42. Polyarteritis nodosa Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 15 / Drugs : 26 - (DrugBank : 16) / Drug target genes : 26 - Drug target pathways : 105
Polyarteritis nodosa and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
ID | Diseases (Sorted by score) | Score |
---|---|---|
42 | Polyarteritis nodosa | - |
46 | Malignant rheumatoid arthritis | 26.000 |
51 | Scleroderma | 24.251 |
85 | Idiopathic interstitial pneumonia | 20.963 |
49 | Systemic lupus erythematosus | 20.882 |
65 | Primary immunodeficiency | 19.443 |
93 | Primary biliary cholangitis | 18.022 |
56 | Behcet disease | 17.949 |
2 | Amyotrophic lateral sclerosis | 15.921 |
28 | Systemic amyloidosis | 15.357 |
45 | Eosinophilic granulomatosis with Polyangiitis | 15.316 |
26 | HTLV-1-associated myelopathy | 13.748 |
331 | Idiopathic multicentric castleman disease | 13.022 |
41 | Giant cell arteritis | 11.538 |
13 | Multiple sclerosis/Neuromyelitis optica | 11.491 |
40 | Takayasu arteritis | 11.157 |
96 | Crohn disease | 10.432 |
284 | Diamond-Blackfan anemia | 10.341 |
283 | Acquired pure red cell aplasia | 9.846 |
43 | Microscopic polyangiitis | 9.640 |
285 | Fanconi anemia | 9.317 |
55 | Relapsing polychondritis | 8.974 |
60 | Aplastic anemia | 8.512 |
11 | Myasthenia gravis | 8.378 |
266 | Familial mediterranean fever | 8.242 |
53 | Sjogren syndrome | 8.036 |
62 | Paroxysmal nocturnal hemoglobinuria | 7.978 |
162 | Pemphigoid | 7.888 |
164 | Oculocutaneous albinism | 7.819 |
19 | Lysosomal storage disease | 7.725 |
34 | Neurofibromatosis | 7.471 |
97 | Ulcerative colitis | 7.091 |
44 | Wegener granulomatosis | 6.777 |
226 | Interstitial cystitis with Hunners ulcer | 6.750 |
286 | Hereditary sideroblastic anemia | 6.361 |
50 | Dermatomyositis | 6.108 |
151 | Rasmussen encephalitis | 6.000 |
95 | Autoimmune hepatitis | 5.903 |
224 | Purpura nephritis | 5.415 |
38 | Stevens-Johnson syndrome | 5.415 |
61 | Autoimmune hemolytic anemia | 5.234 |
39 | Toxic epidermal necrolysis | 5.140 |
36 | Epidermolysis bullosa | 5.102 |
107 | Juvenile idiopathic arthritis | 5.030 |
6 | Parkinson disease | 5.025 |
302 | Leber hereditary optic neuropathy | 5.000 |
234 | Peroxisomal disease (except Adrenoleukodystrophy) | 4.869 |
222 | Primary nephrotic syndrome | 4.855 |
210 | Single Ventricle | 4.770 |
228 | Bronchiolitis obliterans | 4.720 |
66 | IgA nephropathy | 4.629 |
20 | Adrenoleukodystrophy | 4.476 |
35 | Pemphigus | 4.476 |
269 | Pyogenic arthritis | 4.272 |
64 | Thrombotic thrombocytopenic purpura | 4.123 |
326 | Osteopetrosis | 4.123 |
274 | Osteogenesis Imperfecta | 3.363 |
84 | Sarcoidosis | 3.002 |
160 | Congenital ichthyosis | 2.923 |
271 | Ankylosing spondylitis | 2.758 |
63 | Idiopathic thrombocytopenic purpura | 2.680 |
227 | Osler disease | 2.589 |
113 | Muscular dystrophy | 2.492 |
300 | IgG4-related disease | 2.308 |
94 | Primary sclerosing cholangitis | 2.024 |
58 | Hypertrophic cardiomyopathy | 1.962 |
90 | Retinitis pigmentosa | 1.950 |
16 | Crow-Fukase syndrome | 1.938 |
299 | Cystic fibrosis | 1.673 |
270 | Chronic recurrent multifocal osteomyelitis | 1.673 |
158 | Tuberous sclerosis | 1.538 |
172 | Hypophosphatasia | 1.385 |
298 | Hereditary pancreatitis | 1.343 |
10 | Charcot-Marie-Tooth disease | 1.070 |
256 | Muscle glycogenosis | 1.052 |
54 | Adult still disease | 1.000 |
52 | Mixed connective tissue disease | 1.000 |
220 | Rapidly progressive glomerulonephritis | 1.000 |
30 | Distal myopathy | 1.000 |