2012 - EUCTR2012-002286-36-GB Germany;United Kingdom;
2012 - EUCTR2012-002286-36-DE Germany;United Kingdom;
National Center for Research Resources (NCRR)
1994 Phase 2 NCT00004333 -
University of Washington
1998 - NCT00004443 Canada;United States;
Nitisinone
Cycle Pharmaceuticals Ltd.
2015 Phase 1 NCT02750332 South Africa;
Sutphin Drugs
2019 - NCT04113772 India;
Swedish Orphan Biovitrum
2014 Phase 3 NCT02323529 Belgium;Denmark;France;Germany;Sweden;
2013 - NCT02320084 Austria;Belgium;Croatia;Czech Republic;Czechia;Denmark;Finland;France;Germany;Greece;Hungary;Ireland;Italy;Kosovo;Lithuania;Macedonia, The Former Yugoslav Republic of;Netherlands;Norway;Poland;Portugal;Romania;Slovakia;Spain;Sweden;Switzerland;United Kingdom;
2012 Phase 1 NCT01734889 France;Germany;United Kingdom;
Swedish Orphan Biovitrum AB
2012 - EUCTR2012-002286-36-DE Germany;United Kingdom;
Nitisinone 10 mg Tablet High Compritol
Cycle Pharmaceuticals Ltd.
2015 Phase 1 NCT02750709 South Africa;
Nitisinone Baked Tablet
Cycle Pharmaceuticals Ltd.
2016 Phase 1 NCT02750345 South Africa;
Orfadin
Cycle Pharmaceuticals Ltd.
2016 Phase 1 NCT02750345 South Africa;
2015 Phase 1 NCT02750709 South Africa;
Sutphin Drugs
2019 - NCT04113772 India;
Swedish Orphan Biovitrum AB (Publ)
2014 Phase 4 EUCTR2013-004132-29-BE Belgium;Denmark;Sweden;
2014 - EUCTR2013-004132-29-SE Belgium;Denmark;Sweden;
2014 - EUCTR2013-004132-29-DK Belgium;Denmark;Sweden;
Orfadin oral suspension 4mg/ml
Swedish Orphan Biovitrum AB
2012 - EUCTR2012-002286-36-GB Germany;United Kingdom;
2012 - EUCTR2012-002286-36-DE Germany;United Kingdom;