DR info

Clinical trials : 1,205 / Drugs : 684 - (DrugBank : 124) / Drug target genes : 100 - Drug target pathways : 193

Pulmonary arterial hypertension and other diseases between which drug repositioning might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Drug repositionability

ID	Diseases (Sorted by drug repositionability)
86	Pulmonary arterial hypertension
13	Multiple sclerosis/Neuromyelitis optica
6	Parkinson disease
2	Amyotrophic lateral sclerosis
225	Congenital nephrogenic diabetes insipidus
46	Malignant rheumatoid arthritis
51	Scleroderma
114	Non-dystrophic myotonia syndrome
85	Idiopathic interstitial pneumonia
90	Retinitis pigmentosa
230	Alveolar hypoventilation syndrome
96	Crohn disease
58	Hypertrophic cardiomyopathy
67	Polycystic kidney disease
299	Cystic fibrosis
97	Ulcerative colitis
113	Muscular dystrophy
115	Hereditary periodic paralysis
154	Epilepsy with continuous spikes and waves during slow sleep
226	Interstitial cystitis with Hunners ulcer
89	Lymphangioleiomyomatosis
88	Chronic thromboembolic pulmonary hypertension
127	Frontotemporal lobar degeneration
34	Neurofibromatosis
28	Systemic amyloidosis
70	Spinal stenosis
81	Congenital adrenal hyperplasia
8	Huntington disease
49	Systemic lupus erythematosus
65	Primary immunodeficiency
210	Single Ventricle
222	Primary nephrotic syndrome
298	Hereditary pancreatitis
156	Rett syndrome
256	Muscle glycogenosis
84	Sarcoidosis
155	Acquired aphasia with convulsive disorder
5	Progressive supranuclear palsy
167	Marfan syndrome
53	Sjogren syndrome
19	Lysosomal storage disease
140	Dorabe syndrome
17	Multiple system atrophy
107	Juvenile idiopathic arthritis
168	Ehlers-Danlos syndrome
57	Idiopathic dilated cardiomyopathy
98	Eosinophilic gastrointestinal disease
193	Prader-Willi syndrome
1	Spinal and bulbar muscular atrophy
211	Hypoplastic left heart syndrome
74	Prolactin secreting pituitary adenoma
66	IgA nephropathy
218	Alport syndrome
83	Addison disease
35	Pemphigus
144	Lennox-Gastaut syndrome
227	Osler disease
87	Pulmonary veno-occlusive disease
215	Tetralogy of Fallot
280	Huge arteriovenous malformation with cervicofacial or limb lesion
254	Porphyria
296	Biliary atresia
11	Myasthenia gravis
10	Charcot-Marie-Tooth disease
15	Inclusion body myositis
285	Fanconi anemia
278	Huge lymphatic malformation with cervicofacial lesion
206	Fragile X syndrome
271	Ankylosing spondylitis
331	Idiopathic multicentric castleman disease
288	Autoimmune acquired coagulation factor deficiency
75	Cushing disease
231	Alpha-1-antitrypsin deficiency
169	Menkes disease
170	Occipital horn syndrome
50	Dermatomyositis
36	Epidermolysis bullosa
26	HTLV-1-associated myelopathy
38	Stevens-Johnson syndrome
300	IgG4-related disease
78	Hypopituitarism
41	Giant cell arteritis
233	Wolfram syndrome
149	Hemiconvulsion hemiplegia epilepsy syndrome
158	Tuberous sclerosis
251	Urea cycle disorder
309	Progressive myoclonus epilepsy
71	Idiopathic osteonecrosis of the femoral head
3	Spinal muscular atrophy
22	Moyamoya disease
118	Myelomeningocele
77	Growth hormone secreting pituitary adenoma
337	Homocystinuria
257	Hepatic glycogenosis
282	Congenital dyserythropoietic anemia
63	Idiopathic thrombocytopenic purpura
228	Bronchiolitis obliterans
301	Macular dystrophy
157	Sturge-Weber syndrome
166	Pseudoxanthoma elasticum
294	Congenital diaphragmatic hernia
224	Purpura nephritis
64	Thrombotic thrombocytopenic purpura
265	Lipodystrophy
60	Aplastic anemia
76	Pituitary gonadotropin secretion hyperthyroidism
47	Buerger disease
94	Primary sclerosing cholangitis
162	Pemphigoid
164	Oculocutaneous albinism
310	Congenital anomalies syndrome
229	Autoimmune pulmonary alveolar proteinosis
102	Rubinstein-Taybi syndrome
284	Diamond-Blackfan anemia
20	Adrenoleukodystrophy
56	Behcet disease
43	Microscopic polyangiitis
61	Autoimmune hemolytic anemia
212	Tricuspid atresia
272	Fibrodysplasia ossificans progressiva
21	Mitochondrial disease
7	Corticobasal degeneration
179	Williams syndrome
106	Cryopyrin-associated periodic syndrome
91	Budd-Chiari syndrome
283	Acquired pure red cell aplasia
137	Focal cortical dysplasia
192	Cockayne syndrome
277	Lymphangiomatosis
281	Klippel-Trenaunay-Weber syndrome
111	Congenital myopathy
54	Adult still disease
52	Mixed connective tissue disease
220	Rapidly progressive glomerulonephritis
30	Distal myopathy