DR info

Clinical trials : 1,695 / Drugs : 1,527 - (DrugBank : 268) / Drug target genes : 111 - Drug target pathways : 174

Cystic fibrosis and other diseases between which drug repositioning might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Drug repositionability

ID	Diseases (Sorted by drug repositionability)
299	Cystic fibrosis
13	Multiple sclerosis/Neuromyelitis optica
46	Malignant rheumatoid arthritis
6	Parkinson disease
226	Interstitial cystitis with Hunners ulcer
2	Amyotrophic lateral sclerosis
63	Idiopathic thrombocytopenic purpura
96	Crohn disease
97	Ulcerative colitis
236	Pseudohypoparathyroidism
86	Pulmonary arterial hypertension
65	Primary immunodeficiency
246	Methylmalonic acidemia
265	Lipodystrophy
78	Hypopituitarism
49	Systemic lupus erythematosus
51	Scleroderma
113	Muscular dystrophy
107	Juvenile idiopathic arthritis
21	Mitochondrial disease
225	Congenital nephrogenic diabetes insipidus
50	Dermatomyositis
19	Lysosomal storage disease
8	Huntington disease
53	Sjogren syndrome
20	Adrenoleukodystrophy
162	Pemphigoid
224	Purpura nephritis
271	Ankylosing spondylitis
56	Behcet disease
58	Hypertrophic cardiomyopathy
90	Retinitis pigmentosa
164	Oculocutaneous albinism
39	Toxic epidermal necrolysis
158	Tuberous sclerosis
95	Autoimmune hepatitis
285	Fanconi anemia
74	Prolactin secreting pituitary adenoma
64	Thrombotic thrombocytopenic purpura
75	Cushing disease
98	Eosinophilic gastrointestinal disease
84	Sarcoidosis
60	Aplastic anemia
66	IgA nephropathy
302	Leber hereditary optic neuropathy
294	Congenital diaphragmatic hernia
274	Osteogenesis Imperfecta
26	HTLV-1-associated myelopathy
210	Single Ventricle
41	Giant cell arteritis
62	Paroxysmal nocturnal hemoglobinuria
326	Osteopetrosis
93	Primary biliary cholangitis
85	Idiopathic interstitial pneumonia
151	Rasmussen encephalitis
222	Primary nephrotic syndrome
179	Williams syndrome
67	Polycystic kidney disease
227	Osler disease
160	Congenital ichthyosis
228	Bronchiolitis obliterans
17	Multiple system atrophy
5	Progressive supranuclear palsy
28	Systemic amyloidosis
298	Hereditary pancreatitis
206	Fragile X syndrome
286	Hereditary sideroblastic anemia
234	Peroxisomal disease (except Adrenoleukodystrophy)
156	Rett syndrome
283	Acquired pure red cell aplasia
45	Eosinophilic granulomatosis with Polyangiitis
11	Myasthenia gravis
301	Macular dystrophy
7	Corticobasal degeneration
36	Epidermolysis bullosa
76	Pituitary gonadotropin secretion hyperthyroidism
38	Stevens-Johnson syndrome
269	Pyogenic arthritis
284	Diamond-Blackfan anemia
296	Biliary atresia
251	Urea cycle disorder
309	Progressive myoclonus epilepsy
55	Relapsing polychondritis
94	Primary sclerosing cholangitis
254	Porphyria
77	Growth hormone secreting pituitary adenoma
337	Homocystinuria
195	Noonan syndrome
263	Cerebrotendinous xanthomatosis
282	Congenital dyserythropoietic anemia
120	Hereditary dystonia
70	Spinal stenosis
61	Autoimmune hemolytic anemia
40	Takayasu arteritis
42	Polyarteritis nodosa
127	Frontotemporal lobar degeneration
288	Autoimmune acquired coagulation factor deficiency
15	Inclusion body myositis
233	Wolfram syndrome
218	Alport syndrome
83	Addison disease
124	Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy
18	Spinocerebellar degeneration
4	Primary lateral sclerosis
140	Dorabe syndrome
37	Generalised pustular psoriasis
81	Congenital adrenal hyperplasia
187	Kabuki syndrome
171	Wilson disease
310	Congenital anomalies syndrome
229	Autoimmune pulmonary alveolar proteinosis
88	Chronic thromboembolic pulmonary hypertension
201	Angelman syndrome
168	Ehlers-Danlos syndrome
79	Homozygous familial hypercholesterolemia
256	Muscle glycogenosis
106	Cryopyrin-associated periodic syndrome
333	Hutchinson-Gilford syndrome
238	Vitamin D-resistant rickets
72	Pituitary ADH secretion disorder
235	Hypoparathyroidism
71	Idiopathic osteonecrosis of the femoral head
3	Spinal muscular atrophy
232	Carney complex
111	Congenital myopathy
317	Trifunctional protein deficiency
191	Werner syndrome
290	Chronic nonspecific multiple ulcers of the small intestine
220	Rapidly progressive glomerulonephritis
30	Distal myopathy