41. Giant cell arteritis Disease details / Clinical trials / Drug dev / DR info


Clinical trials : 131 Drugs : 139 - (DrugBank : 36) / Drug target genes : 33 - Drug target pathways : 125

Drugs and their primary sponsors and trial info
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione   
   Southend Hospital
      2012   -   EUCTR2011-005090-22-GB   United Kingdom;
18F-FDG   
   Svendborg Hospital
      2017   -   NCT02985424   Denmark;
18F]PEG-Folate   
   University Medical Center Groningen, Department of Rheumatology and Clinical Immunology
      2021   Phase 2   EUCTR2020-001019-26-NL   Netherlands;
ABT-494   
   ABBVIE DEUTSCHLAND GMBH & CO. KG
      2019   Phase 3   EUCTR2017-003978-13-IT   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Italy;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
   AbbVie Deutschland GmbH & Co. KG
      2019   Phase 3   EUCTR2017-003978-13-RO   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Italy;Japan;Netherlands;New Zealand;Portugal;Romania;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-PT   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-NL   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-HU   Australia;Austria;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-GR   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-FR   Australia;Austria;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-ES   Australia;Austria;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-DK   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-DE   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Italy;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-BE   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Italy;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-AT   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
AIN457   
   NOVARTIS PHARMA AG
      2021   Phase 3   EUCTR2020-004809-31-IT   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Czechia;Denmark;Finland;France;Germany;Guatemala;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;South Africa;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
   Novartis Pharma AG
      2021   Phase 3   EUCTR2020-004809-31-PT   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Czechia;Denmark;Estonia;Finland;France;Germany;Guatemala;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;South Africa;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
      2021   Phase 3   EUCTR2020-004809-31-NO   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Czechia;Denmark;Estonia;Finland;France;Germany;Guatemala;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;South Africa;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
      2021   Phase 3   EUCTR2020-004809-31-FR   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Czechia;Denmark;Estonia;Finland;France;Germany;Guatemala;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;South Africa;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
   Novartis Pharma GmbH
      2018   Phase 2   EUCTR2018-002610-12-DE   Germany;
Abatacept   
   Bristol-Myers Squibb
      2017   Phase 3   NCT03192969   Australia;Austria;Belgium;Bulgaria;Canada;Denmark;Estonia;France;Germany;Greece;Ireland;Italy;Netherlands;Poland;Romania;Serbia;Spain;Sweden;Switzerland;United Kingdom;United States;
   National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
      2008   Phase 2   NCT00556439   Canada;United States;
   University of Pennsylvania
      2021   Phase 3   NCT04474847   United States;
Adalimumab   
   Assistance Publique - Hôpitaux de Paris
      2006   Phase 3   NCT00305539   France;
Alendronate versus alfacalcidol (1-alpha OH vitamin D)   
   UMC Utrecht
      2000   Phase 3   NCT00138983   Netherlands;
Anti-thymocyte globulin   
   Fairview University Medical Center
      2000   -   NCT00006055   United States;
Autologous Peripheral Blood Stem Cell Transplantation   
   Fairview University Medical Center
      2000   -   NCT00006055   United States;
BOSENTAN MYLAN   
   CHU de Nice
      2019   Phase 3   EUCTR2018-004072-35-FR   France;
Baricitinib   
   Matthew J Koster
      2017   Phase 2   NCT03026504   United States;
Blood samples   
   Centre Hospitalier Universitaire Dijon
      2020   Phase 3   NCT03892785   France;
      2019   Phase 2   NCT03711448   France;
      2017   -   NCT03313102   France;
      2015   -   NCT02857192   France;
CNTO 136   
   GLAXOSMITHKLINE RESEARCH AND DEVELOPMENT
      2016   Phase 3   EUCTR2015-001758-14-IT   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;Sweden;United Kingdom;United States;
   GlaxoSmithKline Research and Development Limited
      2016   Phase 3   EUCTR2015-001758-14-NL   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;Sweden;United Kingdom;United States;
      2016   Phase 3   EUCTR2015-001758-14-HU   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;Sweden;United Kingdom;United States;
      2016   Phase 3   EUCTR2015-001758-14-BG   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;Sweden;United Kingdom;United States;
      2015   Phase 3   EUCTR2015-001758-14-ES   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;Sweden;United Kingdom;United States;
      2015   Phase 3   EUCTR2015-001758-14-DE   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;United Kingdom;United States;
      2015   Phase 3   EUCTR2015-001758-14-BE   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;Sweden;United Kingdom;United States;
CNTO1959   
   JANSSEN CILAG INTERNATIONAL NV
      2020   Phase 2   EUCTR2020-000622-26-IT   Belgium;Canada;France;Germany;Italy;Poland;Spain;United States;
   Janssen-Cilag International N.V.
      2021   Phase 2   EUCTR2020-000622-26-DE   Belgium;Canada;France;Germany;Israel;Italy;Poland;Spain;United States;
Capsule di prednisone   
   GLAXOSMITHKLINE RESEARCH AND DEVELOPMENT
      2016   Phase 3   EUCTR2015-001758-14-IT   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;Sweden;United Kingdom;United States;
Combination Product: mavrilimumab   
   Kiniksa Pharmaceuticals, Ltd.
      2018   Phase 2   NCT03827018   Australia;Belgium;Croatia;Estonia;Germany;Ireland;Italy;Netherlands;New Zealand;Poland;Serbia;Slovenia;Spain;United Kingdom;United States;
Cortancyl ®   
   SANOFI-AVENTIS RECHERCHE E DEVELOPPEMENT
      2018   Phase 3   EUCTR2017-002988-18-IT   Argentina;Australia;Austria;Belgium;Canada;Chile;Croatia;Denmark;Estonia;Finland;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Russian Federation;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
   Sanofi-Aventis Recherche & Développement
      2019   Phase 3   EUCTR2017-002988-18-SI   Argentina;Australia;Austria;Belgium;Canada;Chile;Croatia;Denmark;Estonia;Finland;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Russian Federation;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
      2019   Phase 3   EUCTR2017-002988-18-PT   Argentina;Australia;Austria;Belgium;Canada;Chile;Croatia;Denmark;Estonia;Finland;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Russian Federation;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
      2019   Phase 3   EUCTR2017-002988-18-HR   Argentina;Australia;Austria;Belgium;Canada;Chile;Croatia;Denmark;Estonia;Finland;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Russian Federation;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
      2019   Phase 3   EUCTR2017-002988-18-GB   Argentina;Australia;Austria;Belgium;Canada;Chile;Croatia;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Russian Federation;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
      2019   Phase 3   EUCTR2017-002988-18-FR   Argentina;Australia;Austria;Belgium;Canada;Chile;Croatia;Denmark;Estonia;Finland;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Russian Federation;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
      2019   Phase 3   EUCTR2017-002988-18-FI   Argentina;Australia;Austria;Belgium;Canada;Croatia;Denmark;Estonia;Finland;France;Germany;Hungary;Israel;Italy;Netherlands;Norway;Portugal;Russian Federation;Serbia;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
      2019   Phase 3   EUCTR2017-002988-18-DK   Argentina;Australia;Austria;Belgium;Canada;Chile;Croatia;Denmark;Estonia;Finland;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Russian Federation;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
      2019   Phase 3   EUCTR2017-002988-18-AT   Argentina;Australia;Austria;Belgium;Canada;Chile;Croatia;Denmark;Estonia;Finland;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Russian Federation;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
      2018   Phase 3   EUCTR2017-002988-18-SE   Argentina;Australia;Austria;Belgium;Canada;Chile;Croatia;Denmark;Estonia;Finland;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Russian Federation;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
      2018   Phase 3   EUCTR2017-002988-18-NL   Argentina;Australia;Austria;Belgium;Canada;Chile;Croatia;Denmark;Estonia;Finland;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Russian Federation;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
      2018   Phase 3   EUCTR2017-002988-18-HU   Argentina;Australia;Austria;Belgium;Canada;Chile;Croatia;Denmark;Estonia;Finland;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Russian Federation;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
      2018   Phase 3   EUCTR2017-002988-18-ES   Argentina;Australia;Austria;Belgium;Canada;Chile;Croatia;Denmark;Estonia;Finland;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Russian Federation;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
      2018   Phase 3   EUCTR2017-002988-18-EE   Argentina;Australia;Austria;Belgium;Canada;Chile;Croatia;Denmark;Estonia;Finland;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Russian Federation;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
      2018   Phase 3   EUCTR2017-002988-18-DE   Argentina;Australia;Austria;Belgium;Canada;Chile;Croatia;Denmark;Estonia;Finland;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Russian Federation;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
      2018   Phase 3   EUCTR2017-002988-18-BE   Argentina;Australia;Austria;Belgium;Canada;Chile;Croatia;Denmark;Estonia;Finland;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Russian Federation;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
Corticoids+ tocilizumab 8mg/Kg/4 weeks   
   Centre Hospitalier Universitaire Dijon
      2013   Phase 2   NCT01910038   France;
Corticosteroid (CS)   
   AbbVie
      2019   Phase 3   NCT03725202   Australia;Austria;Belgium;Canada;Czechia;Denmark;France;Germany;Greece;Hungary;Israel;Italy;Japan;Netherlands;New Zealand;Norway;Portugal;Romania;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States;
Corticosteroids   
   Hoffmann-La Roche
      2013   Phase 3   NCT01791153   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
Corticosteroids for Systemic Use   
   University Hospital, Caen
      2020   Phase 3   NCT04012905   -
Cosentyx   
   NOVARTIS PHARMA AG
      2021   Phase 3   EUCTR2020-004809-31-IT   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Czechia;Denmark;Finland;France;Germany;Guatemala;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;South Africa;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
   Novartis Pharma AG
      2021   Phase 3   EUCTR2020-004809-31-PT   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Czechia;Denmark;Estonia;Finland;France;Germany;Guatemala;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;South Africa;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
      2021   Phase 3   EUCTR2020-004809-31-FR   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Czechia;Denmark;Estonia;Finland;France;Germany;Guatemala;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;South Africa;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
   Novartis Pharma GmbH
      2018   Phase 2   EUCTR2018-002610-12-DE   Germany;
Cosentyx 300 mg solution for injection in pre-filled syringe   
   Novartis Pharma AG
      2021   Phase 3   EUCTR2020-004809-31-NO   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Czechia;Denmark;Estonia;Finland;France;Germany;Guatemala;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;South Africa;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
      2021   Phase 3   EUCTR2020-004809-31-FI   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Czechia;Denmark;Estonia;Finland;France;Germany;Guatemala;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;South Africa;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
      2021   Phase 3   EUCTR2020-004809-31-DK   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Czechia;Denmark;Estonia;Finland;France;Germany;Guatemala;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;South Africa;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
      2021   Phase 3   EUCTR2020-004809-31-DE   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Czechia;Denmark;Estonia;Finland;France;Germany;Guatemala;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;South Africa;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
Cosentyx 300mg solution for injection in pre-filled syringe   
   Novartis Pharma AG
      2021   Phase 3   EUCTR2020-004809-31-BG   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Czechia;Denmark;Estonia;Finland;France;Germany;Guatemala;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;South Africa;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
Cyclophosphamide   
   Fairview University Medical Center
      2000   -   NCT00006055   United States;
Cyclosporine   
   Fairview University Medical Center
      2000   -   NCT00006055   United States;
Dotatate   
   University of Alberta
      2019   Phase 2   NCT03812302   Canada;
Encorton   
   F. Hoffmann-La Roche Ltd
      2013   Phase 3   EUCTR2011-006022-25-SE   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-PL   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-NL   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-IT   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-ES   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-DK   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-DE   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-BE   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-AT   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
   GlaxoSmithKline Research and Development Limited
      2016   Phase 3   EUCTR2015-001758-14-HU   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;Sweden;United Kingdom;United States;
Filgrastim   
   Fairview University Medical Center
      2000   -   NCT00006055   United States;
GSK2973327   
   GLAXOSMITHKLINE RESEARCH AND DEVELOPMENT
      2016   Phase 3   EUCTR2015-001758-14-IT   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;Sweden;United Kingdom;United States;
   GlaxoSmithKline Research and Development Limited
      2016   Phase 3   EUCTR2015-001758-14-NL   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;Sweden;United Kingdom;United States;
      2016   Phase 3   EUCTR2015-001758-14-HU   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;Sweden;United Kingdom;United States;
      2016   Phase 3   EUCTR2015-001758-14-BG   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;Sweden;United Kingdom;United States;
      2015   Phase 3   EUCTR2015-001758-14-ES   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;Sweden;United Kingdom;United States;
      2015   Phase 3   EUCTR2015-001758-14-DE   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;United Kingdom;United States;
      2015   Phase 3   EUCTR2015-001758-14-BE   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;Sweden;United Kingdom;United States;
Gevokizumab   
   Institut de Recherches Internationales Servier (IRIS)
      2015   -   EUCTR2013-002778-38-IE   Austria;Belgium;Canada;Czech Republic;Denmark;Estonia;Finland;France;Ireland;Italy;Norway;Poland;Russian Federation;Spain;Switzerland;United Kingdom;
      2015   -   EUCTR2013-002778-38-FI   Austria;Belgium;Canada;Czech Republic;Denmark;Estonia;Finland;France;Ireland;Italy;Norway;Poland;Russian Federation;Spain;Switzerland;United Kingdom;
      2015   -   EUCTR2013-002778-38-EE   Australia;Austria;Belgium;Canada;Czech Republic;Denmark;Estonia;Finland;France;Ireland;Italy;Norway;Poland;Russian Federation;Spain;Switzerland;United Kingdom;
      2015   -   EUCTR2013-002778-38-BE   Australia;Austria;Belgium;Canada;Czech Republic;Denmark;Estonia;Finland;France;Ireland;Italy;Norway;Poland;Russian Federation;Spain;Switzerland;United Kingdom;
      2014   Phase 2   EUCTR2013-002778-38-GB   Austria;Belgium;Canada;Czech Republic;Denmark;Estonia;Finland;France;Ireland;Italy;Norway;Poland;Russian Federation;Spain;Switzerland;United Kingdom;
      2014   Phase 2   EUCTR2013-002778-38-CZ   Australia;Austria;Belgium;Canada;Czech Republic;Denmark;Estonia;Finland;France;Ireland;Italy;Norway;Poland;Russian Federation;Spain;Switzerland;United Kingdom;
      2014   -   EUCTR2013-002778-38-DK   Australia;Austria;Belgium;Canada;Czech Republic;Denmark;Estonia;Finland;France;Ireland;Italy;Norway;Poland;Russian Federation;Spain;Switzerland;United Kingdom;
      2014   -   EUCTR2013-002778-38-AT   Australia;Austria;Belgium;Canada;Czech Republic;Denmark;Estonia;Finland;France;Ireland;Italy;Norway;Poland;Russian Federation;Spain;Switzerland;United Kingdom;
      2013   Phase 2   EUCTR2013-002778-38-IT   Australia;Austria;Belgium;Canada;Czech Republic;Denmark;Estonia;Finland;Ireland;Italy;Russian Federation;Spain;United Kingdom;
   Laboratorios Servier SL
      2014   -   EUCTR2013-002778-38-ES   Australia;Austria;Belgium;Canada;Czech Republic;Denmark;Estonia;Finland;Ireland;Russian Federation;Spain;United Kingdom;
Glucocorticoid Treatment   
   Bristol-Myers Squibb
      2017   Phase 3   NCT03192969   Australia;Austria;Belgium;Bulgaria;Canada;Denmark;Estonia;France;Germany;Greece;Ireland;Italy;Netherlands;Poland;Romania;Serbia;Spain;Sweden;Switzerland;United Kingdom;United States;
Glucocorticoids   
   University Hospital Inselspital, Berne
      2018   Phase 1/Phase 2   NCT03745586   Italy;Switzerland;
Guselkumab   
   Janssen Research & Development, LLC
      2020   Phase 2   NCT04633447   Belgium;Canada;France;Germany;Israel;Italy;Poland;Spain;United States;
   Janssen-Cilag International N.V.
      2021   Phase 2   EUCTR2020-000622-26-DE   Belgium;Canada;France;Germany;Israel;Italy;Poland;Spain;United States;
H02AB09   
   Copenhagen University Hospital Rigshospitalet
      2022   Phase 4   EUCTR2021-002528-18-DK   Denmark;
Hydrokortison orion   
   Copenhagen University Hospital Rigshospitalet
      2022   Phase 4   EUCTR2021-002528-18-DK   Denmark;
Hydroxychloroquine   
   University Hospital, Toulouse
      2002   Phase 3   NCT00430807   France;
Infliximab   
   Cambridge University Hospitals NHS Foundation Trust
      2020   Phase 2   EUCTR2019-003964-30-GB   United Kingdom;
   Centocor, Inc.
      2003   Phase 2   NCT00076726   Belgium;Italy;Spain;United Kingdom;United States;
KPL-301   
   Kiniksa Pharmaceuticals, Ltd. (Hamilton, Bermuda) c/o Kiniksa Pharmaceuticals Corp.
      2019   Phase 2   EUCTR2018-001003-36-HR   Australia;Belgium;Croatia;Estonia;Germany;Ireland;Italy;Netherlands;New Zealand;Poland;Serbia;Slovenia;Spain;United Kingdom;United States;
      2019   Phase 2   EUCTR2018-001003-36-DE   Australia;Belgium;Croatia;Estonia;Germany;Ireland;Italy;Netherlands;New Zealand;Poland;Serbia;Slovenia;Spain;United Kingdom;United States;
      2018   Phase 2   EUCTR2018-001003-36-SI   Australia;Belgium;Croatia;Estonia;Germany;Ireland;Italy;Netherlands;New Zealand;Poland;Serbia;Slovenia;Spain;United Kingdom;United States;
      2018   Phase 2   EUCTR2018-001003-36-NL   Australia;Belgium;Croatia;Estonia;Germany;Ireland;Italy;Netherlands;New Zealand;Poland;Serbia;Slovenia;Spain;United Kingdom;United States;
      2018   Phase 2   EUCTR2018-001003-36-IT   Australia;Belgium;Croatia;Estonia;Germany;Ireland;Italy;Netherlands;New Zealand;Poland;Serbia;Slovenia;Spain;United Kingdom;United States;
      2018   Phase 2   EUCTR2018-001003-36-GB   Australia;Belgium;Croatia;Estonia;Germany;Ireland;Italy;Netherlands;New Zealand;Poland;Serbia;Slovenia;Spain;United Kingdom;United States;
      2018   Phase 2   EUCTR2018-001003-36-ES   Australia;Belgium;Croatia;Estonia;Germany;Ireland;Italy;Netherlands;New Zealand;Poland;Serbia;Slovenia;Spain;United Kingdom;United States;
      2018   Phase 2   EUCTR2018-001003-36-EE   Australia;Belgium;Croatia;Estonia;Germany;Ireland;Italy;Netherlands;New Zealand;Poland;Serbia;Slovenia;Spain;United Kingdom;United States;
      2018   Phase 2   EUCTR2018-001003-36-BE   Australia;Belgium;Croatia;Estonia;Germany;Ireland;Italy;Netherlands;New Zealand;Poland;Serbia;Slovenia;Spain;United Kingdom;United States;
Kevzara ®   
   SANOFI-AVENTIS RECHERCHE E DEVELOPPEMENT
      2018   Phase 3   EUCTR2017-002988-18-IT   Argentina;Australia;Austria;Belgium;Canada;Chile;Croatia;Denmark;Estonia;Finland;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Russian Federation;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
   Sanofi-Aventis Recherche & Développement
      2019   Phase 3   EUCTR2017-002988-18-SI   Argentina;Australia;Austria;Belgium;Canada;Chile;Croatia;Denmark;Estonia;Finland;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Russian Federation;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
      2019   Phase 3   EUCTR2017-002988-18-PT   Argentina;Australia;Austria;Belgium;Canada;Chile;Croatia;Denmark;Estonia;Finland;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Russian Federation;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
      2019   Phase 3   EUCTR2017-002988-18-HR   Argentina;Australia;Austria;Belgium;Canada;Chile;Croatia;Denmark;Estonia;Finland;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Russian Federation;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
      2019   Phase 3   EUCTR2017-002988-18-GB   Argentina;Australia;Austria;Belgium;Canada;Chile;Croatia;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Russian Federation;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
      2019   Phase 3   EUCTR2017-002988-18-FR   Argentina;Australia;Austria;Belgium;Canada;Chile;Croatia;Denmark;Estonia;Finland;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Russian Federation;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
      2019   Phase 3   EUCTR2017-002988-18-FI   Argentina;Australia;Austria;Belgium;Canada;Croatia;Denmark;Estonia;Finland;France;Germany;Hungary;Israel;Italy;Netherlands;Norway;Portugal;Russian Federation;Serbia;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
      2019   Phase 3   EUCTR2017-002988-18-DK   Argentina;Australia;Austria;Belgium;Canada;Chile;Croatia;Denmark;Estonia;Finland;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Russian Federation;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
      2019   Phase 3   EUCTR2017-002988-18-AT   Argentina;Australia;Austria;Belgium;Canada;Chile;Croatia;Denmark;Estonia;Finland;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Russian Federation;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
      2018   Phase 3   EUCTR2017-002988-18-SE   Argentina;Australia;Austria;Belgium;Canada;Chile;Croatia;Denmark;Estonia;Finland;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Russian Federation;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
      2018   Phase 3   EUCTR2017-002988-18-NL   Argentina;Australia;Austria;Belgium;Canada;Chile;Croatia;Denmark;Estonia;Finland;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Russian Federation;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
      2018   Phase 3   EUCTR2017-002988-18-HU   Argentina;Australia;Austria;Belgium;Canada;Chile;Croatia;Denmark;Estonia;Finland;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Russian Federation;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
      2018   Phase 3   EUCTR2017-002988-18-ES   Argentina;Australia;Austria;Belgium;Canada;Chile;Croatia;Denmark;Estonia;Finland;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Russian Federation;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
      2018   Phase 3   EUCTR2017-002988-18-EE   Argentina;Australia;Austria;Belgium;Canada;Chile;Croatia;Denmark;Estonia;Finland;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Russian Federation;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
      2018   Phase 3   EUCTR2017-002988-18-DE   Argentina;Australia;Austria;Belgium;Canada;Chile;Croatia;Denmark;Estonia;Finland;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Russian Federation;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
      2018   Phase 3   EUCTR2017-002988-18-BE   Argentina;Australia;Austria;Belgium;Canada;Chile;Croatia;Denmark;Estonia;Finland;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Russian Federation;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
Lodotra (delayed release prednisolone)   
   Southend Hospital
      2012   -   EUCTR2011-005090-22-GB   United Kingdom;
METOJECT   
   CHU Dijon Bourgogne
      2019   Phase 3   EUCTR2018-002826-22-FR   France;
Methotrexate   
   Hoffmann-La Roche
      2013   Phase 3   NCT01791153   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
   The Cleveland Clinic
      1994   Phase 2   NCT00004686   -
Methotrexate treatment   
   Centre Hospitalier Universitaire Dijon
      2020   Phase 3   NCT03892785   France;
Methylprednisolone   
   Fairview University Medical Center
      2000   -   NCT00006055   United States;
Naltrexone Hydrochloride   
   University of Pennsylvania
      2019   Phase 2   NCT03482479   United States;
Nivolumab   
   Alliance Foundation Trials, LLC.
      2019   Phase 1   NCT03656627   United States;
Over encapsulated prednisone   
   GLAXOSMITHKLINE RESEARCH AND DEVELOPMENT
      2016   Phase 3   EUCTR2015-001758-14-IT   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;Sweden;United Kingdom;United States;
   GlaxoSmithKline Research and Development Limited
      2016   Phase 3   EUCTR2015-001758-14-NL   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;Sweden;United Kingdom;United States;
      2016   Phase 3   EUCTR2015-001758-14-HU   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;Sweden;United Kingdom;United States;
      2016   Phase 3   EUCTR2015-001758-14-BG   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;Sweden;United Kingdom;United States;
      2015   Phase 3   EUCTR2015-001758-14-ES   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;Sweden;United Kingdom;United States;
      2015   Phase 3   EUCTR2015-001758-14-DE   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;United Kingdom;United States;
      2015   Phase 3   EUCTR2015-001758-14-BE   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;Sweden;United Kingdom;United States;
PET10   
   University of Aarhus
      2014   -   NCT03285945   Denmark;
PET3   
   University of Aarhus
      2014   -   NCT03285945   Denmark;
Pr   
   AbbVie Deutschland GmbH & Co. KG
      2019   Phase 3   EUCTR2017-003978-13-RO   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Italy;Japan;Netherlands;New Zealand;Portugal;Romania;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-PT   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-NL   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-HU   Australia;Austria;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-GR   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-DK   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-DE   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Italy;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-BE   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Italy;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-AT   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
PredniSONE Tablets USP,   
   F. Hoffmann-La Roche Ltd
      2013   Phase 3   EUCTR2011-006022-25-SE   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-PT   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-PL   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-NL   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-IT   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-GB   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-ES   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-DK   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-DE   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-BE   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-AT   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
   Novartis Pharma AG
      2021   Phase 3   EUCTR2020-004809-31-NO   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Czechia;Denmark;Estonia;Finland;France;Germany;Guatemala;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;South Africa;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
      2021   Phase 3   EUCTR2020-004809-31-FI   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Czechia;Denmark;Estonia;Finland;France;Germany;Guatemala;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;South Africa;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
      2021   Phase 3   EUCTR2020-004809-31-DK   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Czechia;Denmark;Estonia;Finland;France;Germany;Guatemala;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;South Africa;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
      2021   Phase 3   EUCTR2020-004809-31-DE   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Czechia;Denmark;Estonia;Finland;France;Germany;Guatemala;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;South Africa;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
      2021   Phase 3   EUCTR2020-004809-31-BG   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Czechia;Denmark;Estonia;Finland;France;Germany;Guatemala;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;South Africa;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
Prednisolon 1 mg JENAPHARM   
   ABBVIE DEUTSCHLAND GMBH & CO. KG
      2019   Phase 3   EUCTR2017-003978-13-IT   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Italy;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
   AbbVie Deutschland GmbH & Co. KG
      2019   Phase 3   EUCTR2017-003978-13-RO   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Italy;Japan;Netherlands;New Zealand;Portugal;Romania;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-PT   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-NL   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-HU   Australia;Austria;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-GR   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-FR   Australia;Austria;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-ES   Australia;Austria;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-DK   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-DE   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Italy;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-BE   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Italy;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-AT   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
Prednisolon 10 mg JENAPHARM   
   ABBVIE DEUTSCHLAND GMBH & CO. KG
      2019   Phase 3   EUCTR2017-003978-13-IT   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Italy;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
Prednisolon 20 mg JENAPHARM   
   ABBVIE DEUTSCHLAND GMBH & CO. KG
      2019   Phase 3   EUCTR2017-003978-13-IT   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Italy;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
Prednisolon 5 mg JENAPHARM   
   ABBVIE DEUTSCHLAND GMBH & CO. KG
      2019   Phase 3   EUCTR2017-003978-13-IT   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Italy;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
   AbbVie Deutschland GmbH & Co. KG
      2019   Phase 3   EUCTR2017-003978-13-RO   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Italy;Japan;Netherlands;New Zealand;Portugal;Romania;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-PT   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-NL   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-HU   Australia;Austria;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-GR   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-FR   Australia;Austria;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-DK   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-DE   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Italy;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-BE   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Italy;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-AT   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
Prednisolone   
   Novartis Pharmaceuticals
      2019   Phase 2   NCT03765788   Germany;
Prednisolone 5 mg JENAPHARM   
   AbbVie Deutschland GmbH & Co. KG
      2019   Phase 3   EUCTR2017-003978-13-FR   Australia;Austria;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
Prednisone   
   Fairview University Medical Center
      2000   -   NCT00006055   United States;
   GlaxoSmithKline
      2015   Phase 3   NCT02531633   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;United Kingdom;United States;
   Hoffmann-La Roche
      2013   Phase 3   NCT01791153   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
   Kiniksa Pharmaceuticals, Ltd.
      2018   Phase 2   NCT03827018   Australia;Belgium;Croatia;Estonia;Germany;Ireland;Italy;Netherlands;New Zealand;Poland;Serbia;Slovenia;Spain;United Kingdom;United States;
   Massachusetts General Hospital
      2018   Phase 4   NCT03726749   United States;
      2016   Phase 1/Phase 2   NCT02955147   United States;
   Sanofi
      2018   Phase 3   NCT03600805   Argentina;Australia;Austria;Belgium;Canada;Croatia;Denmark;Estonia;Finland;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Russian Federation;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
   The Cleveland Clinic
      1994   Phase 2   NCT00004686   -
Prednisone Capsules   
   GlaxoSmithKline Research and Development Limited
      2016   Phase 3   EUCTR2015-001758-14-NL   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;Sweden;United Kingdom;United States;
      2016   Phase 3   EUCTR2015-001758-14-HU   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;Sweden;United Kingdom;United States;
      2016   Phase 3   EUCTR2015-001758-14-BG   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;Sweden;United Kingdom;United States;
      2015   Phase 3   EUCTR2015-001758-14-ES   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;Sweden;United Kingdom;United States;
      2015   Phase 3   EUCTR2015-001758-14-DE   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;United Kingdom;United States;
      2015   Phase 3   EUCTR2015-001758-14-BE   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;Sweden;United Kingdom;United States;
Prednisone Tablets, USP   
   Kiniksa Pharmaceuticals, Ltd. (Hamilton, Bermuda) c/o Kiniksa Pharmaceuticals Corp.
      2018   Phase 2   EUCTR2018-001003-36-GB   Australia;Belgium;Croatia;Estonia;Germany;Ireland;Italy;Netherlands;New Zealand;Poland;Serbia;Slovenia;Spain;United Kingdom;United States;
Prednisone and ustekinumab treatment   
   Centre Hospitalier Universitaire Dijon
      2019   Phase 2   NCT03711448   France;
Prednisone therapy and pharmacokinetic   
   University Hospital, Caen
      2009   Phase 4   NCT01400464   France;
Prednisone treatment   
   Centre Hospitalier Universitaire Dijon
      2020   Phase 3   NCT03892785   France;
      2019   Phase 2   NCT03711448   France;
Rituximab   
   Cambridge University Hospitals NHS Foundation Trust
      2020   Phase 2   EUCTR2019-003964-30-GB   United Kingdom;
Ro 001-9265/F02   
   F. Hoffmann-La Roche Ltd
      2013   Phase 3   EUCTR2011-006022-25-SE   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-PT   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-PL   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-NL   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-IT   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-GB   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-ES   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-DK   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-DE   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-BE   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-AT   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
Ro 001-9265/F03   
   F. Hoffmann-La Roche Ltd
      2013   Phase 3   EUCTR2011-006022-25-SE   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-PT   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-PL   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-NL   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-IT   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-GB   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-ES   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-DK   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-DE   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-BE   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-AT   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
Ro 001-9265/F04   
   F. Hoffmann-La Roche Ltd
      2013   Phase 3   EUCTR2011-006022-25-SE   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-PT   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-PL   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-NL   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-IT   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-GB   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-ES   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-DK   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-DE   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-BE   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-AT   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
Ro 487-7533/F10-04   
   F. Hoffmann-La Roche Ltd
      2013   Phase 3   EUCTR2011-006022-25-SE   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-PT   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-PL   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-NL   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-IT   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-GB   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-ES   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-DK   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-DE   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-BE   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-AT   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
RoActemra   
   CHU Dijon Bourgogne
      2019   Phase 3   EUCTR2018-002826-22-FR   France;
   F. Hoffmann-La Roche Ltd
      2013   Phase 3   EUCTR2011-006022-25-NL   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-GB   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-ES   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-DK   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-DE   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-BE   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-AT   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
RoActemra 162 mg solution for injection in pre-filled syringe   
   ROCHE SAS
      2017   Phase 3   EUCTR2016-002716-41-FR   France;
S78989   
   Institut de Recherches Internationales Servier (IRIS)
      2015   -   EUCTR2013-002778-38-IE   Austria;Belgium;Canada;Czech Republic;Denmark;Estonia;Finland;France;Ireland;Italy;Norway;Poland;Russian Federation;Spain;Switzerland;United Kingdom;
      2015   -   EUCTR2013-002778-38-FI   Austria;Belgium;Canada;Czech Republic;Denmark;Estonia;Finland;France;Ireland;Italy;Norway;Poland;Russian Federation;Spain;Switzerland;United Kingdom;
      2015   -   EUCTR2013-002778-38-EE   Australia;Austria;Belgium;Canada;Czech Republic;Denmark;Estonia;Finland;France;Ireland;Italy;Norway;Poland;Russian Federation;Spain;Switzerland;United Kingdom;
      2015   -   EUCTR2013-002778-38-BE   Australia;Austria;Belgium;Canada;Czech Republic;Denmark;Estonia;Finland;France;Ireland;Italy;Norway;Poland;Russian Federation;Spain;Switzerland;United Kingdom;
      2014   Phase 2   EUCTR2013-002778-38-GB   Austria;Belgium;Canada;Czech Republic;Denmark;Estonia;Finland;France;Ireland;Italy;Norway;Poland;Russian Federation;Spain;Switzerland;United Kingdom;
      2014   Phase 2   EUCTR2013-002778-38-CZ   Australia;Austria;Belgium;Canada;Czech Republic;Denmark;Estonia;Finland;France;Ireland;Italy;Norway;Poland;Russian Federation;Spain;Switzerland;United Kingdom;
      2014   -   EUCTR2013-002778-38-DK   Australia;Austria;Belgium;Canada;Czech Republic;Denmark;Estonia;Finland;France;Ireland;Italy;Norway;Poland;Russian Federation;Spain;Switzerland;United Kingdom;
      2014   -   EUCTR2013-002778-38-AT   Australia;Austria;Belgium;Canada;Czech Republic;Denmark;Estonia;Finland;France;Ireland;Italy;Norway;Poland;Russian Federation;Spain;Switzerland;United Kingdom;
      2013   Phase 2   EUCTR2013-002778-38-IT   Australia;Austria;Belgium;Canada;Czech Republic;Denmark;Estonia;Finland;Ireland;Italy;Russian Federation;Spain;United Kingdom;
   Laboratorios Servier SL
      2014   -   EUCTR2013-002778-38-ES   Australia;Austria;Belgium;Canada;Czech Republic;Denmark;Estonia;Finland;Ireland;Russian Federation;Spain;United Kingdom;
Sarilumab SAR153191   
   Sanofi
      2018   Phase 3   NCT03600805   Argentina;Australia;Austria;Belgium;Canada;Croatia;Denmark;Estonia;Finland;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Russian Federation;Slovenia;Spain;Sweden;Switzerland;United Kingdom;United States;
Secukinumab   
   Novartis Pharmaceuticals
      2021   Phase 3   NCT04930094   Australia;Belgium;Finland;France;Germany;Hungary;Poland;Portugal;Spain;Switzerland;Turkey;United States;
Secukinumab 300 mg, s.c.   
   Novartis Pharmaceuticals
      2019   Phase 2   NCT03765788   Germany;
Sirukumab   
   GLAXOSMITHKLINE RESEARCH AND DEVELOPMENT
      2016   Phase 3   EUCTR2015-001758-14-IT   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;Sweden;United Kingdom;United States;
   GlaxoSmithKline
      2015   Phase 3   NCT02531633   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;United Kingdom;United States;
   GlaxoSmithKline Research and Development Limited
      2016   Phase 3   EUCTR2015-001758-14-NL   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;Sweden;United Kingdom;United States;
      2016   Phase 3   EUCTR2015-001758-14-HU   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;Sweden;United Kingdom;United States;
      2016   Phase 3   EUCTR2015-001758-14-BG   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;Sweden;United Kingdom;United States;
      2015   Phase 3   EUCTR2015-001758-14-ES   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;Sweden;United Kingdom;United States;
      2015   Phase 3   EUCTR2015-001758-14-DE   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;United Kingdom;United States;
      2015   Phase 3   EUCTR2015-001758-14-BE   Australia;Belgium;Bulgaria;France;Germany;Hungary;Italy;Netherlands;New Zealand;Poland;Spain;Sweden;United Kingdom;United States;
TOCILIZUMAB SC   
   F. Hoffmann-La Roche Ltd
      2013   Phase 3   EUCTR2011-006022-25-NL   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
Tocilizumab   
    Clinical ImmunologySaitama Medical Center, Saitama Medical Universitity
   Assistance Publique - Hôpitaux de Paris
      2021   Phase 3   NCT04888221   France;
   Cambridge University Hospitals NHS Foundation Trust
      2020   Phase 2   EUCTR2019-003964-30-GB   United Kingdom;
   Department of Rheumatology &
   Hoffmann-La Roche
      2019   Phase 1   NCT03923738   Switzerland;
      2017   Phase 3   NCT03202368   France;
      2013   Phase 3   NCT01791153   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
   Hospital of Prato
      2015   Phase 4   NCT03244709   Italy;
   Massachusetts General Hospital
      2018   Phase 4   NCT03726749   United States;
   University Hospital Inselspital, Berne
      2018   Phase 1/Phase 2   NCT03745586   Italy;Switzerland;
Tocilizumab + Glucocorticoids (GCs)   
   University Hospital Inselspital, Berne
      2011   Phase 2   NCT01450137   Switzerland;
Tocilizumab Prefilled Syringe   
   Syneos Health
      2021   Phase 1   NCT04885829   Australia;New Zealand;
Tocilizumab SC   
   F. Hoffmann-La Roche Ltd
      2013   Phase 3   EUCTR2011-006022-25-PT   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-IT   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-GB   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-ES   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-DE   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-BE   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
      2013   Phase 3   EUCTR2011-006022-25-AT   Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Poland;Portugal;Spain;Sweden;United Kingdom;United States;
Tocilizumab and IV steroids combination   
   Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
      2020   Phase 2   NCT04239196   France;
Tocilizumab treatment   
   Centre Hospitalier Universitaire Dijon
      2020   Phase 3   NCT03892785   France;
Treatment   
   Centre Hospitalier Universitaire de Nice
      2019   Phase 3   NCT03841734   France;
Upadacitinib   
   ABBVIE DEUTSCHLAND GMBH & CO. KG
      2019   Phase 3   EUCTR2017-003978-13-IT   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Italy;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
   AbbVie
      2019   Phase 3   NCT03725202   Australia;Austria;Belgium;Canada;Czechia;Denmark;France;Germany;Greece;Hungary;Israel;Italy;Japan;Netherlands;New Zealand;Norway;Portugal;Romania;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States;
   AbbVie Deutschland GmbH & Co. KG
      2019   Phase 3   EUCTR2017-003978-13-RO   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Italy;Japan;Netherlands;New Zealand;Portugal;Romania;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-PT   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-NL   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-HU   Australia;Austria;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-GR   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-FR   Australia;Austria;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-ES   Australia;Austria;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-DK   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-DE   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Italy;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-BE   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Italy;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
      2019   Phase 3   EUCTR2017-003978-13-AT   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Greece;Hungary;Japan;Netherlands;New Zealand;Portugal;Russian Federation;Spain;United States;
Ustekinumab   
   Massachusetts General Hospital
      2016   Phase 1/Phase 2   NCT02955147   United States;
XOMA 052   
   Institut de Recherches Internationales Servier (IRIS)
      2015   -   EUCTR2013-002778-38-IE   Austria;Belgium;Canada;Czech Republic;Denmark;Estonia;Finland;France;Ireland;Italy;Norway;Poland;Russian Federation;Spain;Switzerland;United Kingdom;
      2015   -   EUCTR2013-002778-38-FI   Austria;Belgium;Canada;Czech Republic;Denmark;Estonia;Finland;France;Ireland;Italy;Norway;Poland;Russian Federation;Spain;Switzerland;United Kingdom;
      2015   -   EUCTR2013-002778-38-EE   Australia;Austria;Belgium;Canada;Czech Republic;Denmark;Estonia;Finland;France;Ireland;Italy;Norway;Poland;Russian Federation;Spain;Switzerland;United Kingdom;
      2015   -   EUCTR2013-002778-38-BE   Australia;Austria;Belgium;Canada;Czech Republic;Denmark;Estonia;Finland;France;Ireland;Italy;Norway;Poland;Russian Federation;Spain;Switzerland;United Kingdom;
      2014   Phase 2   EUCTR2013-002778-38-GB   Austria;Belgium;Canada;Czech Republic;Denmark;Estonia;Finland;France;Ireland;Italy;Norway;Poland;Russian Federation;Spain;Switzerland;United Kingdom;
      2014   Phase 2   EUCTR2013-002778-38-CZ   Australia;Austria;Belgium;Canada;Czech Republic;Denmark;Estonia;Finland;France;Ireland;Italy;Norway;Poland;Russian Federation;Spain;Switzerland;United Kingdom;
      2014   -   EUCTR2013-002778-38-DK   Australia;Austria;Belgium;Canada;Czech Republic;Denmark;Estonia;Finland;France;Ireland;Italy;Norway;Poland;Russian Federation;Spain;Switzerland;United Kingdom;
      2014   -   EUCTR2013-002778-38-AT   Australia;Austria;Belgium;Canada;Czech Republic;Denmark;Estonia;Finland;France;Ireland;Italy;Norway;Poland;Russian Federation;Spain;Switzerland;United Kingdom;
      2013   Phase 2   EUCTR2013-002778-38-IT   Australia;Austria;Belgium;Canada;Czech Republic;Denmark;Estonia;Finland;Ireland;Italy;Russian Federation;Spain;United Kingdom;
   Laboratorios Servier SL
      2014   -   EUCTR2013-002778-38-ES   Australia;Austria;Belgium;Canada;Czech Republic;Denmark;Estonia;Finland;Ireland;Russian Federation;Spain;United Kingdom;