DR info

Clinical trials : 267 / Drugs : 241 - (DrugBank : 77) / Drug target genes : 68 - Drug target pathways : 180

Systemic amyloidosis and other diseases between which drug repositioning might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Drug repositionability

ID	Diseases (Sorted by drug repositionability)
28	Systemic amyloidosis
46	Malignant rheumatoid arthritis
51	Scleroderma
85	Idiopathic interstitial pneumonia
34	Neurofibromatosis
2	Amyotrophic lateral sclerosis
13	Multiple sclerosis/Neuromyelitis optica
49	Systemic lupus erythematosus
56	Behcet disease
26	HTLV-1-associated myelopathy
42	Polyarteritis nodosa
65	Primary immunodeficiency
96	Crohn disease
6	Parkinson disease
38	Stevens-Johnson syndrome
11	Myasthenia gravis
228	Bronchiolitis obliterans
331	Idiopathic multicentric castleman disease
127	Frontotemporal lobar degeneration
86	Pulmonary arterial hypertension
93	Primary biliary cholangitis
60	Aplastic anemia
266	Familial mediterranean fever
113	Muscular dystrophy
58	Hypertrophic cardiomyopathy
107	Juvenile idiopathic arthritis
227	Osler disease
53	Sjogren syndrome
61	Autoimmune hemolytic anemia
210	Single Ventricle
164	Oculocutaneous albinism
283	Acquired pure red cell aplasia
97	Ulcerative colitis
285	Fanconi anemia
36	Epidermolysis bullosa
226	Interstitial cystitis with Hunners ulcer
162	Pemphigoid
41	Giant cell arteritis
62	Paroxysmal nocturnal hemoglobinuria
284	Diamond-Blackfan anemia
35	Pemphigus
45	Eosinophilic granulomatosis with Polyangiitis
39	Toxic epidermal necrolysis
151	Rasmussen encephalitis
234	Peroxisomal disease (except Adrenoleukodystrophy)
20	Adrenoleukodystrophy
19	Lysosomal storage disease
16	Crow-Fukase syndrome
302	Leber hereditary optic neuropathy
95	Autoimmune hepatitis
222	Primary nephrotic syndrome
224	Purpura nephritis
66	IgA nephropathy
286	Hereditary sideroblastic anemia
50	Dermatomyositis
84	Sarcoidosis
168	Ehlers-Danlos syndrome
8	Huntington disease
40	Takayasu arteritis
70	Spinal stenosis
89	Lymphangioleiomyomatosis
300	IgG4-related disease
269	Pyogenic arthritis
256	Muscle glycogenosis
64	Thrombotic thrombocytopenic purpura
326	Osteopetrosis
299	Cystic fibrosis
55	Relapsing polychondritis
298	Hereditary pancreatitis
57	Idiopathic dilated cardiomyopathy
63	Idiopathic thrombocytopenic purpura
1	Spinal and bulbar muscular atrophy
158	Tuberous sclerosis
10	Charcot-Marie-Tooth disease
25	Progressive multifocal leukoencephalopathy
160	Congenital ichthyosis
14	Chronic inflammatory demyelinating polyneuropathy
87	Pulmonary veno-occlusive disease
274	Osteogenesis Imperfecta
169	Menkes disease
170	Occipital horn syndrome
67	Polycystic kidney disease
114	Non-dystrophic myotonia syndrome
288	Autoimmune acquired coagulation factor deficiency
15	Inclusion body myositis
193	Prader-Willi syndrome
94	Primary sclerosing cholangitis
231	Alpha-1-antitrypsin deficiency
43	Microscopic polyangiitis
280	Huge arteriovenous malformation with cervicofacial or limb lesion
90	Retinitis pigmentosa
144	Lennox-Gastaut syndrome
118	Myelomeningocele
22	Moyamoya disease
5	Progressive supranuclear palsy
106	Cryopyrin-associated periodic syndrome
251	Urea cycle disorder
235	Hypoparathyroidism
220	Rapidly progressive glomerulonephritis
30	Distal myopathy