38. Stevens-Johnson syndrome Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 17 / Drugs : 29 - (DrugBank : 9) / Drug target genes : 15 - Drug target pathways : 101
Stevens-Johnson syndrome and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
ID | Diseases (Sorted by score) | Score |
---|---|---|
38 | Stevens-Johnson syndrome | - |
28 | Systemic amyloidosis | 13.265 |
51 | Scleroderma | 13.182 |
46 | Malignant rheumatoid arthritis | 13.137 |
13 | Multiple sclerosis/Neuromyelitis optica | 13.116 |
107 | Juvenile idiopathic arthritis | 11.700 |
53 | Sjogren syndrome | 11.676 |
96 | Crohn disease | 11.401 |
2 | Amyotrophic lateral sclerosis | 11.398 |
36 | Epidermolysis bullosa | 10.188 |
113 | Muscular dystrophy | 10.088 |
226 | Interstitial cystitis with Hunners ulcer | 10.050 |
97 | Ulcerative colitis | 9.801 |
6 | Parkinson disease | 9.753 |
58 | Hypertrophic cardiomyopathy | 8.739 |
39 | Toxic epidermal necrolysis | 8.345 |
85 | Idiopathic interstitial pneumonia | 7.003 |
285 | Fanconi anemia | 6.480 |
228 | Bronchiolitis obliterans | 6.382 |
60 | Aplastic anemia | 6.171 |
151 | Rasmussen encephalitis | 6.000 |
45 | Eosinophilic granulomatosis with Polyangiitis | 5.926 |
65 | Primary immunodeficiency | 5.760 |
284 | Diamond-Blackfan anemia | 5.624 |
40 | Takayasu arteritis | 5.461 |
42 | Polyarteritis nodosa | 5.415 |
41 | Giant cell arteritis | 5.172 |
164 | Oculocutaneous albinism | 5.145 |
56 | Behcet disease | 5.096 |
26 | HTLV-1-associated myelopathy | 5.053 |
269 | Pyogenic arthritis | 5.009 |
302 | Leber hereditary optic neuropathy | 5.000 |
50 | Dermatomyositis | 4.889 |
298 | Hereditary pancreatitis | 4.830 |
283 | Acquired pure red cell aplasia | 4.719 |
19 | Lysosomal storage disease | 4.700 |
95 | Autoimmune hepatitis | 4.642 |
49 | Systemic lupus erythematosus | 4.529 |
62 | Paroxysmal nocturnal hemoglobinuria | 4.511 |
227 | Osler disease | 4.403 |
55 | Relapsing polychondritis | 4.200 |
162 | Pemphigoid | 4.059 |
11 | Myasthenia gravis | 3.847 |
224 | Purpura nephritis | 3.840 |
286 | Hereditary sideroblastic anemia | 3.750 |
64 | Thrombotic thrombocytopenic purpura | 3.750 |
222 | Primary nephrotic syndrome | 3.695 |
160 | Congenital ichthyosis | 3.600 |
84 | Sarcoidosis | 3.585 |
34 | Neurofibromatosis | 3.567 |
168 | Ehlers-Danlos syndrome | 3.519 |
20 | Adrenoleukodystrophy | 3.382 |
1 | Spinal and bulbar muscular atrophy | 3.333 |
61 | Autoimmune hemolytic anemia | 3.264 |
10 | Charcot-Marie-Tooth disease | 3.182 |
256 | Muscle glycogenosis | 3.097 |
234 | Peroxisomal disease (except Adrenoleukodystrophy) | 3.056 |
66 | IgA nephropathy | 3.017 |
93 | Primary biliary cholangitis | 3.017 |
127 | Frontotemporal lobar degeneration | 2.940 |
63 | Idiopathic thrombocytopenic purpura | 2.880 |
274 | Osteogenesis Imperfecta | 2.857 |
90 | Retinitis pigmentosa | 2.841 |
70 | Spinal stenosis | 2.727 |
326 | Osteopetrosis | 2.708 |
299 | Cystic fibrosis | 2.625 |
86 | Pulmonary arterial hypertension | 2.616 |
114 | Non-dystrophic myotonia syndrome | 2.593 |
231 | Alpha-1-antitrypsin deficiency | 2.143 |
158 | Tuberous sclerosis | 2.143 |
16 | Crow-Fukase syndrome | 2.040 |
140 | Dorabe syndrome | 2.014 |
144 | Lennox-Gastaut syndrome | 2.007 |
193 | Prader-Willi syndrome | 1.993 |
156 | Rett syndrome | 1.883 |
8 | Huntington disease | 1.865 |
35 | Pemphigus | 1.600 |
220 | Rapidly progressive glomerulonephritis | 1.000 |
30 | Distal myopathy | 1.000 |