283. Acquired pure red cell aplasia Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 19 / Drugs : 36 - (DrugBank : 23) / Drug target genes : 20 - Drug target pathways : 102
Drugs and their primary sponsors and trial info
AF37702 Injection
Takeda Development Centre Europe Ltd
2006 Phase 2 EUCTR2005-004944-30-GB Germany;United Kingdom;
2006 Phase 2 EUCTR2005-004944-30-DE Germany;United Kingdom;
AF37702, Hematide
Takeda Development Centre Europe Ltd
2006 Phase 2 EUCTR2005-004944-30-GB Germany;United Kingdom;
2006 Phase 2 EUCTR2005-004944-30-DE Germany;United Kingdom;
Alemtuzumab
University of Calgary
2017 Phase 2 NCT03214354 Canada;
Allogeneic Bone Marrow Transplantation
Fred Hutchinson Cancer Research Center
2022 Phase 2 NCT04965597 United States;
Anti-thymocyte globulin
Fairview University Medical Center
2000 - NCT00006055 United States;
Autologous Peripheral Blood Stem Cell Transplantation
Fairview University Medical Center
2000 - NCT00006055 United States;
Bortezomib/dexamethasone
Institute of Hematology & Blood Diseases Hospital
2020 Phase 2 NCT04423367 China;
Campath, Chemo and/or TBI Allo SCT
David Rizzieri, MD
1999 Phase 2 NCT00004143 United States;
Cyclophosphamide
Fairview University Medical Center
2000 - NCT00006055 United States;
Roswell Park Cancer Institute
2017 Phase 2 NCT03333486 United States;
Cyclophosphamide + pred
Chulalongkorn University
2009 Phase 3 NCT01288131 Thailand;
Cyclosporine
Fairview University Medical Center
2000 - NCT00006055 United States;
Cyclosporine A
Bing Han
2020 Phase 4 NCT04470804 China;
Cyclosporine combine with mycophenolate mofetil
Chulalongkorn University
2009 Phase 3 NCT01288131 Thailand;
Daclizumab
Neal Young, M.D.
1999 Phase 2 NCT00001962 United States;
Filgrastim
Fairview University Medical Center
2000 - NCT00006055 United States;
Fludarabine Phosphate
Fred Hutchinson Cancer Research Center
2022 Phase 2 NCT04965597 United States;
Roswell Park Cancer Institute
2017 Phase 2 NCT03333486 United States;
Hematide, peginesatide
Takeda Development Centre Europe Ltd
2006 Phase 2 EUCTR2005-004944-30-GB Germany;United Kingdom;
2006 Phase 2 EUCTR2005-004944-30-DE Germany;United Kingdom;
Leucine
Northwell Health
2013 Phase 1/Phase 2 NCT01362595 United States;
Methotrexate
Fred Hutchinson Cancer Research Center
2022 Phase 2 NCT04965597 United States;
Methylprednisolone
Fairview University Medical Center
2000 - NCT00006055 United States;
Peginesatide
Takeda
2006 Phase 2 NCT00314795 France;Germany;United Kingdom;
Peripheral Blood Stem Cell Transplantation
Fred Hutchinson Cancer Research Center
2022 Phase 2 NCT04965597 United States;
Roswell Park Cancer Institute
2017 Phase 2 NCT03333486 United States;
Prednisone
Fairview University Medical Center
2000 - NCT00006055 United States;
Rituximab
National Heart, Lung, and Blood Institute (NHLBI)
2005 Phase 2 NCT00229619 United States;
Sirolimus
Bing Han
2020 Phase 4 NCT04470804 China;
2018 Phase 4 NCT03364764 China;
University of Calgary
2017 Phase 2 NCT03214354 Canada;
Tacrolimus
Fred Hutchinson Cancer Research Center
2022 Phase 2 NCT04965597 United States;
Peking Union Medical College Hospital
2019 Phase 4 NCT03918265 China;
2018 Phase 4 NCT03540472 China;
Treosulfan
Fred Hutchinson Cancer Research Center
2022 Phase 2 NCT04965597 United States;
Trifluoperazine
Adrianna Vlachos
2019 Phase 1/Phase 2 NCT03966053 United States;
Takeda Development Centre Europe Ltd
2006 Phase 2 EUCTR2005-004944-30-GB Germany;United Kingdom;
2006 Phase 2 EUCTR2005-004944-30-DE Germany;United Kingdom;
AF37702, Hematide
Takeda Development Centre Europe Ltd
2006 Phase 2 EUCTR2005-004944-30-GB Germany;United Kingdom;
2006 Phase 2 EUCTR2005-004944-30-DE Germany;United Kingdom;
Alemtuzumab
University of Calgary
2017 Phase 2 NCT03214354 Canada;
Allogeneic Bone Marrow Transplantation
Fred Hutchinson Cancer Research Center
2022 Phase 2 NCT04965597 United States;
Anti-thymocyte globulin
Fairview University Medical Center
2000 - NCT00006055 United States;
Autologous Peripheral Blood Stem Cell Transplantation
Fairview University Medical Center
2000 - NCT00006055 United States;
Bortezomib/dexamethasone
Institute of Hematology & Blood Diseases Hospital
2020 Phase 2 NCT04423367 China;
Campath, Chemo and/or TBI Allo SCT
David Rizzieri, MD
1999 Phase 2 NCT00004143 United States;
Cyclophosphamide
Fairview University Medical Center
2000 - NCT00006055 United States;
Roswell Park Cancer Institute
2017 Phase 2 NCT03333486 United States;
Cyclophosphamide + pred
Chulalongkorn University
2009 Phase 3 NCT01288131 Thailand;
Cyclosporine
Fairview University Medical Center
2000 - NCT00006055 United States;
Cyclosporine A
Bing Han
2020 Phase 4 NCT04470804 China;
Cyclosporine combine with mycophenolate mofetil
Chulalongkorn University
2009 Phase 3 NCT01288131 Thailand;
Daclizumab
Neal Young, M.D.
1999 Phase 2 NCT00001962 United States;
Filgrastim
Fairview University Medical Center
2000 - NCT00006055 United States;
Fludarabine Phosphate
Fred Hutchinson Cancer Research Center
2022 Phase 2 NCT04965597 United States;
Roswell Park Cancer Institute
2017 Phase 2 NCT03333486 United States;
Hematide, peginesatide
Takeda Development Centre Europe Ltd
2006 Phase 2 EUCTR2005-004944-30-GB Germany;United Kingdom;
2006 Phase 2 EUCTR2005-004944-30-DE Germany;United Kingdom;
Leucine
Northwell Health
2013 Phase 1/Phase 2 NCT01362595 United States;
Methotrexate
Fred Hutchinson Cancer Research Center
2022 Phase 2 NCT04965597 United States;
Methylprednisolone
Fairview University Medical Center
2000 - NCT00006055 United States;
Peginesatide
Takeda
2006 Phase 2 NCT00314795 France;Germany;United Kingdom;
Peripheral Blood Stem Cell Transplantation
Fred Hutchinson Cancer Research Center
2022 Phase 2 NCT04965597 United States;
Roswell Park Cancer Institute
2017 Phase 2 NCT03333486 United States;
Prednisone
Fairview University Medical Center
2000 - NCT00006055 United States;
Rituximab
National Heart, Lung, and Blood Institute (NHLBI)
2005 Phase 2 NCT00229619 United States;
Sirolimus
Bing Han
2020 Phase 4 NCT04470804 China;
2018 Phase 4 NCT03364764 China;
University of Calgary
2017 Phase 2 NCT03214354 Canada;
Tacrolimus
Fred Hutchinson Cancer Research Center
2022 Phase 2 NCT04965597 United States;
Peking Union Medical College Hospital
2019 Phase 4 NCT03918265 China;
2018 Phase 4 NCT03540472 China;
Treosulfan
Fred Hutchinson Cancer Research Center
2022 Phase 2 NCT04965597 United States;
Trifluoperazine
Adrianna Vlachos
2019 Phase 1/Phase 2 NCT03966053 United States;