DR info

Clinical trials : 71 / Drugs : 70 - (DrugBank : 39) / Drug target genes : 35 - Drug target pathways : 60

Drugs and their primary sponsors and trial info

A4250
   ALBIREO AB
      2020   Phase 3   EUCTR2019-003807-37-IT   Australia;Belgium;Canada;China;Denmark;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Poland;Spain;Taiwan;Turkey;United Kingdom;United States;
   Albireo AB
      2020   Phase 3   EUCTR2019-003807-37-NL   Australia;Belgium;Canada;China;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Poland;Spain;Taiwan;Turkey;United Kingdom;United States;
      2020   Phase 3   EUCTR2019-003807-37-HU   Australia;Belgium;Canada;China;Denmark;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Poland;Spain;Taiwan;Turkey;United Kingdom;United States;
      2020   Phase 3   EUCTR2019-003807-37-GB   Australia;Belgium;Canada;China;Denmark;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Poland;Spain;Taiwan;Turkey;United Kingdom;United States;
      2020   Phase 3   EUCTR2019-003807-37-FR   Australia;Belgium;Canada;China;Denmark;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Poland;Spain;Taiwan;Turkey;United Kingdom;United States;
      -   Phase 3   EUCTR2019-003807-37-PL   Australia;Belgium;Canada;China;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Poland;Spain;Taiwan;Turkey;United Kingdom;United States;
      -   Phase 3   EUCTR2019-003807-37-DE   Australia;Belgium;Canada;China;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Poland;Spain;Taiwan;Turkey;United Kingdom;United States;
      -   Phase 3   EUCTR2019-003807-37-BE   Australia;Belgium;Canada;China;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Poland;Spain;Taiwan;Turkey;United Kingdom;United States;
Acetylcysteine
   Guangzhou Women and Children Medical Center
      2020   Phase 4   ChiCTR2000040505   China;
Ammonia
   Children's Hospital Affiliated to Zhejiang University Medical College
      2021   -   ChiCTR2100044533   China;
Belimumab
   Guangzhou Women and Children Medical Center
      2021   Phase 4   ChiCTR2100046985   China;
Bezafibrate
   Terui Keita
      2021   Phase 2   JPRN-jRCTs031210066   Japan;
Bicarbonate Ringer's solution
   Tongji Hospital
      2020   -   NCT04506021   -
Cefoperazone
   Children's Hospital of Fudan University
      2016   -   ChiCTR-IPR-16008609   China;
Combination Product: high MCT formula
   Children's Hospital of Fudan University
      2021   -   NCT05072626   China;
Corticosteroids
   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
      2005   -   NCT00294684   United States;
Desflurane anesthetics
   Yonsei University
      2011   -   NCT01443572   Korea, Republic of;
Dexamethasone
   The First Affiliated Hospital of Sun Yat Sen University
      2007   -   ChiCTR-TNRC-09000331   China;
Dimethyl fumarate
   Children's Hospital of Fudan University
      2020   Phase 4   ChiCTR2000035667   China;
Eicosapentaenoic acid
   Sumida Wataru
      2016   -   JPRN-jRCTs041180088   Japan;
Epadel
   Nagoya University
      2016   -   JPRN-UMIN000024625   Japan;
Filgrastim
   Holterman, Ai-Xuan, M.D.
      2020   Phase 2   NCT04373941   Pakistan;Vietnam;
Gold
   Children's Hospital Affiliated to Zhejiang University Medical College
      2021   -   ChiCTR2100044533   China;
   Children's Hospital of Fudan University
      2020   Phase 0   ChiCTR2000032983   China;
      2019   -   ChiCTR1800019866   China;
      2014   Phase 1 study   ChiCTR-DPD-15005847   China;
   Department of Medical Ultrasonics, the First Affiliated Hospital of Sun Yat-sen University
      2018   -   ChiCTR1800017428   China;
   Department of Pediatric Surgery, Union Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology
      2020   Phase 0   ChiCTR2000034127   China;
Granulocyte Colony-Stimulating Factor
   Holterman, Ai-Xuan, M.D.
      2018   Early Phase 1   NCT03395028   United States;Vietnam;
ICG Pulsion
   University Medical Centre Groningen
      2010   -   EUCTR2009-014886-21-NL   Netherlands;
ICG-Pulsion
   University Medical Centre Groningen
      2010   -   EUCTR2009-014886-21-NL   Netherlands;
Indocyanine green
   Juntendo University School of Medicine
      2017   Phase 2   JPRN-UMIN000027972   Japan;
   Nagoya University Graduate School of Medicine
      2017   -   JPRN-UMIN000028549   Japan;
Intravenous immunoglobulin (IVIG)
   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
      2013   Phase 1/Phase 2   NCT01854827   Canada;United States;
Lactated Ringer
   RenJi Hospital
      2018   -   NCT03563378   China;
Lactobacillus casei rhamnosus (Lcr35)
   National Taiwan University Hospital
      2003   -   NCT00166868   Taiwan;
MARALIXIBAT CHLORIDE
   Mirum Pharmaceuticals Inc.
      2021   Phase 2   EUCTR2020-000974-22-IT   Canada;France;Germany;Italy;Poland;United Kingdom;United States;
      2020   Phase 2   EUCTR2020-000974-22-FR   Canada;France;Germany;Italy;Poland;United Kingdom;United States;
      -   Phase 2   EUCTR2020-000974-22-PL   Canada;France;Germany;Italy;Poland;United Kingdom;United States;
      -   Phase 2   EUCTR2020-000974-22-GB   Canada;France;Germany;Italy;Poland;United Kingdom;United States;
      -   Phase 2   EUCTR2019-002755-42-PL   Australia;Belgium;Canada;France;Poland;Spain;United Kingdom;United States;
      -   Phase 2   EUCTR2019-002755-42-BE   Australia;Belgium;Canada;France;Poland;Spain;United Kingdom;United States;
MCT powder
   Children's Hospital of Fudan University
      2021   -   NCT05072626   China;
Magnesium gluconate
   National Center for Research Resources (NCRR)
      2000   -   NCT00007033   United States;
Magnesium sulfate
   National Center for Research Resources (NCRR)
      2000   -   NCT00007033   United States;
Maralixibat
   Mirum Pharmaceuticals, Inc.
      2021   Phase 2   NCT04524390   Germany;Poland;United Kingdom;United States;
Maralixibat (formely SHP625 or LUM001)
   Mirum Pharmaceuticals Inc.
      -   Phase 2   EUCTR2019-002755-42-PL   Australia;Belgium;Canada;France;Poland;Spain;United Kingdom;United States;
      -   Phase 2   EUCTR2019-002755-42-BE   Australia;Belgium;Canada;France;Poland;Spain;United Kingdom;United States;
Maralixibat cloruro
   Mirum Pharmaceuticals Inc.
      2021   Phase 2   EUCTR2020-000974-22-IT   Canada;France;Germany;Italy;Poland;United Kingdom;United States;
Meloxicam
   Yonsei University
      2009   Phase 4   NCT02298218   -
Methylprednisolone
   The First Affiliated Hospital of Sun Yat Sen University
      2007   -   ChiCTR-TNRC-09000331   China;
N-Acetyl cysteine
   Baylor College of Medicine
      2018   Phase 2   NCT03499249   United States;
Neomycin
   National Taiwan University Hospital
      2003   -   NCT00166868   Taiwan;
Normal saline
   RenJi Hospital
      2018   -   NCT03563378   China;
OCA
   Intercept Pharmaceuticals, Inc.
      2018   Phase 2   EUCTR2014-004693-42-FI   Belgium;Finland;Germany;Italy;Netherlands;United Kingdom;United States;
      2016   -   EUCTR2014-004693-42-NL   Canada;Germany;Netherlands;United Kingdom;United States;
      2015   Phase 2   EUCTR2014-004693-42-GB   Belgium;Finland;Germany;Italy;Netherlands;United Kingdom;United States;
      2015   Phase 2   EUCTR2014-004693-42-DE   Belgium;Finland;Germany;Italy;Netherlands;United Kingdom;United States;
      2015   Phase 2   EUCTR2014-004693-42-BE   Belgium;Finland;France;Germany;Netherlands;Poland;United Kingdom;
Obeticholic acid
   Intercept Pharmaceuticals, Inc.
      2016   -   EUCTR2014-004693-42-NL   Canada;Germany;Netherlands;United Kingdom;United States;
Ocaliva
   Intercept Pharmaceuticals, Inc.
      2018   Phase 2   EUCTR2014-004693-42-FI   Belgium;Finland;Germany;Italy;Netherlands;United Kingdom;United States;
      2015   Phase 2   EUCTR2014-004693-42-GB   Belgium;Finland;Germany;Italy;Netherlands;United Kingdom;United States;
      2015   Phase 2   EUCTR2014-004693-42-DE   Belgium;Finland;Germany;Italy;Netherlands;United Kingdom;United States;
      2015   Phase 2   EUCTR2014-004693-42-BE   Belgium;Finland;France;Germany;Netherlands;Poland;United Kingdom;
Odevixibat
   ALBIREO AB
      2020   Phase 3   EUCTR2019-003807-37-IT   Australia;Belgium;Canada;China;Denmark;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Poland;Spain;Taiwan;Turkey;United Kingdom;United States;
   Albireo
      2020   Phase 3   NCT04336722   Australia;Belgium;Canada;China;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Poland;Spain;Taiwan;Turkey;United Kingdom;United States;
   Albireo AB
      2020   Phase 3   EUCTR2019-003807-37-NL   Australia;Belgium;Canada;China;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Poland;Spain;Taiwan;Turkey;United Kingdom;United States;
      2020   Phase 3   EUCTR2019-003807-37-HU   Australia;Belgium;Canada;China;Denmark;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Poland;Spain;Taiwan;Turkey;United Kingdom;United States;
      2020   Phase 3   EUCTR2019-003807-37-GB   Australia;Belgium;Canada;China;Denmark;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Poland;Spain;Taiwan;Turkey;United Kingdom;United States;
      2020   Phase 3   EUCTR2019-003807-37-FR   Australia;Belgium;Canada;China;Denmark;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Poland;Spain;Taiwan;Turkey;United Kingdom;United States;
      -   Phase 3   EUCTR2019-003807-37-PL   Australia;Belgium;Canada;China;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Poland;Spain;Taiwan;Turkey;United Kingdom;United States;
      -   Phase 3   EUCTR2019-003807-37-DE   Australia;Belgium;Canada;China;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Poland;Spain;Taiwan;Turkey;United Kingdom;United States;
      -   Phase 3   EUCTR2019-003807-37-BE   Australia;Belgium;Canada;China;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Poland;Spain;Taiwan;Turkey;United Kingdom;United States;
Oral Vancomycin
   Sacramento Pediatric Gastroenterology
      2010   Phase 1   NCT02137668   United States;
Other Crystalloid
   Tongji Hospital
      2020   -   NCT04506021   -
Pentoxifylline
   Baylor College of Medicine
      2013   Phase 2   NCT01774487   United States;
Prednisolone
   King's College Hospital NHS Trust
      2000   Phase 3   NCT00539565   United Kingdom;
Propanolol
   Institute of Liver and Biliary Sciences, India
      2020   -   NCT04494763   India;
Propofol
   Tianjin First Center Hospital
      2018   -   ChiCTR1800015778   China;
   Tianjin First Central Hospital
      2018   -   ChiCTR-IOR-17013585   China;
Rifaximin
   Tianjin First Center Hospital
      2019   Phase 0   ChiCTR1900023843   China;
Rituximab
   Guangzhou Women and Children Medical Center
      2020   Phase 4   ChiCTR2000031738   China;
Rocuronium
   Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University
      2016   -   ChiCTR-OOC-16008707   China;
Sevoflurane
   Children's Hospital of Fudan University
      2012   -   NCT02471209   -
   Tianjin First Central Hospital
      2018   -   ChiCTR-IOR-17013585   China;
Sevoflurane anesthetics
   Yonsei University
      2011   -   NCT01443572   Korea, Republic of;
UDCA
   Children's Hospital of Fudan University
      2018   -   ChiCTR1800015250   China;
Umbilical Cord Derived Mesenchymal Stem Cell (UC -MSC) Transplantation
   Vinmec Research Institute of Stem Cell and Gene Technology
      2019   Phase 1/Phase 2   NCT04522869   Vietnam;
VO4CX
   University Medical Centre Groningen
      2010   -   EUCTR2009-014886-21-NL   Netherlands;
Vancomycin
   Stanford University
      2007   Phase 1   NCT01322386   -