278. Huge lymphatic malformation with cervicofacial lesion Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 19 / Drugs : 22 - (DrugBank : 7) / Drug target genes : 5 - Drug target pathways : 63
Drugs and their primary sponsors and trial info
Bleomycin
Fujino Akihiro
2016 - JPRN-jRCTs031180265 Japan;
CERC-006
Cerecor Inc
2021 Phase 1 NCT04994002 United States;
Indocyanine green
Aitaro Takimoto
2017 Phase 2 JPRN-jRCTs041190036 Japan;
Nagoya University Graduate School ofMedicine
2017 - JPRN-UMIN000025845 Japan;
L04AA10
CHRU TOURS
2019 Phase 2 EUCTR2019-001530-33-FR France;
MRI
University Hospital, Lille
2018 Phase 2 NCT03243019 France;
OK432
Richard JH Smith
1998 Phase 4 NCT03427619 United States;
Oral sirolimus
Children's Hospital of Fudan University
2021 Phase 4 NCT04921722 China;
PTX-022
Palvella Therapeutics, Inc.
2021 Phase 2 NCT05050149 United States;
Percutaneous sirolimus
Children's Hospital of Fudan University
2021 Phase 4 NCT04921722 China;
Picibanil
University of Iowa
2000 Phase 2/Phase 3 NCT00010452 United States;
Propranolol
University of Tokyo
2012 Phase 2 JPRN-UMIN000008498 Japan;
Rapamycin dosage
University Hospital, Lille
2018 Phase 2 NCT03243019 France;
Selenium
Medical College of Wisconsin
2010 Phase 1 NCT01212965 United States;
Sildenafil
Beijing Children's Hospital
2014 - ChiCTR-OPC-16008702 China;
Sildenafil 20 mg tablets
Stanford University
2015 Phase 2 NCT02335242 United States;
Sirolimus
Children's Hospital Medical Center, Cincinnati
2009 Phase 2 NCT00975819 United States;
Gifu University
2017 - JPRN-UMIN000030522 Japan;
Gifu University Hospital
2020 Phase 3 JPRN-UMIN000038973 Japan;
Medical University of South Carolina
2021 Phase 2 NCT04861064 United States;
Sirolimus 0, crème
CHRU TOURS
2019 Phase 2 EUCTR2018-001359-11-FR France;
Sirolimus 1mg/mL
CHRU TOURS
2019 Phase 2 EUCTR2019-001530-33-FR France;
Sirolimus Oral Liquid Product 1mg/mL
University Hospital, Tours
2020 Phase 2 NCT04128722 France;
Topical Sirolimus
University Hospital, Tours
2019 Phase 2 NCT03972592 France;
Topical Vehicle
University Hospital, Tours
2019 Phase 2 NCT03972592 France;
VT30
Venthera, Inc., a BridgeBio company
2020 Phase 1/Phase 2 NCT04409145 United States;
Water
Fujino Akihiro
2016 - JPRN-jRCTs031180265 Japan;
Fujino Akihiro
2016 - JPRN-jRCTs031180265 Japan;
CERC-006
Cerecor Inc
2021 Phase 1 NCT04994002 United States;
Indocyanine green
Aitaro Takimoto
2017 Phase 2 JPRN-jRCTs041190036 Japan;
Nagoya University Graduate School ofMedicine
2017 - JPRN-UMIN000025845 Japan;
L04AA10
CHRU TOURS
2019 Phase 2 EUCTR2019-001530-33-FR France;
MRI
University Hospital, Lille
2018 Phase 2 NCT03243019 France;
OK432
Richard JH Smith
1998 Phase 4 NCT03427619 United States;
Oral sirolimus
Children's Hospital of Fudan University
2021 Phase 4 NCT04921722 China;
PTX-022
Palvella Therapeutics, Inc.
2021 Phase 2 NCT05050149 United States;
Percutaneous sirolimus
Children's Hospital of Fudan University
2021 Phase 4 NCT04921722 China;
Picibanil
University of Iowa
2000 Phase 2/Phase 3 NCT00010452 United States;
Propranolol
University of Tokyo
2012 Phase 2 JPRN-UMIN000008498 Japan;
Rapamycin dosage
University Hospital, Lille
2018 Phase 2 NCT03243019 France;
Selenium
Medical College of Wisconsin
2010 Phase 1 NCT01212965 United States;
Sildenafil
Beijing Children's Hospital
2014 - ChiCTR-OPC-16008702 China;
Sildenafil 20 mg tablets
Stanford University
2015 Phase 2 NCT02335242 United States;
Sirolimus
Children's Hospital Medical Center, Cincinnati
2009 Phase 2 NCT00975819 United States;
Gifu University
2017 - JPRN-UMIN000030522 Japan;
Gifu University Hospital
2020 Phase 3 JPRN-UMIN000038973 Japan;
Medical University of South Carolina
2021 Phase 2 NCT04861064 United States;
Sirolimus 0, crème
CHRU TOURS
2019 Phase 2 EUCTR2018-001359-11-FR France;
Sirolimus 1mg/mL
CHRU TOURS
2019 Phase 2 EUCTR2019-001530-33-FR France;
Sirolimus Oral Liquid Product 1mg/mL
University Hospital, Tours
2020 Phase 2 NCT04128722 France;
Topical Sirolimus
University Hospital, Tours
2019 Phase 2 NCT03972592 France;
Topical Vehicle
University Hospital, Tours
2019 Phase 2 NCT03972592 France;
VT30
Venthera, Inc., a BridgeBio company
2020 Phase 1/Phase 2 NCT04409145 United States;
Water
Fujino Akihiro
2016 - JPRN-jRCTs031180265 Japan;