8. Huntington disease Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 242 / Drugs : 205 - (DrugBank : 62) / Drug target genes : 85 - Drug target pathways : 159
Huntington disease and other diseases between which drug repositioning might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Drug repositionability
ID | Diseases (Sorted by drug repositionability) |
---|---|
8 | Huntington disease |
6 | Parkinson disease |
13 | Multiple sclerosis/Neuromyelitis optica |
2 | Amyotrophic lateral sclerosis |
46 | Malignant rheumatoid arthritis |
206 | Fragile X syndrome |
97 | Ulcerative colitis |
140 | Dorabe syndrome |
17 | Multiple system atrophy |
156 | Rett syndrome |
144 | Lennox-Gastaut syndrome |
96 | Crohn disease |
5 | Progressive supranuclear palsy |
21 | Mitochondrial disease |
18 | Spinocerebellar degeneration |
193 | Prader-Willi syndrome |
70 | Spinal stenosis |
3 | Spinal muscular atrophy |
145 | West syndrome |
22 | Moyamoya disease |
205 | Fragile X syndrome related disease |
34 | Neurofibromatosis |
201 | Angelman syndrome |
152 | PCDH19 related syndrome |
113 | Muscular dystrophy |
298 | Hereditary pancreatitis |
84 | Sarcoidosis |
231 | Alpha-1-antitrypsin deficiency |
36 | Epidermolysis bullosa |
203 | 22q11.2 deletion syndrome |
158 | Tuberous sclerosis |
272 | Fibrodysplasia ossificans progressiva |
98 | Eosinophilic gastrointestinal disease |
127 | Frontotemporal lobar degeneration |
155 | Acquired aphasia with convulsive disorder |
86 | Pulmonary arterial hypertension |
75 | Cushing disease |
296 | Biliary atresia |
299 | Cystic fibrosis |
78 | Hypopituitarism |
4 | Primary lateral sclerosis |
85 | Idiopathic interstitial pneumonia |
226 | Interstitial cystitis with Hunners ulcer |
107 | Juvenile idiopathic arthritis |
118 | Myelomeningocele |
51 | Scleroderma |
49 | Systemic lupus erythematosus |
28 | Systemic amyloidosis |
149 | Hemiconvulsion hemiplegia epilepsy syndrome |
169 | Menkes disease |
170 | Occipital horn syndrome |
215 | Tetralogy of Fallot |
254 | Porphyria |
323 | Aromatic L-amino acid decarboxylase deficiency |
265 | Lipodystrophy |
168 | Ehlers-Danlos syndrome |
179 | Williams syndrome |
280 | Huge arteriovenous malformation with cervicofacial or limb lesion |
271 | Ankylosing spondylitis |
1 | Spinal and bulbar muscular atrophy |
10 | Charcot-Marie-Tooth disease |
288 | Autoimmune acquired coagulation factor deficiency |
309 | Progressive myoclonus epilepsy |
87 | Pulmonary veno-occlusive disease |
88 | Chronic thromboembolic pulmonary hypertension |
11 | Myasthenia gravis |
256 | Muscle glycogenosis |
77 | Growth hormone secreting pituitary adenoma |
282 | Congenital dyserythropoietic anemia |
120 | Hereditary dystonia |
210 | Single Ventricle |
58 | Hypertrophic cardiomyopathy |
162 | Pemphigoid |
90 | Retinitis pigmentosa |
38 | Stevens-Johnson syndrome |
67 | Polycystic kidney disease |
114 | Non-dystrophic myotonia syndrome |
65 | Primary immunodeficiency |
20 | Adrenoleukodystrophy |
187 | Kabuki syndrome |
171 | Wilson disease |
222 | Primary nephrotic syndrome |
212 | Tricuspid atresia |
63 | Idiopathic thrombocytopenic purpura |
89 | Lymphangioleiomyomatosis |
246 | Methylmalonic acidemia |
57 | Idiopathic dilated cardiomyopathy |
7 | Corticobasal degeneration |
91 | Budd-Chiari syndrome |
202 | Smith-Magenis syndrome |
71 | Idiopathic osteonecrosis of the femoral head |
324 | Methylglutaconic aciduria |