58. Hypertrophic cardiomyopathy Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 126 / Drugs : 135 - (DrugBank : 42) / Drug target genes : 46 - Drug target pathways : 162
Drugs and their primary sponsors and trial info
(R)-N-(5-(5-ETHYL-1,2,4-OXADIAZOL-3-YL)-2,3-DIHYDRO-1H-INDEN-1-YL)-1-METHYL-1H-PYRAZOLE-4-CARBOXAMIDE
Cytokinetics, Inc.
2021 Phase 2 EUCTR2020-003571-17-ES Italy;Spain;United States;
2020 Phase 2 EUCTR2019-002785-12-GB Italy;Netherlands;Spain;United Kingdom;United States;
2020 Phase 2 EUCTR2019-002785-12-ES Italy;Netherlands;Spain;United Kingdom;United States;
- Phase 2 EUCTR2019-002785-12-NL Italy;Netherlands;Spain;United Kingdom;United States;
(R)-N-(5-(5-ETHYL-1,2,4-OXADIAZOL-3-YL)-2,3-DIHYDRO-1H-INDEN-1-YL)-1METHYL-1H-PYRAZOLE-4-CARBOXAMIDE
CYTOKINETICS, INC.
2021 Phase 2 EUCTR2020-003571-17-IT Italy;Spain;United States;
2020 Phase 2 EUCTR2019-002785-12-IT Italy;Netherlands;Spain;United Kingdom;United States;
(R)-N-(5-(5-ETHYL-1,2,4-OXADIAZOL-3-YL)-2,3-DIHYDRO-1H-INDEN-1-YL)-1METHYL-1HPYRAZOLE-4-CARBOXAMIDE
CYTOKINETICS, INC.
2021 Phase 2 EUCTR2020-003571-17-IT Italy;Spain;United States;
1-(2,3,4-Trimethoxybenzyl)piperazine dihydrochloride
University College London (UCL)
2011 - EUCTR2011-000038-12-GB United Kingdom;
3D electrocardiographic mapping (ECM)
University Hospital, Bordeaux
2015 - NCT02559726 France;
Adenosine
Duke University
2017 Phase 4 NCT03249272 United States;
Air
University Hospital, Bordeaux
2019 - NCT04129905 France;
Alcohol
Beijing Anzhen Hospital, Capital Medical University
2021 - ChiCTR2000041464 China;
Sir Run Run Shaw Hospital, Zhejiang University School of Medicine
2020 Phase 0 ChiCTR2000033626 China;
Alcohol Septal Ablation
St. Antonius Hospital
2021 - NCT04684290 Netherlands;
Alcohol septal ablation
Steen Hvitfeldt Poulsen
2019 - NCT04066777 Denmark;
Amyl nitrite inhalation
Mayo Clinic
2021 - NCT04905173 United States;
Antiarrhythmic drugs
Institute of Cardiology, Warsaw, Poland
2009 Phase 3 NCT00821353 Poland;
Aspirin
Ottawa Heart Institute Research Corporation
2016 Phase 3 NCT02674958 Canada;
Atorvastatin
University of Calgary
2007 Phase 3 NCT00317967 Canada;
B-lines SE
Fatebenefratelli Hospital
2016 - NCT03049995 Italy;
BNP blood sample test
University Hospital, Bordeaux
2019 - NCT04129905 France;
C01EB18
OSPEDALE SAN RAFFAELE
2016 Phase 2 EUCTR2015-004402-42-IT Italy;
CAS Name: 1,4-Benzoxazepin-5(2H)-one, 3,4-dihydro-4-(2-pyrimidinylmethyl)-7-[4- (trifluoromethoxy)phenyl] IUPAC Name: 4-(Pyrimidin-2-ylmethyl)-7-[4- (trifluoromethoxy)phenyl]-3,4-dihydro-1,4-benzoxazepin-5(2H)-one
Gilead Sciences, Inc.
2015 Phase 2 EUCTR2013-004429-97-GB Australia;France;Germany;Israel;Italy;Netherlands;United Kingdom;United States;
CAS Name: 1,4-Benzoxazepin-5(2H)-one, 3,4-dihydro-4-(2-pyrimidinylmethyl)-7-[4-(trifluoromethoxy)phenyl] IUPAC Name: 4-(Pyrimidin-2-ylmethyl)-7-[4-(trifluoromethoxy)phenyl]-3,4-dihydro-1,4-benzoxazepin-5(2H)-one
Gilead Sciences, Inc.
2015 Phase 2 EUCTR2013-004429-97-NL France;Germany;Israel;Italy;Netherlands;United Kingdom;United States;
2015 Phase 2 EUCTR2013-004429-97-IT France;Germany;Israel;Italy;Netherlands;United Kingdom;United States;
2015 Phase 2 EUCTR2013-004429-97-GB Australia;France;Germany;Israel;Italy;Netherlands;United Kingdom;United States;
CK-3773274
CYTOKINETICS, INC.
2021 Phase 2 EUCTR2020-003571-17-IT Italy;Spain;United States;
2020 Phase 2 EUCTR2019-002785-12-IT Italy;Netherlands;Spain;United Kingdom;United States;
Cytokinetics, Inc.
2021 Phase 2 EUCTR2020-003571-17-ES Italy;Spain;United States;
2020 Phase 2 EUCTR2019-002785-12-GB Italy;Netherlands;Spain;United Kingdom;United States;
2020 Phase 2 EUCTR2019-002785-12-ES Italy;Netherlands;Spain;United Kingdom;United States;
- Phase 2 EUCTR2019-002785-12-NL Italy;Netherlands;Spain;United Kingdom;United States;
Ji Xing Pharmaceuticals (Shanghai) Co., Ltd.
2021 Phase 1 NCT04783766 China;
CK-3773274 (10 - 30 mg)
Cytokinetics
2020 Phase 2 NCT04219826 Italy;Netherlands;Spain;United States;
CK-3773274 (5 - 15 mg)
Cytokinetics
2020 Phase 2 NCT04219826 Italy;Netherlands;Spain;United States;
CK-3773274 (5 - 20 mg)
Cytokinetics
2021 Phase 2 NCT04848506 Italy;Spain;United States;
CK-3773274 (5 mg, 10 mg, 15 mg and 20 mg)
Cytokinetics
2022 Phase 3 NCT05186818 United States;
CK-3773274 - Granules in Capsule
Cytokinetics
2018 Phase 1 NCT03767855 United States;
CK-3773274 - Tablets
Cytokinetics
2018 Phase 1 NCT03767855 United States;
CT-G20
Celltrion
2020 Phase 1 NCT04418297 Korea, Republic of;Poland;United States;
Candesartan
Charles University, Czech Republic
2007 Phase 2 NCT00430833 Czech Republic;
The First Affiliated Hospital, Sun Yat-sen University
2018 Phase 4 study ChiCTR-IIR-17013661 China;
Carnitine
University Health Network, Toronto
2013 Phase 4 NCT01904396 Canada;
Cibenzoline
TOA EIYO LTD.
2019 Phase 2 JPRN-JapicCTI-194910 Japan;
Coronary flow reserve SE
Fatebenefratelli Hospital
2016 - NCT03049995 Italy;
Cufence
Manchester University NHS Foundation Trust
2020 Phase 2 EUCTR2020-002242-17-GB United Kingdom;
Cyclosporine A
National Heart, Lung, and Blood Institute (NHLBI)
1999 Phase 2 NCT00001965 United States;
Diastolic function SE
Fatebenefratelli Hospital
2016 - NCT03049995 Italy;
Diltiazem
Brigham and Women's Hospital
2006 Phase 2/Phase 3 NCT00319982 United States;
Diovan
National Heart, Lung, and Blood Institute / National Institutes of Health
2016 Phase 2 EUCTR2015-002283-16-DK Denmark;
Dobutamine
University of Aarhus
2011 Phase 4 NCT01375335 Denmark;
Echo and myocardial contrast echocardiography perfusion imaging
Oregon Health and Science University
2015 - NCT02560467 United States;
Echocardiography (TEE)
University Hospital, Bordeaux
2015 - NCT02559726 France;
Eleclazine
Gilead Sciences
2015 Phase 2/Phase 3 NCT02291237 Australia;France;Germany;Israel;Italy;Netherlands;United Kingdom;United States;
Endothelial function biomarkers
University Hospital, Bordeaux
2019 - NCT04129905 France;
Entresto
Novartis Farmacéutica, S.A.
2020 Phase 2 EUCTR2019-003098-24-ES Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
Novartis Pharma AG
2020 Phase 2 EUCTR2019-003098-24-GR Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
2020 Phase 2 EUCTR2019-003098-24-GB Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
2020 Phase 2 EUCTR2019-003098-24-FI Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
2019 Phase 2 EUCTR2019-003098-24-DE Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
Esmolol
Meshalkin Research Institute of Pathology of Circulation
2021 Phase 4 NCT05073094 Russian Federation;
GS-6615
Gilead Sciences, Inc.
2015 Phase 2 EUCTR2013-004429-97-NL France;Germany;Israel;Italy;Netherlands;United Kingdom;United States;
2015 Phase 2 EUCTR2013-004429-97-IT France;Germany;Israel;Italy;Netherlands;United Kingdom;United States;
GS-6615 3 mg Pink
Gilead Sciences, Inc.
2015 Phase 2 EUCTR2013-004429-97-GB Australia;France;Germany;Israel;Italy;Netherlands;United Kingdom;United States;
GS-6615 3 mg White
Gilead Sciences, Inc.
2015 Phase 2 EUCTR2013-004429-97-GB Australia;France;Germany;Israel;Italy;Netherlands;United Kingdom;United States;
GS-6615 6 mg White
Gilead Sciences, Inc.
2015 Phase 2 EUCTR2013-004429-97-GB Australia;France;Germany;Israel;Italy;Netherlands;United Kingdom;United States;
Gold
Beijing Chaoyang Hospital, Capital Medical University
2021 Phase 0 ChiCTR2100048388 China;
Gutron 2,
CHU de Bordeaux
2015 - EUCTR2015-003521-34-FR France;
Hyperpolarized 13C-Pyruvate
University of Texas Southwestern Medical Center
2018 - NCT03057002 United States;
IMB-1018972
Imbria Pharmaceuticals, Inc.
2021 Phase 2 NCT04826185 United Kingdom;United States;
IMUKIN - 6 FLACONI 0.5 ML 100 MCG
ASSOCIAZIONE LA NOSTRA FAMIGLIA - SEZIONE SCIENTIFICA I.R.C.C.S. E.MEDEA
2016 Phase 2 EUCTR2015-002432-40-IT Italy;
Insertable cardiac monitor
Region Gävleborg
2017 - NCT03259113 Sweden;
LCZ696
Novartis Farmacéutica, S.A.
2020 Phase 2 EUCTR2019-003098-24-ES Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
Novartis Pharma AG
2020 Phase 2 EUCTR2019-003098-24-GR Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
2020 Phase 2 EUCTR2019-003098-24-GB Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
2020 Phase 2 EUCTR2019-003098-24-FI Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
2019 Phase 2 EUCTR2019-003098-24-DE Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
Novartis Pharmaceuticals
2020 Phase 2 NCT04164732 Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
Left ventricular contractile reserve SE
Fatebenefratelli Hospital
2016 - NCT03049995 Italy;
Left ventricular outflow tract gradient SE
Fatebenefratelli Hospital
2016 - NCT03049995 Italy;
Losartan
Henning Bundgaard
2011 Phase 2 NCT01447654 Denmark;
Massachusetts General Hospital
2007 Phase 2 NCT01150461 United States;
National Heart, Lung, and Blood Institute (NHLBI)
1996 - NCT00001534 United States;
Losartan Bluefish
Hjertemedicinsk klinik B, 2142, Rigshospitalet
2011 - EUCTR2011-001191-19-DK Denmark;
MEK162
Array Biopharma, now a wholly owned subsidiary of Pfizer
2012 Phase 2 NCT01556568 United Kingdom;United States;
Novartis Pharma Services AG
2012 - EUCTR2011-003392-10-GB United Kingdom;United States;
METOPROLOL SUCCINATE
Aarhus University Hospital
2018 Phase 2 EUCTR2017-004478-32-DK Denmark;
MIDODRINE HYDROCHLORIDE
CHU de Bordeaux
2015 - EUCTR2015-003521-34-FR France;
MYK-461
MYOKARDIA, INC.
2019 Phase 3 EUCTR2018-004039-64-IT Belgium;Czechia;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2018 Phase 3 EUCTR2017-002530-23-IT Belgium;Czech Republic;Czechia;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
MyoKardia, Inc.
2019 Phase 3 EUCTR2018-004039-64-PT Belgium;Czechia;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2019 Phase 3 EUCTR2018-004039-64-PL Belgium;Czechia;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2019 Phase 3 EUCTR2018-004039-64-NL Belgium;Czechia;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2019 Phase 3 EUCTR2018-004039-64-GB Belgium;Czech Republic;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2019 Phase 3 EUCTR2018-004039-64-ES Belgium;Czech Republic;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2019 Phase 3 EUCTR2018-004039-64-DK Belgium;Czechia;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2019 Phase 3 EUCTR2018-004039-64-DE Belgium;Czechia;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2019 Phase 3 EUCTR2018-004039-64-BE Belgium;Czechia;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2018 Phase 3 EUCTR2017-002530-23-PT Belgium;Czech Republic;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2018 Phase 3 EUCTR2017-002530-23-PL Belgium;Czech Republic;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2018 Phase 3 EUCTR2017-002530-23-NL Belgium;Czech Republic;Czechia;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2018 Phase 3 EUCTR2017-002530-23-GB Belgium;Czech Republic;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2018 Phase 3 EUCTR2017-002530-23-FR Belgium;Czech Republic;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2018 Phase 3 EUCTR2017-002530-23-ES Belgium;Czech Republic;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2018 Phase 3 EUCTR2017-002530-23-DK Belgium;Czech Republic;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2018 Phase 3 EUCTR2017-002530-23-DE Belgium;Czech Republic;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2018 Phase 3 EUCTR2017-002530-23-CZ Belgium;Czech Republic;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2018 Phase 3 EUCTR2017-002530-23-BE Belgium;Czech Republic;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2016 Phase 2 NCT02842242 United States;
2014 Phase 1 NCT02329184 United States;
Magnetic resonance imaging (MRI) with gadolinium enhancement
University Hospital, Bordeaux
2015 - NCT02559726 France;
Magnetic resonance imaging (MRI) without gadolinium enhancement
University Hospital, Bordeaux
2015 - NCT02559726 France;
Mangafodipir
University of Edinburgh
2018 - NCT03607669 United Kingdom;
Mavacamten
LianBio LLC
2022 Phase 3 NCT05174416 China;
2021 Phase 1 NCT05135871 China;
MYOKARDIA, INC.
2018 Phase 3 EUCTR2017-002530-23-IT Belgium;Czech Republic;Czechia;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
MyoKardia, Inc.
2020 Phase 3 NCT04349072 United States;
2018 Phase 3 NCT03470545 Belgium;Czechia;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2018 Phase 2/Phase 3 NCT03723655 Belgium;Czechia;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2018 Phase 2 NCT03496168 United States;
2018 Phase 2 NCT03442764 United States;
Metoprolol
The First Affiliated Hospital, Sun Yat-sen University
2018 Phase 4 study ChiCTR-IIR-17013661 China;
University Hospital, Motol
2020 Phase 4 NCT04133532 Czechia;
Metoprolol Succinate
Steen Hvitfeldt Poulsen
2018 Phase 2 NCT03532802 Denmark;
Metoprololsuccinat
Aarhus University Hospital
2018 Phase 2 EUCTR2017-004478-32-DK Denmark;
Mitral regurgitation SE
Fatebenefratelli Hospital
2016 - NCT03049995 Italy;
N-acetylcysteine
The University of Texas Health Science Center, Houston
2012 Phase 1 NCT01537926 United States;
NO
West China Hospital, Sichuan University
2019 - ChiCTR1900021706 China;
PERINDOPRIL ARGININA
AZIENDA OSPEDALIERO-UNIVERSITARIA CAREGGI
2017 Phase 2 EUCTR2015-004317-24-IT Italy;
PROCAPTAN - 10 MG COMPRESSE RIVESTITE CON FILM 60 COMPRESSE IN CONTENITORE PER COMPRESSE PP
AZIENDA OSPEDALIERO-UNIVERSITARIA CAREGGI
2017 Phase 2 EUCTR2015-004317-24-IT Italy;
PROCAPTAN - 5 MG COMPRESSE RIVESTITE CON FILM 10 COMPRESSE IN CONTENITORE PER COMPRESSE PP
AZIENDA OSPEDALIERO-UNIVERSITARIA CAREGGI
2017 Phase 2 EUCTR2015-004317-24-IT Italy;
Perhexiline
Flinders University
2020 Phase 2 NCT04426578 Australia;
Heart Metabolics Limited
2015 Phase 3 NCT02431221 -
University Hospital Birmingham
2006 Phase 2 NCT00500552 United Kingdom;
Perindopril arginine
AZIENDA OSPEDALIERO-UNIVERSITARIA CAREGGI
2017 Phase 2 EUCTR2015-004317-24-IT Italy;
Perxexiline
University Hospital of Birmingham Foundation Trust
2005 - EUCTR2005-000755-15-GB United Kingdom;
Pexsig
University Hospital of Birmingham Foundation Trust
2005 - EUCTR2005-000755-15-GB United Kingdom;
Phosphorous
University of East Anglia
2017 Phase 1 NCT03251287 United Kingdom;
Pirfenidone
National Heart, Lung, and Blood Institute (NHLBI)
2001 Phase 2 NCT00011076 United States;
Pre and post-CPB Drug: Dobutamine Hydrochloride
University Health Network, Toronto
2021 Phase 4 NCT05025644 -
Pulmonary hemodynamics SE
Fatebenefratelli Hospital
2016 - NCT03049995 Italy;
RANEXA - 750 MG - COMPRESSA A RILASCIO PROLUNGATO- USO ORALE - BLISTER (PVC/PVDC/ALLUMINIO) 60 COMPRESSE
OSPEDALE SAN RAFFAELE
2016 Phase 2 EUCTR2015-004402-42-IT Italy;
RANEXA*60CPR 500MG R.P.
MENARINI INTERNATIONAL OPERATIONS LUXEMBOURG S.A.
2012 Phase 2 EUCTR2011-004507-20-IT Germany;Italy;Spain;
RANEXA*60CPR 750MG R.P.
MENARINI INTERNATIONAL OPERATIONS LUXEMBOURG S.A.
2012 Phase 2 EUCTR2011-004507-20-IT Germany;Italy;Spain;
RAS
Shanghai Children's Medical Center affiliated to Shanghai Jiao Tong University School of Medicine
2021 - ChiCTR2000041243 China;
RF catheter ablation
Institute of Cardiology, Warsaw, Poland
2009 Phase 3 NCT00821353 Poland;
Ranexa
Menarini International Operations Luxembourg S.A.
2012 - EUCTR2011-004507-20-ES Germany;Italy;Spain;
2012 - EUCTR2011-004507-20-DE Germany;Italy;Spain;
Ranolazina Ranexa
OSPEDALE SAN RAFFAELE
2016 Phase 2 EUCTR2015-004402-42-IT Italy;
Ranolazine
Duke University
2012 Phase 4 NCT01721967 United States;
Ranolazine 1000 mg PR tablets
Menarini International Operations Luxembourg S.A.
2012 - EUCTR2011-004507-20-ES Germany;Italy;Spain;
2012 - EUCTR2011-004507-20-DE Germany;Italy;Spain;
Ranolazine 500 mg PR tablets
Menarini International Operations Luxembourg S.A.
2012 - EUCTR2011-004507-20-ES Germany;Italy;Spain;
2012 - EUCTR2011-004507-20-DE Germany;Italy;Spain;
Ranolazine 750 mg PR tablets
Menarini International Operations Luxembourg S.A.
2012 - EUCTR2011-004507-20-ES Germany;Italy;Spain;
2012 - EUCTR2011-004507-20-DE Germany;Italy;Spain;
Ranolazine PR (prolonged-release) 500 mg 1 tablet bis in die and 750 mg 1 tablet bis in die
IRCCS San Raffaele
2016 Phase 2 NCT03953989 Italy;
Regadenoson
Duke University
2017 Phase 4 NCT03249272 United States;
SACUBITRIL VALSARTAN
Novartis Farmacéutica, S.A.
2020 Phase 2 EUCTR2019-003098-24-ES Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
Novartis Pharma AG
2020 Phase 2 EUCTR2019-003098-24-GR Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
2020 Phase 2 EUCTR2019-003098-24-GB Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
2020 Phase 2 EUCTR2019-003098-24-FI Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
2019 Phase 2 EUCTR2019-003098-24-DE Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
Sacubitril/Valsartan
Newcastle University
2019 Phase 2 NCT03832660 Germany;Italy;Serbia;United Kingdom;
Sacubitril/valsartan
Novartis Farmacéutica, S.A.
2020 Phase 2 EUCTR2019-003098-24-ES Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
Novartis Pharma AG
2020 Phase 2 EUCTR2019-003098-24-GR Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
2020 Phase 2 EUCTR2019-003098-24-GB Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
2020 Phase 2 EUCTR2019-003098-24-FI Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
2019 Phase 2 EUCTR2019-003098-24-DE Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
Spironolactone
Tufts Medical Center
2007 Phase 4 NCT00879060 United States;
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
2018 Phase 4 NCT02948998 China;
Surgical Septal Myectomy
St. Antonius Hospital
2021 - NCT04684290 Netherlands;
TY-0305
TOA EIYO LTD.
2019 Phase 2 JPRN-JapicCTI-194910 Japan;
Trans-right ventricular alcohol septal ablation (TRVASA)
National Heart, Lung, and Blood Institute (NHLBI)
2002 Phase 2 NCT00035386 United States;
Treatment BX1514M
University Hospital, Bordeaux
2015 Phase 2 NCT02590809 France;
Trientine
Manchester University NHS Foundation Trust
2020 Phase 2 NCT04706429 United Kingdom;
2020 Phase 2 EUCTR2020-002242-17-GB United Kingdom;
Triethylinetetramine dihydrochloride
Manchester University NHS Foundation Trust
2020 Phase 2 EUCTR2020-002242-17-GB United Kingdom;
Trimetazidine
University College, London
2012 Phase 2 NCT01696370 United Kingdom;
Use of bioanalytical assay to monitor plasma levels of perhexiline
Heart Metabolics Limited
2016 Phase 2 NCT02862600 United States;
Valsartan
HealthCore-NERI
2014 Phase 2 NCT01912534 Canada;United States;
Vastarel
VU University Medical Center
2018 Phase 2 EUCTR2018-000029-29-NL Netherlands;
Vastarel 20mg film coated tablets
University College London (UCL)
2011 - EUCTR2011-000038-12-GB United Kingdom;
Cytokinetics, Inc.
2021 Phase 2 EUCTR2020-003571-17-ES Italy;Spain;United States;
2020 Phase 2 EUCTR2019-002785-12-GB Italy;Netherlands;Spain;United Kingdom;United States;
2020 Phase 2 EUCTR2019-002785-12-ES Italy;Netherlands;Spain;United Kingdom;United States;
- Phase 2 EUCTR2019-002785-12-NL Italy;Netherlands;Spain;United Kingdom;United States;
(R)-N-(5-(5-ETHYL-1,2,4-OXADIAZOL-3-YL)-2,3-DIHYDRO-1H-INDEN-1-YL)-1METHYL-1H-PYRAZOLE-4-CARBOXAMIDE
CYTOKINETICS, INC.
2021 Phase 2 EUCTR2020-003571-17-IT Italy;Spain;United States;
2020 Phase 2 EUCTR2019-002785-12-IT Italy;Netherlands;Spain;United Kingdom;United States;
(R)-N-(5-(5-ETHYL-1,2,4-OXADIAZOL-3-YL)-2,3-DIHYDRO-1H-INDEN-1-YL)-1METHYL-1HPYRAZOLE-4-CARBOXAMIDE
CYTOKINETICS, INC.
2021 Phase 2 EUCTR2020-003571-17-IT Italy;Spain;United States;
1-(2,3,4-Trimethoxybenzyl)piperazine dihydrochloride
University College London (UCL)
2011 - EUCTR2011-000038-12-GB United Kingdom;
3D electrocardiographic mapping (ECM)
University Hospital, Bordeaux
2015 - NCT02559726 France;
Adenosine
Duke University
2017 Phase 4 NCT03249272 United States;
Air
University Hospital, Bordeaux
2019 - NCT04129905 France;
Alcohol
Beijing Anzhen Hospital, Capital Medical University
2021 - ChiCTR2000041464 China;
Sir Run Run Shaw Hospital, Zhejiang University School of Medicine
2020 Phase 0 ChiCTR2000033626 China;
Alcohol Septal Ablation
St. Antonius Hospital
2021 - NCT04684290 Netherlands;
Alcohol septal ablation
Steen Hvitfeldt Poulsen
2019 - NCT04066777 Denmark;
Amyl nitrite inhalation
Mayo Clinic
2021 - NCT04905173 United States;
Antiarrhythmic drugs
Institute of Cardiology, Warsaw, Poland
2009 Phase 3 NCT00821353 Poland;
Aspirin
Ottawa Heart Institute Research Corporation
2016 Phase 3 NCT02674958 Canada;
Atorvastatin
University of Calgary
2007 Phase 3 NCT00317967 Canada;
B-lines SE
Fatebenefratelli Hospital
2016 - NCT03049995 Italy;
BNP blood sample test
University Hospital, Bordeaux
2019 - NCT04129905 France;
C01EB18
OSPEDALE SAN RAFFAELE
2016 Phase 2 EUCTR2015-004402-42-IT Italy;
CAS Name: 1,4-Benzoxazepin-5(2H)-one, 3,4-dihydro-4-(2-pyrimidinylmethyl)-7-[4- (trifluoromethoxy)phenyl] IUPAC Name: 4-(Pyrimidin-2-ylmethyl)-7-[4- (trifluoromethoxy)phenyl]-3,4-dihydro-1,4-benzoxazepin-5(2H)-one
Gilead Sciences, Inc.
2015 Phase 2 EUCTR2013-004429-97-GB Australia;France;Germany;Israel;Italy;Netherlands;United Kingdom;United States;
CAS Name: 1,4-Benzoxazepin-5(2H)-one, 3,4-dihydro-4-(2-pyrimidinylmethyl)-7-[4-(trifluoromethoxy)phenyl] IUPAC Name: 4-(Pyrimidin-2-ylmethyl)-7-[4-(trifluoromethoxy)phenyl]-3,4-dihydro-1,4-benzoxazepin-5(2H)-one
Gilead Sciences, Inc.
2015 Phase 2 EUCTR2013-004429-97-NL France;Germany;Israel;Italy;Netherlands;United Kingdom;United States;
2015 Phase 2 EUCTR2013-004429-97-IT France;Germany;Israel;Italy;Netherlands;United Kingdom;United States;
2015 Phase 2 EUCTR2013-004429-97-GB Australia;France;Germany;Israel;Italy;Netherlands;United Kingdom;United States;
CK-3773274
CYTOKINETICS, INC.
2021 Phase 2 EUCTR2020-003571-17-IT Italy;Spain;United States;
2020 Phase 2 EUCTR2019-002785-12-IT Italy;Netherlands;Spain;United Kingdom;United States;
Cytokinetics, Inc.
2021 Phase 2 EUCTR2020-003571-17-ES Italy;Spain;United States;
2020 Phase 2 EUCTR2019-002785-12-GB Italy;Netherlands;Spain;United Kingdom;United States;
2020 Phase 2 EUCTR2019-002785-12-ES Italy;Netherlands;Spain;United Kingdom;United States;
- Phase 2 EUCTR2019-002785-12-NL Italy;Netherlands;Spain;United Kingdom;United States;
Ji Xing Pharmaceuticals (Shanghai) Co., Ltd.
2021 Phase 1 NCT04783766 China;
CK-3773274 (10 - 30 mg)
Cytokinetics
2020 Phase 2 NCT04219826 Italy;Netherlands;Spain;United States;
CK-3773274 (5 - 15 mg)
Cytokinetics
2020 Phase 2 NCT04219826 Italy;Netherlands;Spain;United States;
CK-3773274 (5 - 20 mg)
Cytokinetics
2021 Phase 2 NCT04848506 Italy;Spain;United States;
CK-3773274 (5 mg, 10 mg, 15 mg and 20 mg)
Cytokinetics
2022 Phase 3 NCT05186818 United States;
CK-3773274 - Granules in Capsule
Cytokinetics
2018 Phase 1 NCT03767855 United States;
CK-3773274 - Tablets
Cytokinetics
2018 Phase 1 NCT03767855 United States;
CT-G20
Celltrion
2020 Phase 1 NCT04418297 Korea, Republic of;Poland;United States;
Candesartan
Charles University, Czech Republic
2007 Phase 2 NCT00430833 Czech Republic;
The First Affiliated Hospital, Sun Yat-sen University
2018 Phase 4 study ChiCTR-IIR-17013661 China;
Carnitine
University Health Network, Toronto
2013 Phase 4 NCT01904396 Canada;
Cibenzoline
TOA EIYO LTD.
2019 Phase 2 JPRN-JapicCTI-194910 Japan;
Coronary flow reserve SE
Fatebenefratelli Hospital
2016 - NCT03049995 Italy;
Cufence
Manchester University NHS Foundation Trust
2020 Phase 2 EUCTR2020-002242-17-GB United Kingdom;
Cyclosporine A
National Heart, Lung, and Blood Institute (NHLBI)
1999 Phase 2 NCT00001965 United States;
Diastolic function SE
Fatebenefratelli Hospital
2016 - NCT03049995 Italy;
Diltiazem
Brigham and Women's Hospital
2006 Phase 2/Phase 3 NCT00319982 United States;
Diovan
National Heart, Lung, and Blood Institute / National Institutes of Health
2016 Phase 2 EUCTR2015-002283-16-DK Denmark;
Dobutamine
University of Aarhus
2011 Phase 4 NCT01375335 Denmark;
Echo and myocardial contrast echocardiography perfusion imaging
Oregon Health and Science University
2015 - NCT02560467 United States;
Echocardiography (TEE)
University Hospital, Bordeaux
2015 - NCT02559726 France;
Eleclazine
Gilead Sciences
2015 Phase 2/Phase 3 NCT02291237 Australia;France;Germany;Israel;Italy;Netherlands;United Kingdom;United States;
Endothelial function biomarkers
University Hospital, Bordeaux
2019 - NCT04129905 France;
Entresto
Novartis Farmacéutica, S.A.
2020 Phase 2 EUCTR2019-003098-24-ES Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
Novartis Pharma AG
2020 Phase 2 EUCTR2019-003098-24-GR Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
2020 Phase 2 EUCTR2019-003098-24-GB Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
2020 Phase 2 EUCTR2019-003098-24-FI Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
2019 Phase 2 EUCTR2019-003098-24-DE Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
Esmolol
Meshalkin Research Institute of Pathology of Circulation
2021 Phase 4 NCT05073094 Russian Federation;
GS-6615
Gilead Sciences, Inc.
2015 Phase 2 EUCTR2013-004429-97-NL France;Germany;Israel;Italy;Netherlands;United Kingdom;United States;
2015 Phase 2 EUCTR2013-004429-97-IT France;Germany;Israel;Italy;Netherlands;United Kingdom;United States;
GS-6615 3 mg Pink
Gilead Sciences, Inc.
2015 Phase 2 EUCTR2013-004429-97-GB Australia;France;Germany;Israel;Italy;Netherlands;United Kingdom;United States;
GS-6615 3 mg White
Gilead Sciences, Inc.
2015 Phase 2 EUCTR2013-004429-97-GB Australia;France;Germany;Israel;Italy;Netherlands;United Kingdom;United States;
GS-6615 6 mg White
Gilead Sciences, Inc.
2015 Phase 2 EUCTR2013-004429-97-GB Australia;France;Germany;Israel;Italy;Netherlands;United Kingdom;United States;
Gold
Beijing Chaoyang Hospital, Capital Medical University
2021 Phase 0 ChiCTR2100048388 China;
Gutron 2,
CHU de Bordeaux
2015 - EUCTR2015-003521-34-FR France;
Hyperpolarized 13C-Pyruvate
University of Texas Southwestern Medical Center
2018 - NCT03057002 United States;
IMB-1018972
Imbria Pharmaceuticals, Inc.
2021 Phase 2 NCT04826185 United Kingdom;United States;
IMUKIN - 6 FLACONI 0.5 ML 100 MCG
ASSOCIAZIONE LA NOSTRA FAMIGLIA - SEZIONE SCIENTIFICA I.R.C.C.S. E.MEDEA
2016 Phase 2 EUCTR2015-002432-40-IT Italy;
Insertable cardiac monitor
Region Gävleborg
2017 - NCT03259113 Sweden;
LCZ696
Novartis Farmacéutica, S.A.
2020 Phase 2 EUCTR2019-003098-24-ES Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
Novartis Pharma AG
2020 Phase 2 EUCTR2019-003098-24-GR Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
2020 Phase 2 EUCTR2019-003098-24-GB Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
2020 Phase 2 EUCTR2019-003098-24-FI Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
2019 Phase 2 EUCTR2019-003098-24-DE Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
Novartis Pharmaceuticals
2020 Phase 2 NCT04164732 Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
Left ventricular contractile reserve SE
Fatebenefratelli Hospital
2016 - NCT03049995 Italy;
Left ventricular outflow tract gradient SE
Fatebenefratelli Hospital
2016 - NCT03049995 Italy;
Losartan
Henning Bundgaard
2011 Phase 2 NCT01447654 Denmark;
Massachusetts General Hospital
2007 Phase 2 NCT01150461 United States;
National Heart, Lung, and Blood Institute (NHLBI)
1996 - NCT00001534 United States;
Losartan Bluefish
Hjertemedicinsk klinik B, 2142, Rigshospitalet
2011 - EUCTR2011-001191-19-DK Denmark;
MEK162
Array Biopharma, now a wholly owned subsidiary of Pfizer
2012 Phase 2 NCT01556568 United Kingdom;United States;
Novartis Pharma Services AG
2012 - EUCTR2011-003392-10-GB United Kingdom;United States;
METOPROLOL SUCCINATE
Aarhus University Hospital
2018 Phase 2 EUCTR2017-004478-32-DK Denmark;
MIDODRINE HYDROCHLORIDE
CHU de Bordeaux
2015 - EUCTR2015-003521-34-FR France;
MYK-461
MYOKARDIA, INC.
2019 Phase 3 EUCTR2018-004039-64-IT Belgium;Czechia;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2018 Phase 3 EUCTR2017-002530-23-IT Belgium;Czech Republic;Czechia;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
MyoKardia, Inc.
2019 Phase 3 EUCTR2018-004039-64-PT Belgium;Czechia;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2019 Phase 3 EUCTR2018-004039-64-PL Belgium;Czechia;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2019 Phase 3 EUCTR2018-004039-64-NL Belgium;Czechia;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2019 Phase 3 EUCTR2018-004039-64-GB Belgium;Czech Republic;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2019 Phase 3 EUCTR2018-004039-64-ES Belgium;Czech Republic;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2019 Phase 3 EUCTR2018-004039-64-DK Belgium;Czechia;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2019 Phase 3 EUCTR2018-004039-64-DE Belgium;Czechia;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2019 Phase 3 EUCTR2018-004039-64-BE Belgium;Czechia;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2018 Phase 3 EUCTR2017-002530-23-PT Belgium;Czech Republic;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2018 Phase 3 EUCTR2017-002530-23-PL Belgium;Czech Republic;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2018 Phase 3 EUCTR2017-002530-23-NL Belgium;Czech Republic;Czechia;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2018 Phase 3 EUCTR2017-002530-23-GB Belgium;Czech Republic;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2018 Phase 3 EUCTR2017-002530-23-FR Belgium;Czech Republic;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2018 Phase 3 EUCTR2017-002530-23-ES Belgium;Czech Republic;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2018 Phase 3 EUCTR2017-002530-23-DK Belgium;Czech Republic;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2018 Phase 3 EUCTR2017-002530-23-DE Belgium;Czech Republic;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2018 Phase 3 EUCTR2017-002530-23-CZ Belgium;Czech Republic;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2018 Phase 3 EUCTR2017-002530-23-BE Belgium;Czech Republic;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2016 Phase 2 NCT02842242 United States;
2014 Phase 1 NCT02329184 United States;
Magnetic resonance imaging (MRI) with gadolinium enhancement
University Hospital, Bordeaux
2015 - NCT02559726 France;
Magnetic resonance imaging (MRI) without gadolinium enhancement
University Hospital, Bordeaux
2015 - NCT02559726 France;
Mangafodipir
University of Edinburgh
2018 - NCT03607669 United Kingdom;
Mavacamten
LianBio LLC
2022 Phase 3 NCT05174416 China;
2021 Phase 1 NCT05135871 China;
MYOKARDIA, INC.
2018 Phase 3 EUCTR2017-002530-23-IT Belgium;Czech Republic;Czechia;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
MyoKardia, Inc.
2020 Phase 3 NCT04349072 United States;
2018 Phase 3 NCT03470545 Belgium;Czechia;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2018 Phase 2/Phase 3 NCT03723655 Belgium;Czechia;Denmark;France;Germany;Israel;Italy;Netherlands;Poland;Portugal;Spain;United Kingdom;United States;
2018 Phase 2 NCT03496168 United States;
2018 Phase 2 NCT03442764 United States;
Metoprolol
The First Affiliated Hospital, Sun Yat-sen University
2018 Phase 4 study ChiCTR-IIR-17013661 China;
University Hospital, Motol
2020 Phase 4 NCT04133532 Czechia;
Metoprolol Succinate
Steen Hvitfeldt Poulsen
2018 Phase 2 NCT03532802 Denmark;
Metoprololsuccinat
Aarhus University Hospital
2018 Phase 2 EUCTR2017-004478-32-DK Denmark;
Mitral regurgitation SE
Fatebenefratelli Hospital
2016 - NCT03049995 Italy;
N-acetylcysteine
The University of Texas Health Science Center, Houston
2012 Phase 1 NCT01537926 United States;
NO
West China Hospital, Sichuan University
2019 - ChiCTR1900021706 China;
PERINDOPRIL ARGININA
AZIENDA OSPEDALIERO-UNIVERSITARIA CAREGGI
2017 Phase 2 EUCTR2015-004317-24-IT Italy;
PROCAPTAN - 10 MG COMPRESSE RIVESTITE CON FILM 60 COMPRESSE IN CONTENITORE PER COMPRESSE PP
AZIENDA OSPEDALIERO-UNIVERSITARIA CAREGGI
2017 Phase 2 EUCTR2015-004317-24-IT Italy;
PROCAPTAN - 5 MG COMPRESSE RIVESTITE CON FILM 10 COMPRESSE IN CONTENITORE PER COMPRESSE PP
AZIENDA OSPEDALIERO-UNIVERSITARIA CAREGGI
2017 Phase 2 EUCTR2015-004317-24-IT Italy;
Perhexiline
Flinders University
2020 Phase 2 NCT04426578 Australia;
Heart Metabolics Limited
2015 Phase 3 NCT02431221 -
University Hospital Birmingham
2006 Phase 2 NCT00500552 United Kingdom;
Perindopril arginine
AZIENDA OSPEDALIERO-UNIVERSITARIA CAREGGI
2017 Phase 2 EUCTR2015-004317-24-IT Italy;
Perxexiline
University Hospital of Birmingham Foundation Trust
2005 - EUCTR2005-000755-15-GB United Kingdom;
Pexsig
University Hospital of Birmingham Foundation Trust
2005 - EUCTR2005-000755-15-GB United Kingdom;
Phosphorous
University of East Anglia
2017 Phase 1 NCT03251287 United Kingdom;
Pirfenidone
National Heart, Lung, and Blood Institute (NHLBI)
2001 Phase 2 NCT00011076 United States;
Pre and post-CPB Drug: Dobutamine Hydrochloride
University Health Network, Toronto
2021 Phase 4 NCT05025644 -
Pulmonary hemodynamics SE
Fatebenefratelli Hospital
2016 - NCT03049995 Italy;
RANEXA - 750 MG - COMPRESSA A RILASCIO PROLUNGATO- USO ORALE - BLISTER (PVC/PVDC/ALLUMINIO) 60 COMPRESSE
OSPEDALE SAN RAFFAELE
2016 Phase 2 EUCTR2015-004402-42-IT Italy;
RANEXA*60CPR 500MG R.P.
MENARINI INTERNATIONAL OPERATIONS LUXEMBOURG S.A.
2012 Phase 2 EUCTR2011-004507-20-IT Germany;Italy;Spain;
RANEXA*60CPR 750MG R.P.
MENARINI INTERNATIONAL OPERATIONS LUXEMBOURG S.A.
2012 Phase 2 EUCTR2011-004507-20-IT Germany;Italy;Spain;
RAS
Shanghai Children's Medical Center affiliated to Shanghai Jiao Tong University School of Medicine
2021 - ChiCTR2000041243 China;
RF catheter ablation
Institute of Cardiology, Warsaw, Poland
2009 Phase 3 NCT00821353 Poland;
Ranexa
Menarini International Operations Luxembourg S.A.
2012 - EUCTR2011-004507-20-ES Germany;Italy;Spain;
2012 - EUCTR2011-004507-20-DE Germany;Italy;Spain;
Ranolazina Ranexa
OSPEDALE SAN RAFFAELE
2016 Phase 2 EUCTR2015-004402-42-IT Italy;
Ranolazine
Duke University
2012 Phase 4 NCT01721967 United States;
Ranolazine 1000 mg PR tablets
Menarini International Operations Luxembourg S.A.
2012 - EUCTR2011-004507-20-ES Germany;Italy;Spain;
2012 - EUCTR2011-004507-20-DE Germany;Italy;Spain;
Ranolazine 500 mg PR tablets
Menarini International Operations Luxembourg S.A.
2012 - EUCTR2011-004507-20-ES Germany;Italy;Spain;
2012 - EUCTR2011-004507-20-DE Germany;Italy;Spain;
Ranolazine 750 mg PR tablets
Menarini International Operations Luxembourg S.A.
2012 - EUCTR2011-004507-20-ES Germany;Italy;Spain;
2012 - EUCTR2011-004507-20-DE Germany;Italy;Spain;
Ranolazine PR (prolonged-release) 500 mg 1 tablet bis in die and 750 mg 1 tablet bis in die
IRCCS San Raffaele
2016 Phase 2 NCT03953989 Italy;
Regadenoson
Duke University
2017 Phase 4 NCT03249272 United States;
SACUBITRIL VALSARTAN
Novartis Farmacéutica, S.A.
2020 Phase 2 EUCTR2019-003098-24-ES Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
Novartis Pharma AG
2020 Phase 2 EUCTR2019-003098-24-GR Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
2020 Phase 2 EUCTR2019-003098-24-GB Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
2020 Phase 2 EUCTR2019-003098-24-FI Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
2019 Phase 2 EUCTR2019-003098-24-DE Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
Sacubitril/Valsartan
Newcastle University
2019 Phase 2 NCT03832660 Germany;Italy;Serbia;United Kingdom;
Sacubitril/valsartan
Novartis Farmacéutica, S.A.
2020 Phase 2 EUCTR2019-003098-24-ES Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
Novartis Pharma AG
2020 Phase 2 EUCTR2019-003098-24-GR Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
2020 Phase 2 EUCTR2019-003098-24-GB Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
2020 Phase 2 EUCTR2019-003098-24-FI Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
2019 Phase 2 EUCTR2019-003098-24-DE Finland;Germany;Greece;Korea, Republic of;Spain;United Kingdom;United States;
Spironolactone
Tufts Medical Center
2007 Phase 4 NCT00879060 United States;
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
2018 Phase 4 NCT02948998 China;
Surgical Septal Myectomy
St. Antonius Hospital
2021 - NCT04684290 Netherlands;
TY-0305
TOA EIYO LTD.
2019 Phase 2 JPRN-JapicCTI-194910 Japan;
Trans-right ventricular alcohol septal ablation (TRVASA)
National Heart, Lung, and Blood Institute (NHLBI)
2002 Phase 2 NCT00035386 United States;
Treatment BX1514M
University Hospital, Bordeaux
2015 Phase 2 NCT02590809 France;
Trientine
Manchester University NHS Foundation Trust
2020 Phase 2 NCT04706429 United Kingdom;
2020 Phase 2 EUCTR2020-002242-17-GB United Kingdom;
Triethylinetetramine dihydrochloride
Manchester University NHS Foundation Trust
2020 Phase 2 EUCTR2020-002242-17-GB United Kingdom;
Trimetazidine
University College, London
2012 Phase 2 NCT01696370 United Kingdom;
Use of bioanalytical assay to monitor plasma levels of perhexiline
Heart Metabolics Limited
2016 Phase 2 NCT02862600 United States;
Valsartan
HealthCore-NERI
2014 Phase 2 NCT01912534 Canada;United States;
Vastarel
VU University Medical Center
2018 Phase 2 EUCTR2018-000029-29-NL Netherlands;
Vastarel 20mg film coated tablets
University College London (UCL)
2011 - EUCTR2011-000038-12-GB United Kingdom;