39. Toxic epidermal necrolysis Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 13 / Drugs : 19 - (DrugBank : 8) / Drug target genes : 11 - Drug target pathways : 103
Toxic epidermal necrolysis and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 39 | Toxic epidermal necrolysis | - |
| 53 | Sjogren syndrome | 9.256 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 9.125 |
| 38 | Stevens-Johnson syndrome | 8.345 |
| 228 | Bronchiolitis obliterans | 7.810 |
| 85 | Idiopathic interstitial pneumonia | 7.512 |
| 49 | Systemic lupus erythematosus | 7.493 |
| 2 | Amyotrophic lateral sclerosis | 7.449 |
| 160 | Congenital ichthyosis | 6.788 |
| 62 | Paroxysmal nocturnal hemoglobinuria | 6.649 |
| 285 | Fanconi anemia | 6.400 |
| 56 | Behcet disease | 6.303 |
| 26 | HTLV-1-associated myelopathy | 6.278 |
| 60 | Aplastic anemia | 6.234 |
| 63 | Idiopathic thrombocytopenic purpura | 6.206 |
| 50 | Dermatomyositis | 6.182 |
| 90 | Retinitis pigmentosa | 6.174 |
| 36 | Epidermolysis bullosa | 6.174 |
| 107 | Juvenile idiopathic arthritis | 6.154 |
| 28 | Systemic amyloidosis | 6.083 |
| 65 | Primary immunodeficiency | 6.012 |
| 151 | Rasmussen encephalitis | 6.000 |
| 299 | Cystic fibrosis | 6.000 |
| 51 | Scleroderma | 5.973 |
| 96 | Crohn disease | 5.922 |
| 46 | Malignant rheumatoid arthritis | 5.913 |
| 269 | Pyogenic arthritis | 5.642 |
| 45 | Eosinophilic granulomatosis with Polyangiitis | 5.444 |
| 95 | Autoimmune hepatitis | 5.392 |
| 284 | Diamond-Blackfan anemia | 5.264 |
| 227 | Osler disease | 5.229 |
| 40 | Takayasu arteritis | 5.167 |
| 42 | Polyarteritis nodosa | 5.140 |
| 302 | Leber hereditary optic neuropathy | 5.000 |
| 162 | Pemphigoid | 4.994 |
| 41 | Giant cell arteritis | 4.994 |
| 164 | Oculocutaneous albinism | 4.979 |
| 222 | Primary nephrotic syndrome | 4.747 |
| 226 | Interstitial cystitis with Hunners ulcer | 4.733 |
| 19 | Lysosomal storage disease | 4.713 |
| 55 | Relapsing polychondritis | 4.636 |
| 97 | Ulcerative colitis | 4.579 |
| 224 | Purpura nephritis | 4.364 |
| 64 | Thrombotic thrombocytopenic purpura | 4.295 |
| 283 | Acquired pure red cell aplasia | 4.182 |
| 20 | Adrenoleukodystrophy | 4.017 |
| 286 | Hereditary sideroblastic anemia | 3.977 |
| 61 | Autoimmune hemolytic anemia | 3.927 |
| 66 | IgA nephropathy | 3.740 |
| 93 | Primary biliary cholangitis | 3.740 |
| 11 | Myasthenia gravis | 3.636 |
| 58 | Hypertrophic cardiomyopathy | 3.614 |
| 113 | Muscular dystrophy | 3.550 |
| 234 | Peroxisomal disease (except Adrenoleukodystrophy) | 3.409 |
| 6 | Parkinson disease | 3.360 |
| 274 | Osteogenesis Imperfecta | 3.247 |
| 326 | Osteopetrosis | 3.125 |
| 158 | Tuberous sclerosis | 2.662 |
| 94 | Primary sclerosing cholangitis | 1.990 |
| 37 | Generalised pustular psoriasis | 1.145 |
| 35 | Pemphigus | 1.116 |
| 159 | Xeroderma pigmentosum | 1.018 |
| 16 | Crow-Fukase syndrome | 1.018 |
| 220 | Rapidly progressive glomerulonephritis | 1.000 |
| 30 | Distal myopathy | 1.000 |