DR info

Clinical trials : 993 / Drugs : 702 - (DrugBank : 184) / Drug target genes : 116 - Drug target pathways : 200

Systemic lupus erythematosus and other diseases between which drug repositioning might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Drug repositionability

ID	Diseases (Sorted by drug repositionability)
49	Systemic lupus erythematosus
46	Malignant rheumatoid arthritis
13	Multiple sclerosis/Neuromyelitis optica
96	Crohn disease
65	Primary immunodeficiency
97	Ulcerative colitis
93	Primary biliary cholangitis
51	Scleroderma
56	Behcet disease
2	Amyotrophic lateral sclerosis
53	Sjogren syndrome
60	Aplastic anemia
50	Dermatomyositis
42	Polyarteritis nodosa
66	IgA nephropathy
85	Idiopathic interstitial pneumonia
11	Myasthenia gravis
40	Takayasu arteritis
41	Giant cell arteritis
285	Fanconi anemia
28	Systemic amyloidosis
107	Juvenile idiopathic arthritis
222	Primary nephrotic syndrome
26	HTLV-1-associated myelopathy
19	Lysosomal storage disease
271	Ankylosing spondylitis
113	Muscular dystrophy
162	Pemphigoid
283	Acquired pure red cell aplasia
284	Diamond-Blackfan anemia
35	Pemphigus
6	Parkinson disease
331	Idiopathic multicentric castleman disease
61	Autoimmune hemolytic anemia
84	Sarcoidosis
55	Relapsing polychondritis
37	Generalised pustular psoriasis
300	IgG4-related disease
299	Cystic fibrosis
62	Paroxysmal nocturnal hemoglobinuria
160	Congenital ichthyosis
95	Autoimmune hepatitis
266	Familial mediterranean fever
210	Single Ventricle
44	Wegener granulomatosis
269	Pyogenic arthritis
224	Purpura nephritis
45	Eosinophilic granulomatosis with Polyangiitis
86	Pulmonary arterial hypertension
20	Adrenoleukodystrophy
228	Bronchiolitis obliterans
63	Idiopathic thrombocytopenic purpura
164	Oculocutaneous albinism
234	Peroxisomal disease (except Adrenoleukodystrophy)
78	Hypopituitarism
34	Neurofibromatosis
286	Hereditary sideroblastic anemia
64	Thrombotic thrombocytopenic purpura
326	Osteopetrosis
39	Toxic epidermal necrolysis
256	Muscle glycogenosis
226	Interstitial cystitis with Hunners ulcer
43	Microscopic polyangiitis
151	Rasmussen encephalitis
83	Addison disease
36	Epidermolysis bullosa
158	Tuberous sclerosis
94	Primary sclerosing cholangitis
25	Progressive multifocal leukoencephalopathy
16	Crow-Fukase syndrome
302	Leber hereditary optic neuropathy
38	Stevens-Johnson syndrome
75	Cushing disease
8	Huntington disease
270	Chronic recurrent multifocal osteomyelitis
76	Pituitary gonadotropin secretion hyperthyroidism
227	Osler disease
127	Frontotemporal lobar degeneration
274	Osteogenesis Imperfecta
206	Fragile X syndrome
265	Lipodystrophy
18	Spinocerebellar degeneration
15	Inclusion body myositis
17	Multiple system atrophy
90	Retinitis pigmentosa
81	Congenital adrenal hyperplasia
3	Spinal muscular atrophy
21	Mitochondrial disease
58	Hypertrophic cardiomyopathy
251	Urea cycle disorder
91	Budd-Chiari syndrome
202	Smith-Magenis syndrome
205	Fragile X syndrome related disease
70	Spinal stenosis
14	Chronic inflammatory demyelinating polyneuropathy
215	Tetralogy of Fallot
77	Growth hormone secreting pituitary adenoma
268	Nakajo-Nishimura syndrome
325	Hereditary autoinflammatory syndrome
337	Homocystinuria
257	Hepatic glycogenosis
139	Congenital cerebral hypomyelination
120	Hereditary dystonia
203	22q11.2 deletion syndrome
5	Progressive supranuclear palsy
278	Huge lymphatic malformation with cervicofacial lesion
211	Hypoplastic left heart syndrome
159	Xeroderma pigmentosum
156	Rett syndrome
98	Eosinophilic gastrointestinal disease
288	Autoimmune acquired coagulation factor deficiency
218	Alport syndrome
4	Primary lateral sclerosis
225	Congenital nephrogenic diabetes insipidus
296	Biliary atresia
171	Wilson disease
229	Autoimmune pulmonary alveolar proteinosis
172	Hypophosphatasia
80	Resistance to thyroid hormone
88	Chronic thromboembolic pulmonary hypertension
298	Hereditary pancreatitis
67	Polycystic kidney disease
212	Tricuspid atresia
89	Lymphangioleiomyomatosis
145	West syndrome
79	Homozygous familial hypercholesterolemia
301	Macular dystrophy
57	Idiopathic dilated cardiomyopathy
106	Cryopyrin-associated periodic syndrome
333	Hutchinson-Gilford syndrome
235	Hypoparathyroidism
137	Focal cortical dysplasia
192	Cockayne syndrome
277	Lymphangiomatosis
281	Klippel-Trenaunay-Weber syndrome
111	Congenital myopathy
54	Adult still disease
260	Sitosterolemia
52	Mixed connective tissue disease
220	Rapidly progressive glomerulonephritis
30	Distal myopathy