55. Relapsing polychondritis Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 8 / Drugs : 10 - (DrugBank : 9) / Drug target genes : 12 - Drug target pathways : 101
Relapsing polychondritis and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 55 | Relapsing polychondritis | - |
| 13 | Multiple sclerosis/Neuromyelitis optica | 12.000 |
| 46 | Malignant rheumatoid arthritis | 12.000 |
| 49 | Systemic lupus erythematosus | 12.000 |
| 51 | Scleroderma | 12.000 |
| 53 | Sjogren syndrome | 12.000 |
| 50 | Dermatomyositis | 12.000 |
| 41 | Giant cell arteritis | 12.000 |
| 284 | Diamond-Blackfan anemia | 10.542 |
| 285 | Fanconi anemia | 10.419 |
| 60 | Aplastic anemia | 10.323 |
| 11 | Myasthenia gravis | 10.307 |
| 107 | Juvenile idiopathic arthritis | 10.277 |
| 19 | Lysosomal storage disease | 10.229 |
| 65 | Primary immunodeficiency | 10.195 |
| 97 | Ulcerative colitis | 10.154 |
| 96 | Crohn disease | 10.143 |
| 42 | Polyarteritis nodosa | 8.974 |
| 164 | Oculocutaneous albinism | 8.824 |
| 93 | Primary biliary cholangitis | 8.810 |
| 56 | Behcet disease | 8.796 |
| 45 | Eosinophilic granulomatosis with Polyangiitis | 7.875 |
| 40 | Takayasu arteritis | 7.560 |
| 162 | Pemphigoid | 7.364 |
| 222 | Primary nephrotic syndrome | 7.082 |
| 286 | Hereditary sideroblastic anemia | 6.635 |
| 160 | Congenital ichthyosis | 6.519 |
| 283 | Acquired pure red cell aplasia | 6.519 |
| 95 | Autoimmune hepatitis | 6.456 |
| 151 | Rasmussen encephalitis | 6.000 |
| 326 | Osteopetrosis | 5.359 |
| 62 | Paroxysmal nocturnal hemoglobinuria | 5.056 |
| 302 | Leber hereditary optic neuropathy | 5.000 |
| 39 | Toxic epidermal necrolysis | 4.636 |
| 271 | Ankylosing spondylitis | 4.581 |
| 84 | Sarcoidosis | 4.332 |
| 85 | Idiopathic interstitial pneumonia | 4.290 |
| 274 | Osteogenesis Imperfecta | 4.286 |
| 2 | Amyotrophic lateral sclerosis | 4.202 |
| 38 | Stevens-Johnson syndrome | 4.200 |
| 269 | Pyogenic arthritis | 4.200 |
| 64 | Thrombotic thrombocytopenic purpura | 4.125 |
| 44 | Wegener granulomatosis | 3.857 |
| 20 | Adrenoleukodystrophy | 3.818 |
| 227 | Osler disease | 3.783 |
| 61 | Autoimmune hemolytic anemia | 3.720 |
| 228 | Bronchiolitis obliterans | 3.545 |
| 66 | IgA nephropathy | 3.514 |
| 26 | HTLV-1-associated myelopathy | 3.474 |
| 63 | Idiopathic thrombocytopenic purpura | 3.400 |
| 58 | Hypertrophic cardiomyopathy | 3.375 |
| 36 | Epidermolysis bullosa | 3.367 |
| 234 | Peroxisomal disease (except Adrenoleukodystrophy) | 3.299 |
| 226 | Interstitial cystitis with Hunners ulcer | 3.281 |
| 28 | Systemic amyloidosis | 3.273 |
| 43 | Microscopic polyangiitis | 3.125 |
| 6 | Parkinson disease | 3.096 |
| 224 | Purpura nephritis | 3.056 |
| 331 | Idiopathic multicentric castleman disease | 2.554 |
| 158 | Tuberous sclerosis | 2.500 |
| 90 | Retinitis pigmentosa | 2.381 |
| 113 | Muscular dystrophy | 2.331 |
| 299 | Cystic fibrosis | 2.235 |
| 300 | IgG4-related disease | 2.044 |
| 270 | Chronic recurrent multifocal osteomyelitis | 1.875 |
| 35 | Pemphigus | 1.818 |
| 172 | Hypophosphatasia | 1.444 |
| 54 | Adult still disease | 1.000 |
| 52 | Mixed connective tissue disease | 1.000 |