43. Microscopic polyangiitis Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 88 / Drugs : 81 - (DrugBank : 21) / Drug target genes : 15 - Drug target pathways : 90
Microscopic polyangiitis and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 43 | Microscopic polyangiitis | - |
| 44 | Wegener granulomatosis | 12.646 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 12.117 |
| 46 | Malignant rheumatoid arthritis | 10.397 |
| 42 | Polyarteritis nodosa | 9.640 |
| 51 | Scleroderma | 8.872 |
| 45 | Eosinophilic granulomatosis with Polyangiitis | 8.730 |
| 96 | Crohn disease | 7.313 |
| 41 | Giant cell arteritis | 6.662 |
| 11 | Myasthenia gravis | 6.429 |
| 53 | Sjogren syndrome | 6.312 |
| 49 | Systemic lupus erythematosus | 6.039 |
| 40 | Takayasu arteritis | 5.669 |
| 162 | Pemphigoid | 5.403 |
| 222 | Primary nephrotic syndrome | 5.021 |
| 84 | Sarcoidosis | 4.906 |
| 85 | Idiopathic interstitial pneumonia | 4.848 |
| 97 | Ulcerative colitis | 4.763 |
| 284 | Diamond-Blackfan anemia | 4.614 |
| 35 | Pemphigus | 4.614 |
| 285 | Fanconi anemia | 4.317 |
| 271 | Ankylosing spondylitis | 4.098 |
| 60 | Aplastic anemia | 4.083 |
| 50 | Dermatomyositis | 4.010 |
| 300 | IgG4-related disease | 3.943 |
| 226 | Interstitial cystitis with Hunners ulcer | 3.883 |
| 19 | Lysosomal storage disease | 3.855 |
| 65 | Primary immunodeficiency | 3.772 |
| 283 | Acquired pure red cell aplasia | 3.714 |
| 62 | Paroxysmal nocturnal hemoglobinuria | 3.551 |
| 331 | Idiopathic multicentric castleman disease | 3.235 |
| 164 | Oculocutaneous albinism | 3.176 |
| 66 | IgA nephropathy | 3.159 |
| 93 | Primary biliary cholangitis | 3.159 |
| 56 | Behcet disease | 3.143 |
| 55 | Relapsing polychondritis | 3.125 |
| 2 | Amyotrophic lateral sclerosis | 2.691 |
| 94 | Primary sclerosing cholangitis | 2.632 |
| 61 | Autoimmune hemolytic anemia | 2.429 |
| 107 | Juvenile idiopathic arthritis | 2.095 |
| 298 | Hereditary pancreatitis | 2.089 |
| 6 | Parkinson disease | 1.871 |
| 270 | Chronic recurrent multifocal osteomyelitis | 1.821 |
| 95 | Autoimmune hepatitis | 1.744 |
| 228 | Bronchiolitis obliterans | 1.489 |
| 172 | Hypophosphatasia | 1.429 |
| 36 | Epidermolysis bullosa | 1.376 |
| 70 | Spinal stenosis | 1.316 |
| 28 | Systemic amyloidosis | 1.316 |
| 10 | Charcot-Marie-Tooth disease | 1.286 |
| 86 | Pulmonary arterial hypertension | 1.257 |
| 14 | Chronic inflammatory demyelinating polyneuropathy | 1.232 |
| 224 | Purpura nephritis | 1.114 |
| 269 | Pyogenic arthritis | 1.114 |
| 54 | Adult still disease | 1.000 |
| 52 | Mixed connective tissue disease | 1.000 |
| 220 | Rapidly progressive glomerulonephritis | 1.000 |
| 30 | Distal myopathy | 1.000 |